Vernal conjunctivitis and contact lens-associated giant papillary conjunctivitis compared and contrasted.

Abstract:

:We compared quantitative histologic counts of ten subjects with vernal conjunctivitis to counts of 15 subjects with contact lens-associated giant papillary conjunctivitis and to counts of 15 normal subjects. Both vernal conjunctivitis and contact lens-associated giant papillary conjunctivitis subjects had abnormalities of mast cells in the epithelium, and eosinophils and basophils in epithelium and substantia propria. No normal individuals had these abnormalities. An additional 28 subjects with ocular inflammatory conditions had tissue evaluation for abnormalities of mast cells, eosinophils, and basophils. A few eosinophils were found in four subjects. The histologic abnormalities of vernal conjunctivitis are shared by contact lens-associated giant papillary conjunctivitis but not by conjunctival inflammation in general. Vernal conjunctivitis and contact lens-associated giant papillary conjunctivitis may represent different subtypes of a general category of conjunctival abnormality characterized by giant papillae.

journal_name

Am J Ophthalmol

authors

Allansmith MR,Baird RS,Greiner JV

doi

10.1016/0002-9394(79)90247-2

subject

Has Abstract

pub_date

1979-04-01 00:00:00

pages

544-55

issue

4

eissn

0002-9394

issn

1879-1891

pii

0002-9394(79)90247-2

journal_volume

87

pub_type

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