Abstract:
:The activity of central vestibular neurons (Vn) of the horizontal canal system was recorded in chronically hemilabyrinthectomized cats and compared with that of labyrinth intact animals. In both groups the cerebellar vermis was removed in order to assess the efficacy of the vestibular brainstem commissure alone by means of polarizing currents applied to the labyrinths. Experiments were carried out under Ketamine anaesthesia. In control animals the mean resting rates of type I and type II Vn measured 22.4 +/- 14.0 and 27.5 +/- 14.6 imp/s respectively, and the type I responses occurred ca. 3 X more frequently than type II. In the lesioned animals a drastic reduction of the number of type I responses was found on the deafferented side, while that on the intact side remained normal. The resting rates of type I Vn on the two sides did not differ significantly from each other but were significantly lower than those of control animals. In contrast, type II responses were present on the deafferented side, but almost completely missing on the intact side. Applying polarizing stimuli in control animals, it was found that both labyrinths have similar weight in driving Vn. In lesioned animals, no major changes in the efficacy of the commissural path were found when polarizing stimuli were applied to the intact side. It is concluded that vestibular nerve section causes a severe loss of type I responses in the vestibular nuclei on the side of the lesion which apparently is not compensated by an adaptive change in the commissural path and, therefore, may be mainly responsible for the VOR asymmetry observed concomitantly.
journal_name
Acta Otolaryngoljournal_title
Acta oto-laryngologicaauthors
Ried S,Maioli C,Precht Wdoi
10.3109/00016488409107529subject
Has Abstractpub_date
1984-07-01 00:00:00pages
1-13issue
1-2eissn
0001-6489issn
1651-2251journal_volume
98pub_type
杂志文章abstract::Background: If the pulsatile tinnitus caused by sigmoid sinus diverticulum/dehiscence cannot be diagnosed and treated, it can lead to significant morbidity and mortality.Aim: To assess the sandwich surgical technique for sigmoid sinus wall reconstruction for the treatment of pulsatile tinnitus caused by sigmoid sinus ...
journal_title:Acta oto-laryngologica
pub_type: 杂志文章
doi:10.1080/00016489.2019.1668960
更新日期:2019-12-01 00:00:00
abstract::The inner ear responds immunologically to foreign proteins and pathogens introduced into the cochlea. The route of entry of the cells participating in the inner ear inflammatory process is the spiral modiolar vein with its collecting venules. Since this vein is located adjacent to the scala tympani, the end result of ...
journal_title:Acta oto-laryngologica
pub_type: 杂志文章,评审
doi:10.3109/00016489009107455
更新日期:1990-11-01 00:00:00
abstract::The effects of two simulated hearing impairments (presbyacusis) on speech perception were investigated in two groups of normally hearing subjects (30 and 48 subjects, respectively). Eight patients with presbyacusis with similar hearing impairment to those in the latter simulation served as the clinical material. Word ...
journal_title:Acta oto-laryngologica
pub_type: 杂志文章
doi:10.1080/000164800750000991
更新日期:2000-03-01 00:00:00
abstract::We investigated the effect of prolonged hypergravity on the otoconial layer of the maculae utriculi and the maculae sacculi in hamsters. The animals were placed in a centrifuge under conditions of 2.5 G, and remained there for 6 months. We then determined the calcium contents of the otoconia with energy dispersive X-r...
journal_title:Acta oto-laryngologica
pub_type: 杂志文章
doi:10.3109/00016489509139297
更新日期:1995-03-01 00:00:00
abstract::Background: Amyloidosis is a benign, slowly progressive disease. However, the treatment of laryngeal amyloidosis (LA) has not been studied systematically.Objectives: To investigate the treatment results of cold micro forceps or carbon dioxide laser under microlaryngoscope in the treatment of LA.Methods: A retrospectiv...
journal_title:Acta oto-laryngologica
pub_type: 杂志文章
doi:10.1080/00016489.2019.1680864
更新日期:2019-12-01 00:00:00
abstract:CONCLUSION:This study demonstrated that five Cx26 mutations (R32H, S199F, 572delT, 631-632delGT, and Y155X) affect gap junction (GJ) functions by causing impaired membrane targeting and aberrant cellular localization, and one mutation (R165W) leads to a constriction of the channel pore with no dye coupling. OBJECTIVE:...
journal_title:Acta oto-laryngologica
pub_type: 杂志文章
doi:10.3109/00016489.2010.506885
更新日期:2011-01-01 00:00:00
abstract::There have been many morphological investigations on the generation of respiratory epithelium. However, the mucociliary activity of fetal respiratory epithelium has never yet been discussed. In the present work, ciliary activity and mucociliary function in the nose and the trachea of fetal rabbits were studied and, mo...
journal_title:Acta oto-laryngologica
pub_type: 杂志文章
doi:10.3109/00016488409130999
更新日期:1984-03-01 00:00:00
abstract::The gram negative bacteria, nontypable Haemophilus influenzae (NTHi) was used to induce otitis media in a total of 18 chinchillas. Three days post-inoculation, three cohorts of 6 chinchillas each were treated daily for four days with either ceftriaxone, chloramphenicol, or diluent without antibiotics. Middle ear fluid...
