Abstract：
:Polychlorinated biphenyls (PCB) were added to the diets of mice at different concentrations. Mice fed these diets were given a sc or oral doses of 109Cd. The uptake and excretion of Cd was followed by whole-body counting. The gastrointestinal absorption of Cd after an oral dose of 109Cd was less in animals fed on 66 ppm PCB diet, compared with a control group, and the body elimination of Cd was faster. In the liver, the amount of Cd was reduced by dietary PCB exposure, after both oral and sc administration of 109Cd, and the data suggest a faster transport of Cd from liver to kidneys in PCB-exposed animals than in controls. The mobilized liver Cd was not quantitatively recovered in the kidneys, thus increased urinary excretion due to PCB exposure may have taken place. Histological examination of the livers revealed a dose-dependent induction of liver changes characterized by centrilobular enlargement of liver cells and centrilobular focal necroses. In four of eight livers from animals fed 200 ppm PCB for 32 weeks there were five liver cell tumors with cytological signs of malignancy. In the control group and in groups fed lower doses of PCB (10-100 ppm) no such tumors were found among 28 animals. The results support observations made with agents inducing acute liver damage, that liver damage increases the rate of redistribution of cadmium from the liver to the kidney.
journal_name
Environ Resjournal_title
Environmental researchauthors
Andersen O,Lindegaard P,Unger M,Nordberg GFdoi
10.1016/0013-9351(85)90086-6subject
Has Abstractpub_date
1985-12-01 00:00:00pages
213-24issue
2eissn
0013-9351issn
1096-0953pii
0013-9351(85)90086-6journal_volume
38pub_type
杂志文章abstract：BACKGROUND:Dairy working increases the prevalence of lower airway respiratory diseases, especially COPD and asthma. Epidemiological studies have reported that chronic inhalation of organic dusts released during specific daily tasks could represent a major risk factor for development of these pathologies in dairy worker...
journal_title：Environmental research
pub_type： 杂志文章
doi：10.1016/j.envres.2017.07.025
更新日期：2017-10-01 00:00:00
abstract：:Children may be more vulnerable to the combined interactions of chemical and non-chemical stressors from their built, natural, and social environments when compared to adults. Attention deficit/hyperactivity disorder (ADHD) is the most commonly diagnosed childhood neurodevelopmental disorder and is considered a major ...
journal_title：Environmental research
pub_type： 杂志文章,meta分析
doi：10.1016/j.envres.2019.108884
更新日期：2020-01-01 00:00:00
abstract：:The stability of the linings of packaging that is in contact with the goods stored has been of major concern during decades of the development of packaging materials. In this work, an attempt was undertaken to assess the applicability of using two bioassays (Microtox® and XenoScreen YES/YAS) in estimating the stabilit...
journal_title：Environmental research
pub_type： 杂志文章
doi：10.1016/j.envres.2018.05.004
更新日期：2018-08-01 00:00:00
abstract：:Chronic exposure to hydrogen sulfide (H(2)S) in the parts per billion-parts per million range occurs in the population of Rotorua, a city built upon an actively degassing geothermal field in the Taupo Volcanic Zone, New Zealand. H(2)S is acutely toxic at high concentrations but little is understood of the health effec...
journal_title：Environmental research
pub_type： 杂志文章
doi：10.1016/j.envres.2005.08.006
更新日期：2006-06-01 00:00:00
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journal_title：Environmental research
pub_type： 杂志文章
doi：10.1006/enrs.1993.1039
更新日期：1993-02-01 00:00:00
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journal_title：Environmental research
pub_type： 杂志文章
doi：10.1016/s0013-9351(88)80014-8
更新日期：1988-02-01 00:00:00
abstract：BACKGROUND:Dichlorodiphenyltrichloroethane (DDT) and polychlorinated biphenyls (PCBs) are persistent organochlorine compounds bioaccumulating in human tissues. Body burden of organochlorines may be influenced by individual characteristics such as age, weight variations, breastfeeding, dietary habits and place of reside...
journal_title：Environmental research
pub_type： 杂志文章
doi：10.1016/j.envres.2011.06.001
更新日期：2011-08-01 00:00:00
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journal_title：Environmental research
pub_type： 杂志文章
doi：10.1016/j.envres.2007.01.012
更新日期：2007-10-01 00:00:00
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journal_title：Environmental research
pub_type： 杂志文章
doi：10.1016/j.envres.2014.07.030
更新日期：2014-11-01 00:00:00
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journal_title：Environmental research
pub_type： 杂志文章
doi：10.1016/j.envres.2016.04.030
更新日期：2016-07-01 00:00:00
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journal_title：Environmental research
pub_type： 杂志文章
doi：10.1016/j.envres.2017.09.009
更新日期：2018-01-01 00:00:00
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journal_title：Environmental research
pub_type： 杂志文章
doi：10.1016/j.envres.2008.06.006
更新日期：2008-11-01 00:00:00
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journal_title：Environmental research
pub_type： 杂志文章
doi：10.1016/j.envres.2005.08.008
更新日期：2006-05-01 00:00:00
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journal_title：Environmental research
pub_type： 杂志文章
doi：10.1016/j.envres.2018.12.058
更新日期：2019-03-01 00:00:00
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journal_title：Environmental research
pub_type： 杂志文章
doi：10.1016/j.envres.2017.07.035
更新日期：2017-10-01 00:00:00
abstract：:Soybean plants were grown for 90 days and spinach plants for 64 days in a mixture of sterilized greenhouse soil and sand containing 10 ppm pentachlorophenol. All plant parts and soil samples were extracted and separated into nonpolar and polar fractions. Major nonpolar and polar metabolites were identified by gas-liqu...
