Isolation and characterization of mesenchymal cells from human fetal membranes.

abstract：:Unique poly(l-lactic acid) (PLLA)-based scaffolds were constructed by embedding knitted PLLA yarns within a bioresorbable and differentially crosslinked three-dimensional (3D) oxidized collagen scaffold. The scaffolds were designed specifically for the repair of complex incisional abdominal wall hernias and the repair...

journal_title：Journal of tissue engineering and regenerative medicine

authors： Pu F,Rhodes NP,Bayon Y,Hunt JA

更新日期：2016-10-01 00:00:00

abstract：:Tissue engineering holds great promise to develop functional constructs resembling the structural organization of native tissues to improve or replace biological functions, with the ultimate goal of avoiding organ transplantation. In tissue engineering, cells are often seeded into artificial structures capable of supp...

journal_title：Journal of tissue engineering and regenerative medicine

authors： Khorshidi S,Solouk A,Mirzadeh H,Mazinani S,Lagaron JM,Sharifi S,Ramakrishna S

更新日期：2016-09-01 00:00:00

abstract：:Chronic proteolytic disruption of elastic fibres within the abdominal aortic wall results in wall vessel expansion to form rupture-prone abdominal aortic aneurysms (AAA). Arresting AAA growth is not possible as adult vascular smooth muscle cells (SMCs) poorly auto-regenerate and repair elastic fibres. Thus, there is a...

journal_title：Journal of tissue engineering and regenerative medicine

authors： Swaminathan G,Stoilov I,Broekelmann T,Mecham R,Ramamurthi A

更新日期：2018-01-01 00:00:00

abstract：:In the context of prevascularization strategies for tissue-engineering purposes, co-culture systems consisting of outgrowth endothelial cells (OECs) and primary osteoblasts (pOBs) have been established as a promising in vitro tool to study regeneration mechanisms and to identify factors that might positively influence...

journal_title：Journal of tissue engineering and regenerative medicine

authors： Dohle E,El Bagdadi K,Sader R,Choukroun J,James Kirkpatrick C,Ghanaati S

更新日期：2018-03-01 00:00:00

abstract：:Damage of non-vascularised tissues such as cartilage and cornea can result in healing processes accompanied by a non-physiological angiogenesis. Peptidic aptamers have recently been reported to block the vascular endothelial growth factor (VEGF). However, the therapeutic applications of these aptamers are limited due ...

journal_title：Journal of tissue engineering and regenerative medicine

authors： Perugini V,Guildford AL,Silva-Correia J,Oliveira JM,Meikle ST,Reis RL,Santin M

更新日期：2018-02-01 00:00:00

abstract：:Nonvascularized fat grafting is a valuable technique for soft tissue reconstruction but poor survival of fat in the host environment remains a problem. A process known as cell-assisted transfer is used to enhance fat graft retention by adding stromal vascular fraction, an adipose-derived stem cell (ASC) rich content t...

journal_title：Journal of tissue engineering and regenerative medicine

authors： Tan SS,Zhan W,Poon CJ,Han X,Marre D,Boodhun S,Palmer JA,Mitchell GM,Morrison WA

更新日期：2018-02-01 00:00:00

abstract：:The ability to control facial skin physiology and appearance through the oral mucosa (transbuccally) is largely unexplored. Here, a hypothesis was tested that transbuccal delivery of fat tissue-supportive actives may trigger beneficial cosmetic responses at the level of the skin. First, the importance of the fat tissu...

journal_title：Journal of tissue engineering and regenerative medicine

authors： Bojanowski K,Ma S,Applebaum R,Zhao H

更新日期：2020-08-01 00:00:00

abstract：:In this communication, we introduce boron nitride nanotube (BNNT)-functionalised muscle cell/microfibre mesh constructs, obtained via tissue engineering, as a three-dimensional (3D) platform to study a wireless stimulation system for electrically responsive cells and tissues. Our stimulation strategy exploits the piez...

journal_title：Journal of tissue engineering and regenerative medicine

authors： Danti S,Ciofani G,Pertici G,Moscato S,D'Alessandro D,Ciabatti E,Chiellini F,D'Acunto M,Mattoli V,Berrettini S

更新日期：2015-07-01 00:00:00

abstract：:Fracture haematoma formation is the first and foremost important stage of fracture healing. It orchestrates the inflammatory and cellular processes leading to the formation of callus and the restoration of the continuity of the bone. Evidence suggests that blocking this initial stage could lead to an impairment of the...

journal_title：Journal of tissue engineering and regenerative medicine

authors： Walters G,Pountos I,Giannoudis PV

更新日期：2018-03-01 00:00:00

abstract：BACKGROUND:According to experimental studies, mesh implants may reduce in size up to 50.8% during their integration into soft tissues. This results in impaired mobility of the anterior abdominal wall and hernia recurrences, as well as affects patients' quality of life. Due to unsatisfactory radiographic contrast of pol...

