Postnatal development of the endothelial system of the rat cerebellum using immunohistochemical techniques.

Abstract:

:The development of the endothelial system of the rat cerebellum was studied by immunohistochemical techniques with two antibodies specific of two membrane antigens characteristic of 'mature' endothelial cells. It appears that the maturation of endothelial cells is very late in the rat cerebellum. This absence of a fully endothelial barrier in cerebella of young rats could explain the extreme sensitivity of this part of the central nervous system to various agents.

journal_name

Brain Res

journal_title

Brain research

authors

Zanetta JP,Dontenwill M,Bricca G

doi

10.1016/0165-3806(85)90149-x

subject

Has Abstract

pub_date

1985-01-01 00:00:00

pages

253-7

issue

1-2

eissn

0006-8993

issn

1872-6240

journal_volume

349

pub_type

杂志文章
  • Projection patterns from the amygdaloid nuclear complex to subdivisions of the dorsal raphe nucleus in the rat.

    abstract::The goal of the present study was to identify the projection from the subdivisions of the amygdaloid nuclear complex to specified subregions of the dorsal raphe (DR) nucleus and to attempt to compare the density of amygdaloid input to the DR with that of inputs from other limbic structures. Use of a retrograde tracer,...

    journal_title:Brain research

    pub_type: 杂志文章

    doi:10.1016/j.brainres.2007.01.081

    authors: Lee HS,Eum YJ,Jo SM,Waterhouse BD

    更新日期:2007-04-27 00:00:00

  • Prostaglandin E2 may induce hyperthermia through EP1 receptor in the anterior wall of the third ventricle and neighboring preoptic regions.

    abstract::We have previously reported that intracerebroventricular injection of prostaglandin E2 (PGE2) induces hyperthermia possibly through EP1 receptors in the rat. In the present study, to determine the sites in the brain where PGE2 induces hyperthermia through EP1 receptors, we microinjected an EP1 receptor agonist, 17-phe...

    journal_title:Brain research

    pub_type: 杂志文章

    doi:10.1016/s0006-8993(97)00562-3

    authors: Oka K,Oka T,Hori T

    更新日期:1997-08-29 00:00:00

  • Ultrastructural observations of non-selective effects of ricin treatment (RCA-120) in the rat dorsal root ganglion.

    abstract::The effects of ricin (RCA-120) on non-injected dorsal root ganglion (DRG) cells, sharing the same DRG as the injected ones, were studied after ricin injections into the tibial nerve and B-HRP injections into the peroneal nerve. Numerous DRG cells containing B-HRP reaction product and exhibiting signs of advanced degen...

    journal_title:Brain research

    pub_type: 杂志文章

    doi:10.1016/0006-8993(90)90561-o

    authors: Rivero-Melián C,Arvidsson J

    更新日期:1990-02-19 00:00:00

  • Modulatory and direct effects of propofol on recombinant GABAA receptors expressed in xenopus oocytes: influence of alpha- and gamma2-subunits.

    abstract::Propofol (2,6-diisopropylphenol) is an intravenous general anaesthetic which can directly activate and positively modulate the GABAA receptor. The effects of propofol on human recombinant GABAA receptors were studied in Xenopus oocytes expressing either alpha1beta2, alpha1beta2gamma2L, or alpha2beta2gamma2L receptor i...

    journal_title:Brain research

    pub_type: 杂志文章

    doi:10.1016/s0006-8993(97)01334-6

    authors: Lam DW,Reynolds JN

    更新日期:1998-02-16 00:00:00

  • Human Thy-1: expression on the cell surface of neuronal and glial cells.

    abstract::The Thy-1 antigen is a cell surface glycoprotein found in neural tissue of all mammalian species so far studied. The distribution and amount of this antigen has been measured on 4 human neuronal and 2 neuroglial cell lines and on fresh tumour cells of neuronal origin. In 3 out of 4 neuronal lines (LAN-1, TR14, CHP 212...

    journal_title:Brain research

    pub_type: 杂志文章

    doi:10.1016/0006-8993(82)90727-2

    authors: Kemshead JT,Ritter MA,Cotmore SF,Greaves MF

    更新日期:1982-03-25 00:00:00

  • Down-regulation of Na channel expression by A23187 in N1E-115 neuroblastoma cells.

