Mannan-binding lectin (MBL) serum concentration in relation to propagation of infectious bronchitis virus (IBV) in chickens.

abstract：:A 90-amino acid peptide from the simian rotavirus SA-11 nonstructural protein, NSP4 was linked to the N-terminus of the Ricinus communis A-B toxin B subunit protein (RTB) and synthesized in Escherichia coli. Recombinant RTB and the NSP4(90)::RTB fusion protein bound artificial receptor glycoprotein asialofetuin in an ...

journal_title：Viral immunology

authors： Choi NW,Estes MK,Langridge WH

更新日期：2006-04-01 00:00:00

abstract：:This study aimed to investigate the seroprevalence of cytomegalovirus (CMV) infection and risk factors associated with CMV acquisition among pregnant women in Zimbabwe. In a cross-sectional study, pregnant women were recruited in late gestation, seeking antenatal care at council clinics in three high-density suburbs i...

journal_title：Viral immunology

authors： Mhandire D,Duri K,Kaba M,Mhandire K,Musarurwa C,Chimusa E,Munjoma P,Mazengera L,Stray-Pedersen B,Dandara C

更新日期：2019-09-01 00:00:00

abstract：:Hepatitis E virus (HEV) is one of the primary causative agents of acute hepatitis. It is noteworthy that HEV can develop chronic infection and even lead to liver cirrhosis; however, the mechanism has not been revealed. In this study, the ELISA assay was used to detect protein levels, and we found that HEV open reading...

journal_title：Viral immunology

authors： Lei Q,Li L,Cai J,Huang W,Qin B,Zhang S

更新日期：2016-03-01 00:00:00

abstract：:To warrant potential clinical testing, the equine anti-severe acute respiratory syndrome coronavirus (SARS-CoV) F(ab')(2) requires evaluation in as many animal models as possible. In this study, we established a new animal model, the Chinese hamster, susceptible to SARS-CoV infection. SARS-CoV could propagate effectiv...

journal_title：Viral immunology

authors： Luo D,Ni B,Zhao G,Jia Z,Zhou L,Pacal M,Zhang L,Zhang S,Xing L,Lin Z,Wang L,Li J,Liang Y,Shi X,Zhao T,Zou L,Wu Y,Wang X

更新日期：2007-09-01 00:00:00

abstract：:There is limited information on the direct role of the neutralizing antibody responses against hepatitis C virus (HCV) infection or methodologies to study them. Previously we have demonstrated that interleukin-10 (IL-10) administered to chronic hepatitis patients led to a decrease in disease activity, but an increase ...

journal_title：Viral immunology

authors： Eksioglu EA,Bess J,Jones G,Dettloff J,Dangmeon P,Dong HJ,Zhu H,Firpi R,Xu Y,Nelson DR,Liu C

更新日期：2010-08-01 00:00:00

abstract：:We examined whether immunization with a single peptide induces cytotoxic T lymphocytes (CTLs) of heterogeneous specificities in vivo. Immunization of BALB/c mice with the peptide H2:529-537, which corresponded to amino acid residues 529-537 on the HA2 subunit transmembrane region of influenza A/Jap virus (H2N2) and po...

journal_title：Viral immunology

authors： Masaki H,Tamura M,Kurane I

更新日期：2000-01-01 00:00:00

abstract：:California (CAL) serogroup Bunyaviruses are significant agents of arboviral encephalitis in humans. They are maintained and transmitted in nature by mosquitoes to preferred vertebrate amplifying hosts. The G2 envelope glycoprotein of La Crosse virus (LAC) was proposed by Ludwig et al. to be a determinant for virus att...

journal_title：Viral immunology

authors： Cheng LL,Schultz KT,Yuill TM,Israel BA

更新日期：2000-01-01 00:00:00

abstract：:The purpose of the study was to evaluate pathologically the reproductive system of nonvaccinated and porcine reproductive and respiratory syndrome virus (PRRSV)-vaccinated sows/gilts, as well as the assessment of vaccination impact on their endometrium/myometrium and ovaries. In a farrow-to-finish farm, all sows and g...

journal_title：Viral immunology

authors： Papatsiros V,Psalla D,Papaioannou D,Tassis P,Tzika E,Papaioannou N

更新日期：2015-05-01 00:00:00

abstract：:Serial virus specimens rescued from rabbits, experimentally infected with bovine immunodeficiency (BIV) strain R29, were monitored for changes in quasispecies population, using the single-strand conformation polymorphism (SSCP) analysis. The generation of characteristic SSCP patterns enables the rapid differentiation ...

journal_title：Viral immunology

authors： Kalvatchev Z,Walder R,Garzaro D,Barrios M

更新日期：2000-01-01 00:00:00

abstract：:Herpesviruses are widely disseminated in the population and establish lifelong latency, which is associated with a variety of pathological consequences. A recent report showed that mice latently infected with either murine gamma-herpesvirus-68 (gammaHV68) or murine cytomegalovirus (mCMV), mouse pathogens genetically s...

