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Perisinusoidal cells in patients with normal liver histology. A morphometric study.

Abstract：

:We measured the number and the morphometric characteristics of perisinusoidal cells in perfusion-fixed biopsy samples from 7 control patients with normal liver histology. On 1-micron section, the number of cells was 18 +/- 1.5/0.1 mm2; 25% of cells did not apparently contain lipids. There were no significant zonal differences. The volume density of the cells represented 1 +/- 0.2% of the hepatic parenchyma. On ultrathin sections, the volume and surface densities of processes were 3.2 +/- 0.7% of sinusoid and 0.21 +/- 0.04 m2/cm3 of sinusoid respectively which represented 70% and 90% of total PSC volume and surface densities. Lipid volume density was 20.5 +/- 7.3% of the nucleated cell. More than 30% of cells contained less than 10% of lipids. There was no correlation between lipid volume density and RER surface density.

journal_name

J Hepatol

journal_title

Journal of hepatology

authors

Sztark F,Dubroca J,Latry P,Quinton A,Balabaud C,Bioulac-Sage P

doi

10.1016/s0168-8278(86)80047-2

subject

Has Abstract

pub_date

1986-01-01 00:00:00

pages

358-69

issue

3

eissn

0168-8278

issn

1600-0641

pii

S0168-8278(86)80047-2

journal_volume

2

pub_type

杂志文章

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