journal_title：Journal of tissue engineering and regenerative medicine

authors： Shemyatovsky KA,Azimov RH,Alekhin AI,Kazantsev AA,Alekhin AA

更新日期：2020-05-01 00:00:00

abstract：:Postoperative mucosal regeneration of the middle ear cavity and the mastoid cavity is of great importance after middle ear surgery. However, the epithelialization of the mucosa in the middle ear is retarded because chronic inflammation without epithelialization aggravates gas exchange and clinical function. These envi...

journal_title：Journal of tissue engineering and regenerative medicine

authors： Hama T,Yamamoto K,Yaguchi Y,Murakami D,Sasaki H,Yamato M,Okano T,Kojima H

更新日期：2017-04-01 00:00:00

abstract：:For the success of any biomaterial for tissue engineering, its mechanical properties and ability to support nutrient diffusion will be critical. Collagen scaffolds are ideal candidates, due to their ability to immerse cells in a biomimetic nanofibrous matrix. We have established O(2) diffusion coefficients through nat...

journal_title：Journal of tissue engineering and regenerative medicine

authors： Cheema U,Rong Z,Kirresh O,Macrobert AJ,Vadgama P,Brown RA

更新日期：2012-01-01 00:00:00

abstract：:Cleft palate is one of the most common craniofacial defects in newborn babies. The characteristics of this genetic disease produce soft and hard tissue defects on the lip and maxilla, which cause not only aesthetic but also functional problems with speech, eating, and breathing. Bone grafts using autologous cancellous...

journal_title：Journal of tissue engineering and regenerative medicine

authors： Lee JM,Kim HY,Park JS,Lee DJ,Zhang S,Green DW,Okano T,Hong JH,Jung HS

更新日期：2019-02-01 00:00:00

abstract：:Current cardiac cell therapies cannot effectively target and retain cells in a specific area of the heart. Cell-seeded biological sutures were previously developed to overcome this limitation, demonstrating targeted delivery with > 60% cell retention. In this study, both cell-seeded and non-seeded fibrin-based biologi...

journal_title：Journal of tissue engineering and regenerative medicine

authors： Tao ZW,Favreau JT,Guyette JP,Hansen KJ,Lessard J,Burford E,Pins GD,Gaudette GR

更新日期：2017-01-01 00:00:00

abstract：:Clinical translation of engineered tissues into regenerative medicine applications, and the effort to reduce the use of animals for the screening of drugs and other compounds, result in an increasing demand for human tissues engineered in vitro for implantation, in vitro screening systems and basic research. Further d...

journal_title：Journal of tissue engineering and regenerative medicine

authors： Rouwkema J,Gibbs S,Lutolf MP,Martin I,Vunjak-Novakovic G,Malda J

更新日期：2011-08-01 00:00:00

abstract：:Peripheral human nerves fail to regenerate across long tube implants (>2 cm), and tissue-engineered nerve grafts represent a promising treatment alternative. The present study aims to investigate the testosterone propionate (TP) repair effect of acellular nerve allograft (ANA) seeded with allogeneic bone marrow mesenc...

journal_title：Journal of tissue engineering and regenerative medicine

authors： Chen C,Tian Y,Wang J,Zhang X,Nan L,Dai P,Gao Y,Zheng S,Liu W,Zhang Y

更新日期：2019-09-01 00:00:00

abstract：:Despite the spontaneous regenerative capacity of the peripheral nervous system, large gap peripheral nerve injuries (PNIs) require bridging strategies. The limitations and suboptimal results obtained with autografts or hollow nerve conduits in the clinic urge the need for alternative treatments. Recently, we have desc...

journal_title：Journal of tissue engineering and regenerative medicine

authors： Sanen K,Martens W,Georgiou M,Ameloot M,Lambrichts I,Phillips J

更新日期：2017-12-01 00:00:00

abstract：:For preventing the scar contracture of host tissue and adjusting the tensile strength of covering cell sheets, a controlled collagen crosslinking step process in the preparation of skin-fibroblast sheets for repairing wound was investigated by using β-aminopropionitrile (BAPN), a collagen crosslinking inhibitor, in th...

journal_title：Journal of tissue engineering and regenerative medicine

authors： Kanzaki M,Yamato M,Takagi R,Kikkawa T,Isaka T,Okano T,Onuki T

更新日期：2013-05-01 00:00:00

abstract：:This work reports the effects of phosphoserine addition on the biodegradability of calcium phosphate cements. The characteristics of a phosphoserine-modified calcium phosphate cement without collagen in a large animal model are presented here for the first time. Critical size bone defects in the proximal tibia of 10 s...

journal_title：Journal of tissue engineering and regenerative medicine

authors： Offer L,Veigel B,Pavlidis T,Heiss C,Gelinsky M,Reinstorf A,Wenisch S,Lips KS,Schnettler R

更新日期：2011-01-01 00:00:00

abstract：:The effects of mesenchymal stem cells (MSCs) on the phenotype and function of natural killer T (NKT) cells is not understood. We used concanavalin A (Con A) and α-galactosylceramide (α-GalCer)-induced liver injury to evaluate the effects of MSCs on NKT-dependent hepatotoxicity. Mouse MSCs (mMSCs) significantly reduced...

journal_title：Journal of tissue engineering and regenerative medicine

authors： Gazdic M,Simovic Markovic B,Vucicevic L,Nikolic T,Djonov V,Arsenijevic N,Trajkovic V,Lukic ML,Volarevic V

