当前位置： SCI文献检索 > BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS期刊下所有文献 > Inhibitory effects of selenium on the growth of DU-145 human prostate carcinoma cells in vitro.

Inhibitory effects of selenium on the growth of DU-145 human prostate carcinoma cells in vitro.

Abstract：

:The growth of DU-145 human prostate carcinoma cells is reduced to 50% of control by 1 X 10(-6) M to 2 X 10(-6) M selenium and to 2% of control at 10(-4)M selenium. These cells show greater sensitivity to inhibition of growth or DNA synthesis by selenium than human W1-38 and HeLa cells and mouse mammary tumor cells. It has been shown that selenium inhibits carcinogenesis and reduces the incidence of chemical carcinogen and virus-induced tumors of a variety of organs in animals. Selenium may also inhibit the growth of certain tumor cells of non-human origin. To our knowledge, this is the first study on the effects of selenium on the growth of human tumor cells. From extrapolation, it is deduced that selenium serum levels in humans living in high selenium areas may be as high as 10(-6) M and could be effective in inhibiting the growth of tumor cells in vivo. These findings have implications in the prevention and intervention of prostate cancer in man.

journal_name

Biochem Biophys Res Commun

journal_title

Biochemical and biophysical research communications

authors

Webber MM,Perez-Ripoll EA,James GT

doi

10.1016/0006-291x(85)90459-0

subject

Has Abstract

pub_date

1985-07-31 00:00:00

pages

603-9

issue

2

eissn

0006-291X

issn

1090-2104

pii

0006-291X(85)90459-0

journal_volume

130

pub_type

杂志文章

相关文献

BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS文献大全
  • Increased cerebrospinal fluid complement C5 levels in major depressive disorder and schizophrenia.

    abstract：:Inflammation has been implicated in a variety of psychiatric disorders. We aimed to determine whether levels of complement C5 protein in the cerebrospinal fluid (CSF), which may reflect activation of the complement system in the brain, are altered in patients with major psychiatric disorders. Additionally, we examined...

    journal_title：Biochemical and biophysical research communications

    pub_type： 杂志文章

    doi：10.1016/j.bbrc.2018.02.131

    authors： Ishii T,Hattori K,Miyakawa T,Watanabe K,Hidese S,Sasayama D,Ota M,Teraishi T,Hori H,Yoshida S,Nunomura A,Nakagome K,Kunugi H

    更新日期：2018-03-04 00:00:00

  • DNA methylation status influences insulin-induced glucose transport in 3T3-L1 adipocytes by mediating p53 expression.

    abstract：:Researchers frequently use 3T3-L1 adipocytes as a fat cell line, but the capacity of this line for insulin-mediated glucose transport is lower than that of primary isolated fat cells. In this study, we found that 5-azacytidine (5-aza-C), DNA methyltransferase 1 inhibitor, enhanced insulin-stimulated 2-deoxyglucose (2-...

    journal_title：Biochemical and biophysical research communications

    pub_type： 杂志文章

    doi：10.1016/j.bbrc.2020.02.038

    authors： Kuroda M,Onoyama R,Sasaki W,Sebe M,Kitamura T,Masumoto S,Tsutsumi R,Harada N,Sakaue H

    更新日期：2020-02-16 00:00:00

  • Effect of fish oils on rat plasma lipoproteins.

    abstract：:Plasma high (HDL) and low (LDL) density lipoproteins were isolated from rats fed a diet supplemented with either fish (menhaden) oil or hydrogenated coconut oil (control). Fluorescence polarization and electron spin resonance of labelled fatty acid probe molecules incorporated into the outer amphiphilic monolayer of H...

    journal_title：Biochemical and biophysical research communications

    pub_type： 杂志文章

    doi：10.1016/0006-291x(88)90737-1

    authors： Belcher D,Stillwell W,Langsford CA,Wassall SR

    更新日期：1988-02-15 00:00:00

  • Measurement of nitric oxide release in the isolated perfused rat lung.

