Abstract：
:Minor brain injury was inflicted with a small needle at 4 sites one week before the production of incomplete brain ischemia in the mouse. A bilateral carotid clamp was applied for 60 min under pentobarbital anesthesia, and the number of survivors at one week after the ischemic insult was compared with those in animals anesthetized only and those in a sham-operated group. The number of survivors in the brain-injured group was significantly higher than in the other two groups. The results suggest that anti-ischemic factors are released by the injured brain or that certain unknown protective mechanisms against ischemia become active following brain injury.
journal_name
Brain Resjournal_title
Brain researchauthors
Takahata Y,Shimoji Kdoi
10.1016/0006-8993(86)90091-0subject
Has Abstractpub_date
1986-09-03 00:00:00pages
368-71issue
2eissn
0006-8993issn
1872-6240pii
0006-8993(86)90091-0journal_volume
381pub_type
杂志文章相关文献
BRAIN RESEARCH文献大全abstract：:In addition to its stimulatory effect on prolactin release, the neuropeptide prolactin releasing peptide (PrRP) has been shown to be a mediator of the stress response. To analyze the neurochemical properties of the cells responsive to PrRP and involved in stress modulation, we examined PrRP receptor co-expression with...
journal_title：Brain research
pub_type： 杂志文章
doi：10.1016/s0006-8993(02)03183-9
更新日期：2002-10-11 00:00:00
abstract：:Stimuli such as noise or hypoxia can induce a release of ATP into the cochlear fluid spaces. At nanomolar concentrations, ATP affects neurotransmission and electrochemical regulation of sound transduction. At higher concentrations, ATP may exert cytotoxicity acting on specific P2X(7) receptor subunits, thus contributi...
journal_title：Brain research
pub_type： 杂志文章
doi：10.1016/j.brainres.2006.05.094
更新日期：2006-08-09 00:00:00
abstract：:The rostral brainstem and thalamus of awake cats were studied for depth correlates of a surface-recorded midlatency auditory evoked potential, wave "A', with a latency range of 17-25 ms. In response to clicks or pure tones, midlatency potentials were recorded from the level of the cuneiform nucleus (14-15 ms latencies...
journal_title：Brain research
pub_type： 杂志文章
doi：10.1016/0006-8993(83)91120-4
更新日期：1983-03-28 00:00:00
abstract：:Altered noradrenergic function is associated with alcoholism. Reduced brain norepinephrine (NE) concentrations and beta-adrenergic receptor supersensitivity following chronic alcohol consumption suggest a reduced level of noradrenergic neurotransmission. To further elucidate the reason for changes in noradrenergic fun...
journal_title：Brain research
pub_type： 杂志文章
doi：10.1016/0006-8993(94)90199-6
更新日期：1994-07-04 00:00:00
abstract：:Cerebellar Purkinje neurons possess AMPA ((RS)-alpha-amino-3-hydroxyl-5- methyl-4-isoxazolepropionic acid)-sensitive ionotropic glutamate receptors (AMPA GluRs) and ACPD ((1S,3R)-1-aminocyclopentane-1,3-dicarboxylic acid)-sensitive metabotropic glutamate receptors (mGluRs). The contributions of these receptors to resp...
journal_title：Brain research
pub_type： 杂志文章
doi：10.1016/0006-8993(93)91186-v
更新日期：1993-12-17 00:00:00
abstract：:Experimental studies and clinical observations show that spinal cord lesions are greatly enlarged by a process called secondary cell death. A detailed understanding of the molecular and cellular processes underlying these events is still lacking. In clinical studies using methylprednisolone in spinal cord injured pati...
journal_title：Brain research
pub_type： 杂志文章
doi：10.1016/0006-8993(94)01410-j
更新日期：1995-02-20 00:00:00
abstract：:Three to five microliters of 50% HRP in saline was injected along a central axis into one of the 6 extraocular muscles in each of 18 adult pigeons. The brain was fixed and serially sectioned 16-20 h postinjection and the HRP reacted with tetramethylbenzidine (TMB). HRP-labeled proprioceptive neurons were located in th...
journal_title：Brain research
pub_type： 杂志文章
doi：10.1016/0006-8993(82)90554-6
更新日期：1982-04-08 00:00:00
abstract：:Nitric oxide synthase (NOS) activity was examined in forebrain, cerebellum and optic lobes of adult domestic fowl, having a hereditary primary generalized convulsive disorder. NOS was approximately 2-fold higher in only the forebrain of adult epileptic fowl compared to non-epileptic (carrier) hatchmates. A significant...
journal_title：Brain research
pub_type： 杂志文章
doi：10.1016/0006-8993(96)00595-1
更新日期：1996-10-07 00:00:00
abstract：:The current study was performed to evaluate the mechanisms and therapeutic effects of overexpressing neuroglobin (Ngb) on spinal cord injury (SCI). Adeno-associated virus (AAV) was injected in the T12 section 7 days before SCI. Animals were randomly divided into four groups: a sham group, a vehicle group, an AAV-EGFP ...
