Abstract:
:90Y-labeled SIR-Spheres are currently used to treat patients with hepatic metastases secondary to colorectal adenocarcinoma. In general, the prescribed activity is based on empirical data collected during clinical trials. The activity of the source vial is labeled by the manufacturer as 3.0 GBq +/- 10% and is not independently verified by the end user. This technical note shows that the results of a nondestructive spectroscopic assay of a SIR-Spheres sample was 26% higher than the activity stated by the manufacturer. This difference should not impact the current empirical prescription method but may be problematic for patient-specific dosimetry applications, such as image-based dosimetry.
journal_name
Med Physjournal_title
Medical physicsauthors
Selwyn R,Micka J,DeWerd L,Nickles R,Thomadsen Bdoi
10.1118/1.2889621subject
Has Abstractpub_date
2008-04-01 00:00:00pages
1278-9issue
4eissn
0094-2405issn
2473-4209journal_volume
35pub_type
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