    abstract：:In this study we have continuously measured real-time production of nitric oxide (NO) in the isolated, perfused rat lung by using an NO monitor (model NO-501, Inter Medical Co., Nagoya, Japan) with an NO-selective resin microsensor. A stable NO response was obtained when the sensor was placed in the pulmonary artery o...

    journal_title：Biochemical and biophysical research communications

    pub_type： 杂志文章

    doi：10.1006/bbrc.1995.1435

    authors： Wang D,Hsu K,Hwang CP,Chen HI

    更新日期：1995-03-28 00:00:00

  • Identification of a sphingosine-sensitive Ca2+ channel in the plasma membrane of Leishmania mexicana.

    abstract：:The disruption of the intracellular Ca(2+) homeostasis of Leishmania mexicana represents a major target for the action of drugs, such as amiodarone and miltefosine. However, little is known about the mechanism of Ca(2+) entry to these cells. Here we show the presence of a Ca(2+) channel in the plasma membrane of these...

    journal_title：Biochemical and biophysical research communications

    pub_type： 杂志文章

    doi：10.1016/j.bbrc.2012.12.033

    authors： Benaim G,García-Marchán Y,Reyes C,Uzcanga G,Figarella K

    更新日期：2013-01-18 00:00:00

  • Leucine-rich repeat-containing G-protein coupled receptor 5 enriched organoids under chemically-defined growth conditions.

    abstract：:An organoid is a complex, multi-cell three-dimensional (3D) structure that contains tissue-specific cells. Epithelial stem cells, which are marked by leucine-rich repeat-containing G-protein coupled receptor 5 (Lgr5), have the potential for self-renewal and expansion as organoids. However, in the case of intestinal or...

    journal_title：Biochemical and biophysical research communications

    pub_type： 杂志文章

    doi：10.1016/j.bbrc.2018.11.003

    authors： Hahn S,Kim MS,Choi SY,Jeong S,Jee J,Kim HK,Jeong SY,Shin H,Kim HS,Park JS,Yoo J

    更新日期：2019-01-08 00:00:00

  • Activation of AMP-activated protein kinase by compound 991 protects osteoblasts from dexamethasone.

    abstract：:Dexamethasone (Dex) induces direct cytotoxicity to cultured osteoblasts. The benzimidazole derivative compound 991 ("C991") is a novel and highly-efficient AMP-activated protein kinase (AMPK) activator. Here, in both MC3T3-E1 osteoblastic cells and primary murine osteoblasts, treatment with C991 activated AMPK signali...

    journal_title：Biochemical and biophysical research communications

    pub_type： 杂志文章

    doi：10.1016/j.bbrc.2017.11.132

    authors： Xu YY,Chen FL,Ji F,Fei HD,Xie Y,Wang SG

    更新日期：2018-01-01 00:00:00

  • Regulation of adiponectin receptor R1 and R2 gene expression in adipocytes of C57BL/6 mice.

    abstract：:Adiponectin has gained significant attention as a mediator of insulin sensitivity. Recently, two receptors of this adipocyte-secreted hormone, adiponectin receptor 1 (AdipoR1) and 2 (AdipoR2), have been cloned. To improve our understanding of the regulation of these receptors in adipocytes, AdipoR1 and AdipoR2 mRNA wa...

    journal_title：Biochemical and biophysical research communications

    pub_type： 杂志文章

    doi：10.1016/j.bbrc.2005.02.081

    authors： Blüher M,Fasshauer M,Kralisch S,Schön MR,Krohn K,Paschke R

    更新日期：2005-04-15 00:00:00

  • Antibiotics-induced gut microbiota dysbiosis promotes tumor initiation via affecting APC-Th1 development in mice.

