Abstract:
:Retinal prostheses attempt to restore some amount of vision to totally blind patients. Vision evoked this way will be however severely constrained because of several factors (e.g., size of the implanted device, number of stimulating contacts, etc.). We used simulations of artificial vision to study how such restrictions of the amount of visual information provided would affect performance on simple pointing and manipulation tasks. Five normal subjects participated in the study. Two tasks were used: pointing on random targets (LEDs task) and arranging wooden chips according to a given model (CHIPs task). Both tasks had to be completed while the amount of visual information was limited by reducing the resolution (number of pixels) and modifying the size of the effective field of view. All images were projected on a 10 degrees x 7 degrees viewing area, stabilised at a given position on the retina. In central vision, the time required to accomplish the tasks remained systematically slower than with normal vision. Accuracy was close to normal at high image resolutions and decreased at 500 pixels or below, depending on the field of view used. Subjects adapted quite rapidly (in less than 15 sessions) to performing both tasks in eccentric vision (15 degrees in the lower visual field), achieving after adaptation performances close to those observed in central vision. These results demonstrate that, if vision is restricted to a small visual area stabilised on the retina (as would be the case in a retinal prosthesis), the perception of several hundreds of retinotopically arranged phosphenes is still needed to restore accurate but slow performance on pointing and manipulation tasks. Considering that present prototypes afford less than 100 stimulation contacts and that our simulations represent the most favourable visual input conditions that the user might experience, further development is required to achieve optimal rehabilitation prospects.
journal_name
Vision Resjournal_title
Vision researchauthors
Pérez Fornos A,Sommerhalder J,Pittard A,Safran AB,Pelizzone Mdoi
10.1016/j.visres.2008.04.027subject
Has Abstractpub_date
2008-07-01 00:00:00pages
1705-18issue
16eissn
0042-6989issn
1878-5646pii
S0042-6989(08)00236-8journal_volume
48pub_type
杂志文章相关文献
VISION RESEARCH文献大全abstract::The widespread nature of diabetes affects all organ systems of an individual including the bone marrow. Long-term damage to the cellular and extracellular components of the bone marrow leads to a rapid decline in the bone marrow-hematopoietic stem/progenitor cells (HS/PCs) compartment. This review will highlight the i...
journal_title:Vision research
pub_type: 杂志文章,评审
doi:10.1016/j.visres.2017.06.016
更新日期:2017-10-01 00:00:00
abstract::A panel of anti-bovine rhodopsin monoclonal antibodies (MAbs) of defined site-specificity has been prepared and used for functional and topographic studies of rhodopsins. In order to select these antibodies, hybridoma supernatants that contained anti-rhodopsin antibodies have been screened by enzyme-linked immunosorbe...
journal_title:Vision research
pub_type: 杂志文章
doi:10.1016/0042-6989(91)90069-h
更新日期:1991-01-01 00:00:00
abstract::The presence of retinopetal fibers in mammals has been debated many times in the past two decades. Do rabbits have a retinopetal system? This question is addressed with the present investigations. In anesthetized and paralysed rabbits the b-wave and the oscillatory potentials (OP) are recorded at the cornea. The optic...
journal_title:Vision research
pub_type: 杂志文章
doi:10.1016/0042-6989(89)90110-7
更新日期:1989-01-01 00:00:00
abstract::The retinae of two species of teleosts, the rippled blenny Istiblennius edentulus and the blue tusk fish Choerodon albigena are examined in wholemount. The retinal topography of Nissl-stained cells within the ganglion cell layer in each species reveals a temporal (4.32 x 10(4) cells per mm2) and a nasal (3.83 x 10(4) ...
journal_title:Vision research
pub_type: 杂志文章
doi:10.1016/0042-6989(89)90089-8
更新日期:1989-01-01 00:00:00
abstract::Thirty patients with a reduced central vision due to diseases of the posterior pole were examined with the VERIS system developed by Sutter and Tran (Vis Res 1992;32:433-446) to characterize the topography of electroretinographic (ERG) changes in comparison to the results in 30 normal volunteers. Diagnoses included St...
journal_title:Vision research
pub_type: 杂志文章
doi:10.1016/s0042-6989(98)00071-6
更新日期:1998-12-01 00:00:00
abstract::Characterization of the visual system as a linear system has many consequences. One property implied by such a characterization is that signal-to-noise ratio at threshold is constant, so that the contrast energy of a sinusoidal grating at threshold depends on the effective noise passed by the filter used to detect the...
journal_title:Vision research
pub_type: 杂志文章
doi:10.1016/0042-6989(91)90209-n
更新日期:1991-01-01 00:00:00
abstract::Using the human WERI-Rb1 cell line as a model system, we performed a genome-wide search for retinal target genes of thyroid hormone (TH) via expression microarray analysis followed by quantitative real-time RT-PCR verification. We identified 12 novel retinal targets of TH, including 10 up-regulated genes (OPN1MW, OPN1...
