Predictive value of myeloperoxidase to identify high risk patients admitted to the hospital with acute chest pain.

Abstract:

BACKGROUND:Myeloperoxidase (MPO) is a highly expressed enzyme due to leukocyte activation, with multiple atherogenic actions, including LDL cholesterol oxidation, and is related to the instability of atherosclerotic plaque. It is a predictor of adverse events in healthy individuals, patients with heart disease or those undergoing chest pain investigations. OBJECTIVE:To analyze the contribution of MPO to identify patients with acute chest pain, non-ST elevation ECG and at high risk for in-hospital adverse events. METHODS:Patients presenting acute chest pain and a non-ST elevation ECG, were admitted to the hospital and submitted to serum MPO level measurements and a structured examination protocol. RESULTS:From a cohort of 140 patients, 49 (35%) were diagnosed with acute coronary syndrome, of which 13 patients (9.3%) were diagnosed with non-ST elevation acute myocardial infarction (AMI) (troponin I >1.0 ng/mL). The best MPO cut-off point for AMI was identified as >100 pM using the ROC curve (AUC=0.662; CI 95%=0.532-0.793) revealing elevated sensitivity (92.3%) and negative predictive value (98.1%), however with low specificity (40.2%). In the multivariate analysis, MPO proved to be the only independent variable to diagnose AMI in evolution, with an odds ratio of 8.04 (p=0.048). CONCLUSION:In patients with acute chest pain and no ST elevation, high MPO levels upon admission to the hospital are an important tool to predict in-hospital adverse events, with an odds ratio of eight for the diagnosis of AMI.

journal_name

Arq Bras Cardiol

authors

Esporcatte R,Rey HC,Rangel FO,Rocha RM,Mendonça Filho HT,Dohmann HF,Albanesi Filho FM

doi

10.1590/s0066-782x2007001800005

subject

Has Abstract

pub_date

2007-12-01 00:00:00

pages

377-84

issue

6

eissn

0066-782X

issn

1678-4170

pii

S0066-782X2007001800005

journal_volume

89

pub_type

杂志文章
  • [Technical aspects of coronary sinus catheterization based on the atrial component of the intracavitary electrogram and radiological anatomy during the implantation procedure of a biventricular pacemaker].

    abstract:OBJECTIVE:To present a technical proposal based on the experience of 130 implantations using a simplified technique for coronary sinus catheterization, based on the atrial component of the intracavitary electrogram and radiological anatomy. METHODS:From October, 2001 to October, 2004, 130 biventricular pacemaker impla...

    journal_title:Arquivos brasileiros de cardiologia

    pub_type: 杂志文章

    doi:10.1590/s0066-782x2006000400005

    authors: Souza FS,Mortati NL,Braile DM,Vieira RW,Rojas SO,Rabelo AC,Souza JM,Oliveira SA

    更新日期:2006-04-01 00:00:00

  • The influence of health insurance plans on the long term outcome of patients with acute myocardial infarction.

    abstract:BACKGROUND:Little is known, especially in our country, about the influence of health insurance plans on the long term outcome of patients after acute myocardial infarction (AMI). OBJECTIVE:To assess the outcome of patients with AMI who are covered by the National Health System (SUS) or other health insurance plans. M...

    journal_title:Arquivos brasileiros de cardiologia

    pub_type: 杂志文章

    doi:10.1590/s0066-782x2008001800004

    authors: Nicolau JC,Baracioli LM,Serrano CV Jr,Giraldez RR,Kalil Filho R,Lima FG,Franken M,Ganem F,Lage RL,Truffa R

    更新日期:2008-12-01 00:00:00

  • Cardiovascular risk in vegetarians and omnivores: a comparative study.

    abstract:BACKGROUND:Clinical and epidemiological studies have demonstrated a strong association between eating habits and chronic diseases, particularly cardiovascular events, although not all the mechanisms of action are understood. OBJECTIVE:To describe and analyze the cardiovascular risk (CVR) in vegetarians and omnivores r...

