Application of an in vivo swine model for the determination of arsenic bioavailability in contaminated vegetables.

Abstract:

:Considerable information is available in the literature regarding the uptake of arsenic (As) from contaminated soil and irrigation water by vegetables. However, few studies have investigated As speciation in these crops while a dearth of information is available on As bioavailability following their consumption. In this study, the concentration and speciation of As in chard, radish, lettuce and mung beans was determined following hydroponic growth of the vegetables using As-contaminated water. In addition, As bioavailability was assessed using an in vivo swine feeding assay. While As concentrations ranged from 3.0 to 84.2mg As kg(-1) (dry weight), only inorganic As (arsenite and arsenate) was detected in the edible portions of the vegetables. When As bioavailability was assessed through monitoring blood plasma As concentrations following swine consumption of As-contaminated vegetables, between 50% and 100% of the administered As dose was absorbed and entered systemic circulation. Arsenic bioavailability decreased in the order mung beans>radish>lettuce=chard.

journal_name

Chemosphere

journal_title

Chemosphere

authors

Juhasz AL,Smith E,Weber J,Rees M,Rofe A,Kuchel T,Sansom L,Naidu R

doi

10.1016/j.chemosphere.2007.12.021

subject

Has Abstract

pub_date

2008-05-01 00:00:00

pages

1963-9

issue

10

eissn

0045-6535

issn

1879-1298

pii

S0045-6535(07)01547-0

journal_volume

71

pub_type

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