Leukocyte chemotaxis and pyoderma gangrenosum.

Abstract:

:Leukocyte chemotaxis (in five patients with pyoderma gangrenosum) was studied using a modification of the Boyden chamber method. In all patients the chemotactic response was significantly lower than in the controls. This abnormal chemotaxis was a result of an intrinsic neutrophil dysfunction. No significant difference was detected between the chemotactic response of leukocytes from patients with minimal or no skin involvement and those from patients with extensive lesions.

journal_name

Int J Dermatol

authors

Nerella P,Daniela A,Guido M,Fabbri P

doi

10.1111/j.1365-4362.1985.tb05359.x

subject

Has Abstract

pub_date

1985-01-01 00:00:00

pages

45-7

issue

1

eissn

0011-9059

issn

1365-4632

journal_volume

24

pub_type

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