The value of incomplete mouse models of Alzheimer's disease.

abstract：PURPOSE:Postoperative infection still constitutes an important complication of spine surgery, and the optimal imaging modality for diagnosing postoperative spine infection has not yet been established. The aim of this prospective multicenter study was to assess the diagnostic performance of three imaging modalities in ...

journal_title：European journal of nuclear medicine and molecular imaging

authors： Paez D,Sathekge MM,Douis H,Giammarile F,Fatima S,Dhal A,Puri SK,Erba PA,Lazzeri E,Ferrando R,Filho PA,Magboo VP,Morozova O,Núñez R,Pellet O,Mariani G

更新日期：2020-11-18 00:00:00

abstract：PURPOSE:The purpose of this study was to map treatment-induced (99m)Tc-Hynic-rh-annexin V uptake in normal tissues using co-registration of SPECT and CT. METHODS:Nineteen patients (11 male, 8 female, mean age 57 years) with various malignant tumours (12 lymphomas, four non-small cell lung cancers and three head and ne...

journal_title：European journal of nuclear medicine and molecular imaging

authors： Kartachova MS,Valdés Olmos RA,Haas RL,Hoebers FJ,van den Brekel MW,van Zandwijk N,Herk Mv,Verheij M

更新日期：2006-08-01 00:00:00

abstract：:Multiple myeloma (MM) is characterized by a monoclonal plasma cell population in the bone marrow. Lytic lesions occur in up to 90 % of patients. For many years, whole-body X-ray (WBX) was the method of choice for detecting skeleton abnormalities. However, the value of WBX in relapsing disease is limited because lesion...

journal_title：European journal of nuclear medicine and molecular imaging

authors： de Waal EGM,Glaudemans AWJM,Schröder CP,Vellenga E,Slart RHJA

更新日期：2017-02-01 00:00:00

abstract：PURPOSE:To assess the value of SPECT/CT in patients with carpal boss (CB). METHODS:In 24 wrists with CB (18 right-sided, 6 left-sided) in 21 patients, planar images and SPECT/CT images were obtained. Three patients had bilateral CB. The grade of uptake (0 absent, 1 low, 2 moderate, 3 high) on planar imaging and SPECT/...

journal_title：European journal of nuclear medicine and molecular imaging

authors： Bhure U,Hug U,Huellner MW,Grünig H,Zander A,Del Sol Pérez Lago M,Strobel K

更新日期：2015-11-01 00:00:00

abstract：PURPOSE:PET has been proven to be helpful in the delineation of gross tumour volume (GTV) for external radiation therapy in several tumour entities. The aim of this study was to determine if [(11)C]choline PET could be used to localize the carcinomatous tissue within the prostate in order to specifically target this ar...

journal_title：European journal of nuclear medicine and molecular imaging

authors： Bundschuh RA,Wendl CM,Weirich G,Eiber M,Souvatzoglou M,Treiber U,Kübler H,Maurer T,Gschwend JE,Geinitz H,Grosu AL,Ziegler SI,Krause BJ

更新日期：2013-06-01 00:00:00

abstract：PURPOSE:This study was designed to determine safety, tolerability, and radiation burden of a [(68)Ga]NODAGA-RGD-PET for imaging integrin αvβ3 expression in patients with hepatocellular carcinoma (HCC) and liver cirrhosis. Moreover, metabolic stability and biokinetic data were compiled. METHODS:After injection of 154-1...

journal_title：European journal of nuclear medicine and molecular imaging

authors： Haubner R,Finkenstedt A,Stegmayr A,Rangger C,Decristoforo C,Zoller H,Virgolini IJ

更新日期：2016-10-01 00:00:00

abstract：PURPOSE:Brain imaging of FDG uptake and cerebrospinal fluid (CSF) concentration of amyloid-beta 1-42 (Abeta(1-42)) or tau proteins are promising biomarkers in the diagnosis of Alzheimer's disease (AD). There is still uncertainty regarding any association between decreased FDG uptake and alterations in CSF markers. MET...

journal_title：European journal of nuclear medicine and molecular imaging

authors： Arlt S,Brassen S,Jahn H,Wilke F,Eichenlaub M,Apostolova I,Wenzel F,Thiele F,Young S,Buchert R

更新日期：2009-07-01 00:00:00

abstract：PURPOSE:The aim of the study was to estimate normal ranges and test-retest measures for various parameters characterising dopamine metabolism from a prolonged (18)F-dopa positron emission tomography (PET) measurement using a reference tissue model and compare their value for the detection of early Parkinson's disease (...