    journal_title:Arquivos brasileiros de cardiologia

    pub_type: 杂志文章

    doi:10.1590/s0066-782x2007001600005

    authors: Teixeira Rde C,Molina Mdel C,Zandonade E,Mill JG

    更新日期:2007-10-01 00:00:00

  • Effect of penicillin G every three weeks on oral microflora by penicillin resistant Viridans Streptococci.

    abstract:BACKGROUND:Benzathine penicillin G every 3 weeks is the standard protocol for secondary prophylaxis for recurrent rheumatic fever. OBJECTIVE:Assess the effect of Benzathine penicillin G on Streptococcus sanguinis and Streptococcus oralis in patients with cardiac valvular disease due to rheumatic fever receiving second...

    journal_title:Arquivos brasileiros de cardiologia

    pub_type: 杂志文章

    doi:10.1590/s0066-782x2012005000038

    authors: Aguiar AA,Sampaio RO,Sampaio JL,Spina GS,Neves RS,Moreira LF,Grinberg M

    更新日期:2012-05-01 00:00:00

  • [Subaortic stenosis associated with perimembranous ventricular septal defect. Clinical follow-up of 36 patients].

    abstract:OBJECTIVE:To study the clinical pattern of subaortic stenosis associated with perimembranous ventricular septal defect. METHODS:From January 1979 to June 2000, 36 children with perimembranous ventricular septal defect and fixed subaortic stenosis were followed-up regarding anatomic characteristics, evolvement, and cli...

    journal_title:Arquivos brasileiros de cardiologia

    pub_type: 杂志文章

    doi:10.1590/s0066-782x2005000200002

    authors: Horta Mda G,Faria CA,Rezende DF,Masci TL,Rabelo CC,Katina T,Oliveira Md,Oliveira LP

    更新日期:2005-02-01 00:00:00

  • Prognostic value of the collagen volume fraction in hypertrophic cardiomyopathy.

    abstract:BACKGROUND:In hypertrophic cardiomyopathy (HCM), interstitial myocardial fibrosis is an important histological modification that has been associated with sudden death and evolution toward myocardial dilation. OBJECTIVE:To prospectively evaluate the prognostic value of the collagen volume fraction in HCM. METHODS:An e...

    journal_title:Arquivos brasileiros de cardiologia

    pub_type: 杂志文章

    doi:10.1590/s0066-782x2009000300010

    authors: Arteaga E,de Araújo AQ,Bernstein M,Ramires FJ,Ianni BM,Fernandes F,Mady C

    更新日期:2009-03-01 00:00:00

  • Heart Transplantation for Peripartum Cardiomyopathy: A Single-Center Experience.

    abstract:BACKGROUND:Peripartum cardiomyopathy is an idiopathic disorder defined by the occurrence of acute heart failure during late pregnancy or post-partum period in the absence of any other definable cause. Its clinical course is variable and severe cases might require heart transplantation. OBJECTIVE:To investigate long-te...

    journal_title:Arquivos brasileiros de cardiologia

    pub_type: 杂志文章

    doi:10.5935/abc.20180014

    authors: Bouabdallaoui N,Demondion P,Maréchaux S,Varnous S,Lebreton G,Mouquet F,Leprince P

    更新日期:2018-02-01 00:00:00

  • Immune-inflammatory activation in heart failure.

    abstract::Despite being relatively recent, a growing and significant accumulation of experimental and clinical evidence has been observed that points to a gradual state of immune-inflammatory activation in patients with heart failure (HF). High levels of several cytokines are found in the circulation and cardiac muscle of indiv...

    journal_title:Arquivos brasileiros de cardiologia

    pub_type: 杂志文章,评审

    doi:10.1590/s0066-782x2007001500009

    authors: Candia AM,Villacorta H Jr,Mesquita ET

    更新日期:2007-09-01 00:00:00

  • Multivessel percutaneous treatment of Takayasu arteritis.