journal_title：Brain research
pub_type： 杂志文章
doi：10.1016/j.brainres.2014.03.020
更新日期：2014-05-08 00:00:00
abstract：:Amino acid uptake by slices of brain is greatly diminished by incubation of the slices in glucose-free media. Uptake can be restored by the addition of a number of substrates, e.g., lactate, citrate, or oxaloacetate. The mixture of succinate, malate, and pyruvate (SMP, 20, 5, and mM) restored amino acid uptake better ...
journal_title：Brain research
pub_type： 杂志文章
doi：10.1016/0006-8993(77)90524-8
更新日期：1977-08-12 00:00:00
abstract：:Labyrinthine-intact guinea pigs received unilateral, brainstem cannula injections of (1) 2.5 micrograms of the selective dihydropyridine L-type Ca2+ channel agonist, Bay K 8644 (n = 4 animals); (2) 10 micrograms Bay K 8644 (n = 4); 12.5 micrograms of the selective dihydropyridine L-type Ca2+ channel antagonist, nifedi...
journal_title：Brain research
pub_type： 杂志文章
doi：10.1016/0006-8993(93)90677-f
更新日期：1993-12-10 00:00:00
abstract：:The addition of L-glutamic acid (Glu) alone, both Glu and glycine (Gly) or Glu/Gly/spermidine (SPD) was effective in potentiating [3H]5-methyl-10,11-dihydro-5H-dibenzo[a,d]cyclohepten-5,10- imine (MK-801) binding before equilibrium to an ion channel associated with the N-methyl-D-aspartate (NMDA) receptor complex in b...
journal_title：Brain research
pub_type： 杂志文章
doi：10.1016/0006-8993(94)91029-4
更新日期：1994-02-14 00:00:00
abstract：:Examination of the projection from area 2 of the sensory cortex to the motor cortex revealed substantial changes following lesion of the ventrolateral nucleus of the thalamus. These observed changes were as follows. (1) The polarity of the evoked potentials elicited by area 2 stimulation reversed in the depth of the m...
journal_title：Brain research
pub_type： 杂志文章
doi：10.1016/0006-8993(85)90838-8
更新日期：1985-10-14 00:00:00
abstract：:BW 1003C87, 5-(2,3,5-trichlorophenyl)-2,4-diaminopyrimidine ethane sulphonic acid, has been tested for its in vitro and in vivo effects on glutamate release in rat brain tissue, and for its cerebro-protective action in two rodent models of cerebral ischemia. In rat brain slices the release of glutamate evoked by verat...
journal_title：Brain research
pub_type： 杂志文章
doi：10.1016/0006-8993(92)91254-c
更新日期：1992-10-09 00:00:00
abstract：:Rats received 1-stage bilateral and sequential unilateral (serial) lesions of the posterior hypothalamus and were tested for the ability to regulate body temperature after a lengthy recovery period. The groups with lesion differed from the sham-operated groups in the cold, although not under ambient or warm conditions...
journal_title：Brain research
pub_type： 杂志文章
doi：10.1016/0006-8993(81)90309-7
更新日期：1981-08-31 00:00:00
abstract：:The ability to recognize previous experience depends on two neurocognitive processes, familiarity, fast-acting and relatively automatic, and recollection, slower-acting and more effortful. Familiarity appears to mature relatively early in development and is maintained with aging, whereas recollection shows protracted ...
journal_title：Brain research
pub_type： 杂志文章
doi：10.1016/j.brainres.2009.11.016
更新日期：2010-01-15 00:00:00
abstract：:During retinal development, common precursors give rise to various types of cells in a time course specific to each cell type. Previously, we demonstrated that the bHLH gene Hes1 inhibits neuronal differentiation whereas, in Hes1-null retina, precursors prematurely differentiate into neurons and form abnormal rosette-...
journal_title：Brain research
pub_type： 杂志文章
doi：10.1016/j.brainres.2004.01.045
更新日期：2004-04-09 00:00:00
abstract：:Mounting evidence suggests that sleep loss negatively affects learning and memory processes through disruption of hippocampal function. In the present study, we examined whether sleep loss alters the generation, differentiation, and survival of new cells in the dentate gyrus. Rats were sleep restricted by keeping them...
journal_title：Brain research
pub_type： 杂志文章
doi：10.1016/j.brainres.2005.10.020
更新日期：2005-12-14 00:00:00
abstract：:Our previous studies demonstrated that only a few days of housing in an enriched environment increases response strength and paired-pulse depression in the auditory cortex of awake and anesthetized rats [Engineer, N.D., Percaccio, C.R., Pandya, P.K., Moucha, R., Rathbun, D.L., Kilgard, M.P., 2004. Environmental enrich...
