Occurrence of 4-hydroxyalkenals in rat tissues determined as pentafluorobenzyl oxime derivatives by gas chromatography-mass spectrometry.

abstract：:The effect of HMG1 on the transcriptional block caused by left-handed Z-form in a highly negatively supercoiled DNA was examined using a supercoiled plasmid containing a (CG)10 sequence downstream of promoters. The transcription by E. coli RNA polymerase was blocked at the boundary of alternating CG sequence in the Z-...

journal_title：Biochemical and biophysical research communications

authors： Waga S,Mizuno S,Yoshida M

更新日期：1988-05-31 00:00:00

abstract：:HMG 14 and protamine can be used to enhance intermolecular ligation of low concentrations of linear DNA. Adding HMG 14 (50 moles per mole DNA) caused 50% of blunt-ended DNA to form predominantly dimers, and all cohesive-ended DNA to form multimers (greater than 6-mer) in response to T4 ligase. Protamine was maximally ...

journal_title：Biochemical and biophysical research communications

authors： Sheflin LG,Fucile NW,Spaulding SW

更新日期：1991-01-31 00:00:00

abstract：:An increase in plasma prorenin during pregnancy suggests that prorenin might be synthesized in the ovary and the secretion of renin or prorenin may be stimulated by an ovarian steroid-mediated process. Recently, renin and angiotensinogen have been identified in human ovarian follicular fluid. However, there is conside...

journal_title：Biochemical and biophysical research communications

authors： Kim S,Shinjo M,Fukamizu A,Miyazaki H,Usuki S,Murakami K

更新日期：1987-01-15 00:00:00

abstract：:Long-term glyburide therapy has been reported to improve glucose-induced insulin secretion in patients with NIDDM. We examined the effects of glyburide on the synthesis and release of insulin and insulin gene expression in isolated islets in vitro. Incubation with glyburide (500 ng/ml) significantly increased insulin ...

journal_title：Biochemical and biophysical research communications

authors： Yamato E,Ikegami H,Tahara Y,Fukuda M,Cha T,Kawaguchi Y,Fujioka Y,Noma Y,Shima K,Ogihara T

更新日期：1994-02-28 00:00:00

abstract：:Calmodulin is phosphorylated by casein kinase II on Thr-79, Ser-81, Ser-101 and Thr-117. To determine the consensus sequences for casein kinase II in intact calmodulin, we examined casein kinase II-mediated phosphorylation of engineered calmodulins with 1-4 deletions in the central helical region (positions 81-84). To...

journal_title：Biochemical and biophysical research communications

authors： Sacks DB,Davis HW,Crimmins DL,Persechini A,McDonald JM

更新日期：1992-10-30 00:00:00

abstract：:In some v-Ha-ras-transfected cell lines, serum deprivation results in apoptosis. Clarification of the molecular mechanisms by which oncogenic Ras controls susceptibility to apoptosis may assist in the development of effective therapies against human cancer with oncogenic ras gene. In this report, we established a v-Ha...

journal_title：Biochemical and biophysical research communications

authors： Arase Y,Hiwasa T,Hasegawa R,Nomura J,Ito H,Suzuki N

更新日期：2000-01-07 00:00:00

abstract：:F(0)F(1)-ATPase within chromatophore was constructed as a biosensor (immuno-rotary biosensor) for the purpose of capturing single virus. Capture of virus was based on antibody-antigen reaction. The detection of virus based on proton flux change driven by ATP-synthesis of F(0)F(1)-ATPase, which was indicated by F1300, ...

journal_title：Biochemical and biophysical research communications

authors： Liu X,Zhang Y,Yue J,Jiang P,Zhang Z

更新日期：2006-04-21 00:00:00

abstract：:The methylcoenzyme M methylreductase reaction has an absolute requirement for 7-mercaptoheptanoylthreonine phosphate or component B, which is the active component of the intact molecule previously referred to as cytoplasmic cofactor. A hydrolytic fragment of cytoplasmic cofactor has been purified and identified as uri...

journal_title：Biochemical and biophysical research communications

authors： Marsden BJ,Sauer FD,Blackwell BA,Kramer JK

更新日期：1989-03-31 00:00:00

abstract：:Endosomal trafficking of EGF receptor (EGFR) upon stimulation is a highly regulated process during receptor-mediated signaling. Recently, the sorting nexin (SNX) family has emerged as an important regulator in the membrane trafficking of EGFR. Here, we report the identification of a novel interaction between two membe...

journal_title：Biochemical and biophysical research communications

authors： Liu H,Liu ZQ,Chen CX,Magill S,Jiang Y,Liu YJ

更新日期：2006-04-07 00:00:00

abstract：:In humans, mutations in the gene encoding cereblon (CRBN) are associated with mental retardation. Although CRBN has been investigated in several cellular contexts, its function remains unclear. Here, we demonstrate that CRBN plays a role in regulating the ubiquitin-proteasome system (UPS). Heterologous expression of C...