    abstract::We report the case of a female patient with obstructive lesions in the right and left carotid, right renal, left subclavian and left common iliac arteries which were percutaneously treated. ...

    journal_title:Arquivos brasileiros de cardiologia

    pub_type: 杂志文章

    doi:10.1590/s0066-782x2006001800024

    authors: Tumelero RT,Teixeira JC,Duda NT,Tognon AP,Rossato M

    更新日期:2006-11-01 00:00:00

  • [Reproducibility of head-up tilt test in patients with neurocardiogenic syncope].

    abstract:PURPOSE:In order to identify the reproducibility of head-up tilt test, a second test one week later in 22 patients with a positive first test, was performed. METHODS:The test was performed in a fasting state during the morning. The heart rate and blood pressure were monitored during 20 minutes in the supine position a...

    journal_title:Arquivos brasileiros de cardiologia

    pub_type: 杂志文章

    doi:

    authors: Hachul D,Sosa EA,Consolim F,Magalhães L,Scanavacca M,Martinelli M,Bellotti G,Pileggi F

    更新日期:1994-05-01 00:00:00

  • Hypomethylation of Interleukin-6 Promoter is Associated with the Risk of Coronary Heart Disease.

    abstract:BACKGROUND:Interleukin-6 (IL-6) is implicated in the pathogenesis of coronary heart disease (CHD), and IL-6 expression has associated with reduced DNA methylation of its gene promoter. However, there are no data on IL-6 promoter methylation and the risk of CHD. OBJECTIVE:To examine whether IL-6 promoter methylation me...

    journal_title:Arquivos brasileiros de cardiologia

    pub_type: 杂志文章

    doi:10.5935/abc.20160124

    authors: Zuo HP,Guo YY,Che L,Wu XZ

    更新日期:2016-08-01 00:00:00

  • Angiotensin-Converting Enzyme ID Polymorphism in Patients with Heart Failure Secondary to Chagas Disease.

    abstract:BACKGROUND:Changes in the angiotensin-converting enzyme (ACE) gene may contribute to the increase in blood pressure and consequently to the onset of heart failure (HF). The role of polymorphism is very controversial, and its identification in patients with HF secondary to Chagas disease in the Brazilian population is r...

    journal_title:Arquivos brasileiros de cardiologia

    pub_type: 杂志文章

    doi:10.5935/abc.20170137

    authors: Silva SJD,Rassi S,Pereira ADC

    更新日期:2017-10-01 00:00:00

  • Multiple arterial anomalies in the newborn infant. Echocardiographic and angiographic diagnosis.

    abstract::Multiple arterial anomalies characterized by tortuosity and rolling of the pulmonary arteries and aorta were diagnosed on echocardiography in an asymptomatic newborn infant with a phenotype suggesting Ehlers-Danlos syndrome. These changes were later confirmed on angiography, which also showed peripheral vascular abnor...

    journal_title:Arquivos brasileiros de cardiologia

    pub_type: 杂志文章

    doi:10.1590/s0066-782x2000000800006

    authors: Rivera IR,Gomes L,Moisés VA,Silva CC,Andrade JL,Carvalho AC

    更新日期:2000-08-01 00:00:00

  • Fatal pulmonary embolism in hospitalized patients. Clinical diagnosis versus pathological confirmation.

    abstract::OBJECTIVE - To assess the incidence of fatal pulmonary embolism (FPE), the accuracy of clinical diagnosis, and the profile of patients who suffered an FPE in a tertiary University Hospital. METHODS - Analysis of the records of 3,890 autopsies performed at the Department of General Pathology from January 1980 to Decemb...

