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Myocardial infarction in young Indian patients: risk factors and coronary arteriographic profile.

Abstract：

:One hundred four patients (101 men, three women), under 40 years of age, with myocardial infarction (MI), underwent coronary arteriography. Eighty patients had significant obstructive coronary artery disease (CAD) (group 1), 23 had normal coronary arteries (group 2), and one patient had coronary ostial stenosis as a result of nonspecific aortoarteritis (group 3). Coronary risk factors in group 1 included smoking (76.2%), hypercholesterolemia (36.3%), hypertension (32.5%), positive family history (28.7%), and diabetes mellitus (5%). Multiple risk factors were frequent (56.2%). Smoking was common (p less than 0.01) and diabetes mellitus less frequent (p less than 0.05) as compared to older (greater than 40 years) patients with MI and arteriographically proved CAD. The frequency of one-, two-, and three-vessel disease was 33.7%, 26.2%, and 40%, respectively, in group 1. Group 2 patients were almost devoid of coronary risk factors. The only group 3 patient had left coronary ostial stenosis with no risk factors. Similar to their counterparts in developed countries, young Indian patients with MI and obstructive CAD have a high frequency of coronary risk factors, especially smoking and severe multiple-vessel disease. Since normal coronary arteriograms are also frequent in this setting, a detailed evaluation is recommended for purposes of prognosis and management.

journal_name

Am Heart J

journal_title

American heart journal

authors

Kaul U,Dogra B,Manchanda SC,Wasir HS,Rajani M,Bhatia ML

doi

10.1016/0002-8703(86)90680-0

subject

Has Abstract

pub_date

1986-07-01 00:00:00

pages

71-5

issue

1

eissn

0002-8703

issn

1097-6744

pii

0002-8703(86)90680-0

journal_volume

112

pub_type

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