Abstract:
:Effects of various doses (0-250 micrograms/kg, SC) of estradiol-17 beta (E2) in a two-bottle choice conditioned taste aversion and a two-compartment conditioned place preference procedure were studied in male and female rats. Dose-dependent taste aversion and place aversion effects of E2 were established, and the conditioned taste aversion procedure was found to be more sensitive in detecting aversive properties of E2 than the conditioned place preference procedure. Although aversive properties of E2 were found in both sexes, the effects were clearly more prominent in males as compared to females. From this study, it was concluded that E2 acts as an unconditioned aversive stimulus in both male and female rats capable of gaining control over different types of behavior by associative learning.
journal_name
Physiol Behavjournal_title
Physiology & behaviorauthors
de Beun R,Jansen E,Smeets MA,Niesing J,Slangen JL,van de Poll NEdoi
10.1016/0031-9384(91)90427-psubject
Has Abstractpub_date
1991-11-01 00:00:00pages
995-1000issue
5eissn
0031-9384issn
1873-507Xpii
0031-9384(91)90427-Pjournal_volume
50pub_type
杂志文章abstract::Lean, preweanling Zucker rat pups increase neuropeptide Y (NPY) expression in the hypothalamic arcuate nucleus in response to a 24-h deprivation of food, water, and maternal interaction as early as postnatal day 2 (P2). In this study, we examined if replacing nutritive or tactile aspects of maternal behavior to depriv...
journal_title:Physiology & behavior
pub_type: 杂志文章
doi:10.1016/s0031-9384(02)00644-3
更新日期:2002-03-01 00:00:00
abstract::Animals sampled from the third generation (S3) of selective breeding of N:NIH strain rats based on ultrasonic vocalization (USV) rates in infancy (High, Low, and Random lines) were tested as adults on the elevated plus maze, a well-validated test of anxiety. Results showed that the Low line spent a greater percent of ...
journal_title:Physiology & behavior
pub_type: 杂志文章
doi:10.1016/0031-9384(95)02222-8
更新日期:1996-07-01 00:00:00
abstract::Olfactory bulbectomy (OBX) in rats produces behavioral, physiological, and neurochemical changes that resemble symptoms of depression in humans. The procedure thus serves as a rodent model of affective disorder. Many of the behavioral effects of OBX resemble psychomotor agitation. The possible role of dysregulation of...
journal_title:Physiology & behavior
pub_type: 杂志文章
doi:10.1016/j.physbeh.2004.01.003
更新日期:2004-03-01 00:00:00
abstract::The variation of food intake and digestive tract contents over a period of 24 hours was measured in the free feeding rat kept under a 12:12 hr light:dark cycle (lights on at 0700 hr). After a cessation between 0700 and 1000 hr, the rate of food intake increased progressively during daytime followed by a marked increas...
journal_title:Physiology & behavior
pub_type: 杂志文章
doi:10.1016/0031-9384(87)90164-8
更新日期:1987-01-01 00:00:00
abstract::An operant chamber has been developed for studying lever-press conditioning in the green crab Carcinus maenas. In one series of experiments, animals were presented with a single bar and were reinforced with food for every bar press. Performance increased over time and high rates of responding were observed after 2 day...
journal_title:Physiology & behavior
pub_type: 杂志文章
doi:10.1016/0031-9384(90)90311-q
更新日期:1990-08-01 00:00:00
abstract::Intermale aggression is a natural form of psychosocial stress that can alter a variety of physiological functions, including immune function. In Experiment 1, daily fighting between pairs of previously isolated male mice differentially altered immunological measures of T-cell responsiveness in dominant and submissive ...
journal_title:Physiology & behavior
pub_type: 杂志文章
doi:10.1016/0031-9384(90)90378-h
更新日期:1990-06-01 00:00:00
abstract::Mean arterial pressure (MAP), heart rate (HR), plasma epinephrine (E), plasma norepinephrine (NE), and plasma corticosterone (CORT) were measured in 3-month- and 24-month-old male Wistar rats exposed to a conditioned emotional stress response (CER) paradigm and a conditioned defensive burying (CDB) paradigm. In the CE...
journal_title:Physiology & behavior
pub_type: 杂志文章
doi:10.1016/0031-9384(92)90120-q
更新日期:1992-04-01 00:00:00
abstract::This study aimed to investigate long-term stability and variability of diurnal cortisol and alpha-amylase patterns. Diurnal cortisol and alpha-amylase secretion patterns were assessed on a single workday with three waves of measurement across a total time period of 24months in 189 participants. Separate hierarchical l...
journal_title:Physiology & behavior
pub_type: 杂志文章
doi:10.1016/j.physbeh.2017.03.021
更新日期:2017-06-01 00:00:00
abstract::Ethanol is a common dietary constituent, but knowledge of its chemosensory properties and their relationship to its ingestion is limited. Twenty-five male and 25 female, light-regular ethanol consumers participated in five test sessions. Sessions involved determination of taste, olfactory and nasal irritation threshol...