    journal_title:Arquivos brasileiros de cardiologia

    pub_type: 杂志文章

    doi:10.1590/s0066-782x1999000900001

    authors: Mesquita CT,Morandi Júnior JL,Perrone FT,Oliveira Cd,Barreira LJ,Nascimento SS,Pareto Júnior RC,Mesquita ET

    更新日期:1999-09-01 00:00:00

  • Development and validation of the Brazilian Portuguese version of the Cardiac Rehabilitation Barriers Scale.

    abstract:BACKGROUND:Cardiovascular diseases show high incidence and prevalence in Brazil; however, participation in Cardiac Rehabilitation (CR) is limited and has been poorly investigated in the country. The Cardiac Rehabilitation Barriers Scale (CRBS) was developed to assess the barriers to participation and adherence to CR. ...

    journal_title:Arquivos brasileiros de cardiologia

    pub_type: 杂志文章

    doi:10.1590/s0066-782x2012005000025

    authors: Ghisi GL,Santos RZ,Schveitzer V,Barros AL,Recchia TL,Oh P,Benetti M,Grace SL

    更新日期:2012-04-01 00:00:00

  • Hyperkalemia during spironolactone use in patients with decompensated heart failure.

    abstract:BACKGROUND:The incidence of hyperkalemia related to spironolactone use is low in stable heart failure; however, it has not been studied during decompensation. OBJECTIVE:To evaluate the influence of spironolactone on serum potassium in decompensated heart failure (HF). METHODS:In a cohort study, patients that had been...

    journal_title:Arquivos brasileiros de cardiologia

    pub_type: 杂志文章

    doi:10.1590/s0066-782x2008001500009

    authors: Lima MV,Ochiai ME,Cardoso JN,Morgado PC,Munhoz RT,Barretto AC

    更新日期:2008-09-01 00:00:00

  • [Acute occlusion after coronary angioplasty. Early management and late course].

    abstract:PURPOSE:Assess the efficacy of the different strategies employed in the management of acute closure and verify the late prognosis of patients who develop this complication. METHODS:From january 1987, through December 1990, 2315 consecutive patients underwent percutaneous transluminal coronary angioplasty (PTCA) in our...

    journal_title:Arquivos brasileiros de cardiologia

    pub_type: 杂志文章

    doi:

    authors: Nunes GL,Sousa AG,Tanajura LF,Cano MN,Maldonado G,Feres F,Mattos LA,Pinto IM,Sousa JE

    更新日期:1993-06-01 00:00:00

  • Comparison of diagnostic criteria for acute kidney injury in cardiac surgery.

    abstract:BACKGROUND:There is considerable controversy regarding the diagnosis of Acute Kidney Injury (AKI), and there are over 30 different definitions. OBJECTIVE:To evaluate the incidence and risk factors for the development of AKI following cardiac surgery according to the RIFLE, AKIN and KDIGO criteria, and compare the prog...

    journal_title:Arquivos brasileiros de cardiologia

    pub_type: 杂志文章

    doi:10.5935/abc.20130115

    authors: Sampaio MC,Máximo CA,Montenegro CM,Mota DM,Fernandes TR,Bianco AC,Amodeo C,Cordeiro AC

    更新日期:2013-07-01 00:00:00

  • Characterization of the in vivo cardiac electrophysiologic effects of high-dose cocaine in closed-chest, anesthetized dogs with normal hearts.

    abstract:OBJECTIVE:To characterize the cardiac electrophysiologic effects of cocaine. METHODS:In 8 dogs (9-13 kg), electrophysiologic parameters and programmed stimulation were undertaken using transvenous catheters at baseline, and after cocaine intravenous infusion (12 mg/kg bolus followed by 0.22 mg/kg/min for 25 minutes). ...

    journal_title:Arquivos brasileiros de cardiologia

    pub_type: 杂志文章

    doi:10.1590/s0066-782x2003000900002

    authors: Fenelon G,Uchoa J,Otobone JR,Reis M,do Amaral JL,de Paola AA

    更新日期:2003-07-01 00:00:00

  • Therapeutic inertia and control of high blood pressure in primary health care units.

