Pharmacokinetics of fentanyl in neonates.

abstract：BACKGROUND:In this prospective study, we compared the relationship between propofol concentrations and bispectral index (BIS) in children versus young adults anesthetized with target-controlled infusion (TCI) of propofol. METHODS:Forty-five prepubertal subjects (children) and 45 postpubertal subjects (adults) were stu...

journal_title：Anesthesia and analgesia

authors： Rigouzzo A,Girault L,Louvet N,Servin F,De-Smet T,Piat V,Seeman R,Murat I,Constant I

更新日期：2008-04-01 00:00:00

abstract：UNLABELLED:Although acute tolerance to analgesia develops rapidly with remifentanil, it is unknown whether acute tolerance also develops to its nonanalgesic effects. We investigated the analgesic and cardiorespiratory effects of remifentanil during a continuous infusion in a rabbit model. Ten tracheotomized New Zealand...

journal_title：Anesthesia and analgesia

authors： Hayashida M,Fukunaga A,Hanaoka K

更新日期：2003-11-01 00:00:00

abstract：:Spontaneous or evoked electrical brain activity is increasingly used to monitor general anesthesia. Previous studies investigated the variables from spontaneous electroencephalogram (EEG), acoustic (AEP), or somatosensory evoked potentials (SSEP). But, by monitoring them separately, the available information from simu...

journal_title：Anesthesia and analgesia

authors： Jeleazcov C,Schneider G,Daunderer M,Scheller B,Schüttler J,Schwilden H

更新日期：2006-10-01 00:00:00

abstract：UNLABELLED:Percutaneous needle liver biopsy is an important procedure for the diagnosis and evaluation of liver disease and is frequently associated with pain. In this prospective study, we investigated the prevalence and characteristics of this pain syndrome. Fifty-four subjects, who underwent liver biopsy under ultra...

journal_title：Anesthesia and analgesia

authors： Eisenberg E,Konopniki M,Veitsman E,Kramskay R,Gaitini D,Baruch Y

更新日期：2003-05-01 00:00:00

abstract：:Previous perfluorocarbon (PFC) emulsions have been associated with transient adverse events (i.e., platelet activation, decreased platelet count, febrile responses, changes in hemodynamic function). The Phase I studies described in this report were parallel, randomized, double-blinded, placebo-controlled studies condu...

journal_title：Anesthesia and analgesia

authors： Leese PT,Noveck RJ,Shorr JS,Woods CM,Flaim KE,Keipert PE

更新日期：2000-10-01 00:00:00

abstract：:Intraocular pressure (IOP) measurements in children are usually performed under nitrous oxide and halothane anesthesia. We studied the effects of both time and end-tidal halothane concentration on IOP in 80 children (mean age +/- SD = 4.5 +/- 2.9 yr), to determine the most optimal time to make such measurements in ane...

journal_title：Anesthesia and analgesia

authors： Watcha MF,Chu FC,Stevens JL,Forestner JE

更新日期：1990-08-01 00:00:00

abstract：:To evaluate the effects of high-frequency jet ventilation (HFJV) (f = 60, 120 breaths/min) and conventional mechanical ventilation (CMV) (f = 10, 20) during equivalent conditions of cardiac tamponade, stroke index (SI), intrapericardial pressure (IPP), airway pressure (P(aw)), and cardiac pressures were measured in an...

journal_title：Anesthesia and analgesia

authors： Goto K,Goto H,Benson KT,Unruh GK,Arakawa K

更新日期：1990-04-01 00:00:00

abstract：BACKGROUND:Severe exacerbation of chronic neuropathic pain often requires morphine in patients already treated with drugs such as tricyclic antidepressants, carbamazepine and gabapentin. However, it is unclear if a combination of these drugs intensifies the effects of morphine on the respiratory system and, if so, whet...

journal_title：Anesthesia and analgesia

authors： Kozer E,Levichek Z,Hoshino N,Kapur B,Leombruno J,Taguchi N,Garcia-Bournissen F,Koren G,Ito S

更新日期：2008-10-01 00:00:00

abstract：BACKGROUND:To prevent reflex-induced bronchoconstriction in patients with asthma, local anesthetics are commonly administered by aerosol or IV as adjunct medication. Lidocaine attenuates responsiveness to a neurally active stimulus that increases tone, but there is scant information about the effect of lidocaine on bas...

journal_title：Anesthesia and analgesia

authors： Chang HY,Togias A,Brown RH

更新日期：2007-05-01 00:00:00

abstract：UNLABELLED:We conducted a double-blinded study in 90 patients undergoing elective arthroscopic knee surgery to determine whether there is a role of inflammation in the analgesic efficacy of intraarticular piroxicam. Standardized general anesthetic techniques were used for all patients. At the end of the operation, afte...