journal_title：European journal of nuclear medicine and molecular imaging

authors： Oehme L,Perick M,Beuthien-Baumann B,Wolz M,Storch A,Löhle M,Herting B,Langner J,van den Hoff J,Reichmann H,Kotzerke J

更新日期：2011-08-01 00:00:00

abstract：PURPOSE:To elucidate the prognostic role of post-therapeutic (18)F-fluorodeoxyglucose ((18)F-FDG) positron emission tomography (PET), we conducted a retrospective cohort study analysing the clinical factors that affect overall survival after non-operative therapy for unresectable hepatocellular carcinoma (HCC). METHOD...

journal_title：European journal of nuclear medicine and molecular imaging

authors： Higashi T,Hatano E,Ikai I,Nishii R,Nakamoto Y,Ishizu K,Suga T,Kawashima H,Togashi K,Seo S,Kitamura K,Takada Y,Uemoto S

更新日期：2010-03-01 00:00:00

abstract：:Serotonin-1A (5-HT(1A)) receptors are implicated in neurochemical mechanisms underlying anxiety and depression and their treatment. Animal studies have suggested that 4-(2'-methoxyphenyl)-1-[2'-[ N-(2"-pyridinyl)- p-[(18)F]fluorobenzamido] ethyl] piperazine ( p-MPPF) may be a suitable positron emission tomography (PET...

journal_title：European journal of nuclear medicine and molecular imaging

authors： Sanabria-Bohórquez SM,Biver F,Damhaut P,Wikler D,Veraart C,Goldman S

更新日期：2002-01-01 00:00:00

abstract：PURPOSE:The objective of this study was to evaluate whether 68Ga-PSMA PET/CT whole-body tumor burden (PSMAwbtb) is associated with clinical parameters and laboratory parameters in prostate cancer patients. METHODS:We retrospectively evaluated prostate cancer patients submitted to PSMA PET/CT for primary staging purpos...

journal_title：European journal of nuclear medicine and molecular imaging

authors： Santos A,Mattiolli A,Carvalheira JB,Ferreira U,Camacho M,Silva C,Costa F,Matheus W,Lima M,Etchebehere E

更新日期：2021-02-01 00:00:00

abstract：PURPOSE:Focal congenital hyperinsulinism (CHI) is curable by surgery, which is why identification of the focal lesion is crucial. We aimed to determine the use of 18F-fluoro-dihydroxyphenylalanine (18F-DOPA) PET/CT vs. 68Ga-1,4,7,10-tetraazacyclododecane-1,4,7,10-tetraacetic-acid-1-Nal3-octreotide (68Ga-DOTANOC) PET/CT...

journal_title：European journal of nuclear medicine and molecular imaging

authors： Christiansen CD,Petersen H,Nielsen AL,Detlefsen S,Brusgaard K,Rasmussen L,Melikyan M,Ekström K,Globa E,Rasmussen AH,Hovendal C,Christesen HT

更新日期：2018-02-01 00:00:00

abstract：PURPOSE:Radioembolization (RE) is a promising treatment option for biliary tract cancers (BTC). We report here the largest series to date using this treatment modality. METHODS:We retrospectively studied data from 64 patients treated outside prospective clinical trial at our institution. We studied baseline characteri...

journal_title：European journal of nuclear medicine and molecular imaging

authors： Bourien H,Palard X,Rolland Y,Le Du F,Beuzit L,Uguen T,Le Sourd S,Pracht M,Manceau V,Lièvre A,Boudjema K,Garin E,Edeline J

更新日期：2019-03-01 00:00:00

abstract：PURPOSE:Penile cancer (PC) is a rare neoplasm with an aggressive behavior and variable prognosis. Lymph node (LN) involvement and pathological features of the primary lesion have been proven to be the most important survival factors. Positron emission tomography/computed tomography with fluorodeoxyglucose labelled with...

journal_title：European journal of nuclear medicine and molecular imaging

authors： Salazar A,Júnior EP,Salles PGO,Silva-Filho R,Reis EA,Mamede M

更新日期：2019-04-01 00:00:00

abstract：INTRODUCTION:Positron emission tomography (PET) is a fully quantitative technology for imaging metabolic pathways and dynamic processes in vivo. Attenuation correction of raw PET data is a prerequisite for quantification and is typically based on separate transmission measurements. In PET/CT attenuation correction, how...

