Abstract:
PURPOSE:To retrospectively compare fusion fluorine 18 fluorodeoxyglucose (FDG) positron emission tomographic (PET)/computed tomographic (CT) imaging with CT imaging alone in the evaluation of yttrium 90 ((90)Y)-ibritumomab tiuxetan radioimmunotherapy treatment of B-cell non-Hodgkin lymphoma. MATERIALS AND METHODS:This HIPAA-compliant study was performed with approval from the University of Southern California Institutional Review Board and with informed consent. Five men and five women (mean age, 52 years; range, 38-70 years) with relapsed or refractory non-Hodgkin lymphoma underwent FDG PET/CT imaging both 14-27 days before treatment with (90)Y-ibritumomab tiuxetan and 4-6 months after treatment. Response after treatment was measured with CT imaging as complete response, partial response, or stable or progressive disease, as defined according to published criteria from a National Cancer Institute-sponsored international workshop. Response after treatment was measured with PET as complete response, partial response, or stable or progressive disease, as defined according to published criteria of the European Organization for Research and Treatment of Cancer. Responses were determined by three interpreters in consensus. RESULTS:Interpretation of CT images alone resulted in classification of eight (80%) of 10 patients as responders to treatment, with two patients (20%) classified as having complete response. At reevaluation with fused PET/CT images, two patients (20%) had residual lesions at CT that did not show evidence of FDG avidity. These two patients, classified as partial responders according to CT criteria alone, were classified as complete responders at PET/CT. Both of these patients were free of evident disease at 18 or more months of follow-up. CONCLUSION:The use of combined FDG PET/CT may enable superior assessment of response to (90)Y-ibritumomab tiuxetan treatment than the use of CT alone, at which one may underestimate (90)Y-ibritumomab tiuxetan response by considering inactive residual CT masses to be residual disease.
journal_name
Radiologyjournal_title
Radiologyauthors
Ulaner GA,Colletti PM,Conti PSdoi
10.1148/radiol.2463060588subject
Has Abstractpub_date
2008-03-01 00:00:00pages
895-902issue
3eissn
0033-8419issn
1527-1315pii
2463060588journal_volume
246pub_type
杂志文章相关文献
RADIOLOGY文献大全abstract:PURPOSE:To evaluate the ability to depict anatomy and complications of renal vascular transplant with unenhanced magnetic resonance (MR) angiography with spatial labeling with multiple inversion pulses (SLEEK) and to compare the results with color Doppler (CD) ultrasonography (US), digital subtraction angiography (DSA)...
journal_title:Radiology
pub_type: 杂志文章
doi:10.1148/radiol.14131800
更新日期:2014-06-01 00:00:00
abstract:PURPOSE:To evaluate the frequency of "missing" sternal ossification center (asynchronous non-ossification) in young children. MATERIALS AND METHODS:Lateral chest radiographs obtained in 229 children (mean age, 3.7 years) were retrospectively evaluated for sternal ossification. Four superior sternal segments were consi...
journal_title:Radiology
pub_type: 杂志文章
doi:10.1148/radiol.2241011202
更新日期:2002-07-01 00:00:00
abstract::Purpose To develop and validate a deep learning algorithm that predicts the final diagnosis of Alzheimer disease (AD), mild cognitive impairment, or neither at fluorine 18 (18F) fluorodeoxyglucose (FDG) PET of the brain and compare its performance to that of radiologic readers. Materials and Methods Prospective 18F-FD...
journal_title:Radiology
pub_type: 杂志文章
doi:10.1148/radiol.2018180958
更新日期:2019-02-01 00:00:00
abstract:PURPOSE:To evaluate the prognostic value of volumetric computed tomography (CT) for therapy control in patients treated with repeated transarterial chemoembolization (TACE) for hepatocellular carcinoma (HCC). MATERIALS AND METHODS:Eighty-five patients with histologically proved HCC underwent 182 TACE procedures with 5...
