Abstract:
:The feeding activity of domesticated and wild rats was studied. The rats obtained all their food by lever pressing in two-lever operant chambers. Concurrent variable interval (VI) and concurrent variable ratio (VR) schedules operated continuously for successive 4-day periods. Feeding occurred as regular, discrete meals, mostly during the night. The schedules did not affect the number or size of meals or the total amount eaten. The interval schedules significantly extended the duration of meals and reduced intermeal intervals. Lever pressing was characterised on concurrent VI schedules by low response rates and frequent alternation and that on concurrent VR schedules by higher response rates confined to one lever. The wild rats ate significantly more than the domesticated rats by increasing the number but not the size of meals, primarily during the night. Feeding behaviour and operant responding are discussed in relation to the effects of domestication and economy of effort in food-seeking. The inhibition caused by handling and food deprivation, which impairs the performance of wild rodents in short sessions is avoided by providing self-maintenance conditions.
journal_name
Behav Brain Resjournal_title
Behavioural brain researchauthors
Shepherd DSdoi
10.1016/0166-4328(86)90050-1subject
Has Abstractpub_date
1986-01-01 00:00:00pages
83-7issue
1eissn
0166-4328issn
1872-7549pii
0166-4328(86)90050-1journal_volume
19pub_type
杂志文章abstract::Methylphenidate (MPH) is widely used as a "nootropic" agent and in the treatment of disorders of attention, and has been shown to modulate synaptic plasticity in vitro. Here we present in vivo evidence that this MPH-induced metaplasticity can last long after the end of treatment. MPH (0, 0.2, 1 and 5mg/kg) was adminis...
journal_title:Behavioural brain research
pub_type: 杂志文章
doi:10.1016/j.bbr.2015.05.009
更新日期:2015-09-15 00:00:00
abstract::Mild traumatic brain injury is a common outcome of blast exposure, and current literature indicates high rates of comorbid posttraumatic stress disorder (PTSD) in military personnel. Blast-exposed rats display PTSD-like behavior, suggesting relationships may exist between PTSD and blast exposure. Other studies demonst...
journal_title:Behavioural brain research
pub_type: 杂志文章
doi:10.1016/j.bbr.2019.04.009
更新日期:2019-08-05 00:00:00
abstract::Bilateral intranigral infusions of three different peptide agonists were made in rats exposed to fluphenazine decanoate, 30 mg/kg/month (FLU) or vehicle (CON) for seven months. Oral movements were monitored repeatedly during the neuroleptic pretreatment period, as well as before the intranigral infusion and during a 9...
journal_title:Behavioural brain research
pub_type: 杂志文章
doi:10.1016/0166-4328(93)90064-w
更新日期:1993-10-21 00:00:00
abstract::We examined the long-term effects of administration of (S)-alpha-fluoromethylhistidine (FMH), a specific inhibitor of histidine decarboxylase, on the spontaneous locomotor activity, food intake and brain contents of histamine, catecholamines, serotonin and amino acids of ICR mice. The distance of ambulation and number...
journal_title:Behavioural brain research
pub_type: 杂志文章
doi:10.1016/0166-4328(96)00059-9
更新日期:1995-12-14 00:00:00
abstract::In the hippocampus of freely moving rats, neurons have been recorded that fire predominantly when the animal travels through a particular area while exploring the environment (so-called 'place cells'). This study investigates if the neuronal firing characteristics of such cells are modulated by attention, expectation ...
journal_title:Behavioural brain research
pub_type: 杂志文章
doi:10.1016/s0166-4328(02)00422-9
更新日期:2003-06-16 00:00:00
abstract::Recent evidence indicates that the hippocampus contributes to the control of defensive behaviors in rodents. Here, electrical stimulation (1s, 60 Hz) of the rat dorsal hippocampus inhibited defense in the elevated plus maze (increased open arm exploration) and shock-probe burying test (reduced burying duration), while...
journal_title:Behavioural brain research
pub_type: 杂志文章
doi:10.1016/j.bbr.2007.07.030
更新日期:2008-01-10 00:00:00
abstract::In recent years, considerable emphasis has been placed upon the putative role of nucleus accumbens dopamine systems in appetitive motivation and positive reinforcement. However, considerable evidence indicates that brain dopamine in general, and nucleus accumbens dopamine in particular, is involved in aspects of avers...
journal_title:Behavioural brain research
pub_type: 杂志文章,评审
doi:10.1016/0166-4328(94)90153-8
更新日期:1994-04-18 00:00:00
abstract::Nicotine has a broad spectrum of behavioural effects. A considerable body of data has emerged indicating genetic factors regulate the behavioural effects of nicotine. Experimental genetic techniques have been invaluable in generating knowledge on the interrelationship of genetic factors and behavioural responsiveness ...
