Abstract:
:Haplotypes are useful in population genetics and medicine. Determining haplotypes in the absence of DNA samples from appropriate family members can be difficult and laborious. We have developed a rapid and reproducible method for haplotyping an individual in the absence of relatives. The method utilizes pairs of allele-specific PCR primers to differentially amplify each haplotype. Four amplifications can distinguish the haplotypes produced by two biallelic polymorphisms.
journal_name
Biotechniquesjournal_title
BioTechniquesauthors
Sarkar G,Sommer SSsubject
Has Abstractpub_date
1991-04-01 00:00:00pages
436, 438, 440issue
4eissn
0736-6205issn
1940-9818journal_volume
10pub_type
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