journal_title:Radiology
pub_type: 杂志文章
doi:10.1148/radiology.214.2.r00fe06349
更新日期:2000-02-01 00:00:00
abstract:PURPOSE:To estimate the fraction of moving blood in tissue with power Doppler ultrasound (US). MATERIALS AND METHODS:Power Doppler US measurements of moving scatterers in a flow tube were made as a function of successive dilutions of the perfusate. Measurements were normalized relative to the maximum Doppler power in ...
journal_title:Radiology
pub_type: 杂志文章
doi:10.1148/radiology.197.1.7568820
更新日期:1995-10-01 00:00:00
abstract::A basic understanding of shock wave generation is essential for the radiologist who performs gallstone lithotripsy. Shock waves differ from ordinary acoustic waves in that they have a rapid rise time, a positive pressure component that gives rise to compressive forces approaching 1,000 atm, and a low-amplitude sustain...
journal_title:Radiology
pub_type: 杂志文章
doi:10.1148/radiology.178.2.1987600
更新日期:1991-02-01 00:00:00
abstract::Purpose To perform an intra-animal comparison between (a) three-dimensional (3D) molecularly targeted ultrasonography (US) by using clinical-grade vascular endothelial growth factor receptor 2 (VEGFR2)-targeted microbubbles and (b) 3D dynamic contrast material-enhanced (DCE) US by using nontargeted microbubbles for as...
journal_title:Radiology
pub_type: 杂志文章
doi:10.1148/radiol.2016160032
更新日期:2017-02-01 00:00:00
abstract::Acute clinically significant hemobilia occurred after percutaneous transhepatic biliary drainage. Investigations revealed a fistula between a peripheral bile duct and a branch of the portal vein. Hemostasis was obtained by balloon tamponade at the site of the fistula. ...
journal_title:Radiology
pub_type: 杂志文章
doi:10.1148/radiology.154.3.3155870
更新日期:1985-03-01 00:00:00
abstract::Detection of specific tumor sites was studied with scintigraphy and radiolabeled human IgM monoclonal antibodies (MoAbs). Ten patients with metastatic breast cancer received an infusion of one of three indium-111-labeled anti-breast carcinoma MoAbs. The time of infusion ranged from 30 minutes to 2 hours. Three patient...
journal_title:Radiology
pub_type: 杂志文章
doi:10.1148/radiology.167.1.3347750
更新日期:1988-04-01 00:00:00
abstract:PURPOSE:To identify the complications and imaging findings related to lymphangioleiomyomatosis (LAM) after lung transplantation. MATERIALS AND METHODS:The authors retrospectively reviewed the clinical histories and imaging studies of 13 patients from five major medical centers who underwent unilateral (n = 8) or bilat...
journal_title:Radiology
pub_type: 杂志文章
doi:10.1148/radiology.210.2.r99fe11325
更新日期:1999-02-01 00:00:00
abstract:PURPOSE:To determine if three-dimensional (3D) ultrasonography (US) improves the ability to define the location and extent of facial clefting prenatally compared with two-dimensional (2D) US. MATERIALS AND METHODS:Thirty-one fetuses suspected of having a facial cleft were examined prospectively with 2D and 3D US. Foll...
journal_title:Radiology
pub_type: 杂志文章
doi:10.1148/radiology.217.1.r00oc18236
更新日期:2000-10-01 00:00:00
abstract::Background Mammography screening reduces breast cancer mortality, but a proportion of breast cancers are missed and are detected at later stages or develop during between-screening intervals. Purpose To develop a risk model based on negative mammograms that identifies women likely to be diagnosed with breast cancer be...
journal_title:Radiology
pub_type: 杂志文章
doi:10.1148/radiol.2020201620
更新日期:2020-11-01 00:00:00
abstract::Eight patients with aneurysms of the right ventricular outflow tract patch following tetralogy of Fallot repair were found to have residual distal obstructions. The site of such an obstruction must be carefully documented preoperatively because failure to relieve significant distal obstruction may result in recurrent ...
