Five-year analysis of adenovirus 8 antibody levels in an industrial community following an outbreak of keratoconjunctivitis.

Abstract:

:Serum hemagglutination-inhibition (HI) antibody titers were monitored for five years with samples from 79 keratoconjunctivitis patients with type 8 adenovirus (AV-8) infection. Geometric mean antibody titers declined from 1:161 at the peak of the epidemic to 1:56 after five years. Computerized analysis of the decline in geometric mean antibody titer indicates that most patients will have a serum HI titer of 1:25 by 10 years after their clinical infection. These residual antibody levels and the consistent failure to document re-infection with AV-8 suggest that recurrent episodes of keratoconjunctivitis are caused by adenovirus serotypes other than type 8.

journal_name

Am J Epidemiol

authors

Hierholzer JC,Sprague JB

doi

10.1093/oxfordjournals.aje.a112797

subject

Has Abstract

pub_date

1979-08-01 00:00:00

pages

132-40

issue

2

eissn

0002-9262

issn

1476-6256

journal_volume

110

pub_type

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