    abstract::Growth of cultured N1E-115 neuroblastoma cells in 1 microM A23187 for 2 days to elevate internal Ca reduced both membrane Na current and the transient, but not steady state, component of outward K current. Na channel mRNA abundance was reduced by an average value of 45% without effect on Kv3.1. Increases in internal C...

    journal_title:Brain research

    pub_type: 杂志文章

    doi:10.1016/0006-8993(95)01340-7

    authors: Hirsh JK,Quandt FN

    更新日期:1996-01-15 00:00:00

  • Extracellular serotonin levels in the medullary reticular formation during normal sleep and after REM sleep deprivation.

    abstract::Rapid eye movement (REM) sleep is hypothesized to result from the activity of REM sleep-generating and REM sleep-inhibiting neurons. The serotoninergic (5-HT) neurons of the dorsal raphe nucleus (DRN) represents one such population of REM-sleep inhibiting neurons since they are silent during REM sleep. Consistent with...

    journal_title:Brain research

    pub_type: 杂志文章

    doi:10.1016/s0006-8993(01)03209-7

    authors: Blanco-Centurion CA,Salin-Pascual RJ

    更新日期:2001-12-27 00:00:00

  • Adrenaline concentration and turnover in the arcuate nucleus and median eminence during the critical period in the rat.

    abstract::Previous work has shown a relatively high turnover of adrenaline in the mediobasal hypothalamus during the critical period (15.00-17.00 h) of the proestrous rat. We now report that this high level of adrenergic activity can be detected in the median eminence (turnover rate 1.62 +/- 0.36 pg/micrograms protein/h) rather...

    journal_title:Brain research

    pub_type: 杂志文章

    doi:10.1016/0006-8993(84)90307-x

    authors: Sheaves R,Warburton E,Laynes R,Mackinnon P

    更新日期:1984-12-10 00:00:00

  • Excitatory amino acid receptor regulation after subthalamic nucleus lesions in the rat.

    abstract::The subthalamic nucleus plays a pivotal role in the regulation of basal ganglia output. Recent electrophysiologic, lesion and immunocytochemical studies suggest that the subthalamic nucleus uses an excitatory amino acid as a neurotransmitter. After complete ablation of the subthalamic nucleus, we have examined the NMD...

    journal_title:Brain research

    pub_type: 杂志文章

    doi:10.1016/0006-8993(93)90257-n

    authors: Price RH Jr,Hollingsworth Z,Young AB,Penney JB Jr

    更新日期:1993-01-29 00:00:00

  • Excitotoxic hippocampal neuron loss following sustained electrical stimulation of the perforant pathway in the mouse.

    abstract::Prolonged electrical stimulation of the perforant pathway in the rat evokes epileptiform discharges in dentate granule cells and irreversibly damages hilar neurons. In this in vivo study, we demonstrate that similar perforant path stimulation in C57Bl/6 mice causes the same pattern of hippocampal neuron loss. Therefor...

    journal_title:Brain research

    pub_type: 杂志文章

    doi:10.1016/j.brainres.2006.02.055

    authors: Kienzler F,Jedlicka P,Vuksic M,Deller T,Schwarzacher SW

    更新日期:2006-04-26 00:00:00

  • Behavioral effects of CD40-CD40L pathway disruption in aged PSAPP mice.

    abstract::We have shown that, when an amyloid-beta peptide (Abeta) overproducing transgenic mouse model (PSAPP) of Alzheimer's disease (AD) is treated with a depleting antibody against CD40L, it causes marked attenuation of Abeta pathology associated with decreased amyloidogenic processing of amyloid precursor protein (APP) and...

    journal_title:Brain research

    pub_type: 杂志文章

    doi:10.1016/j.brainres.2004.05.004

    authors: Todd Roach J,Volmar CH,Dwivedi S,Town T,Crescentini R,Crawford F,Tan J,Mullan M

    更新日期:2004-07-23 00:00:00

  • Dopamine receptor gene expression in human amygdaloid nuclei: elevated D4 receptor mRNA in major depression.