journal_title:Radiology
pub_type: 杂志文章
doi:10.1148/radiology.167.1.3347710
更新日期:1988-04-01 00:00:00
abstract:PURPOSE:To measure the proportion of high-cost imaging generated by a radiologist's recommendation and to identify the imaging findings resulting in follow-up. MATERIALS AND METHODS:This retrospective HIPAA-compliant study had institutional review board approval, with waiver of informed consent. A recommended examinat...
journal_title:Radiology
pub_type: 杂志文章
doi:10.1148/radiol.11111091
更新日期:2012-02-01 00:00:00
abstract:PURPOSE:To determine whether hemangiomas and malignant tumors can be better differentiated at 1.5-T magnetic resonance imaging with use of more heavily T2-weighted conventional spin-echo sequences. MATERIALS AND METHODS:Eighty-three patients with focal liver lesions (50 malignant tumors, 24 hemangiomas, nine cysts) la...
journal_title:Radiology
pub_type: 杂志文章
doi:10.1148/radiology.193.1.8090920
更新日期:1994-10-01 00:00:00
abstract::Pedal lymphography was performed without the use of vital dyes in 510 patients. Lymphatic vessels were still readily identifiable by this method, due to their transparency, clarity, elasticity, distensibility, and characteristic branching pattern. Procedure time was shortened by 10-15 minutes without compromising the ...
journal_title:Radiology
pub_type: 杂志文章
doi:10.1148/133.3.795
更新日期:1979-12-01 00:00:00
abstract::A case of actinomycosis involving the pelvic cavity is reported. The patient had a pelvic mass clinically and radiographically. Barium enema examination showed a mass with extrinsic compression and fixed narrowing of the rectum with mucosal irregularity. A computed tomographic scan showed a pelvic mass displacing the ...
journal_title:Radiology
pub_type: 杂志文章
doi:10.1148/radiology.148.2.6867330
更新日期:1983-08-01 00:00:00
abstract::Purpose To assess whether contrast material-enhanced ultrasonography (US) can be used to differentiate responders from nonresponders among patients with clinically active Crohn disease after 6 weeks of pharmacologic treatment. Materials and Methods This prospective study was approved by our ethics committee, and writt...
journal_title:Radiology
pub_type: 杂志文章
doi:10.1148/radiol.2016152461
更新日期:2016-11-01 00:00:00
abstract::The radiographic demonstration of lymph node involvement in amyloidosis is rare. Of 12 previously reported cases with lymph node enlargement, two also showed calcified nodes. This paper presents two new cases, one of which illustrates previously unreported findings. Recent advances that help to explain the pathogenesi...
journal_title:Radiology
pub_type: 杂志文章
doi:10.1148/radiology.138.1.7455070
更新日期:1981-01-01 00:00:00
abstract:PURPOSE:To determine if volumetric changes of diffusion-weighted and contrast material-enhanced magnetic resonance (MR) imaging can help assess early tumor response to intraarterial therapy (IAT) in neuroendocrine liver metastasis (NELM). MATERIALS AND METHODS:This retrospective single-center comprehensive imaging ana...
journal_title:Radiology
pub_type: 杂志文章
doi:10.1148/radiol.12120495
更新日期:2013-02-01 00:00:00
abstract:PURPOSE:To prospectively develop and evaluate the accuracy of a duplex Doppler ultrasonographic (US) index for predicting the presence or absence of esophageal varices in patients with compensated cirrhosis (Child-Pugh class A) by using endoscopy as the reference standard. MATERIALS AND METHODS:The study had instituti...
journal_title:Radiology
pub_type: 杂志文章
doi:10.1148/radiol.2481071257
更新日期:2008-07-01 00:00:00
abstract:PURPOSE:To assess the spectrum of complications after emergency tube thoracostomy (TT) and show the role of computed tomography (CT) in detection of these abnormalities. MATERIALS AND METHODS:CT scans, chest radiographs, and clinical data were reviewed in 51 patients (77 tubes) who underwent emergency TT after trauma....