journal_title：Viral immunology

authors： Yager EJ,Szaba FM,Kummer LW,Lanzer KG,Burkum CE,Smiley ST,Blackman MA

更新日期：2009-02-01 00:00:00

abstract：:Naïve CD8(+) T cells differentiate into effectors secreting various cytokines that modulate immune functions. A striking finding for most HIV-1-infected patients is that they accumulate CD8(+) T cells belonging to early and intermediate differentiated elements. Structural HIV-1 proteins, and among these the matrix pro...

journal_title：Viral immunology

authors： Avolio M,Caracciolo S,Tosti G,Vollero L,Fiorentini S,Caruso A

更新日期：2008-06-01 00:00:00

abstract：:A paresis isolate of equid herpesvirus 1 (EHV1, Ab4/8) and a plaque-purified virus derived from it (EHV1, Ab4/13), induced long-term suppression of both mitogenic and antigen-specific lymphocyte proliferations in adult outbred ponies. Peripheral blood mononuclear cells (PBMC) taken from a pony after EHV1 infection sup...

journal_title：Viral immunology

authors： Hannant D,O'Neill T,Ostlund EN,Kydd JH,Hopkin PJ,Mumford JA

更新日期：1999-01-01 00:00:00

abstract：:Although field studies have found porcine reproductive and respiratory syndrome (PRRSV) inactivated vaccines to be beneficial in reducing losses linked to PRRSV infection, immune mechanisms induced by these vaccines need better understanding. In the study reported here, we examined the interferon-gamma(+) (IFNgamma(+)...

journal_title：Viral immunology

authors： Piras F,Bollard S,Laval F,Joisel F,Reynaud G,Charreyre C,Andreoni C,Juillard V

更新日期：2005-01-01 00:00:00

abstract：:Outbreaks of the highly pathogenic H5N1 virus in poultry and humans are ongoing. Vaccination is an efficient method for prevention of H5N1 infection. Using chickens and ducks, we assessed the efficacy of a vaccine comprising H5N1 hemagglutinin (HA) protein produced in a baculovirus expression system. The immunized chi...

journal_title：Viral immunology

authors： Park EH,Song BM,Yum J,Kim JA,Oh SK,Kim HS,Cho GJ,Seo SH

更新日期：2014-11-01 00:00:00

abstract：:The present study describes an approach to the development and use of anti-idiotypic antibodies as a possible immunization strategy to prevent retroviral infection. The rationale for using anti-idiotypes (anti-Ids) to try to elicit an antigenic-specific immune response is examined, and the production and characterizat...

journal_title：Viral immunology

authors： Tavares L,Roneker C,Postie L,Fevereiro M,de Noronha F

更新日期：1991-04-01 00:00:00

abstract：:Today, hepatitis C virus (HCV) infection is considered as one of the most significant international health concerns. Although novel therapeutic regimens against the infection have shown satisfactory results, no approved vaccine exists yet. This study aimed to evaluate the immunogenicity of a DNA vaccine candidate for ...

journal_title：Viral immunology

authors： Behzadi MA,Alborzi A,Kalani M,Pouladfar G,Dianatpour M,Ziyaeyan M

更新日期：2016-04-01 00:00:00

abstract：:The VP1 represents the major capsid protein of the hamster polyomavirus (HaPV). Here we describe the mapping of epitopes along the VP1 using Escherichia coli-expressed VP1-dihydrofolate reductase (DHFR) fusion proteins and PepScan analysis. By use of DHFR fusion proteins an immunodominant region was localized in the C...

journal_title：Viral immunology

authors： Siray H,Frömmel C,Voronkova T,Hahn S,Arnold W,Schneider-Mergener J,Scherneck S,Ulrich R

更新日期：2000-01-01 00:00:00

abstract：:Altered T cell profiles have been linked with metrics of persistent cytomegalovirus (CMV) infections in healthy aging and older HIV patients stable on antiretroviral therapy (ART). In this study, we use CMV DNA to identify active infections, and levels of CMV-reactive antibody to assess the persistent burden of CMV in...

journal_title：Viral immunology

authors： Ariyanto IA,Estiasari R,Waters S,Wulandari EAT,Fernandez S,Lee S,Price P

更新日期：2018-07-01 00:00:00

abstract：:The involvement of retroviruses in the etiopathogenesis of autoimmunity is discussed. Recently antibodies against p24 of HIV-1 were described in patients from Texas with SLE. Therefore we investigated the presence of these antibodies in our SLE collective (German caucasians and blacks from Michigan) employing ELISA an...

journal_title：Viral immunology

authors： Herrmann M,Baur A,Nebel-Schickel H,Vornhagen R,Jahn G,Krapf FE,Kalden JR

更新日期：1992-10-01 00:00:00

abstract：:Highly immunogenic ("xenogenized") tumor variants appear after treatment of murine lymphoma L5178Y with the triazene derivative DTIC, this phenomenon being associated with the appearance of structurally abnormal gp70 env proteins in the cell variants. In the present study, we have isolated and sequenced several PCR-am...