journal_title：European journal of nuclear medicine and molecular imaging

authors： Hofmann M,Pichler B,Schölkopf B,Beyer T

更新日期：2009-03-01 00:00:00

abstract：:The development of monofunctional DTPA derivatives has been a major breakthrough in the labelling of proteins or peptides with a variety of radiometals. Although this methodology is simple and useful for indium-111 labelling, the stability of these conjugates is too low for most therapeutic nuclides. Cyclic chelators,...

journal_title：European journal of nuclear medicine and molecular imaging

authors： Béhé M,Becker W,Gotthardt M,Angerstein C,Behr TM

更新日期：2003-08-01 00:00:00

abstract：:The iodinated cocaine derivative [(123)I]PE2I is a new selective ligand for in vivo studies of the dopamine transporter (DAT) with single-photon emission tomography (SPET). The aim of the present study was to describe a method for accurate quantification of binding data following a bolus injection of [(123)I]PE2I. Six...

journal_title：European journal of nuclear medicine and molecular imaging

authors： Pinborg LH,Videbaek C,Svarer C,Yndgaard S,Paulson OB,Knudsen GM

更新日期：2002-05-01 00:00:00

abstract：PURPOSE:Familial adenomatous polyposis (FAP) is characterised by colonic and duodenal adenomatous polyps that carry a risk of malignant transformation. Malignant degeneration of duodenal adenomas is difficult to detect. We speculated that 2-((18)F)-fluoro-2-deoxy-D: -glucose positron emission tomography (FDG-PET) might...

journal_title：European journal of nuclear medicine and molecular imaging

authors： van Kouwen MC,Drenth JP,van Krieken JH,van Goor H,Friederich P,Oyen WJ,Nagengast FM

更新日期：2006-03-01 00:00:00

abstract：PURPOSE:Pathologic complete response (pCR) to neoadjuvant chemotherapy (NAC) is commonly accepted as the gold standard to assess outcome after NAC in breast cancer patients. 18F-Fluorodeoxyglucose positron emission tomography/computed tomography (PET/CT) has unique value in tumor staging, predicting prognosis, and eval...

journal_title：European journal of nuclear medicine and molecular imaging

authors： Li P,Wang X,Xu C,Liu C,Zheng C,Fulham MJ,Feng D,Wang L,Song S,Huang G

更新日期：2020-05-01 00:00:00

abstract：PURPOSE:Aortic metabolic activity is suggested to correlate with presence and progression of aneurysmal disease, but has been inadequately studied. This study investigates the 2-[(18)F] fluoro-2-deoxy-D-glucose ((18)F-FDG) uptake in a population of infra-renal abdominal aortic aneurysms (AAA), compared to a matched non...

journal_title：European journal of nuclear medicine and molecular imaging

authors： Barwick TD,Lyons OT,Mikhaeel NG,Waltham M,O'Doherty MJ

更新日期：2014-12-01 00:00:00

abstract：PURPOSE:To evaluate the diagnostic potential of PET/MRI with [(18)F]FDG in recurrent ovarian and cervical cancer in comparison to PET/CT. METHODS:A group of 19 patients with suspected recurrence of pelvic malignancies (ovarian cancer, 11 patients; cervical cancer, 8 patients) scheduled for an [(18)F]FDG PET/CT were su...

journal_title：European journal of nuclear medicine and molecular imaging

authors： Beiderwellen K,Grueneisen J,Ruhlmann V,Buderath P,Aktas B,Heusch P,Kraff O,Forsting M,Lauenstein TC,Umutlu L

更新日期：2015-01-01 00:00:00

abstract：:Organ residence times were calculated for diagnostic intakes of (99m)Tc pertechnetate, 2,3-dimercaptosuccinic acid (DMSA), diethylene triamine penta-acetic acid (DTPA), hydroxymethylene diphosphonate (HDP), macroaggregated albumin (MAA) and mercapto-acetyltriglycine (MAG(3)) during the 1st and 3rd stages of pregnancy ...

journal_title：European journal of nuclear medicine and molecular imaging

authors： Saunders M,Palmer M,Preece A,Millard R

更新日期：2002-10-01 00:00:00

abstract：PURPOSE:Prostate-specific membrane antigen (PSMA) positron emission tomography (PET)/computed tomography (CT) is used for (re)staging prostate cancer (PCa) and as a biomarker for evaluating response to therapy, but lacks established response criteria. A panel of PCa experts in nuclear medicine, radiology, and/or urolog...

