Abstract：
:Levels of contraceptive steroids in breast milk and plasma of lactating women were investigated. 7 lactating women received 150 mg medroxyprogesterone acetate (MPA) 1 week after delivery. 5 women (lactating) took 350 mcg norethisterone (NET) and 2 took 150 mcg d-norgestrel (d-ng) + 30 mcg ethinyl estradiol. Milk and blood samples were drawn and radioimmunoassay of the contraceptive drug levels were performed. In all 7 women taking MPA, drug was detected in the breast milk and plasma in a ratio of 1:1 for a period of 87 days. NET was also present in milk and plasma but the concentration in milk was about 1/10 of the amount in plasma. d-Ng levels were also less than 1/10 that in plasma.
journal_name
Contraceptionjournal_title
Contraceptionauthors
Saxena BN,Shrimanker K,Grudzinskas JGdoi
10.1016/0010-7824(77)90061-0subject
Has Abstractpub_date
1977-12-01 00:00:00pages
605-13issue
6eissn
0010-7824issn
1879-0518pii
0010-7824(77)90061-0journal_volume
16pub_type
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