Safety of nitrous oxide administration in patients with Charcot-Marie-Tooth disease.

abstract：:Morphologic alterations in biopsies of central and peripheral nervous tissue were investigated at the light-and electron-microscopic level in the first cases of lysosomal alpha-N-acetylgalactosaminidase deficiency. Widespread spheroid formation was observed in terminal and preterminal axons. Neocortical and peripheral...

journal_title：Journal of the neurological sciences

authors： Wolfe DE,Schindler D,Desnick RJ

更新日期：1995-09-01 00:00:00

abstract：:Epidemiologists have found a decreased risk of developing Alzheimer's disease (AD) in people taking statins (cholesterol biosynthesis inhibitors). We have reported previously that, in cell culture, lovastatin decreases the output of beta-amyloid, a peptide that is toxic to neurones, and is reputably the prime cause of...

journal_title：Journal of the neurological sciences

authors： Sidera C,Parsons R,Austen B

更新日期：2005-03-15 00:00:00

abstract：:We report median and digital nerve somatosensory evoked potentials (SEPs) in 14 patients with probable progressive supranuclear palsy (PSP) along with transcortical long-loop reflexes, motor evoked potentials, and auditory startle responses. Enlarged cortical responses were found in 14 median and 13 digital nerve SEP ...

journal_title：Journal of the neurological sciences

authors： Kofler M,Müller J,Reggiani L,Wenning GK

更新日期：2000-10-01 00:00:00

abstract：:A method is described which characterises the conduction deficit of a nerve in terms of the distribution of the refractory periods of transmission (RPTs) of its constituent fibres. The RPT is a particularly sensitive index of conduction deficit and measures the ability of a nerve fibre to conduct pairs of closely spac...

journal_title：Journal of the neurological sciences

authors： Smith KJ

更新日期：1980-11-01 00:00:00

abstract：:The retrovirus that causes the acquired immunodeficiency syndrome (AIDS) has two targets: the immune system and the nervous system. Central nervous system (CNS) manifestations of AIDS are protean. This review describes the opportunistic infections and malignancies that affect the nervous system in AIDS, and discusses ...

journal_title：Journal of the neurological sciences

authors： Tucker T

更新日期：1989-02-01 00:00:00

abstract：:The purpose of this paper is to systematically review the literature on the use of near-infrared spectroscopy (NIRS) for assessing spasticity. MEDLINE, CINAHL, and EMBASE were searched for human and/or animal studies written in the English language published until November 2018. that used NIRS to examine the hemodynam...

journal_title：Journal of the neurological sciences

authors： McDougall J,Chow E,Harris RL,Mills PB

更新日期：2020-05-15 00:00:00

abstract：:We report on a four-year-old girl with head trauma caused by a motor vehicle accident. She presented with delirium, oculomotor palsy and ptosis in her left eye, left hemiparesis, and pyramidal signs in all extremities. Computed tomography on the day of admission showed diffuse cerebral edema with right-sided predomina...

journal_title：Journal of the neurological sciences

authors： Okanishi T,Saito Y,Fujii S,Maegaki Y,Fukuda C,Tomita Y,Ohno K

更新日期：2007-12-15 00:00:00

abstract：:Friedreich Ataxia (FRDA) is an autosomal recessive neurodegenerative disorder most commonly caused by guanine-adenine-adenine (GAA) trinucleotide repeat expansions in both alleles of the FXN gene. Although progressive ataxia remains the hallmark clinical feature, patients with FRDA are at high risk of developing cardi...

journal_title：Journal of the neurological sciences

authors： McCormick A,Shinnick J,Schadt K,Rodriguez R,Addonizio L,Hirano M,Perlman S,Lin KY,Lynch DR

更新日期：2017-04-15 00:00:00

abstract：:An X-linked myopathy was recently associated with mutations in the four-and-a-half-LIM domains 1 (FHL1) gene. We identified a family with late onset, slowly progressive weakness of scapuloperoneal muscles in three brothers and their mother. A novel missense mutation in the LIM2 domain of FHL1 (W122C) co-segregated wit...

journal_title：Journal of the neurological sciences

authors： Chen DH,Raskind WH,Parson WW,Sonnen JA,Vu T,Zheng Y,Matsushita M,Wolff J,Lipe H,Bird TD

更新日期：2010-09-15 00:00:00

abstract：:Despite apparent relationships between ischemic stroke and the acute phase response (APR), considerable variation in the APR exists between individuals. We therefore performed post-hoc analysis of individual APR profiles in 31 patients with ischemic stroke in relation to volume of brain infarction. Patients with ische...