journal_title：European journal of nuclear medicine and molecular imaging

authors： Fanti S,Goffin K,Hadaschik BA,Herrmann K,Maurer T,MacLennan S,Oprea-Lager DE,Oyen WJ,Rouvière O,Mottet N,Bjartell A

更新日期：2021-02-01 00:00:00

abstract：PURPOSE:To determine the impact on clinical management of patients with high-risk (HR) prostate cancer at diagnosis and patients with biochemical recurrence (BCR) using a new kit form of 68Ga-prostate-specific membrane antigen (PSMA), namely tris(hydroxypyridinone) (THP)-PSMA, with positron emission tomography-computed...

journal_title：European journal of nuclear medicine and molecular imaging

authors： Kulkarni M,Hughes S,Mallia A,Gibson V,Young J,Aggarwal A,Morris S,Challacombe B,Popert R,Brown C,Cathcart P,Dasgupta P,Warbey VS,Cook GJR

更新日期：2020-03-01 00:00:00

abstract：PURPOSE:To evaluate the predictive value of early and late residual (18)F-fluorodeoxyglucose (FDG) and (18)F-fluorothymidine (FLT) uptake using different SUV measurements in PET in patients with advanced non-small-cell lung cancer (NSCLC) treated with erlotinib. METHODS:We retrospectively reviewed data from 30 patient...

journal_title：European journal of nuclear medicine and molecular imaging

authors： Kobe C,Scheffler M,Holstein A,Zander T,Nogova L,Lammertsma AA,Boellaard R,Neumaier B,Ullrich RT,Dietlein M,Wolf J,Kahraman D

更新日期：2012-07-01 00:00:00

abstract：PURPOSE:Patients with high-risk neuroblastoma have an increased risk of recurrence and relapse of disease and a very poor prognosis. 131I-metaiodobenzylguanidine (131I-mIBG) in combination with topotecan as a radiosensitizer can be an effective and relatively well-tolerated agent for the treatment of refractory neurobl...

journal_title：European journal of nuclear medicine and molecular imaging

authors： Genolla J,Rodriguez T,Minguez P,Lopez-Almaraz R,Llorens V,Echebarria A

更新日期：2019-07-01 00:00:00

abstract：PURPOSE:We previously reported in a small series of patients that (99m)Tc-3,3-diphosphono-1,2-propanodicarboxylic acid ((99m)Tc-DPD) scintigraphy tested positive in transthyretin-related (TTR) (both mutant and wild-type) but not in primary (AL) amyloidotic cardiomyopathy (AC). We extended our study to a larger cohort o...

journal_title：European journal of nuclear medicine and molecular imaging

authors： Rapezzi C,Quarta CC,Guidalotti PL,Longhi S,Pettinato C,Leone O,Ferlini A,Salvi F,Gallo P,Gagliardi C,Branzi A

更新日期：2011-03-01 00:00:00

abstract：INTRODUCTION:This study aims to reveal the feasibility and potential of molecular connectivity based on neurotransmission in comparison with the metabolic connectivity with an application to dopaminergic pathways. For this purpose, we propose to compare the neurotransmission connectivity findings using 123I-FP-CIT SPEC...

journal_title：European journal of nuclear medicine and molecular imaging

authors： Verger A,Horowitz T,Chawki MB,Eusebio A,Bordonne M,Azulay JP,Girard N,Guedj E

更新日期：2020-02-01 00:00:00

abstract：INTRODUCTION:Ischemia in hypertrophic cardiomyopathy (HCM) is caused by coronary microvascular dysfunction (CMD), which is detected by measuring myocardial blood flow (MBF) with PET. Whether CMD may be associated with ischemic left ventricular (LV) dysfunction is unclear. We therefore assessed LV ejection fraction (EF)...

journal_title：European journal of nuclear medicine and molecular imaging

authors： Sciagrà R,Calabretta R,Cipollini F,Passeri A,Castello A,Cecchi F,Olivotto I,Pupi A

更新日期：2017-05-01 00:00:00

abstract：:As measurement of glomerular filtration rate (GFR) is now generally the responsibility of departments of nuclear medicine, it is important for nuclear medicine physicians and scientists to understand the pharmacokinetics of the indicators and radiotracers that are used, generally known as filtration markers. The singl...

journal_title：European journal of nuclear medicine and molecular imaging

authors： Peters AM

更新日期：2004-01-01 00:00:00