    abstract：:Gut microbiota is critical for maintaining body immune homeostasis and thus affects tumor growth and therapeutic efficiency. Here, we investigated the link between microbiota and tumorgenesis in a mice model of subcutaneous melanoma cell transplantation, and explored the underlying mechanism. We found disruption of gu...

    journal_title：Biochemical and biophysical research communications

    pub_type： 杂志文章

    doi：10.1016/j.bbrc.2017.05.071

    authors： Xu C,Ruan B,Jiang Y,Xue T,Wang Z,Lu H,Wei M,Wang S,Ye Z,Zhai D,Wang L,Lu Z

    更新日期：2017-06-24 00:00:00

  • Ser-261 phospho-regulation is involved in pS256 and pS269-mediated aquaporin-2 apical translocation.

    abstract：:Vasopressin catalyzes aquaporin-2 phosphorylation at several serine sites in the C-terminal region. Compared with Ser-256 and Ser-269 phosphorylation, the role of Ser-261 phospho-regulation on vasopressin-regulated AQP2 apical translocation is largely unknown. In addition, recent discovery of transcytotic apical deliv...

    journal_title：Biochemical and biophysical research communications

    pub_type： 杂志文章

    doi：10.1016/j.bbrc.2017.06.162

    authors： Yui N,Ando F,Sasaki S,Uchida S

    更新日期：2017-08-26 00:00:00

  • The presence of free D-aspartic acid in rodents and man.

    abstract：:Free D-aspartic acid is present in appreciable quantities in the brain and other tissues of rodents and in human blood. In the newborn rat, the highest concentration of D-aspartic acid was found in cerebral hemispheres, where, at 164 nmol/g (8.4% of the total aspartic acid), the level of D-aspartic acid exceeds that o...

    journal_title：Biochemical and biophysical research communications

    pub_type： 杂志文章

    doi：10.1016/s0006-291x(86)80329-1

    authors： Dunlop DS,Neidle A,McHale D,Dunlop DM,Lajtha A

    更新日期：1986-11-26 00:00:00

  • beta2-Integrin and lipid modifications indicate a non-antioxidant mechanism for the anti-atherogenic effect of dietary coenzyme Q10.

    abstract：:Dietary supplementation with coenzyme Q (CoQ) has been proposed to have anti-atherogenic effects by virtue of its antioxidant capacity. To investigate this question, the leukocyte status of 5 males and 5 females (52-68 years) was evaluated before and after supplementation with 200mg CoQ/day for 5 and 10 weeks. CoQ was...

    journal_title：Biochemical and biophysical research communications

    pub_type： 杂志文章

    doi：10.1016/s0006-291x(02)00871-9

    authors： Turunen M,Wehlin L,Sjöberg M,Lundahl J,Dallner G,Brismar K,Sindelar PJ

    更新日期：2002-08-16 00:00:00

  • Classification and interaction modes of 40 rice E2 ubiquitin-conjugating enzymes with 17 rice ARM-U-box E3 ubiquitin ligases.

    abstract：:Rice, a monocot model crop, contains at least 48 putative E2 ubiquitin (Ub)-conjugating enzymes. Based on homology comparisons with 40 Arabidopsis E2 proteins and 35 human E2s, 48 rice E2s were classified into 15 different groups. Yeast two-hybrid analyses using the U-box-domain regions of armadillo (ARM)-U-box E3 Ub-...

    journal_title：Biochemical and biophysical research communications

    pub_type： 杂志文章

    doi：10.1016/j.bbrc.2014.01.098

    authors： Bae H,Kim WT

    更新日期：2014-02-21 00:00:00

  • Formation of N-nitrosodiphenylamine from 1,1-diphenylhydrazine by rat liver microsomal preparations.

    abstract：:The present study provides the first evidence for in vitro metabolic conversion of a 1,1-disubstituted hydrazine to the corresponding nitrosamine. The study shows that superoxide radical which is generated by NADPH-cytochrome c reductase is involved in the oxidation of 1,1-diphenylhydrazine to N-nitrosodiphenylamine c...