journal_title：Journal of the neurological sciences

authors： Smith CJ,Emsley HC,Vail A,Georgiou RF,Rothwell NJ,Tyrrell PJ,Hopkins SJ

更新日期：2006-12-21 00:00:00

abstract：:Degeneration at the neuromuscular function following cutting the phrenic nerve at the 9th intercostal space differs in red, white and intermediate skeletal muscle fibers. The ultrastructure of the nerve terminal and the muscle fiber between 12 hours and 21 days following denervation suggests that lack of neurotrophic ...

journal_title：Journal of the neurological sciences

authors： Pulliam DL,April EW

更新日期：1979-10-01 00:00:00

abstract：:Long-term effects of MPTP on striatal dopamine (DA) content and the influence of aging on the recovery were investigated in mice. Male C57BL/6J mice, young (2-month-old) and mature (10-month-old), were used. Two different dosage schedules of MPTP, i.e., 4 doses subcutaneous injections of 20 mg/kg each, and 4 doses sub...

journal_title：Journal of the neurological sciences

authors： Saitoh T,Niijima K,Mizuno Y

更新日期：1987-02-01 00:00:00

abstract：:We assessed neuropsychological performances of 22 patients affected by Autosomal Dominant Cerebellar Ataxia type 1. All subjects completed a comprehensive battery of standardized tests requiring a verbal response, without time constraints. In order to verify the hypothesis that disease severity is the major factor in ...

journal_title：Journal of the neurological sciences

authors： Trojano L,Chiacchio L,Grossi D,Pisacreta AI,Calabrese O,Castaldo I,De Michele G,Filla A

更新日期：1998-05-07 00:00:00

abstract：:Further observations on a family with facioscapulohumeral (FSH) muscular dystrophy due to mitochondrial myopathy, and on a case with lipid storage myopathy are reported. One member of the family with FSH muscular dystrophy died due to a viral pneumonia, during which she developed gross hyperlacticacidaemia and acidosi...

journal_title：Journal of the neurological sciences

authors： Bradley WG,Tomlinson BE,Hardy M

更新日期：1978-02-01 00:00:00

abstract：:We present a patient with Parkinson's disease whose bilateral tremor transiently resolved after a unilateral left ventrolateral thalamotomy. The transient resolution of the bilateral tremor was associated with a focal thalamic lesion and a second lesion in the corpus callosum. The mechanism of this phenomenon may be r...

journal_title：Journal of the neurological sciences

authors： Greene KA,Wallace RC,Fram EK,Shetter AG,Lieberman AN

更新日期：1995-03-01 00:00:00

abstract：:We performed a population based survival analysis of all incident cases (220) of motor neuron disease (MND) in the province of Turin, Italy, during the period 1966-1980. 175 cases were diagnosed as amyotrophic lateral sclerosis (ALS), 43 as progressive muscular atrophy (PMA) and 2 as progressive bulbar palsy (PBP). Th...

journal_title：Journal of the neurological sciences

authors： Mortara P,Chiò A,Rosso MG,Leone M,Schiffer D

更新日期：1984-11-01 00:00:00

abstract：:A single micro-injection of Tumour Necrosis Factor alpha (TNF) or gamma Interferon (IFN-gamma) into the lumbosacral spinal cord of the rat produced meningitis and mononuclear cuffs within the cord, an inflammatory response remarkably similar in pattern to that observed during experimental autoimmune encephalomyelitis ...

journal_title：Journal of the neurological sciences

authors： Simmons RD,Willenborg DO

更新日期：1990-12-01 00:00:00

abstract：:To clarify the current status of treatments and outcomes of patients with myasthenia gravis (MG) in Japan, a total of 470 patients (164 men and 306 women; mean age 41 years) were recruited from 19 Japanese tertiary medical centers in 1999-2000. Thymectomy was performed in 319 (68%) of the patients. Patients who receiv...

journal_title：Journal of the neurological sciences

authors： Kawaguchi N,Kuwabara S,Nemoto Y,Fukutake T,Satomura Y,Arimura K,Osame M,Hattori T,Study Group for Myasthenia Gravis in Japan.

更新日期：2004-09-15 00:00:00

abstract：:To improve the understanding of neuronal cell swelling in cerebral ischemia, cell volume regulation, viability, intracellular electrolytes, and lactate production of Neuro-2A neuroblastoma cells were studied using an in vitro model. The volume regulatory capacity of Neuro-2A cells was assessed after incubation in hypo...

journal_title：Journal of the neurological sciences

authors： Mackert BM,Staub F,Peters J,Baethmann A,Kempski O

更新日期：1996-07-01 00:00:00

abstract：:Out of 66 patients who were diagnosed as suffering from polymyalgia rheumatica (PMR; n = 40), temporal arteritis (AT; n = 14) or both (n = 12) in a 6.5 year period (incidence 3.4/100,000 per year), 9 died and 49 were followed up for an average period of 28 months. Exacerbations of the illness (n = 24) and complication...