    abstract:BACKGROUND:The importance of adequate management and control of high blood pressure (HBP). OBJECTIVE:To estimate the prevalence of hypertension control and therapeutic inertia among adults treated at primary health care units (PHCU) in the city of Joinville, as well as the associated factors. METHODS:A cross-sectiona...

    journal_title:Arquivos brasileiros de cardiologia

    pub_type: 杂志文章

    doi:10.1590/s0066-782x2010005000095

    authors: Hoepfner C,Franco SC

    更新日期:2010-08-01 00:00:00

  • Broken-heart syndrome (Takotsubo syndrome).

    abstract::Stress-induced cardiomyopathy, also know as reversible left ventricular apical ballooning, " Broken-Heart" syndrome, and in Japan, Takotsubo, is characterized by the presence of a transient left ventricular dyskinetic movement of the anterior wall of with hypercontraction of the ventricular basilar segments precipitat...

    journal_title:Arquivos brasileiros de cardiologia

    pub_type: 杂志文章

    doi:10.1590/s0066-782x2008000100011

    authors: Lemos AE,Junior Araújo AL,Lemos MT,Belém Lde S,Vasconcelos Filho FJ,Barros RB

    更新日期:2008-01-01 00:00:00

  • Contribution of the electrophysiological and anatomical analysis of the atypical atrioventricular nodal tachycardia circuit.

    abstract:OBJECTIVES:To analyze retrograde conduction during junctional ectopic tachycardia (JET) episodes and investigate the existence of a relationship between the presence of a retrograde block and the risk of atrioventricular block (AVB) development during radiofrequency ablation procedures in patients with nodal atrioventr...

    journal_title:Arquivos brasileiros de cardiologia

    pub_type: 杂志文章

    doi:10.1590/s0066-782x2007000200003

    authors: Silva MS,Sá RL,Fagundes ML,Cruz Filho FE,Arantes LB,Boghossian S,de Almeida AM,Fagundes RL,Romeo Filho LJ

    更新日期:2007-02-01 00:00:00

  • Impact of nutritional counseling in reducing serum cholesterol in public health service patients.

    abstract:OBJECTIVE:To assess the impact of nutritional attention on the lipid profile and nutritional status of hypercholesterolemic patients attended in health centers of Belo Horizonte. METHODS:Using nutritional attendance patient record cards from two health units, the evolution of the lipid profile and the nutritional stat...

    journal_title:Arquivos brasileiros de cardiologia

    pub_type: 杂志文章

    doi:10.1590/s0066-782x2003000200005

    authors: Batista Mda C,Franceschini Sdo C

    更新日期:2003-02-01 00:00:00

  • Evaluation of the medical care of patients with hypertension in an emergency department and in ambulatory hypertension unit.

    abstract:OBJECTIVE:To evaluate the characteristics of the patients receiving medical care in the Ambulatory of Hypertension of the Emergency Department, Division of Cardiology, and in the Emergency Unit of the Clinical Hospital of the Ribeirão Preto Medical School. METHODS:Using a protocol, we compared the care of the same hyp...

    journal_title:Arquivos brasileiros de cardiologia

    pub_type: 杂志文章,多中心研究

    doi:10.1590/s0066-782x2002000200003

    authors: Nobre F,Chauchar F,Viana JM,Pereira GJ,Lima NK

    更新日期:2002-02-01 00:00:00

  • Recurrence of atrial septal defect in three generations.

    abstract::Beginning with a patient presenting with an atrial septal defect (ASD) of the secundum type, the genealogy was identified in four affected individuals who belonged to three successive generations of the same family. The defects were visually confirmed in all individuals and were found to be anatomically similar. No ot...

