Abstract:
:The influence of basic open-loop synaptic connections on the firing of simultaneously recorded neurons has been investigated with auto- and cross-correlation histograms, using experimental records and computer simulations. The basic connections examined were direct synaptic excitation, direct synaptic inhibition, and shared synaptic input. Each type of synaptic connection produces certain characteristic features in the cross-correlogram depending on the properties of the synapse and statistical features in the firing pattern of each neuron. Thus, empirically derived cross-correlation measures can be interpreted in terms of the underlying physiological mechanisms. Their potential uses and limitations in the detection and identification of synaptic connections between neurons whose extracellularly recorded spike trains are available are discussed.
journal_name
Biophys Jjournal_title
Biophysical journalauthors
Moore GP,Segundo JP,Perkel DH,Levitan Hdoi
10.1016/S0006-3495(70)86341-Xsubject
Has Abstractpub_date
1970-09-01 00:00:00pages
876-900issue
9eissn
0006-3495issn
1542-0086pii
S0006-3495(70)86341-Xjournal_volume
10pub_type
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