journal_title：Brain research
pub_type： 杂志文章
doi：10.1016/j.brainres.2007.07.062
更新日期：2007-10-12 00:00:00
abstract：:There is evidence that D1 and D2 dopamine receptor subtypes coexist at the cellular level in the striatum and act synergistically to mediate the effects of dopamine. Other data suggest that these receptor subtypes are largely segregated in different striatal projection pathways. We used in situ hybridization in serial...
journal_title：Brain research
pub_type： 杂志文章
doi：10.1016/0006-8993(93)90303-5
更新日期：1993-09-03 00:00:00
abstract：:The startle reflex is an unconditioned, quantifiable behavior used to study sensory modalities. We examined whether the acoustic startle reflex (ASR) was sensitive to lesions induced by focal cerebral ischemia. Sprague-Dawley rats were pre-screened for startle reflex responses 3-6 days prior to surgery and there were ...
journal_title：Brain research
pub_type： 杂志文章
doi：10.1016/j.brainres.2004.10.065
更新日期：2005-01-25 00:00:00
abstract：:Neurons immunoreactive for the calcium-binding protein calretinin (CR) were visualized in the substantia nigra (SN) pars compacta (SNc), reticulata (SNr) and lateralis (SNl), the ventral tegmental area (VTA) and the subthalamic nucleus (STN) of squirrel monkeys. The density of CR perikarya was high in VTA, moderate in...
journal_title：Brain research
pub_type： 杂志文章
doi：10.1016/0006-8993(95)01374-1
更新日期：1996-02-05 00:00:00
abstract：:The extraction and utilization of sound level changes in acoustic-autonomic reflex systems were studied on a vasoconstriction response in the tail of nonanesthetized rats. The vasoconstriction was found to depend on sound level and changes of level in the following ways. (a) It increased as a linear function of sound ...
journal_title：Brain research
pub_type： 杂志文章
doi：10.1016/0006-8993(80)90555-7
更新日期：1980-04-21 00:00:00
abstract：:Calretinin-immunoreactive structures in the anterior olfactory nucleus of the rat were studied using a polyclonal antibody, which does not cross-react with the highly homologous calcium-binding protein calbindin-D28k, and the avidin-biotin-peroxidase technique. Calretinin-immunopositive neurons were found in all regio...
journal_title：Brain research
pub_type： 杂志文章
doi：10.1016/s0006-8993(98)00023-7
更新日期：1998-04-06 00:00:00
abstract：:In normal adult cats we measured the density of staining for the activity of succinate dehydrogenase (SDH staining) in ventral horn cells of different sizes. The measurements were restricted to that part of the lumbar ventral horn (L6-L7) which is known to contain motoneurones of the peroneal nerve. A statistically si...
journal_title：Brain research
pub_type： 杂志文章
doi：10.1016/0006-8993(86)91542-8
更新日期：1986-10-15 00:00:00
abstract：:A study was undertaken of the role of the external lateral parabrachial subnucleus (PBNLe) in flavor preferences induced by the intragastric administration of predigested/cephalic food. These preferences were developed using two different learning procedures, concurrent and sequential. In the concurrent procedure, two...
journal_title：Brain research
pub_type： 杂志文章
doi：10.1016/s0006-8993(02)03032-9
更新日期：2002-09-20 00:00:00
abstract：:Males and females perform differently on a variety of training tasks. In the present study we examined performance of male and female rats while they were trained with a gross motor skill in which they learn to maintain their balance on an accelerating rotating rod (the accelerating rotarod). During training, many ani...
journal_title：Brain research
pub_type： 杂志文章
doi：10.1016/j.brainres.2014.11.045
更新日期：2015-09-24 00:00:00
abstract：:The concentration of soluble glial fibrillary acidic (GFA) protein and the specific activity of glutamine synthetase (GS) were estimated in 11 central nervous system (CNS) regions of the 90-day-old rat. Marked differences were observed in the regional distribution of these astrocyte marker proteins. The striatum and s...
journal_title：Brain research
pub_type： 杂志文章
doi：10.1016/0006-8993(85)90708-5
更新日期：1985-04-01 00:00:00
abstract：:Dendritic spines are actin-rich protrusions from the dendritic shaft, considered to be the locus where most synapses occur, as they receive the vast majority of excitatory connections in the central nervous system (CNS). Interestingly, hippocampal spines are plastic structures that contain a dense array of molecules i...
journal_title：Brain research
pub_type： 杂志文章,评审
doi：10.1016/j.brainres.2014.05.024
更新日期：2014-07-21 00:00:00
abstract：:An antagonist to amino acid evoked excitation, gamma-D-glutamylglycine (gamma-DGG) inhibits, dose-dependently, nociceptive C-fibre evoked field potentials and neuronal discharges in single nociceptive neurons in rat spinal cord. It is concluded that amino acids are possible transmitter substance(s) in nociceptive affe...
journal_title：Brain research
pub_type： 杂志文章
doi：10.1016/0006-8993(86)90798-5
更新日期：1986-08-06 00:00:00