    journal_title:Arquivos brasileiros de cardiologia

    pub_type: 杂志文章

    doi:10.1590/s0066-782x1999000800009

    authors: Ferreira C,Farah LM,Póvoa RM,Luna Filho B,Costa A,Ferreira Filho C

    更新日期:1999-08-01 00:00:00

  • [Double origin of anterior descending artery--from the left and right coronary arteries--associated with anomalous origin of the circumflex artery].

    abstract::A 65 year-old white man, with typical angina pectoris, underwent coronary angiography that showed dual left anterior descending artery (LAD), originating from the right coronary artery (RCA), associated with anomalous origin of the left circumflex artery (LCX) also from the RCA. This an extremely rare coronary artery ...

    journal_title:Arquivos brasileiros de cardiologia

    pub_type: 杂志文章

    doi:

    authors: Bastos Lde C,Ariê S,Martins JF,de Almeida RS,Jorge AC,Kahrbek T,Ferreira VL,Pereira FL

    更新日期:1996-12-01 00:00:00

  • New percutaneous techniques for perforating the pulmonary valve in pulmonary atresia with intact ventricular septum.

    abstract::We report new percutaneous techniques for perforating the pulmonary valve in pulmonary atresia with intact ventricular septum, in 3 newborns who had this birth defect. There was mild to moderate hypoplastic right ventricle, a patent infundibulum, and no coronary-cavitary communications. We succeeded in all cases, and ...

    journal_title:Arquivos brasileiros de cardiologia

    pub_type: 杂志文章

    doi:10.1590/s0066-782x2001001100008

    authors: Pedra CA,de Sousa LN,Pedra SR,Ferreira WP,Braga SL,Esteves CA,Santana MV,Sousa JE,Fontes VF

    更新日期:2001-11-01 00:00:00

  • Revision of the Sokolow-Lyon-Rappaport and cornell voltage criteria for left ventricular hypertrophy.

    abstract:BACKGROUND:Electrocardiographically-detected left ventricular hypertrophy (LVH) is a strong predictor of cardiovascular morbidity and mortality. OBJECTIVE:To assess the performance of the Sokolow-Lyon-Rappaport (SLR) and Cornell voltage criteria in a population sample regarding the diagnosis of LVH on echocardiogram (...

    journal_title:Arquivos brasileiros de cardiologia

    pub_type: 杂志文章

    doi:10.1590/s0066-782x2008000100008

    authors: Rodrigues SL,D'Angelo L,Pereira AC,Krieger JE,Mill JG

    更新日期:2008-01-01 00:00:00

  • [Myocardial lesions after snake bites by the Crotalus durissus terrificus species (rattlesnake). A case report].

    abstract::Extensive and severe myocardial lesions are reported in a patient who died due to snakebite (Crotalus Durissus Terrificus). These lesions are documented by clinical, electrocardiographic, enzymatic and histological evidences. The main pathological features are represented by sarcoplasmatic vacuoles, densely clumped my...

    journal_title:Arquivos brasileiros de cardiologia

    pub_type: 杂志文章

    doi:

    authors: de Siqueira JE,Higuchi Mde L,Nabut N,Lose A,Souza JK,Nakashima M

    更新日期:1990-05-01 00:00:00

  • Dietary interventions and blood pressure in Latin America - systematic review and meta-analysis.

    abstract:BACKGROUND:High blood pressure is the major risk factor for cardiovascular disease. Low blood pressure control rates in Latin American populations emphasize the need for gathering evidence on effective therapies. OBJECTIVE:To evaluate the effects of dietary interventions on blood pressure in Latin American populations...

    journal_title:Arquivos brasileiros de cardiologia

    pub_type: 杂志文章,meta分析,评审

    doi:10.5935/abc.20140037

    authors: Mazzaro CC,Klostermann FC,Erbano BO,Schio NA,Guarita-Souza LC,Olandoski M,Faria-Neto JR,Baena CP

    更新日期:2014-04-01 00:00:00