    journal_title：Biochemical and biophysical research communications

    pub_type： 杂志文章

    doi：10.1016/0006-291x(84)91488-8

    authors： Tatsumi K,Kitamura S,Sumida M

    更新日期：1984-02-14 00:00:00

  • Protein kinase C phosphorylates both the light chains and the head portion of the heavy chains of brain myosin.

    abstract：:Protein kinase C phosphorylated both the 19/21-kDa regulatory light chains and heavy chains of bovine brain myosin. The major phosphorylation sites of the light chains were on their threonyl residues, while those for myosin light chain kinase were on their seryl residues. Whereas several non-muscle regular myosins hav...

    journal_title：Biochemical and biophysical research communications

    pub_type： 杂志文章

    doi：10.1016/0006-291x(90)92022-r

    authors： Ikeda N,Yasuda S,Muguruma M,Matsumura S

    更新日期：1990-06-29 00:00:00

  • Structural characteristics of immunogenic liver-stage antigens derived from P. falciparum malarial proteins.

    abstract：:A fully effective antimalarial vaccine must contain multiple proteins from the different development stages of Plasmodium falciparum parasites involved in host-cell invasion or their biologically active fragments. It must therefore include sporozoite molecules able to induce protective immunity by blocking the parasit...

    journal_title：Biochemical and biophysical research communications

    pub_type： 杂志文章

    doi：10.1016/j.bbrc.2009.04.138

    authors： Cifuentes G,Vanegas M,Martinez NL,Pirajan C,Patarroyo ME

    更新日期：2009-07-10 00:00:00

  • Overproduction of the Bradyrhizobium japonicum c-type cytochrome subunits of the cbb3 oxidase in Escherichia coli.

    abstract：:We report on a system to improve expression of mature c-type cytochromes in Escherichia coli. It is based on the use of plasmid pEC86 that expresses the E. coli cytochrome c maturation genes ccmABCDEFGH constitutively, whereby the production of both endogenous and foreign c-type cytochromes was increased substantially...

    journal_title：Biochemical and biophysical research communications

    pub_type： 杂志文章

    doi：10.1006/bbrc.1998.9549

    authors： Arslan E,Schulz H,Zufferey R,Künzler P,Thöny-Meyer L

    更新日期：1998-10-29 00:00:00

  • Structural studies on Allium cepa L. chromatin: enhanced stability of internucleosome interactions in plant chromatin.

    abstract：:The pattern of micrococcal nuclease digestion of chromatin from different organs of Allium cepa has been studied. The DNA from small oligonucleosomes appears to be highly degraded and heterogeneous. In solutions of intermediate ionic strength (0.15 M NaCl) histones H2A and H2B form dimers, however at high salt concent...

    journal_title：Biochemical and biophysical research communications

    pub_type： 杂志文章

    doi：10.1016/0006-291x(85)91940-0

    authors： Moreno ML,Puigdomenech P,Palau J

    更新日期：1985-06-28 00:00:00

  • Macrophage paraoxonase 1 (PON1) binding sites.

    abstract：:Paraoxonase 1 (PON1), an HDL-associated esterase, is known to possess anti-oxidant and anti-atherogenic properties. PON1 was shown to protect macrophages from oxidative stress, to inhibit macrophage cholesterol biosynthesis, and to stimulate HDL-mediated cholesterol efflux from the cells. The aim of the present study ...

    journal_title：Biochemical and biophysical research communications

    pub_type： 杂志文章

    doi：10.1016/j.bbrc.2008.08.106

    authors： Efrat M,Aviram M

    更新日期：2008-11-07 00:00:00

  • Cloning and functional expression of a swelling-induced chloride conductance regulatory protein, plCln, from rabbit ocular ciliary epithelium.