journal_title:Radiology
pub_type: 杂志文章
doi:10.1148/radiology.195.2.7724780
更新日期:1995-05-01 00:00:00
abstract::This paper reviews some of the fundamental technical and diagnostic problems in clinical uroradiology, such as (a) the reason for the obstructive nephrogram; (b) why high-dose urography gives better studies than low-dose; (c) why the Trueta phenomenon has not been demonstrated in man; (d) the case for an intrarenal ar...
journal_title:Radiology
pub_type: 杂志文章,评审
doi:10.1148/116.2.259
更新日期:1975-08-01 00:00:00
abstract::Color Doppler imaging (CDI) can demonstrate the relative direction and velocity of blood flow in color, superimposed on a conventional gray-scale ultrasound image that depicts stationary tissue. Twenty-five infants were studied with portable CDI in the coronal, sagittal, and axial planes. Bilateral antegrade flow was ...
journal_title:Radiology
pub_type: 杂志文章
doi:10.1148/radiology.167.2.3282250
更新日期:1988-05-01 00:00:00
abstract::The rates of diabetes, obesity, and metabolic disease have reached epidemic proportions worldwide. In recent years there has been renewed interest in combating these diseases not only by modifying energy intake and lifestyle factors, but also by inducing endogenous energy expenditure. This approach has largely been st...
journal_title:Radiology
pub_type: 杂志文章,评审
doi:10.1148/radiol.2016150390
更新日期:2016-07-01 00:00:00
abstract::Background Among breast cancer survivors, detecting a breast cancer when it is asymptomatic (rather than symptomatic) improves survival; thus, imaging surveillance in these patients is warranted. Digital breast tomosynthesis (DBT) is used for screening, but data on DBT for surveillance in this high-risk population are...
journal_title:Radiology
pub_type: 杂志文章
doi:10.1148/radiol.2020201854
更新日期:2021-02-01 00:00:00
abstract::Multiple renal arteries originating from the aortoiliac vessels were identified angiographically in 44% of 444 prospective renal donors. Bilateral multiple renal arteries were identified in 12%. With good immunological donor-recipient matching, 17 kidneys with multiple renal arteries were transplanted with excellent r...
journal_title:Radiology
pub_type: 杂志文章
doi:10.1148/133.1.45
更新日期:1979-10-01 00:00:00
abstract::With the recent improvements in diagnosis and treatment of distal radius and carpal injuries, the hand surgeons' expectations of relevant radiologic interpretation of imaging studies are heightened. Conventional radiographic examinations, as well as more sophisticated and invasive studies, have important roles in the ...
journal_title:Radiology
pub_type: 杂志文章,评审
doi:10.1148/radiology.219.1.r01ap1311
更新日期:2001-04-01 00:00:00
abstract:PURPOSE:To determine technical success with percutaneous abscess drainage (PAD) in patients with Crohn disease during 14 years. MATERIALS AND METHODS:Medical records of 32 patients with Crohn disease who underwent PAD from 1985 to 1999 were reviewed. Results of abscess drainage and nature of subsequent surgical proced...
journal_title:Radiology
pub_type: 杂志文章
doi:10.1148/radiol.2223010554
更新日期:2002-03-01 00:00:00
abstract:PURPOSE:To determine the feasibility of mapping the spatial variation of cartilage T2 relaxation time in vivo in the pediatric knee with a 1.5-T clinical magnetic resonance (MR) imaging system and the manufacturer's body gradient coil. MATERIALS AND METHODS:Twenty-five children and adolescents (age range, 5-17 years; ...
journal_title:Radiology
pub_type: 杂志文章
doi:10.1148/radiol.2251011461
更新日期:2002-10-01 00:00:00