journal_title:Vision research
pub_type: 杂志文章
doi:10.1016/j.visres.2007.04.023
更新日期:2007-08-01 00:00:00
abstract::Extra-retinal information about eye velocity is thought to play an important role in compensating the retinal motion experienced during an eye movement. Evidently this compensation process is prone to error, since stimulus properties such as contrast and spatial frequency have marked effect on perceived motion with re...
journal_title:Vision research
pub_type: 杂志文章
doi:10.1016/s0042-6989(03)00254-2
更新日期:2003-07-01 00:00:00
abstract::This paper reports an improved paradigm to measure visible persistence. The stimulus is a pair of lines stroboscopically displayed in successive positions moving in opposite directions. The subjects' judgement of simultaneous appearance of all the presented lines is used to estimate visible persistence. This paradigm ...
journal_title:Vision research
pub_type: 杂志文章
doi:10.1016/0042-6989(90)90058-s
更新日期:1990-01-01 00:00:00
abstract::A generally accepted notion in binocular vision is that we see the world as if viewed by a single eye, the cyclopean eye. A consequence of seeing the world from a single point in space is that the outlines of occluding and occluded surfaces have the same shape. We designed stereograms in which subjects aligned binocul...
journal_title:Vision research
pub_type: 杂志文章
doi:10.1016/0042-6989(95)00268-5
更新日期:1996-07-01 00:00:00
abstract:PURPOSE:Evidence exists for an additional inhibitory accommodative control system mediated by the sympathetic branch of the autonomic nervous system (ANS). This work aims to show the relative prevalence of sympathetic inhibition in young emmetropic and myopic adults, and to evaluate the effect of sympathetic facility o...
journal_title:Vision research
pub_type: 杂志文章
doi:10.1016/j.visres.2004.11.022
更新日期:2005-06-01 00:00:00
abstract::A computational model is proposed to account for the adaptive properties of the fly motion system. The response properties of motion-sensitive neurons in the fly are modelled using an underdamped adaptive scheme to adjust the time constants of delay filters in an array of Reichardt detectors. It is shown that the incr...
journal_title:Vision research
pub_type: 杂志文章
doi:10.1016/0042-6989(95)00301-0
更新日期:1996-08-01 00:00:00
abstract::Reading in peripheral vision is slow and requires large print, posing substantial difficulty for patients with central scotomata. The purpose of this study was to evaluate the effect of print size on reading speed at different eccentricities in normal peripheral vision. We hypothesized that reading speeds should remai...
journal_title:Vision research
pub_type: 杂志文章
doi:10.1016/s0042-6989(98)00072-8
更新日期:1998-10-01 00:00:00
abstract::We investigated the manner in which the outputs of the three postreceptoral mechanisms (red-green, blue-yellow and luminance) combine to determine contrast threshold. We used a subthreshold summation paradigm to test whether the combination of the postreceptoral mechanism outputs could be described by a probability su...
journal_title:Vision research
pub_type: 杂志文章
doi:10.1016/s0042-6989(98)00137-0
更新日期:1999-02-01 00:00:00
abstract::When a visual stimulus is displaced during a saccade the displacement is often not noticed unless it is large compared to the amplitude of the eye movement. Displacement detection is improved, however, if a blank intervenes between saccade target offset and the presentation of the displaced post-saccadic stimulus. Thi...
journal_title:Vision research
pub_type: 杂志文章
doi:10.1016/j.visres.2017.09.004
更新日期:2018-01-01 00:00:00
abstract::Bubbles is a classification image technique that randomly samples visual information from input stimuli to derive the diagnostic features that observers use in visual categorization tasks. To reach statistical significance, Bubbles performs an exhaustive and repetitive search in the stimulus space. To reduce the searc...
journal_title:Vision research
pub_type: 杂志文章
doi:10.1016/j.visres.2011.04.007
更新日期:2011-06-21 00:00:00
abstract::Small disparity stimuli applied to large random-dot patterns elicit machine-like vergence eye movements at short latency. We have examined the sensitivity of these eye movements to simulated orthogonal tropias in three normal subjects by recording (1) the effects of vertical disparities on the initial horizontal verge...
journal_title:Vision research
pub_type: 杂志文章
doi:10.1016/s0042-6989(02)00572-2
更新日期:2003-02-01 00:00:00
abstract::When a horizontal bar is presented after a single dot is shown at one of its ends, an illusory motion is seen which has been dubbed "motion induction" in the literature. The phenomenon has been attributed to a facilitation process which asymmetrically modulates the inputs to motion detectors, for instance by some sort...
journal_title:Vision research
pub_type: 杂志文章
doi:10.1016/s0042-6989(97)00004-7
更新日期:1997-07-01 00:00:00
abstract::Effects of optical correction on best-corrected grating acuity (vertical (V), horizontal (H), oblique (O)), vernier acuity (V, H, O), contrast sensitivity (1.5, 6.0, and 18.0 cy/deg spatial frequency, V and H), and stereoacuity were evaluated prospectively in 4- to 13-year-old astigmats and a non-astigmatic age-matche...