    abstract：:The cDNA encoding a swelling-induced chloride conductance regulatory protein, plcln, was cloned from rabbit ciliary epithelium by using a polymerase chain reaction (PCR)-based approach. The open reading frame encoding 236 amino acids possesses high amino acid identity (93/%) with the previously cloned plcln from human...

    journal_title：Biochemical and biophysical research communications

    pub_type： 杂志文章

    doi：10.1006/bbrc.1997.7523

    authors： Wan XL,Chen S,Sears M

    更新日期：1997-10-29 00:00:00

  • 8-azaguanosine-5'-monophosphate synthesis via nucleoside kinase in cultured Chinese hamster lung fibroblasts.

    abstract：:Cultured chinese hamster lung fibroblasts, and a variant clone selected for resistance to 8-azaguanine, that lacks hypoxanthine-guanine phosphoribosyl transferase (EC 2.4.2.8), have been tested for the ability to convert 8-azaguanine into 8-azaguanosine-5'-monophosphate via purine nucleoside phosphorylase and nucleosi...

    journal_title：Biochemical and biophysical research communications

    pub_type： 杂志文章

    doi：10.1016/0006-291x(89)90073-9

    authors： Tozzi MG,Camici M,Falcone V,Turriani M,Turchi G,Ipata PL

    更新日期：1989-03-15 00:00:00

  • Cloning and characterization of the gene encoding the mouse peptide transporter PEPT2.

    abstract：:Here we describe the cDNA structure, genomic organization, chromosomal localization, and promoter analysis of the mouse peptide transporter PEPT2. The PEPT2-cDNA is 3987 bp long and encodes a protein of 729 amino acids. The functional properties, analyzed by expression in Xenopus laevis oocytes, showed a typical PEPT2...

    journal_title：Biochemical and biophysical research communications

    pub_type： 杂志文章

    doi：10.1006/bbrc.2000.3546

    authors： Rubio-Aliaga I,Boll M,Daniel H

    更新日期：2000-09-24 00:00:00

  • Involvement of syntaxin 4 in the transport of membrane-type 1 matrix metalloproteinase to the plasma membrane in human gastric epithelial cells.

    abstract：:Membrane-type 1 matrix metalloproteinase (MT1-MMP) localized on the plasma membrane plays a central role in various normal biological responses including tissue remodeling, wound heeling, and angiogenesis and in cancer cell invasion and metastasis, by functioning as a collagenase and activating other matrix metallopro...

    journal_title：Biochemical and biophysical research communications

    pub_type： 杂志文章

    doi：10.1016/j.bbrc.2004.08.064

    authors： Miyata T,Ohnishi H,Suzuki J,Yoshikumi Y,Ohno H,Mashima H,Yasuda H,Ishijima T,Osawa H,Satoh K,Sunada K,Kita H,Yamamoto H,Sugano K

    更新日期：2004-10-08 00:00:00

  • Interaction between phosphoinositide turnover system and cyclic AMP pathway for the secretion of pancreastatin and somatostatin from QGP-1N cells.

    abstract：:It is found that secretion of pancreastatin and somatostatin from QGP-1N cells is regulated through muscarinic receptor-mediated activation of phosphatidylinositide hydrolysis system. In this report, whether the cAMP pathway interacts with the phosphoinositide turnover system for the secretion of pancreastatin and som...

    journal_title：Biochemical and biophysical research communications

    pub_type： 杂志文章

    doi：10.1016/0006-291x(92)91731-5

    authors： Tateishi K,Funakoshi A,Kitayama N,Matsuoka Y

    更新日期：1992-06-30 00:00:00

  • Thylakoid-bound chloroplast DNA from spinach is enriched for replication forks.

    abstract：:Chloroplast DNA is bound to the thylakoids of spinach chloroplasts. To examine a possible role for thylakoid-bound DNA in chloroplast DNA replication, vesicles formed by treating chloroplasts in 3.5 mM MgCl2 were used. Chloroplast DNA fragments are bound to the surface of these vesicles. Chloroplast DNA isolated from ...

