Abstract：
:Endogenous levels of salsolinol and dopamine were measured by a gas chromatography/mass spectrometry (GC/MS)--selected ion monitoring technique using deuterated internal standards in rats allowed to self-inject either acetaldehyde, ethanol or saline control solution over 20 days for 1 h/day. Significant increases in medial basal hypothalamic (MBH) and striatal salsolinol concentrations were found in animals exposed to acetaldehyde but not ethanol, whereas dopamine concentrations for these animals did not differ significantly from rats exposed to control conditions. The data provides further support for the in vivo formation of salsolinol following acetaldehyde exposure in experimental animals.
journal_name
Brain Resjournal_title
Brain researchauthors
Myers WD,Ng KT,Singer G,Smythe GA,Duncan MWdoi
10.1016/0006-8993(85)90955-2subject
Has Abstractpub_date
1985-12-09 00:00:00pages
122-8issue
1-2eissn
0006-8993issn
1872-6240pii
0006-8993(85)90955-2journal_volume
358pub_type
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