journal_title：Biochemical and biophysical research communications

authors： Lee KM,Lee J,Park CS

更新日期：2012-10-26 00:00:00

abstract：:Stem cells have been identified using the DNA-binding dye Hoechst 33342 and flow cytometry (FCM) in various tissues known as the side population (SP). The present study shows, for the first time, the presence of side population cells in human deciduous dental pulp cells (DPCs). Flow cytometric identification revealed ...

journal_title：Biochemical and biophysical research communications

authors： Wang J,Wei X,Ling J,Huang Y,Huo Y,Zhou Y

更新日期：2010-09-24 00:00:00

abstract：:BA1544 from Bacillus anthracis was previously annotated as a transcription factor for the gene cluster ba1554 - ba1558, but has not been experimentally characterized. B. anthracis is an obligate pathogen causing fatal inhalational anthrax, and BA1544 is absolutely conserved in Bacillus species, including Bacillus cere...

journal_title：Biochemical and biophysical research communications

authors： Kim MI,Hong M

更新日期：2016-03-25 00:00:00

abstract：:The receptors for insulin and insulin-like growth factor (IGF)-I carry intrinsic tyrosine-specific protein kinases (TPK) in their cytoplasmic domains that show 84% homology. Our previous studies using tyrosine-containing synthetic polymers (Arch. Biochem. Biophys. 260, 416, 1988) revealed subtle differences between th...

journal_title：Biochemical and biophysical research communications

authors： Fujita-Yamaguchi Y,Kathuria S

更新日期：1988-12-30 00:00:00

abstract：:Cytosolic free calcium concentration ([Ca(2+)]i) is a central signalling element for the maintenance of endothelial barrier function. Under physiological conditions, it is controlled within narrow limits. Metabolic inhibition during ischemia/reperfusion, however, induces [Ca(2+)]i overload, which results in barrier fa...

journal_title：Biochemical and biophysical research communications

authors： Bosche B,Schäfer M,Graf R,Härtel FV,Schäfer U,Noll T

更新日期：2013-05-03 00:00:00

abstract：:Under many physiological circumstances, Na(+)- and Cl(-)-dependent, hemicholinium-3 (HC-3)-sensitive, high-affinity choline uptake (HACU) in cholinergic neurons is thought to be rate-limiting in the biosynthesis of acetylcholine (ACh). Based on sequence information provided by the Human Genome Project and the recently...

journal_title：Biochemical and biophysical research communications

authors： Apparsundaram S,Ferguson SM,George AL Jr,Blakely RD

更新日期：2000-10-05 00:00:00

abstract：:Spiroplasma eriocheiris, the cause of crab trembling disease, is a wall-less bacterium, related to Mycoplasmas, measuring 2.0-10.0 μm long. It features a helical cell shape and a unique swimming mechanism that does not use flagella; instead, it moves by switching the cell helicity at a kink traveling from the front to...

journal_title：Biochemical and biophysical research communications

authors： Terahara N,Tulum I,Miyata M

更新日期：2017-06-03 00:00:00

abstract：:Changes in proteasome activities were observed during starfish oocyte maturation induced by a maturation-inducing hormone, 1-methyladenine. Succinyl-Leu-Leu-Val-Tyr-MCA-hydrolyzing proteasome activity in immature oocytes showed a main peak of a 1500-kDa fraction and a shoulder centered at a 650-kDa fraction on Superos...

journal_title：Biochemical and biophysical research communications

authors： Sawada MT,Morinaga C,Izumi K,Sawada H

更新日期：1999-01-19 00:00:00

abstract：:The CCAAT/enhancer binding proteins (C/EBPs) and the peroxisome proliferator-activated receptors (PPARs) together regulate adipogenesis. The current work uses co-transfection studies to examine the C/ EBP dependence of PPAR gamma 2 transcription. Both C/ EBP alpha and C/EBP delta expression vectors activated transcrip...

journal_title：Biochemical and biophysical research communications

authors： Clarke SL,Robinson CE,Gimble JM

更新日期：1997-11-07 00:00:00

abstract：:We are interested in identifying proteins that interact with the MADS domain protein NMH7 of Medicago sativa. We use an affinity column with a synthetic peptide derived from the MADS domain of NMH7 which has been reported to mediate protein-protein interaction with non-MADS domain interacting proteins. We identified a...

journal_title：Biochemical and biophysical research communications

authors： Páez-Valencia J,Valencia-Mayoral P,Sánchez-Gómez C,Contreras-Ramos A,Hernández-Lucas I,Martínez-Barajas E,Gamboa-DeBuen A

更新日期：2008-11-28 00:00:00

abstract：:GLM, a luteolin derivative, shows anti-melanogenic effect via regulation of various signal molecules; however, it is unclear whether it also exerts anti-inflammatory effect. This study investigated the mechanisms of the anti-inflammatory effect of GLM on activated dendritic cells (DCs) to elucidate its therapeutic pot...