journal_title：Anesthesia and analgesia

authors： Izdes S,Orhun S,Turanli S,Erkilic E,Kanbak O

更新日期：2003-10-01 00:00:00

abstract：BACKGROUND:We previously reported that the duration of hospitalization was not different between isoflurane and sevoflurane. But more plausible consequences of using soluble volatile anesthetics are delayed emergence from anesthesia and prolonged stays in the postanesthesia care unit (PACU). We therefore compared isofl...

journal_title：Anesthesia and analgesia

authors： Maheshwari K,Ahuja S,Mascha EJ,Cummings KC 3rd,Chahar P,Elsharkawy H,Kurz A,Turan A,Sessler DI

更新日期：2020-02-01 00:00:00

abstract：UNLABELLED:We examined the effects of two perioperative pain management techniques on recovery after laparotomy, as assessed by body weight (BW) and food consumption (FC). All rats received a preoperative intrathecal mixture of morphine plus bupivacaine combined with one of two treatments: (a) injection of slow-release...

journal_title：Anesthesia and analgesia

authors： Shavit Y,Fish G,Wolf G,Mayburd E,Meerson Y,Yirmiya R,Beilin B

更新日期：2005-10-01 00:00:00

abstract：:We studied 49 patients of ASA physical status I to determine cerebral anesthetic concentration on awakening calculated with end-tidal anesthetic concentration, when the end-tidal concentration decreased spontaneously. We also attempted to explain the difference in the average of the bracketing alveolar anesthetic conc...

journal_title：Anesthesia and analgesia

authors： Katoh T,Suguro Y,Kimura T,Ikeda K

更新日期：1993-11-01 00:00:00

abstract：BACKGROUND:I.v. injection of propofol during anesthetic induction induces pain. Ketamine has been shown to reduce injection pain. In this study, we established the optimal dose of ketamine to prevent the pain of injection with propofol. METHODS:Two hundred forty patients presenting for elective surgery were randomly a...

journal_title：Anesthesia and analgesia

authors： Koo SW,Cho SJ,Kim YK,Ham KD,Hwang JH

更新日期：2006-12-01 00:00:00

abstract：BACKGROUND:The rate of neuraxial analgesia during labor in France is one of the highest among high-income countries: 77% of vaginal deliveries in 2010. In this context, the question of how women's preferences for delivering without neuraxial analgesia relate to actual use is of interest. Our objective was to study the ...

journal_title：Anesthesia and analgesia

authors： Kpéa L,Bonnet MP,Le Ray C,Prunet C,Ducloy-Bouthors AS,Blondel B

更新日期：2015-09-01 00:00:00

abstract：BACKGROUND:Near-infrared spectroscopy is used during cardiac surgery to monitor the adequacy of cerebral perfusion. In this systematic review, we evaluated available data for adult patients to determine (1) whether decrements in cerebral oximetry during cardiac surgery are associated with stroke, postoperative cognitiv...

journal_title：Anesthesia and analgesia

authors： Zheng F,Sheinberg R,Yee MS,Ono M,Zheng Y,Hogue CW

更新日期：2013-03-01 00:00:00

abstract：BACKGROUND:For emergent procedures, in-house teams are required for immediate patient care. However, for many procedures, there is time to bring in a call team from home without increasing patient morbidity. Anesthesia providers taking subspecialty or backup call from home are required to return to the hospital within ...

journal_title：Anesthesia and analgesia

authors： Epstein RH,Dexter F,Diez C,Potnuru P

更新日期：2019-11-01 00:00:00

abstract：:The pharmacokinetics of sufentanil were studied in 28 pediatric patients undergoing cardiovascular procedures. Patients were divided into four groups on the basis of age: neonates (0-1 month, n = 9), infants (1-24 months, n = 7), children (2-12 yr, n = 7), and adolescents (12-18 yr, n = 5). Sufentanil 10-15 micrograms...

journal_title：Anesthesia and analgesia

authors： Greeley WJ,de Bruijn NP,Davis DP

更新日期：1987-11-01 00:00:00

abstract：BACKGROUND:Bilateral breast augmentation is an increasingly popular day-case procedure. Local infiltration with sedation is routinely used for its ease of application compared with the more complex and potentially riskier paravertebral blockade (PVB). We hypothesized that ropivacaine injected by experienced anesthesia ...

journal_title：Anesthesia and analgesia

authors： Gardiner S,Rudkin G,Cooter R,Field J,Bond M

更新日期：2012-11-01 00:00:00

abstract：BACKGROUND:In clinical anesthesia, robust surgical stress occasionally causes unintended light anesthesia during operation. To test the hypothesis that neural input condition could modify actions of general anesthetics as a result of presynaptic alteration in the central nervous system, we investigated the mechanisms b...

journal_title：Anesthesia and analgesia

authors： Hirota K,Sasaki R,Roth SH,Yamazaki M

更新日期：2010-06-01 00:00:00

abstract：BACKGROUND:Transporting patients under anesthesia care incurs numerous potential risks, especially for those with critical illness. The purpose of this study is to identify and report all pediatric anesthesia transport-associated adverse events from a preexisting database of perioperative adverse events. METHODS:An ex...