journal_title：Environmental research
pub_type： 杂志文章
doi：10.1016/0013-9351(85)90053-2
更新日期：1985-06-01 00:00:00
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journal_title：Environmental research
pub_type： 杂志文章
doi：10.1016/j.envres.2011.02.003
更新日期：2011-05-01 00:00:00
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journal_title：Environmental research
pub_type： 杂志文章
doi：10.1016/j.envres.2019.108631
更新日期：2019-10-01 00:00:00
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journal_title：Environmental research
pub_type： 杂志文章
doi：10.1016/s0013-9351(86)80006-8
更新日期：1986-02-01 00:00:00
abstract：:Patterns of mortality in 11 air-conditioned and 9 un-air-conditioned nursing homes in New York City have been investigated to determine the impacts of heat waves on nursing home occupants and the efficacy of air conditioning in reducing these impacts. During each of four heat waves in 1972 and 1973, the number of deat...
journal_title：Environmental research
pub_type： 杂志文章
doi：10.1016/0013-9351(78)90065-8
更新日期：1978-08-01 00:00:00
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journal_title：Environmental research
pub_type： 杂志文章,评审
doi：10.1016/j.envres.2018.02.037
更新日期：2018-07-01 00:00:00
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journal_title：Environmental research
pub_type： 杂志文章
doi：10.1016/j.envres.2014.03.010
更新日期：2014-05-01 00:00:00
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journal_title：Environmental research
pub_type： 杂志文章
doi：10.1016/s0013-9351(03)00111-7
更新日期：2004-01-01 00:00:00
abstract：:The effects of nickel chloride on the cellular and humoral immune responses of mice were studied. A single intramuscular injection of nickel chloride (18.3 mg/kg) caused a significant involution of the thymus within 2 days following treatment. Significant reductions in the in vitro mitogen-stimulated response of lymph...
journal_title：Environmental research
pub_type： 杂志文章
doi：10.1016/0013-9351(84)90039-2
更新日期：1984-04-01 00:00:00
abstract：:There is mounting evidence that maternal exposure to ambient air pollution during pregnancy is associated with adverse birth outcomes. We examined birth weight and small for gestational age (SGA <10th percentile for age and gender) among 26,617 singleton full-term births in Brisbane, Australia (July 2000-June 2003), i...
journal_title：Environmental research
pub_type： 杂志文章
doi：10.1016/j.envres.2006.06.010
更新日期：2007-03-01 00:00:00
abstract：:In 1992, the U.S. Congress passed the Residential Lead-Based Paint Hazard Reduction Act, which requires the promulgation of health-based dust lead and soil lead standards for residential dwellings to prevent undue lead exposure in children. Unfortunately, the levels of lead in house dust and soil that are associated w...
journal_title：Environmental research
pub_type： 杂志文章,meta分析
doi：10.1006/enrs.1998.3859
更新日期：1998-10-01 00:00:00
abstract：BACKGROUND:Heightened blood lead levels (BLL) are associated with cognitive deficiencies and adverse behavioral outcomes. Lead-contaminated house dust is the primary source of exposure in U.S. children, and evidence suggests that even background (low-level) exposure has negative consequences. Identifying sources of bac...
journal_title：Environmental research
pub_type： 杂志文章
doi：10.1016/j.envres.2018.12.069
更新日期：2019-03-01 00:00:00
abstract：:Concentrated human milk (HM-concentrate) can be obtained from the simple and inexpensive method of donated breast milk direct lyophilization. A previous study reported that HM-concentrate contains the adequate amount of main macro- and micronutrients for use as a nutritional resource for preterm infants with very low ...
journal_title：Environmental research
pub_type： 杂志文章
doi：10.1016/j.envres.2020.109733
更新日期：2020-09-01 00:00:00
abstract：:The effects of low-level lead exposure on neuropsychological status in the United States (US) general adult population have been reported, and the relationship between neuropsychiatric dysfunction and health risk behaviors including substance use and sexual risk taking is well established. However, the potential influ...
journal_title：Environmental research
pub_type： 杂志文章
doi：10.1016/j.envres.2014.05.037
更新日期：2014-11-01 00:00:00
abstract：:The effects of cadmium on the immune system have been extensively studied, although relatively little is known about the nature of the interaction between cadmium and lymphocytes. We describe studies that examine the uptake and subcellular distribution of cadmium in resting and mitogen-activated mouse splenic lymphocy...
journal_title：Environmental research
pub_type： 杂志文章
doi：10.1016/s0013-9351(89)80071-4
更新日期：1989-08-01 00:00:00