    abstract::Previous findings from this laboratory demonstrating changes in dopamine (DA) transporter and D2 receptors in the amygdaloid complex of subjects with major depression indicate that disruption of dopamine neurotransmission to the amygdala may contribute to behavioral symptoms associated with depression. Quantitative re...

    journal_title:Brain research

    pub_type: 杂志文章

    doi:10.1016/j.brainres.2008.02.009

    authors: Xiang L,Szebeni K,Szebeni A,Klimek V,Stockmeier CA,Karolewicz B,Kalbfleisch J,Ordway GA

    更新日期:2008-05-01 00:00:00

  • Acute estradiol application increases inward and decreases outward whole-cell currents of neurons in rat hypothalamic ventromedial nucleus.

    abstract::Acute estradiol (E2) can potentiate the excitatory responses of hypothalamic ventromedial nucleus (VMN) neurons to neurotransmitters. To investigate the mechanism(s) underlying the potentiation, the whole-cell patch voltage clamp technique was used to study VMN neurons in hypothalamic slices prepared from female juven...

    journal_title:Brain research

    pub_type: 杂志文章

    doi:10.1016/j.brainres.2006.07.104

    authors: Kow LM,Devidze N,Pataky S,Shibuya I,Pfaff DW

    更新日期:2006-10-20 00:00:00

  • Insulin-stimulated translocation of GLUT4 to the plasma membrane in rat hippocampus is PI3-kinase dependent.

    abstract::In the central nervous system (CNS) insulin mediates a variety of effects including feeding, metabolism and cognition. The cognitive enhancing effects of insulin are proposed to be mediated through activation of insulin receptors in the hippocampus, an important integration center for learning and memory in the mammal...

    journal_title:Brain research

    pub_type: 杂志文章

    doi:10.1016/j.brainres.2009.08.005

    authors: Grillo CA,Piroli GG,Hendry RM,Reagan LP

    更新日期:2009-11-03 00:00:00

  • Alterations of adenosine A1 receptors in morphine dependence.

    abstract::The possibility that central adenosine A1 and A2a receptors mediate opiate dependence was examined in morphine-treated mice using radioligand binding methods. Mice treated with morphine for 72 h demonstrated significant increases in naloxone precipitated abstinence behaviors of jumping, wet-dog shakes, teeth chatterin...

    journal_title:Brain research

    pub_type: 杂志文章

    doi:10.1016/0006-8993(94)90990-3

    authors: Kaplan GB,Leite-Morris KA,Sears MT

    更新日期:1994-09-19 00:00:00

  • Properties of otolith-related vestibular nuclear neurons in response to bidirectional off-vertical axis rotation of the rat.

    abstract::In decerebrate rats, the responses of tilt-sensitive neurons in the lateral and descending vestibular nuclei were studied during constant velocity 10 degrees off-vertical axis rotations (OVAR) in the clockwise (VW) and counterclockwise (CCW) directions. Seventy three otolith-related units showed a sinusoidal position-...

    journal_title:Brain research

    pub_type: 杂志文章

    doi:10.1016/0006-8993(95)00687-l

    authors: Lai CH,Chan YS

    更新日期:1995-09-25 00:00:00

  • PhTx4, a new class of toxins from Phoneutria nigriventer spider venom, inhibits the glutamate uptake in rat brain synaptosomes.

    abstract::We report the characterization of a new class of glutamate uptake inhibitors isolated from Phoneutria nigriventer venom. Glutamate transport activity was assayed in rat cerebrocortical synaptosomes by using [(3)H]-L-glutamate. PhTx4 inhibited glutamate uptake in a dose dependent manner. The IC(50) value obtained was 2...

    journal_title:Brain research

    pub_type: 杂志文章

    doi:10.1016/s0006-8993(99)01472-9

    authors: Mafra RA,Figueiredo SG,Diniz CR,Cordeiro MN,Cruz JD,De Lima ME

    更新日期:1999-06-12 00:00:00

  • Autoradiographic analysis of dopamine receptor-stimulated [(35)S]GTPgammaS binding in rat striatum.