journal_title：Anesthesia and analgesia

authors： Haydar B,Baetzel A,Stewart M,Voepel-Lewis T,Malviya S,Christensen R

更新日期：2020-07-01 00:00:00

abstract：:We investigated the usefulness of peripheral flow index (PFI) measurement using a standard pulse oximetry digit probe for early prediction of successful regional blocks. Sixty-six patients scheduled for limb surgery underwent either axillary or sciatic block using a nerve stimulator technique with mepivacaine 1.5%. PF...

journal_title：Anesthesia and analgesia

authors： Galvin EM,Niehof S,Verbrugge SJ,Maissan I,Jahn A,Klein J,van Bommel J

更新日期：2006-07-01 00:00:00

abstract：:Median convulsant (CD50) and median lethal (LD50) doses of intraperitoneal lidocaine, bupivacaine, and etidocaine were determined in 149 mice. Another 496 mice were pretreated with intramuscular diazepam, lorazepam, or midazolam, 1 mg/kg. Fifteen minutes later, lidocaine, bupivacaine, or etidocaine was given intraperi...

journal_title：Anesthesia and analgesia

authors： de Jong RH,Bonin JD

更新日期：1981-06-01 00:00:00

abstract：BACKGROUND:Erythropoiesis-stimulating agents, such as erythropoietin (EPO), can be used to treat preoperative anemia. Some studies suggest an increased risk of mortality and thrombotic events, and use in cardiovascular surgery remains off-label. This study compares outcomes in cardiac surgery patients declining blood t...

journal_title：Anesthesia and analgesia

authors： Duce L,Cooter ML,McCartney SL,Lombard FW,Guinn NR

更新日期：2018-08-01 00:00:00

abstract：:The effects of three anesthetic techniques on liver function were compared in patients with mild alcoholic hepatitis who required surgery, both peripheral and superficial. Thirty patients were randomly assigned to receive one of three anesthetics: thiopental, nitrous oxide and oxygen, enflurane, plus muscle relaxant; ...

journal_title：Anesthesia and analgesia

authors： Zinn SE,Fairley HB,Glenn JD

更新日期：1985-05-01 00:00:00

abstract：BACKGROUND:Detection of ongoing spontaneous pain behaviors in laboratory animals remains a research challenge. Most preclinical pain studies measure elicited behavioral responses to an external noxious stimulus; however, ongoing spontaneous pain in humans and animals may be unrelated to hypersensitivity, and likely dim...

journal_title：Anesthesia and analgesia

authors： Ewan EE,Martin TJ

更新日期：2014-04-01 00:00:00

abstract：UNLABELLED:Heart transplantation in patients with increased pulmonary vascular resistance is often associated with postbypass right heart failure. We therefore compared the abilities of prostaglandin E(1) (PGE(1)) and inhaled nitric oxide to reduce pulmonary vascular resistance during heart transplantation. Patients un...

journal_title：Anesthesia and analgesia

authors： Rajek A,Pernerstorfer T,Kastner J,Mares P,Grabenwöger M,Sessler DI,Grubhofer G,Hiesmayr M

更新日期：2000-03-01 00:00:00

abstract：:Bispectral Index Scale (BIS)-guided closed-loop delivery of anesthetics has been extensively studied. We performed a meta-analysis of all the randomized clinical trials comparing efficacy and performance between BIS-guided closed-loop delivery and manually controlled administration of total IV anesthesia. Scopus, PubM...

journal_title：Anesthesia and analgesia

authors： Pasin L,Nardelli P,Pintaudi M,Greco M,Zambon M,Cabrini L,Zangrillo A

更新日期：2017-02-01 00:00:00

abstract：UNLABELLED:In a randomized trial, we compared topical anesthesia by a lidocaine-prilocaine cream (EMLA; Laboratorie ASTRA, Manterre, France) with subcutaneous local lidocaine infiltration for radial artery cannulation. Patients included 538 adults scheduled for coronary angiography using a radial approach. EMLA was app...

journal_title：Anesthesia and analgesia

authors： Joly LM,Spaulding C,Monchi M,Ali OS,Weber S,Benhamou D

更新日期：1998-08-01 00:00:00

abstract：UNLABELLED:We tested baicalin for its antiinflammatory and analgesic effects (and the mechanisms) in a rat model of carrageenan-evoked thermal hyperalgesia. Pre- or posttreatment with baicalin (10, 30, or 100 mg/kg intraperitoneally) caused a significant analgesic effect with a similar effect of dose-matched ibuprofen....

journal_title：Anesthesia and analgesia

authors： Chou TC,Chang LP,Li CY,Wong CS,Yang SP

更新日期：2003-12-01 00:00:00