journal_title:Physiology & behavior
pub_type: 杂志文章
doi:10.1016/s0031-9384(00)00397-8
更新日期:2001-01-01 00:00:00
abstract::Three different techniques were used to study the effects of 72 hr deprivation of paradoxical sleep on percentages total sleep, light slow wave sleep, deep slow wave sleep and paradoxical sleep during deprivation and recovery periods in rats. The paradoxical sleep deprivation methods used were the classical platform, ...
journal_title:Physiology & behavior
pub_type: 杂志文章
doi:10.1016/0031-9384(86)90341-0
更新日期:1986-01-01 00:00:00
abstract:OBJECTIVE:Larger food portions lead to increased intake but the mechanism behind this effect is unclear. We investigated the effect of portion size on bite size, eating rate, deceleration rate, and meal duration. DESIGN AND METHODS:Thirty-seven overweight women attended 5 visits after a 3 h fast and consumed a 229, 30...
journal_title:Physiology & behavior
pub_type: 杂志文章
doi:10.1016/j.physbeh.2014.11.041
更新日期:2015-02-01 00:00:00
abstract::This study was designed to determine the differences between young and elderly people on the perceived intensity and pleasantness of sucrose in foods, in relation to their food intake. First, a group of 35 young subjects (mean age: 22 +/- 2 years) and 29 elderly subjects (mean age: 79 +/- 6 years) judged the intensity...
journal_title:Physiology & behavior
pub_type: 杂志文章
doi:10.1016/s0031-9384(96)00306-x
更新日期:1996-12-01 00:00:00
abstract::Thyroid hormones play an important role in brain development. In the present study, we examined the influence of transient postnatal hypothyroidism on reproductive neuroendocrine and behavioral outcomes in the male Syrian (golden) hamster. Hamster pups were rendered hypothyroid following exposure to the goitrogen, 6-n...
journal_title:Physiology & behavior
pub_type: 杂志文章
doi:10.1016/j.physbeh.2006.12.017
更新日期:2007-04-23 00:00:00
abstract::Vitamin D has been shown in a wide variety of species to play critical roles in neurodevelopment. Vitamin D deficiency disrupts development of the brain and can cause lasting behavioral dysfunction. Zebrafish have become an important model for the study of development in general and neurodevelopment in particular. Zeb...
journal_title:Physiology & behavior
pub_type: 杂志文章
doi:10.1016/j.physbeh.2020.113016
更新日期:2020-10-01 00:00:00
abstract::Feather pecking in domestic fowl is a behavioral abnormality that consists of mild or injurious pecking at feathers of conspecifics. Previously, it was shown that chicks from a high feather-pecking (HFP) and low feather-pecking (LFP) line of laying hens already differ in their propensity to feather peck at 14 and 28 d...
journal_title:Physiology & behavior
pub_type: 杂志文章
doi:10.1016/s0031-9384(02)00667-4
更新日期:2002-04-15 00:00:00
abstract::Consistent individual differences in animals' responses to different stressful situations may indicate the involvement of a single behavioural and neurological mechanism across these situations. Two replicate groups of sixteen food restricted pigs were subjected to a group feeding competition test where group members ...
journal_title:Physiology & behavior
pub_type: 杂志文章
doi:10.1016/0031-9384(91)90535-v
更新日期:1991-09-01 00:00:00
abstract::Yawning is a familiar and phylogenetically widespread phenomenon, but no consensus exists regarding its functional significance. We tested the hypothesis that yawning communicates to others a transition from a state of physiological and/or psychological arousal (for example, due to action of a stressor) to a more rela...
journal_title:Physiology & behavior
pub_type: 杂志文章
doi:10.1016/j.physbeh.2014.11.029
更新日期:2015-03-01 00:00:00
abstract::A ligation of the common bile duct (BDL) produces cholestasis and hypotension and increases the daily ingestion of sodium chloride solutions in rats. Low-dose captopril (CAP) treatment also modifies the ingestion of water and sodium in naive rats, and may do so in cholestatic rats. This study examined whether the elev...
journal_title:Physiology & behavior
pub_type: 杂志文章
doi:10.1016/s0031-9384(98)00295-9
更新日期:1999-05-01 00:00:00
abstract::Women in the reproductive age are more vulnerable to develop affective disorders than men. This difference may attribute to anatomical differences, hormonal influences and environmental factors such as stress. However, the higher prevalence in women normalizes once menopause is established, suggesting that ovarian hor...
journal_title:Physiology & behavior
pub_type: 杂志文章,评审
doi:10.1016/j.physbeh.2009.02.036
更新日期:2009-05-25 00:00:00
abstract::Male hooded rats were castrated and implanted with Silastic capsules (1.57 mm i.d.; 3.18 mm o.d.) having a testosterone-filled space 0, 7, 22, 60, or 90 mm long. All animals were returned to their original group cages for a three-week period to allow hormone concentrations and behavioral tendencies to stabilize. Each ...