journal_title：Viral immunology

authors： Grohmann U,Belladonna ML,Allegrucci M,Silla S,Schiaffella E,Fioretti MC,Puccetti P

更新日期：1994-01-01 00:00:00

abstract：:Porcine reproductive and respiratory syndrome virus (PRRSV) continues to be an economically important infectious disease of swine. Mechanisms governing activation of the innate immune response to PRRSV remain to be elucidated. Virulence differences observed between PRRSV isolates have been attributed to replication ab...

journal_title：Viral immunology

authors： Loving CL,Brockmeier SL,Vincent AL,Lager KM,Sacco RE

更新日期：2008-09-01 00:00:00

abstract：:HIV-1 p17 is a viral cytokine that acts on preactivated, but not on resting, human T cells promoting proliferation, proinflammatory cytokines release and HIV-1 replication, after binding to a cellular receptor (p17R). Here, we demonstrate that p17Rs are expressed on activated murine T cells, which respond to p17 stimu...

journal_title：Viral immunology

authors： Fiorentini S,Becker PD,Marini E,Marconi P,Avolio M,Tosti G,Link C,Manservigi R,Guzman CA,Caruso A

更新日期：2006-07-01 00:00:00

abstract：:Bacterial flagellin is a potent adjuvant that enhances adaptive immune responses to a variety of protein antigens. The vaccinia virus antigens L1R and B5R are highly immunogenic in the context of the parent virus, but recombinant forms of the proteins are only weakly immunogenic. Therefore we evaluated the humoral res...

journal_title：Viral immunology

authors： Delaney KN,Phipps JP,Johnson JB,Mizel SB

更新日期：2010-04-01 00:00:00

abstract：:Unlike the polymorphic MHC class Ia molecules, MHC class Ib molecules are oligomorphic or nonpolymorphic. We recently discovered a protective CD8 T cell response to mouse polyomavirus (MPyV) in H-2(b) haplotype mice that is restricted by H2-Q9, a member of the Qa-2 MHC class Ib family. Here, we demonstrate that immuni...

journal_title：Viral immunology

authors： Hofstetter AR,Evavold BD,Lukacher AE

更新日期：2013-02-01 00:00:00

abstract：:In general, virus-specific antibodies are considered antiviral and play an important role in the control of virus infections in a number of ways. However, in some instances, the presence of specific antibodies can be beneficial to the virus. This activity is known as antibody-dependent enhancement (ADE) of virus infec...

journal_title：Viral immunology

authors： Tirado SM,Yoon KJ

更新日期：2003-01-01 00:00:00

abstract：:Natural killer (NK) cells have been suggested to play a protective role in HIV disease progression. One potent effector mechanism of NK cells is antibody-dependent cellular cytotoxicity (ADCC) mediated by antiviral antibodies binding to the FcγRIIIa receptor (CD16) on NK cells. We investigated NK cell-mediated ADCC fu...

journal_title：Viral immunology

authors： Johansson SE,Rollman E,Chung AW,Center RJ,Hejdeman B,Stratov I,Hinkula J,Wahren B,Kärre K,Kent SJ,Berg L

更新日期：2011-10-01 00:00:00

abstract：:Chemokine receptors CXCR4 and CCR5 play a key role in Human Immunodeficiency Virus (HIV) entry into CD4+ monocytic cells. Alteration in the expression levels of these receptors by immunoregulatory cytokines may influence viral entry and hence susceptibility to HIV infection, viral tropism, and disease progression. Hel...

journal_title：Viral immunology

authors： Creery D,Weiss W,Graziani-Bowering G,Kumar R,Aziz Z,Angel JB,Kumar A

更新日期：2006-07-01 00:00:00

abstract：:Synthetic oligodeoxynucleotides (ODNs) such as CpG can stimulate B and plasmacytoid dendritic cells in vertebrate immune systems. Several studies showed that non-CpG ODNs could also induce strong stimulation of B and T cells. PyNTTTTGT ODNs, non-CpG ODNs, can activate and cause immunoglobulin secretion by B cells and ...

journal_title：Viral immunology

authors： Zhao G,Jin H,Li J,Su B,Du X,Kang Y,Wang X,Wang B

更新日期：2009-04-01 00:00:00

abstract：:Human papillomavirus (HPV) regulation of host immune response leads to cervical lesions. In particular, natural killer (NK) cells are crucial for HPV control. Since specific HLA-I/KIR interactions modify NK cell activation, we analyzed HLA-C and KIR alleles in HPV infection and lesion development in 150 controls, 33 c...

journal_title：Viral immunology

authors： Rizzo R,Gentili V,Rotola A,Bortolotti D,Cassai E,Di Luca D

更新日期：2014-11-01 00:00:00

abstract：:One of the most profound enigmas in B cell biology is how activation-induced deaminase (AID) is targeted to a very small region of DNA in the immunoglobulin loci. Two specific regions are singled out: the variable region of 2 kb that contains rearranged genes on the heavy, κ light, and λ light chain loci, and the swit...

journal_title：Viral immunology

authors： Heltzel JMH,Gearhart PJ

更新日期：2020-05-01 00:00:00