    abstract::Autoradiographic analysis of [(35)S]GTPgammaS binding was used to investigate functional activation of dopamine receptors in rat striatum. Dopamine-stimulated [(35)S]GTPgammaS binding was observed with a maximal increase of 38% over basal activity. A similar stimulatory response was obtained with the D(2) agonist quin...

    journal_title:Brain research

    pub_type: 杂志文章

    doi:10.1016/s0006-8993(00)02981-4

    authors: He L,Di Monte DA,Langston JW,Quik M

    更新日期:2000-12-01 00:00:00

  • Feeding induced by microinjections of NMDA and AMPA-kainate receptor antagonists into ventral striatal and ventral pallidal areas of the pigeon.

    abstract::The participation of glutamatergic circuits of the ventral basal ganglia in feeding-related regulatory mechanisms has been extensively indicated in primate and rodent species. In avian species, it has been shown that ICV injections of MK-801 or of CNQX increase food intake and reduce the latency of feeding initiation ...

    journal_title:Brain research

    pub_type: 杂志文章

    doi:10.1016/s0006-8993(02)04196-3

    authors: Da Silva AA,Marino-Neto J,Paschoalini MA

    更新日期:2003-03-14 00:00:00

  • Endogenous endothelin-1 initiates astrocytic growth after spinal cord injury.

    abstract::We developed a rat spinal cord injury model and investigated whether endogenous endothelin (ET)-1 plays a role in astrocytic growth after injury. Immunohistochemical study showed that the number of immature astrocytes (ACs) exhibiting strong reactivity to the monoclonal antibody, RC1, markedly increased 24 h after the...

    journal_title:Brain research

    pub_type: 杂志文章

    doi:10.1016/0006-8993(96)00524-0

    authors: Uesugi M,Kasuya Y,Hama H,Yamamoto M,Hayashi K,Masaki T,Goto K

    更新日期:1996-07-29 00:00:00

  • Long-term survival and development of dissociated parasympathetic neurons in culture.

    abstract::Ciliary ganglion neurons from chick embryo were grown in cell culture following enzymatic and mechanical dissociation. The culture conditions necessary for long-term (greater than 21 days) survival of the isolated neurons were investigated. Neurons could be cultured with and without non-neural cells by adjusting the c...

    journal_title:Brain research

    pub_type: 杂志文章

    doi:10.1016/0006-8993(80)90127-4

    authors: Tuttle JB,Suszkiw JB,Ard M

    更新日期:1980-02-03 00:00:00

  • Minocycline treatment reduces white matter damage after excitotoxic striatal injury.

    abstract::We investigated the protective effects of minocycline following white matter damage (WMD) in the rat striatum. Excitotoxic lesions were induced by N-Methyl-d-Aspartate (NMDA) microinjections and caused striatal damage, concomitant with microglial/macrophage activation. The excitotoxic lesion both damaged oligodendrocy...

    journal_title:Brain research

    pub_type: 杂志文章

    doi:10.1016/j.brainres.2010.03.007

    authors: Guimarães JS,Freire MA,Lima RR,Picanço-Diniz CW,Pereira A,Gomes-Leal W

    更新日期:2010-05-06 00:00:00

  • The interaction of extracellular H+, Na+, Ca2+ and Sr2+ on the decay of miniature end-plate currents.

    abstract::We suggested previously that increases in the extracellular [Ca2+] or [Mg2+] lengthen miniature end-plate currents (m.e.p.c.s.) because the divalent cations decrease the negative surface potential on the end-plate, and thereby increase the voltage drop within the membrane. The increased voltage drop would lengthen the...

    journal_title:Brain research

    pub_type: 杂志文章

    doi:10.1016/0006-8993(82)91065-4

    authors: Cohen I,Van der Kloot W

    更新日期:1982-06-10 00:00:00

  • Bilateral projection of functionally characterized trigeminal oralis neurons to trigeminal motoneurons in cats.

    abstract::Intracellular Neurobiotin-injections were used to label functionally identified neurons in the rostro-dorsomedial part of the trigeminal oral nucleus (Vo.r) in the cat. The labeled Vo.r neurons with the mechanoreceptive field in oral tissues innervated bilaterally either jaw-opening motoneurons or jaw-closing motoneur...