journal_title:Behavioural brain research
pub_type: 杂志文章,评审
doi:10.1016/s0166-4328(00)00198-4
更新日期:2000-08-01 00:00:00
abstract::Data are reviewed that suggest a common neural system may be involved in the rewarding properties of psychomotor stimulant and opiate drugs. This neural system corresponds to elements in the ventral tegmental dopamine system with cell bodies in the ventral tegmentum and axon terminals in the nucleus accumbens. Several...
journal_title:Behavioural brain research
pub_type: 杂志文章
doi:10.1016/0166-4328(86)90032-x
更新日期:1986-11-01 00:00:00
abstract::This study examined the learning abilities of mature rhesus monkeys that had been subjected to bilateral amygdalectomy either during infancy or adulthood. At 4 1/2 years of age, 6 female monkeys that had been amygdalectomized in infancy and 12 neurologically intact controls were trained on a barpress avoidance problem...
journal_title:Behavioural brain research
pub_type: 杂志文章
doi:10.1016/0166-4328(81)90039-5
更新日期:1981-01-01 00:00:00
abstract::Chemotherapy related cognitive impairment (CTRC; "chemobrain") is a syndrome that is associated with the impairment of various aspects of cognition, including executive function, processing speed, and multitasking. The role of neurotransmitter release in the expression of cognitive impairments is not well known. In th...
journal_title:Behavioural brain research
pub_type: 杂志文章
doi:10.1016/j.bbr.2019.01.007
更新日期:2019-04-19 00:00:00
abstract::These experiments examined the mnemonic functions of hippocampus and dorsal striatum in Pavlovian aversive conditioning. Rats were trained in a single session by presenting three paired tones and footshocks. Immediately after training, they were given microinjections of D-amphetamine or vehicle into either dorsal hipp...
journal_title:Behavioural brain research
pub_type: 杂志文章
doi:10.1016/s0166-4328(02)00402-3
更新日期:2003-06-16 00:00:00
abstract::The possible effect of different cholecystokinin (CCK) receptor antagonists (MK-329 and L-365260) on the maintenance and reactivation of morphine conditioned place preference (CPP) were investigated in rats, respectively. The results show that the maintenance of morphine CPP could be induced by injection of morphine (...
journal_title:Behavioural brain research
pub_type: 杂志文章
doi:10.1016/s0166-4328(00)00361-2
更新日期:2001-04-08 00:00:00
abstract::Social norms are a common motivator or de-motivator of behavior through the need of humans to comply with acceptable behaviors of their social groups. Converging evidence from functional neuroimaging and noninvasive brain stimulation studies suggest that the right dorsolateral prefrontal cortex (rDLPFC) is involved in...
journal_title:Behavioural brain research
pub_type: 杂志文章
doi:10.1016/j.bbr.2018.12.040
更新日期:2019-04-01 00:00:00
abstract::The influence of early experience and strain differences on auditory discrimination learning, open field behaviour and brain size was investigated in wild-type Mongolian gerbils (strain Ugoe:MU95) raised in the wild (wild F-0) or in the laboratory (wild F-1) and in domesticated Laboratory Gerbils (LAB). Adult males we...
journal_title:Behavioural brain research
pub_type: 杂志文章
doi:10.1016/j.bbr.2006.05.025
更新日期:2006-10-02 00:00:00
abstract::The context preexposure facilitation effect (CPFE) is a variant of context fear conditioning in which context preexposure facilitates conditioning to immediate foot shock. Learning about context (preexposure), associating the context with shock (training), and expression of context fear (testing) occur in successive p...
journal_title:Behavioural brain research
pub_type: 杂志文章
doi:10.1016/j.bbr.2013.03.043
更新日期:2013-07-01 00:00:00
abstract::Alcohol abuse is a major medical problem. Zebrafish have been proposed to model alcohol related human disorders. Alcohol impairs learning and memory. Here, we analyze the effects of alcohol on performance of zebrafish in a recently developed latent learning paradigm. We employ a 2×3×2 experimental design (chronic×acut...
journal_title:Behavioural brain research
pub_type: 杂志文章
doi:10.1016/j.bbr.2014.12.013
更新日期:2015-04-01 00:00:00
abstract::Structural and functional brain reorganisation can occur beyond the developmental maturation period and this was recently recognised as an intrinsic property of the human central nervous system. Brain injury or altered afferent input due to environmental changes, novel experience and learning new skills are known as m...
journal_title:Behavioural brain research
pub_type: 杂志文章,评审
doi:10.1016/j.bbr.2008.02.015
更新日期:2008-09-01 00:00:00
abstract::Our daily activities are comprised of motor routines, which are behavioral templates with specific goals, typically performed in an automatic fixed manner and without much conscious attention. Such routines can seem to resemble pathologic rituals that dominate the motor behavior of obsessive-compulsive disorder (OCD) ...