journal_title:Vision research
pub_type: 杂志文章
doi:10.1016/j.visres.2007.12.007
更新日期:2008-03-01 00:00:00
abstract::The present study examines the landing-site distributions of the eyes during natural reading of Japanese script: a script that mixes three different writing systems (Kanji, Hiragana, and Katakana) and that misses regular spacing between words. The results show a clear preference of the eyes to land at the beginning ra...
journal_title:Vision research
pub_type: 杂志文章
doi:10.1016/s0042-6989(01)00132-8
更新日期:2001-09-01 00:00:00
abstract::Image stability during self-motion is achieved via a combination of the optokinetic and vestibulo-ocular reflexes (OKR and VOR). To determine whether distinct neuronal mechanisms are used to calibrate eye movements driven by visual and vestibular signals, we examined the developmental maturation and adaptive plasticit...
journal_title:Vision research
pub_type: 杂志文章
doi:10.1016/j.visres.2004.09.006
更新日期:2004-12-01 00:00:00
abstract::To investigate the sources of spatial error in memory-guided saccades (MGS), we have trained monkeys on two different tasks: a MGS task and a delayed spatial match-to-sample (MTS) task. We first tested the effect of introducing a post-saccadic visual feedback on the accuracy of MGS. We found that visual feedback had a...
journal_title:Vision research
pub_type: 杂志文章
doi:10.1016/s0042-6989(02)00418-2
更新日期:2003-02-01 00:00:00
abstract::Edge integration refers to a hypothetical process by which the visual system combines information about the local contrast, or luminance ratios, at luminance borders within an image to compute a scale of relative reflectances for the regions between the borders. The results of three achromatic color matching experimen...
journal_title:Vision research
pub_type: 杂志文章
doi:10.1016/j.visres.2003.12.004
更新日期:2004-05-01 00:00:00
abstract::Patients with central vision loss are often advised by low vision rehabilitation professionals to read bolder print to ameliorate their reading difficulties. Is boldface print really effective in improving reading performance for people with central vision loss? In this study, we evaluated how reading speed depends on...
journal_title:Vision research
pub_type: 杂志文章
doi:10.1016/j.visres.2018.10.012
更新日期:2018-12-01 00:00:00
abstract::The present study showed that at equiluminance the critical duration of temporal integration became shorter as the chromatic saturation of an adaptation field was increased. These results suggest that the chromatic coding system (which is assumed to posses poorer temporal resolution or larger temporal integration time...
journal_title:Vision research
pub_type: 杂志文章
doi:10.1016/0042-6989(94)90005-1
更新日期:1994-04-01 00:00:00
abstract::This study investigated the influence of five days of moderate intensity aerobic exercise on the acquisition and consolidation of visual perceptual learning using a motion direction discrimination (MDD) task. The timing of exercise relative to learning was manipulated by administering exercise either before or after p...
journal_title:Vision research
pub_type: 杂志文章
doi:10.1016/j.visres.2017.08.007
更新日期:2018-11-01 00:00:00
abstract::We consider how local motion signals are combined to represent the movements of spatially extensive objects. A series of band-pass target dots, whose collective motion defined a moving contour, was positioned within a field of randomly moving noise dots. The visibility of the contours did not depend on the direction o...
journal_title:Vision research
pub_type: 杂志文章
doi:10.1016/s0042-6989(03)00329-8
更新日期:2003-09-01 00:00:00
abstract::(1) We studied the influence of photoperiod and unilateral lid suture on post-natal ocular growth in two types of White Leghorn chicks previously reported to respond differently to visual deprivation, Truslow and Cornell K chicks. We analyzed the chicks after 2 weeks of rearing, a time period commonly used in neuropha...
journal_title:Vision research
pub_type: 杂志文章
doi:10.1016/0042-6989(94)00232-b
更新日期:1995-05-01 00:00:00
abstract::Field spectral sensitivities of the pattern-elicited electroretinogram (PERG) were obtained from two subjects using a modified version of Stiles' two-color increment threshold procedure. A 540 nm checkerboard test pattern of 38 degrees dia was alternated at 8 Hz on a uniform adapting field of the same size. Test inten...
journal_title:Vision research
pub_type: 杂志文章
doi:10.1016/0042-6989(92)90064-p
更新日期:1992-11-01 00:00:00
abstract::The striate cortex of macaque monkeys contains an array of patches which stain heavily for the enzyme cytochrome oxidase (CO blobs). Cells inside and outside these blobs are often described as belonging to two distinct populations or streams. In order to better understand the function of the CO blobs, we measured the ...
journal_title:Vision research
pub_type: 杂志文章
doi:10.1016/0042-6989(94)00253-i
更新日期:1995-06-01 00:00:00