The effect of short-term immunotherapy with Pollinex on anti-IgE and antigen-induced histamine release from sensitive human basophils.

Abstract:

:Anti-IgE and antigen-induced histamine release from basophils isolated from 30 atopic patients sensitive to grass pollen allergens was evaluated. The studies were made before and after short-term immunotherapy with glutaraldehyde-pollen-tyrosine adsorbate (Pollinex). It was shown, that after immunotherapy a significant drop in anti-IgE and specific antigen-induced histamine release from isolated basophils occurs. The investigations confirm that the diminution of the target cell sensitivity and releasability may be one of the effects of specific immunotherapy.

authors

Chyrek-Borowska S,Kuczewska B,Hofman J,Szymański W,Lukaszewicz D

subject

Has Abstract

pub_date

1985-01-01 00:00:00

pages

777-82

issue

6

eissn

0004-069X

issn

1661-4917

journal_volume

33

pub_type

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