journal_title:Behavioural brain research
pub_type: 杂志文章
doi:10.1016/j.bbr.2010.03.051
更新日期:2010-09-01 00:00:00
abstract::S-100 beta, a gene triplicated in Down Syndrome (DS), is thought to play a role in development of the brain in general, and in the serotonergic neuronal system in particular. We have been studying an animal model of DS, based on overexpression of this gene. In the current study, we report on the social behaviors of th...
journal_title:Behavioural brain research
pub_type: 杂志文章
doi:10.1016/s0166-4328(02)00373-x
更新日期:2003-05-15 00:00:00
abstract::Memory processes may be independent, compete, operate in parallel, or interact. In accordance with this view, behavioral studies suggest that the hippocampus (HPC) and prefrontal cortex (PFC) may act as an integrated circuit during performance of tasks that require working memory over longer delays, whereas during sho...
journal_title:Behavioural brain research
pub_type: 杂志文章
doi:10.1016/j.bbr.2011.07.045
更新日期:2011-12-01 00:00:00
abstract::An enriched environment has been shown to influence brain plasticity and function by involving the action of brain-derived neurotrophic factor (BDNF). BDNF, which is synthesized as a precursor molecule (proBDNF) that undergoes proteolytic cleavage, plays an important role in synaptic plasticity and contributes to seve...
journal_title:Behavioural brain research
pub_type: 杂志文章
doi:10.1016/j.bbr.2014.02.022
更新日期:2014-05-15 00:00:00
abstract::The association between morphine withdrawal and depressive-like symptoms is well documented, however, the role of dynorphin/κ opioid receptor system and the underlying neural substrates have not been fully understood. In the present study, we found that four weeks morphine abstinence after a chronic escalating morphin...
journal_title:Behavioural brain research
pub_type: 杂志文章
doi:10.1016/j.bbr.2015.05.053
更新日期:2015-09-15 00:00:00
abstract::Increasing evidence suggests that a brain-gut-microbiome axis exists, which has the potential to play a major role in modulating behaviour. However, the role of this axis in cognition remains relatively unexplored. Probiotics, which are commensal bacteria offering potential health benefit, have been shown to decrease ...
journal_title:Behavioural brain research
pub_type: 杂志文章
doi:10.1016/j.bbr.2015.02.044
更新日期:2015-01-01 00:00:00
abstract::We analysed spatial and temporal characteristics of mouse locomotion and investigated whether mouse gait differed between strains and environments. To this end, we used two inbred strains of mice (BALB/cByJ and C57BL/6J) known for their contrasting inherent level of anxiety, in three different visual surroundings. The...
journal_title:Behavioural brain research
pub_type: 杂志文章
doi:10.1016/j.bbr.2005.10.001
更新日期:2006-02-28 00:00:00
abstract::Disruption of conditioned taste aversion (CTA) by tetrodotoxin (TTX) blockade of parabrachial nuclei elicited after ingestion of the gustatory CS and before administration of the visceral US is revealed by unchanged CS preference in retrieval test performed two days after acquisition. The universality of the above amn...
journal_title:Behavioural brain research
pub_type: 杂志文章
doi:10.1016/0166-4328(94)90060-4
更新日期:1994-01-31 00:00:00
abstract::Continuing previous efforts to develop the 4-vessel occlusion (4-VO) model of chronic cerebral hypoperfusion (CCH), here we evaluated whether permanent, stepwise 4-VO causes both learning deficits, hippocampal neurodegeneration and retinal lesion in young, middle-aged or aged rats. Chronic 4-VO was induced by ligation...
journal_title:Behavioural brain research
pub_type: 杂志文章
doi:10.1016/j.bbr.2008.10.023
更新日期:2009-02-11 00:00:00
abstract::In this study, tetrodotoxin (TTX) inactivation was employed to evaluate the involvement of the rat's orbitofrontal cortex (OFC) in hippocampus-dependent spatial memory using Morris water maze (MWM) and place avoidance learning (PAL) tasks. In Experiment 1, rats trained in MWM task with two blocks of four trials per da...
journal_title:Behavioural brain research
pub_type: 杂志文章
doi:10.1016/s0166-4328(03)00209-2
更新日期:2004-02-04 00:00:00
abstract::Previous studies with mice lacking 5-HT(1A) (1AKO) and 5-HT(1B) (1BKO) receptors in hippocampus-dependent learning and memory paradigms, suggest that these receptors play an important role in learning and memory, although their precise role is unclear. In the present study, 1AKO and 1BKO mice were studied in operant b...
journal_title:Behavioural brain research
pub_type: 杂志文章
doi:10.1016/s0166-4328(02)00345-5
更新日期:2003-05-15 00:00:00
abstract::Growing evidence suggests that testosterone may play a role in the pathophysiology of schizophrenia given that testosterone has been linked to cognition and negative symptoms in schizophrenia. Here, we determine the extent to which serum testosterone levels are related to neural activity in affective processing circui...
journal_title:Behavioural brain research
pub_type: 杂志文章
doi:10.1016/j.bbr.2015.03.020
更新日期:2015-06-01 00:00:00