journal_title:Physiology & behavior
pub_type: 杂志文章
doi:10.1016/0031-9384(90)90336-3
更新日期:1990-09-01 00:00:00
abstract::Aging is associated with a loss of the ability to maintain homeostasis in response to physiologic and environmental disturbances. Age-related dysregulation of food intake and energy balance appears to be the result of impaired responsiveness of hypothalamic integrative circuitry to metabolic cues, which can lead to la...
journal_title:Physiology & behavior
pub_type: 杂志文章,评审
doi:10.1016/j.physbeh.2006.05.032
更新日期:2006-06-30 00:00:00
abstract::Bilateral intracranial injections of puromycin (10 micrograms/0.5 microliter vehicle) into the preoptic area (POA) of steroid-primed ovariectomized rats resulted in a significant decrease in the lordosis response when compared to saline treated controls. To determine the extent of puromycin diffusion after intracrania...
journal_title:Physiology & behavior
pub_type: 杂志文章
doi:10.1016/0031-9384(84)90162-8
更新日期:1984-09-01 00:00:00
abstract::Diurnal patterns in the heart-rates (HR) of 16 wild European rabbits have been studied, based on more than 1200 days of radiotelemetrical HR recordings. HR shows a distinct diurnal rhythm which is closely coupled to the diurnal pattern of activity for free ranging animals. The rabbits' activity phase, accompanied by h...
journal_title:Physiology & behavior
pub_type: 杂志文章
doi:10.1016/0031-9384(88)90209-0
更新日期:1988-01-01 00:00:00
abstract::To examine the functional relationships between the dorsal raphe nucleus and the septum in the inhibitory regulation of feminine sexual behavior in male rats, castrated male rats received destruction of the dorsal raphe nucleus (DRL), interruption of the septal outputs (ARD), or both DRL and ARD (DRL+ARD). All animals...
journal_title:Physiology & behavior
pub_type: 杂志文章
doi:10.1016/0031-9384(94)90278-x
更新日期:1994-07-01 00:00:00
abstract::Rats injected with lithium chloride after exposure to a taste or olfactory stimulus learn stronger aversions to these cues if the drug is administered in two small injections 35 min apart than if all of the drug is given in a single injection. This facilitation of conditioning produced by distribution of the drug unco...
journal_title:Physiology & behavior
pub_type: 杂志文章
doi:10.1016/0031-9384(79)90203-8
更新日期:1979-11-01 00:00:00
abstract::GPRC6A is an amino acid-sensing receptor highly expressed in the brain and in skeletal muscle. Although recent evidence suggests that genetically engineered GPRC6A receptor knockout (KO) mice are susceptible to develop subtle endocrine and metabolic disturbances, the underlying disruptions in energy metabolism are lar...
journal_title:Physiology & behavior
pub_type: 杂志文章
doi:10.1016/j.physbeh.2013.05.015
更新日期:2013-06-13 00:00:00
abstract::We wanted to determine what happens to brain PCr and ATP relative to that in liver during a series of dietary manipulation consisting of a severe fast, during eating (when nutrients are intermittently supplied), and during and after PN-100, when an excess amount of nutrients are continuously supplied, using 31P-NMR sp...
journal_title:Physiology & behavior
pub_type: 杂志文章
doi:10.1016/0031-9384(95)00078-w
更新日期:1995-09-01 00:00:00
abstract::Although the involvement of two types of vasopressin (AVP) receptors, v1a and v1b, in neural regulation of social behavior is well documented in rodents, there is no report on combined actions of them in regulation of social behavior. In this study, we investigated behavioral differences between wild-type (WT) and v1a...
journal_title:Physiology & behavior
pub_type: 杂志文章
doi:10.1016/j.physbeh.2018.09.016
更新日期:2018-12-01 00:00:00
abstract::Repeated delivery of fast rise-time acoustic stimuli elicit cardiac changes in humans that reflect startle, orienting, and defense responses. To test the hypothesis that fast rise-time stimuli produce these responses in the rat, we evaluated magnitude, latency, and habituation of cardiovascular responses to brief airp...
journal_title:Physiology & behavior
pub_type: 杂志文章
doi:10.1016/0031-9384(96)00154-0
更新日期:1996-09-01 00:00:00
abstract::A causal relationship between declining nocturnal core temperature, increasing peripheral temperature, and sleep onset has been reported. The exact trigger for these thermoregulatory changes around sleep onset, however, is unknown. Our aim was to examine one possible trigger: prior knowledge of bedtime. Fourteen young...
journal_title:Physiology & behavior
pub_type: 杂志文章,随机对照试验
doi:10.1016/j.physbeh.2006.11.018
更新日期:2007-03-16 00:00:00