journal_title:Acta oto-laryngologica
pub_type: 杂志文章
doi:10.3109/00016489709118000
更新日期:1997-01-01 00:00:00
abstract::Evidence for a common anatomical and physiological substrate for the generation of the background EEG and the vertex-evoked response led to the hypothesis that the EEG can be interpreted as the output from a time varying filter driven by (a) a noise generator responsible for the background activity, and (b) a pulse ge...
journal_title:Acta oto-laryngologica
pub_type: 杂志文章
doi:10.3109/00016487709128834
更新日期:1977-01-01 00:00:00
abstract:BACKGROUND:As tympanotomy using the transcanal approach was a routine surgical technique for traumatic ossicular disruption, the efficacy of the posterior tympanum approach was rarely explored. AIM:This study aimed to investigate whether the hearing outcomes improved after simultaneous ossiculoplasty and facial nerve ...
journal_title:Acta oto-laryngologica
pub_type: 杂志文章
doi:10.1080/00016489.2020.1833081
更新日期:2020-11-05 00:00:00
abstract::The aerobic and anaerobic bacterial flora of middle ear exudate (MEE) of 47 consecutive patients with chronic suppurative otitis media were studied using a quantitative bacteriological technique under strictly anaerobic conditions. Specimens from the external auditory canal (EAC) and the nasopharynx (NP) were obtained...
journal_title:Acta oto-laryngologica
pub_type: 杂志文章
doi:10.3109/00016488609119425
更新日期:1986-11-01 00:00:00
abstract::The nasal airways of 94 healthy term infants (37-42 weeks gestational age) were examined by continuous wide-band noise acoustic rhinometry under standardized conditions on the second or third day postpartum. Validation of the flexible infant probe on tubular plastic models with dimensions similar to the nasal cavity o...
journal_title:Acta oto-laryngologica
pub_type: 杂志文章
doi:10.3109/00016489709113416
更新日期:1997-05-01 00:00:00
abstract:BACKGROUND:Tinnitus treatments present a quandary for clinicians, but no thoroughly satisfactory medical treatments are offered to tinnitus patients. OBJECTIVE:We compared sound therapy effects of the broad band noise (BBN) and the mixed pure tones on tinnitus patients with normal to mild hearing loss, and the possibl...
journal_title:Acta oto-laryngologica
pub_type: 杂志文章,随机对照试验
doi:10.1080/00016489.2019.1575522
更新日期:2019-03-01 00:00:00
abstract::The microsphere method was used to measure the inner ear blood flow in albino rabbits before and during artificial ventilation with 5% CO2 in air. An increase in blood flow resulted in both the cochlear and the vestibular parts of the inner ear. ...
journal_title:Acta oto-laryngologica
pub_type: 杂志文章
doi:10.3109/00016488709134692
更新日期:1987-01-01 00:00:00
abstract::Blood circulation in the cochlear lateral wall after exposure to a non-physiological level of sound (120-125 dB SPL, 3 h) was investigated immunohistologically. Kanamycin (KM), which was expected to function as a tracer of blood flow, was administered to guinea pigs 5 min to 21 h after sound termination. At 5-30 min, ...
journal_title:Acta oto-laryngologica
pub_type: 杂志文章
doi:10.3109/00016489109137358
更新日期:1991-01-01 00:00:00
abstract::We investigated the redistribution of facial motor neurons after recovery from a crush injury of the facial nerve in the mongolian gerbil, with the retrograde transportation of horseradish peroxidase (HRP) technique. The facial nerve at the vertical segment was crushed unilaterally for 10 s with forceps. After 1 month...
journal_title:Acta oto-laryngologica
pub_type: 杂志文章
doi:10.3109/00016489509139307
更新日期:1995-03-01 00:00:00
abstract::Human papillomavirus (HPV) has a well-established association with benign and malignant cervical tumours as well as with laryngeal papillomas, while its association with laryngeal carcinomas is still controversial. We have examined 39 squamous cell carcinomas of the larynx for HPV using PCR with three consensus primer...
journal_title:Acta oto-laryngologica
pub_type: 杂志文章
doi:10.3109/00016489609137949
更新日期:1996-11-01 00:00:00
abstract::There is no single technique for reconstruction of the canal wall following radical mastoidectomy. Autograft tissues may be unsuitable because of resorption and limited availability. An ideal foreign implant material should be bone-like in quality, non-ototoxic, readily available and malleable. Plaster of Paris, a deg...
journal_title:Acta oto-laryngologica
pub_type: 杂志文章
doi:10.3109/00016488609108631
更新日期:1986-05-01 00:00:00
abstract::Conventional (visual) analysis of EMG was compared to a computerized quantitative method (turns/amplitude). Ten patients with a clinical history of peripheral nerve lesion were examined in order to investigate whether quantitative analysis of EMG increased the diagnostic sensitivity of peripheral nerve lesions to the ...