    journal_title:Brain research

    pub_type: 杂志文章

    doi:10.1016/j.brainres.2004.12.042

    authors: Yoshida A,Yamamoto M,Moritani M,Fukami H,Bae YC,Chang Z,Sugiyo S,Takemura M,Park KP,Shigenaga Y

    更新日期:2005-03-02 00:00:00

  • The effects of stimulation and lesion of raphe nuclei on luteinizing hormone release in estrogen-progesterone-treated ovariectomized rats.

    abstract::A study was made of the effects of electrochemically stimulating (ECS) and destroying the midbrain dorsal and median raphe nuclei on the estrogen-progesterone- (EP) induced surge of pituitary LH release in ovariectomized rats. ECS and lesions were produced simultaneously with anodal direct current through a chronicall...

    journal_title:Brain research

    pub_type: 杂志文章

    doi:10.1016/0006-8993(81)90006-8

    authors: Waloch M,Gilman D,Whitmoyer D,Sawyer CH

    更新日期:1981-08-03 00:00:00

  • Involvement of human left frontoparietal cortices in neural processes associated with task-switching between two sequences of skilled finger movements.

    abstract::In this study, we demonstrate the involvement of left frontoparietal cortices in neural processes for task-switching between skilled movements. Functional magnetic resonance imaging was conducted while thirty-two right-handed healthy participants performed two sequential finger-movement tasks with their left hands. On...

    journal_title:Brain research

    pub_type: 杂志文章

    doi:10.1016/j.brainres.2019.146365

    authors: Uehara S,Mizuguchi N,Hirose S,Yamamoto S,Naito E

    更新日期:2019-11-01 00:00:00

  • Genetic correlations among inbred strain sensitivities to convulsions induced by 9 convulsant drugs.

    abstract::Inbred mouse strains differed significantly in sensitivity to convulsions induced by 9 convulsant drugs administered using a timed infusion procedure. Some strains (e.g. BALB/cJ, A/J) were generally seizure-susceptible, while some were generally seizure resistant (e.g. C57BL/6J, SWR/J). However, the overall pattern of...

    journal_title:Brain research

    pub_type: 杂志文章

    doi:10.1016/0006-8993(90)90243-5

    authors: Kosobud AE,Crabbe JC

    更新日期:1990-08-27 00:00:00

  • Specificity-related suppression of responses to binary mixtures in olfactory receptors of the Colorado potato beetle.

    abstract::Responses of antennal olfactory receptors of the Colorado potato beetle (Leptinotarsa decemlineata Say) to stimulation with 5 general green odour components, i.e. cis-3-hexen-1-ol, trans-2-hexenal, cis-3-hexenyl acetate, trans-2-hexen-1-ol and 1-hexanol, were recorded extracellularly. Response spectra derived from the...

    journal_title:Brain research

    pub_type: 杂志文章

    doi:10.1016/0006-8993(88)90961-4

    authors: De Jong R,Visser JH

    更新日期:1988-04-26 00:00:00

  • Antagonistic action of diphenylhydantoin and calcium on the level of phosphorylation of particular rat and human brain proteins.

    abstract::The opposing actions of diphenylhydantoin (DPH) and calcium on the level of [32P]phosphate incorporation into particular rat and human brain proteins have been demonstrated in this study by employing the techniques of acrylamide gel electrophoresis and autoradiography. In the presence of calcium several brain proteins...

    journal_title:Brain research

    pub_type: 杂志文章

    doi:10.1016/0006-8993(77)90930-1

    authors: DeLorenzo RJ

    更新日期:1977-09-23 00:00:00

  • Distribution of osmosensitive cells in the preoptic and adjacent regions of cat brains.

    abstract::The response of neurons in the preoptic and adjacent regions of the brain to intracarotid injection of hyperosmotic solutions was studied in 22 anesthetized cats. NaCl (0.5 M) caused a brisk acceleration of frequency lasting over 100 s in 120 of 207 units (58%). Glucose (2 M) and sucrose (2 M) had similar but smaller ...

    journal_title:Brain research

    pub_type: 杂志文章

    doi:10.1016/0006-8993(85)91026-1

    authors: Hubbard JI,Mills RG,Sirett NE

    更新日期:1985-10-21 00:00:00