Biological stress responses in high and low trait anxious students.

Abstract:

:In an investigation of biological indicators of stress in normal humans, undergraduate psychology students were differentiated on trait anxiety and assessed under baseline, preexam (stress), and postexam conditions. Assessment at each condition involved drawing 20 ml of blood, followed by self-reporting for selected questionnaires. Self-reports included state anxiety, general psychological symptomatology, dysfunctional attitudes, academic confidence, sleep patterns, and intake of drugs, including alcohol and caffeine. Blood was analyzed for whole blood serotonin content, plasma MHPG, and platelet imipramine binding. Baseline differences between high and low trait anxious students on biological measures were significant only for whole blood serotonin content. Variation across situational conditions was significant for whole blood serotonin, with an increase under the stressful condition for both anxiety groups. Thus, serotonin is highlighted as an important factor in the human response to stress, whereas expected differences in MHPG were not observed. The serotonergic response to stress was not explained by changes in psychological or physical state variables. Changes in serotonin content were positively correlated with changes in platelet imipramine binding.

journal_name

Biol Psychiatry

journal_title

Biological psychiatry

authors

Davis DD,Dunlop SR,Shea P,Brittain H,Hendrie HC

doi

10.1016/0006-3223(85)90209-4

subject

Has Abstract

pub_date

1985-08-01 00:00:00

pages

843-51

issue

8

eissn

0006-3223

issn

1873-2402

pii

0006-3223(85)90209-4

journal_volume

20

pub_type

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