journal_title:Acta oto-laryngologica
pub_type: 杂志文章
doi:10.3109/00016489409126023
更新日期:1994-01-01 00:00:00
abstract::The occurrence of horizontal jerks with larger amplitudes than on Earth was observed during vertical optokinetic nystagmus in astronauts tested throughout a 7-day spaceflight. During early exposure to microgravity, a horizontal spontaneous-like nystagmus was recorded in darkness following both vertical and horizontal ...
journal_title:Acta oto-laryngologica
pub_type: 杂志文章
doi:10.3109/00016489009107432
更新日期:1990-03-01 00:00:00
abstract:OBJECTIVE:Temperature-controlled radiofrequency volumetric tissue reduction (RFVTR) is a minimally invasive technique used in the treatment of the tongue base, soft palate and turbinates. Complications seem to be rare, but the scope of previous studies was often limited by the small number of patients included. The aim...
journal_title:Acta oto-laryngologica
pub_type: 杂志文章
doi:10.1080/00016480310001385
更新日期:2003-05-01 00:00:00
abstract::The objective of this study was to determine whether methylcobalamin inhibits the ototoxic action of gentamicin. Fourteen pigmented guinea pigs were randomly divided into experimental and control groups. Each animal in the experimental group was given a large single dose of gentamicin (125 mg/kg i.m.), followed by imm...
journal_title:Acta oto-laryngologica
pub_type: 杂志文章
doi:10.1080/000164801300102752
更新日期:2001-04-01 00:00:00
abstract:OBJECTIVE:To determine the role of cell proliferation neoplastic progression in the larynx and possibly derive criteria of clinical significance using automated quantitative image analysis. MATERIAL AND METHODS:In a retrospective study involving archival material, the occurrence and location, size, shape and staining ...
journal_title:Acta oto-laryngologica
pub_type: 杂志文章
doi:10.1080/0001648021000028135
更新日期:2003-08-01 00:00:00
abstract::The inner ear distortion induced by gentamicin (GM), a type of aminoglycoside antibiotic, was examined in guinea-pigs. Previous studies which investigated the function of the eighth cranial nerve and organ of Corti using cochlear microphonics (CM) and compound action potential (CAP) reported ototoxicity following expe...
journal_title:Acta oto-laryngologica
pub_type: 杂志文章
doi:10.1080/00016489850183449
更新日期:1998-06-01 00:00:00
abstract::Most epidemiological surveys concerning populations exposed to occupational noise or random populations have shown that the left ear is slightly but significantly poorer than the right ear, especially at frequencies most susceptible to noise damage. To experimentally study the possible left-right asymmetry in response...
journal_title:Acta oto-laryngologica
pub_type: 杂志文章
doi:10.3109/00016489109138399
更新日期:1991-01-01 00:00:00
abstract:BACKGROUND:Smell and taste disorders occur in COVID-19 with a high prevalence, but little is known about the duration of the symptoms. In particular, studies using validated olfactory tests are very rare to date. AIMS/OBJECTIVES:The aim of this study was to determine the olfactory function of COVID-19 recoveries by a ...
journal_title:Acta oto-laryngologica
pub_type: 杂志文章
doi:10.1080/00016489.2020.1811999
更新日期:2020-12-01 00:00:00
abstract:CONCLUSIONS:The procedure cleared the lesion completely and preserved the physiological function of the external auditory canal. OBJECTIVE:To develop a novel surgical procedure to treat chronic suppurative otitis media (CSOM). To explore the merit of using pedicled temporalis myofascia (PTM) and reconstruction of the ...
journal_title:Acta oto-laryngologica
pub_type: 杂志文章
doi:10.3109/00016489.2013.767987
更新日期:2013-07-01 00:00:00
abstract::Patients with Bell's palsy were investigated with regard to the cellular immune response during the acute and convalescent stages with the purpose of acquiring information concerning the etiology of the condition. In order to ascertain whether there was activation of the immune system, the proportion of activated T ce...
journal_title:Acta oto-laryngologica
pub_type: 杂志文章
doi:10.3109/00016488809119452
更新日期:1988-01-01 00:00:00
abstract::The influence of obstructed nasal passages was investigated in l4 patients with allergic rhinitis. Disordered breathing in sleep was found in all patients in the form of periodic breathing, and hypopneic and hyperpneic episodes, associated with characteristic "microarousals' from sleep. Patients had an average of 50 "...
journal_title:Acta oto-laryngologica
pub_type: 杂志文章
doi:10.3109/00016488109133292
更新日期:1981-11-01 00:00:00
abstract::The early diagnosis of the Mondini dysplasia by means of electrocochleography and temporal bone polytomography, and the prevention of further hearing loss through the endolymphatic subarachnoid shunt operation, brought new data on the follow-up of patients with this malformation. They were found to present specific me...
journal_title:Acta oto-laryngologica
pub_type: 杂志文章
doi:10.3109/00016488309139454
更新日期:1983-05-01 00:00:00