Abstract:
:The mathematical model of steady-state iron kinetics in the human presented here extends the use of radioactive tracer observations in the determination of erythron maturative and proliferative behavior. Functions descriptive of that behavior appear explicitly in the model together with functions customarily measured in standard tracer procedures. The model is compartmental, with transfers compatible with all observed erythropoietic and hemolytic mechanisms as well as with most plausible conjunctured mechanisms. Obtainable from the model is quantitative information about iron uptake, intermitotic intervals, and maturation time of erythrons; about intra- and extramedullary hemolysis; and about certain standard exchange rates. The model also permits tests of competing conjectures about erythron behavior.
journal_name
Biophys Jjournal_title
Biophysical journalauthors
Nooney GCdoi
10.1016/S0006-3495(65)86750-9subject
Has Abstractpub_date
1965-11-01 00:00:00pages
755-65issue
6eissn
0006-3495issn
1542-0086pii
S0006-3495(65)86750-9journal_volume
5pub_type
杂志文章abstract::A number of properties of certain living embryonic tissues can be explained by considering them as liquids. Tissue fragments left in a shaker bath round up to form spherical aggregates, as do liquid drops. When cells comprising two distinct embryonic tissues are mixed, typically a nucleation-like process takes place, ...
journal_title:Biophysical journal
pub_type: 杂志文章
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journal_title:Biophysical journal
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pub_type: 杂志文章
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更新日期:2004-10-01 00:00:00
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更新日期:1996-06-01 00:00:00
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更新日期:2013-08-06 00:00:00
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pub_type: 杂志文章
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更新日期:2016-09-20 00:00:00
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更新日期:2000-02-01 00:00:00
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更新日期:2011-08-03 00:00:00
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更新日期:2012-11-07 00:00:00
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journal_title:Biophysical journal
pub_type: 杂志文章
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更新日期:2005-08-01 00:00:00
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更新日期:2012-04-18 00:00:00
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pub_type: 信件
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更新日期:2008-06-01 00:00:00
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更新日期:2011-07-06 00:00:00