    journal_title：Biochemical and biophysical research communications

    pub_type： 杂志文章

    doi：10.1016/s0006-291x(05)80194-9

    authors： Lindbeck AG,Rose RJ

    更新日期：1990-10-15 00:00:00

  • Peptide growth factors markedly decrease the ligand binding of angiotensin II type 2 receptor in rat cultured vascular smooth muscle cells.

    abstract：:Of two major isoforms of angiotensin II receptors, AT1 and AT2, biological roles of AT2 remain unclear. Using vascular smooth muscle cells, we investigated the regulation of expression of AT2 by growth factors in comparison with that of AT1. The cultured rat aorta smooth muscle cells had detectable AT2 binding sites, ...

    journal_title：Biochemical and biophysical research communications

    pub_type： 杂志文章

    doi：10.1006/bbrc.1993.1844

    authors： Kambayashi Y,Bardhan S,Inagami T

    更新日期：1993-07-15 00:00:00

  • Dual effect of insulin on in vitro leptin secretion by adipose tissue.

    abstract：:Although it is widely accepted that insulin stimulates leptin secretion, a dual action was observed using a validated in vitro system, i.e., an early (less than 48 h) inhibitory action, followed later (48-96 h) by a clear-cut stimulation. While the inhibitory phase was observed at every glucose concentration tested (f...

    journal_title：Biochemical and biophysical research communications

    pub_type： 杂志文章

    doi：10.1006/bbrc.2000.3506

    authors： Casabiell X,Piñeiro V,De la Cruz LF,Gualillo O,Folgar L,Diéguez C,Casanueva FF

    更新日期：2000-09-24 00:00:00

  • Neonatal pancreatic cells redifferentiate into both neural and pancreatic lineages.

    abstract：:Studies of islet neogenesis have suggested that the regeneration of islet cells can be achieved through redifferentiation of pre-existing islet cells. However, this hypothesis is largely unproven and fails to account for the diversity of observed islet neogenesis. Here we show that cultured neonatal pancreatic cells d...

    journal_title：Biochemical and biophysical research communications

    pub_type： 杂志文章

    doi：10.1016/j.bbrc.2006.10.179

    authors： Zhao W,Hirose T,Ishikawa M,Oshima Y,Hirai S,Ohno S,Taniguchi H

    更新日期：2007-01-05 00:00:00

  • Transcriptional inhibitors affecting topoisomerase II induce changes in histone methylation patterns similar to those induced by heat shock.

    abstract：:The relationship between gene expression and the patterns of histone methylation in Drosophila cells has been investigated using inhibitors of transcription acting at various levels. Inhibition of ribosomal RNA synthesis and processing by 5-fluorouridine or of general RNA synthesis by camptothecin, an inhibitor of top...

    journal_title：Biochemical and biophysical research communications

    pub_type： 杂志文章

    doi：10.1016/0006-291x(89)90778-x

    authors： Desrosiers R,Tanguay RM

    更新日期：1989-08-15 00:00:00

  • Construction of nerve guide conduits from cellulose/soy protein composite membranes combined with Schwann cells and pyrroloquinoline quinone for the repair of peripheral nerve defect.

    abstract：:Regeneration and functional reconstruction of peripheral nerve defects remained a significant clinical challenge. Nerve guide conduits, with seed cells or neurotrophic factors (NTFs), had been widely used to improve the repair and regeneration of injured peripheral nerve. Pyrroloquinoline quinone (PQQ) was an antioxid...

    journal_title：Biochemical and biophysical research communications

    pub_type： 杂志文章

    doi：10.1016/j.bbrc.2014.12.121

    authors： Luo L,Gan L,Liu Y,Tian W,Tong Z,Wang X,Huselstein C,Chen Y

    更新日期：2015-02-20 00:00:00