journal_title：Journal of the neurological sciences

authors： Berlit P

更新日期：1992-08-01 00:00:00

abstract：OBJECTIVES:We hypothesize that the regional pattern of blood flow reduction in the brain is different between tremor-dominant Parkinson's disease (PD) and postural instability gait difficulty (PIGD)-dominant PD. We therefore investigated the association of phenotypes in untreated PD with brain perfusion on SPECT using ...

journal_title：Journal of the neurological sciences

authors： Mito Y,Yoshida K,Yabe I,Makino K,Tashiro K,Kikuchi S,Sasaki H

更新日期：2006-02-15 00:00:00

abstract：:We have evaluated cortical excitability in nine patients affected by Wilson's disease (WD) using transcranial magnetic (TMS) and electric (TES) cortical stimulation and central silent period (CSP) data. A clinical score was derived from the sum of scores assigned to extrapyramidal, pyramidal and cerebellar signs. All ...

journal_title：Journal of the neurological sciences

authors： Perretti A,Pellecchia MT,Lanzillo B,Campanella G,Santoro L

更新日期：2001-11-15 00:00:00

abstract：:We report the case of a woman with primary progressive aphasia (PPA) presenting with conduction aphasia. Neurological findings showed bilateral finger tremor and signe de poignet figé in her right hand. Memory, orientation, and activities of daily living were well preserved. Linguistic examination showed severe impair...

journal_title：Journal of the neurological sciences

authors： Kimura N,Kumamoto T,Hanaoka T,Hazama Y,Nakamura K,Arakawa R

更新日期：2008-06-15 00:00:00

abstract：:Dementia of the Alzheimer type (DAT) and vascular dementia (VaD) are the two major subtypes of dementia. In our epidemiological study of DAT in an Arab community in Wadi Ara, Israel, we found a high prevalence of late onset DAT. Illiteracy, smoking, diabetes mellitus (DM) and hypertension are very frequent in Wadi Ara...

journal_title：Journal of the neurological sciences

authors： Bowirrat A,Friedland RP,Korczyn AD

更新日期：2002-11-15 00:00:00

abstract：:Vascular dementia (VaD) is increasingly recognised to reflect an outmoded concept in that it identifies cases too late for preventive therapy to have an opportunity to prevent the development of dementia and uses a cognitive paradigm inappropriately based on Alzheimer's disease. A replacement is urgently required and ...

journal_title：Journal of the neurological sciences

authors： Bowler JV

更新日期：2002-11-15 00:00:00

abstract：:The interictal hypometabolism in patients with focal epilepsy is usually regarded as stationary. In this study we investigated to which extent the hypometabolism may depend on the activity of the epileptic focus. In focal penicillin-induced epilepsy in rats the epileptic focus is hypermetabolic. This focus is accompan...

journal_title：Journal of the neurological sciences

authors： Witte OW,Bruehl C,Schlaug G,Tuxhorn I,Lahl R,Villagran R,Seitz RJ

更新日期：1994-07-01 00:00:00

abstract：:Stroke is a leading cause of global morbidity and mortality. Sub-Saharan Africa (SSA), where an unprecedented rise in stroke burden is currently raging, has the highest age-standardized stroke incidence, stroke prevalence, and stroke mortality rates. This is in sharp contrast to the relative decline in stroke incidenc...

journal_title：Journal of the neurological sciences

authors： Owolabi M,Sarfo FS,Akinyemi R,Gebreyohanns M,Ovbiagele B

更新日期：2019-05-15 00:00:00

abstract：INTRODUCTION:Palinacousis is a paroxysmal auditory illusion in which perseveration of an external auditory stimulus occurs after cessation of the stimulus. The subjects recognize the illusory nature of this experience, which is often a fragment of the last sentence they heard. Palinacousis has been reported in only a f...

journal_title：Journal of the neurological sciences

authors： Mohamed W,Ahuja N,Shah A

更新日期：2012-06-15 00:00:00

abstract：:An epidemic of subacute bilateral visual failure has affected large numbers of teenagers and young adult Africans in coastal Tanzania since 1988. Previous work had indicated that many patients had sensory symptoms, but the nature of the neurological involvement was uncertain. The primary objective of this study was to...

journal_title：Journal of the neurological sciences

authors： Plant GT,Mtanda AT,Arden GB,Johnson GJ

更新日期：1997-02-12 00:00:00

abstract：:The aim of this study was to determine the effectiveness of hypoglossal-facial nerve "side"-to-end (HemiHN-FN) and accessory-facial nerve end-to-end (AN-FN) neurorrhaphy using a predegenerated nerve graft (PNG) for reanimating facial paralysis in a rat FN injury model. A total of 25 rats with complete unilateral facia...

journal_title：Journal of the neurological sciences

authors： Li D,Wan H,Feng J,Wang S,Su D,Hao S,Schumacher M,Liu S

更新日期：2014-12-15 00:00:00