journal_title：Biochemical and biophysical research communications

authors： Kim WS,Song HY,Han JM,Byun EB

更新日期：2019-10-08 00:00:00

abstract：:In rice, Hd3a, GF14 and OsFD1 proteins, forming florigen activation complex, are key components in flowering time regulation. GF14 genes in rice response to biotic and abiotic stress has also been well addressed. The role of GF14e in rice defense has been well studied. However, whether Hd3a and OsFD1 play roles in def...

journal_title：Biochemical and biophysical research communications

authors： Ke Y,Wu M,Zhang Q,Li X,Xiao J,Wang S

更新日期：2019-06-11 00:00:00

abstract：:Expression of the MHC class I chain related molecules A and B (MICA/B) on tumor cell surface can signal the immune receptor NKG2D for tumor immune destruction. However, MIC was found to be shed by tumors in cancer patients, which negatively regulates host immunity and promotes tumor immune evasion and progression. The...

journal_title：Biochemical and biophysical research communications

authors： Wang X,Lundgren AD,Singh P,Goodlett DR,Plymate SR,Wu JD

更新日期：2009-09-25 00:00:00

abstract：:The transcription of human nm23 genes (nm23-H1, nm23-H2) is involved in suppression of tumor metastasis or tumor progression. Therefore the characterization of transcriptional regulatory mechanisms for both nm23 genes is very important. In this study we have isolated and analyzed the 5'-flanking region of the human nm...

journal_title：Biochemical and biophysical research communications

authors： Seifert M,Seib T,Engel M,Dooley S,Welter C

更新日期：1995-10-24 00:00:00

abstract：:Based on a previous finding that fusion of a somatic cell with an embryonic stem (ES) cell reprogrammed the somatic cell, genes for reprogramming transcription factors were selected and induced pluripotent stem (iPS) cell technology was developed. The cell fusion itself produced a tetraploid cell. To avoid nuclear fus...

journal_title：Biochemical and biophysical research communications

authors： Kim SM,Wada KI,Ueki M,Hosokawa K,Maeda M,Sakai Y,Ito Y

更新日期：2019-12-03 00:00:00

abstract：:alpha-Acaridial [2(E)-(4-methyl-3-pentenyl)butenedial] is a novel monoterpene secreted from the house dust mites. Because of its molecular nature of a highly reactive, small lipidic compound, we addressed whether alpha-acaridial might function as a haptenic allergen that induced allergic contact dermatitis. Mice sensi...

journal_title：Biochemical and biophysical research communications

authors： Sasai T,Hirano Y,Maeda S,Matsunaga I,Otsuka A,Morita D,Nishida R,Nakayama H,Kuwahara Y,Sugita M,Mori N

更新日期：2008-10-24 00:00:00

abstract：:Glycogen phosphorylase (a or b) binds 125I-calmodulin in a Ca2+-dependent manner, in the 125I-calmodulin overlay technique. This binding is quantitatively identical to 125I-calmodulin binding to myosin light chain kinase. In an in vitro assay, calmodulin stimulates phosphorylase activity at limiting concentrations of ...

journal_title：Biochemical and biophysical research communications

authors： Slaughter GR,Means AR

更新日期：1985-01-16 00:00:00

abstract：:Elevations in intracellular Ca(2+) ([Ca(2+)](i)) initiate insulin secretion from pancreatic beta-cells, but the secretory responses become rapidly desensitised to maintained elevations in [Ca(2+)](i). We have investigated the mechanisms underlying the Ca(2+) desensitization of insulin secretion using electrically perm...

journal_title：Biochemical and biophysical research communications

authors： Harris TE,Persaud SJ,Squires PE,Jones PM

更新日期：2000-04-21 00:00:00

abstract：:Alzheimer's disease (AD) is a progressive neurodegenerative disorder and the most common cause of dementia. Today, AD can be diagnosed with certainty only post-mortem, by histopathologic staining of Abeta plaques and neurofibrillary tangles in brain tissue sections. We have developed an ultra-sensitive assay potential...

journal_title：Biochemical and biophysical research communications

authors： Funke SA,Birkmann E,Henke F,Görtz P,Lange-Asschenfeldt C,Riesner D,Willbold D

更新日期：2007-12-28 00:00:00

abstract：:We recently demonstrated that metallothionein (MT)-1 A is a direct target gene negatively regulated by PU.1. In this study, we revealed that the expression of PU.1 was increased and accompanied by downregulation of MT-1A expression during TPA-induced THP-1 monocyte differentiation. Chromatin immunoprecipitation (ChIP)...

journal_title：Biochemical and biophysical research communications

authors： Suzuki S,Nakano H,Takahashi S

更新日期：2013-04-12 00:00:00

abstract：:Cepharanthine is a medicinal plant-derived natural compound which possesses potent anti-cancer properties. However, there is little report about its effects on lung cancer cells. In this study, we investigated the effects of cepharanthine on the cell viability and apoptosis in human non-small-cell lung cancer H1299 an...

journal_title：Biochemical and biophysical research communications

authors： Hua P,Sun M,Zhang G,Zhang Y,Tian X,Li X,Cui R,Zhang X

更新日期：2015-05-01 00:00:00