更新日期：2018-02-01 00:00:00

abstract：:The regeneration and establishment of osseointegration within oral peri-implant bone defects remains a clinical challenge. Bone tissue engineering (BTE) is emerging as a promising alternative to autogenous and/or biomaterial-based bone grafting. The objective of this systematic review was to answer the focused questio...

journal_title：Journal of tissue engineering and regenerative medicine

authors： Shanbhag S,Pandis N,Mustafa K,Nyengaard JR,Stavropoulos A

更新日期：2018-01-01 00:00:00

abstract：:Tissue engineering applications require an appropriate combination of a cell population, biochemical factors and scaffold materials. In this field, mesenchymal stem cells (MSCs) emerge as an attractive cell population, due to their ready availability and their potential to be differentiated into various mesodermal cel...

journal_title：Journal of tissue engineering and regenerative medicine

authors： Sart S,Errachid A,Schneider YJ,Agathos SN

更新日期：2013-07-01 00:00:00

abstract：:The advances achieved by cell-based therapies to treat autoimmune diseases such as rheumatoid arthritis (RA) and multiple sclerosis (MS), despite promising, are still insufficient for the current demands. RA and MS therapeutic approaches follow world guidelines to use disease modifying drugs and biological agents that...

journal_title：Journal of tissue engineering and regenerative medicine

authors： Rodrigues DB,Oliveira JM,Santos TC,Reis RL

更新日期：2018-03-01 00:00:00

abstract：:Carbonate apatite-coated calcium carbonate (CO3 Ap/CaCO3 ) was fabricated through a dissolution-precipitation reaction using CaCO3 granules as a precursor to accelerate bone replacement based on superior osteoconductivity of the CO3 Ap shell, along with Ca2+ release from the CaCO3 core and quicker resorption of the Ca...

journal_title：Journal of tissue engineering and regenerative medicine

authors： Fujioka-Kobayashi M,Tsuru K,Nagai H,Fujisawa K,Kudoh T,Ohe G,Ishikawa K,Miyamoto Y

更新日期：2018-10-01 00:00:00

abstract：:In this study, a simple three-dimensional (3D) suspension culture method for the expansion and cardiac differentiation of human induced pluripotent stem cells (hiPSCs) is reported. The culture methods were easily adapted from two-dimensional (2D) to 3D culture without any additional manipulations. When hiPSCs were dir...

journal_title：Journal of tissue engineering and regenerative medicine

authors： Haraguchi Y,Matsuura K,Shimizu T,Yamato M,Okano T

更新日期：2015-12-01 00:00:00

abstract：:A feasibility study was undertaken to examine the potential of biodegradable HEMA-lactate-dextran (HEMA-LLA-D)-based cryogels as scaffolds for cartilage tissue engineering. This was a preliminary in vitro study giving essential information on the biocompatibility of cryogels with cartilage cells. HEMA-lactate (HEMA-LL...

journal_title：Journal of tissue engineering and regenerative medicine

authors： Bölgen N,Yang Y,Korkusuz P,Güzel E,El Haj AJ,Pişkin E

更新日期：2011-11-01 00:00:00

abstract：:The development of a functional microvasculature is critical to the long-term survival of implanted tissue-engineered constructs. Dynamic culture conditions have been shown to significantly modulate phenotypic characteristics and stimulate proliferation of cells within hydrogel-based tissue engineered blood vessels. A...

journal_title：Journal of tissue engineering and regenerative medicine

authors： Gassman AA,Kuprys T,Ucuzian AA,Brey E,Matsumura A,Pang Y,Larson J,Greisler HP

更新日期：2011-05-01 00:00:00

abstract：:Transplantation of bone marrow mesenchymal stem cells (BMSCs) has been considered to be a promising strategy for wound healing. However, poor viability of engrafted BMSCs and limited capabilities of differentiation into the desired cell types in wounds often hinder its application. Few studies report the induction of ...

journal_title：Journal of tissue engineering and regenerative medicine

authors： Shou K,Huang Y,Qi B,Hu X,Ma Z,Lu A,Jian C,Zhang L,Yu A

更新日期：2018-02-01 00:00:00

abstract：:The composition and organization of the vocal fold extracellular matrix (ECM) provide the viscoelastic mechanical properties that are required to sustain high-frequency vibration during voice production. Although vocal injury and pathology are known to produce alterations in matrix physiology, the mechanisms responsib...

journal_title：Journal of tissue engineering and regenerative medicine

authors： Kutty JK,Webb K

更新日期：2010-01-01 00:00:00

abstract：:Native articular cartilage is subjected to synovial fluid flow during normal joint function. Thus, it is believed that the morphogenesis of articular cartilage may be positively regulated by the application of similar stimulation in vitro. In the present study, the effect of fluid flow over the chondrogenic differenti...

journal_title：Journal of tissue engineering and regenerative medicine

authors： Alves da Silva ML,Martins A,Costa-Pinto AR,Correlo VM,Sol P,Bhattacharya M,Faria S,Reis RL,Neves NM

更新日期：2011-10-01 00:00:00