Abstract:
:Case-control studies involving more than two disease and referent categories may be analyzed by means of polychotomous logistic regression, an extension of the usual dichotomous logistic regression model. Although the standard method still may be used to compare the several disease subgroups in pairs, the polychotomous approach is advantageous in that it allows simultaneous estimation of the disease-specific parameters and direct hypothesis testing involving multiple disease categories. This is especially useful for assessing whether different disease types have different risk factors. The method is applied to a large case-control study of breast cancer involving three disease categories for which both categoric and continuous risk factors are considered. Substantive epidemiologic interpretation of polychotomous regression outputs is emphasized, as well as providing illustration of the practical aspects of the statistical method.
journal_name
Am J Epidemioljournal_title
American journal of epidemiologyauthors
Dubin N,Pasternack BSdoi
10.1093/oxfordjournals.aje.a114338subject
Has Abstractpub_date
1986-06-01 00:00:00pages
1101-17issue
6eissn
0002-9262issn
1476-6256journal_volume
123pub_type
杂志文章abstract::Active surveillance to detect all patients with Guillain-Barré syndrome who had had onset of illness from July 1, 1976 through April 30, 1977 was undertaken in Michigan after indications that the syndrome might be associated with the National Influenza Immunization Program of 1976-1977. Hospital record room librarians...
journal_title:American journal of epidemiology
pub_type: 杂志文章
doi:10.1093/oxfordjournals.aje.a113810
更新日期:1984-06-01 00:00:00
abstract::Accumulation of mitochondrial DNA (mtDNA) mutations leads to alterations of mitochondrial biogenesis and function that might produce a decrease in mtDNA content within cells. This implies that mtDNA content might be a potential biomarker associated with oxidative stress and inflammation. However, data on correlates of...
journal_title:American journal of epidemiology
pub_type: 杂志文章
doi:10.1093/aje/kwv175
更新日期:2016-01-15 00:00:00
abstract::Although it is generally believed that a simple lifestyle may promote health, a recent study among Trappist and Benedictine monks in the Netherlands reported an increase in general morbidity (Am J Epidemiol 1993;138:569-73). As this increased morbidity might be the consequence of an increased life expectancy, we studi...
journal_title:American journal of epidemiology
pub_type: 杂志文章
doi:10.1093/oxfordjournals.aje.a117500
更新日期:1995-04-15 00:00:00
abstract::Few studies have determined risk factors for diarrheal deaths in developing areas. The Ministry of Health of Lesotho, southern Africa, reported that 9.5% of children under five years of age who were hospitalized for diarrhea in 1984 died. Of 104 children under five years of age who died during hospitalization for diar...
journal_title:American journal of epidemiology
pub_type: 杂志文章
doi:10.1093/oxfordjournals.aje.a115085
更新日期:1988-12-01 00:00:00
abstract::A prevalence study was designed to evaluate host and seasonal risk factors associated with three systemic mycoses in dogs: blastomycosis, coccidioidomycosis, and histoplasmosis. Histoplasmosis was the most commonly diagnosed of the three diseases. All three of the mycoses occurred more frequently in male than female d...
journal_title:American journal of epidemiology
pub_type: 杂志文章
doi:10.1093/oxfordjournals.aje.a113077
更新日期:1981-02-01 00:00:00
abstract::A recent cohort mortality study of 19,608 male employees of a major Texas chemical production facility had suggested that they might be at higher risk of lung cancer compared with the male population of the United States or Texas but not with the male population of the five-county area in which they reside. An occupat...
journal_title:American journal of epidemiology
pub_type: 杂志文章
doi:10.1093/oxfordjournals.aje.a114370
更新日期:1986-07-01 00:00:00
abstract::The incidence and mortality of acute myocardial infarction (AMI) remain low in Japan despite major dietary changes and worsening cardiovascular risk factors, a situation that should have resulted in a substantial increase in AMI rates (Japanese paradox). The current trend in the incidence of AMI was examined for the p...
journal_title:American journal of epidemiology
pub_type: 杂志文章
doi:10.1093/aje/kwn064
更新日期:2008-06-01 00:00:00
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journal_title:American journal of epidemiology
pub_type: 杂志文章
doi:10.1093/oxfordjournals.aje.a115322
更新日期:1989-07-01 00:00:00
abstract::Hyperinsulinemia is associated with multiple metabolic disorders including high triglyceride level, low high density lipoprotein (HDL) cholesterol level, hypertension, and impaired glucose tolerance (IGT). This metabolic constellation is also called the insulin resistance syndrome. All previous data on clustering of t...
journal_title:American journal of epidemiology
pub_type: 杂志文章
doi:10.1093/oxfordjournals.aje.a009272
更新日期:1997-08-15 00:00:00
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journal_title:American journal of epidemiology
pub_type: 杂志文章
doi:10.1093/oxfordjournals.aje.a113644
更新日期:1983-09-01 00:00:00
abstract::The use of indirect standardization in the assessment of the fertility of occupationally exposed workers is briefly reviewed and critiqued. The calculation of expected births in the method of Levine et al. (J Occup Med 1980;22:781-91) is modified to eliminate negative bias. An example is given using data from a 1977 s...
journal_title:American journal of epidemiology
pub_type: 杂志文章
doi:10.1093/oxfordjournals.aje.a113707
更新日期:1983-12-01 00:00:00
abstract::The authors characterized human immunodeficiency virus (HIV) and hepatitis C virus (HCV) incidence and prospective changes in self-reported risk behavior over 2 years among 1,158 injection drug users (IDUs) recruited in Chennai, India, in 2005-2006. At baseline, HIV prevalence was 25.3%, and HCV prevalence was 54.5%. ...
journal_title:American journal of epidemiology
pub_type: 杂志文章
doi:10.1093/aje/kwq288
更新日期:2010-12-01 00:00:00
abstract::Differential survival associated with insulin-dependent diabetes mellitus (IDDM) was evaluated in a cross-country study using four population-based IDDM cohorts from Japan (n = 1,374), Israel (n = 610), Allegheny County, Pennsylvania (n = 995), and Finland (n = 5,144). For the purpose of this cross-country comparison,...
journal_title:American journal of epidemiology
pub_type: 杂志文章
doi:
更新日期:1995-09-15 00:00:00
abstract::The 1982-1984 Hispanic Health and Nutrition Examination Survey used ultrasonography to investigate risk factors for gallstone disease (gallstones or cholecystectomy). Mexican American, Cuban American, and Puerto Rican men (n = 968) and women (n = 1,325) aged 20-74 years were selected from household samples in nine sta...
journal_title:American journal of epidemiology
pub_type: 杂志文章
doi:10.1093/oxfordjournals.aje.a115574
更新日期:1990-05-01 00:00:00
abstract::Age at menarche, an early determinant of breast cancer risk, shows both a downward secular trend and marked differences by socioeconomic status, both presumably the reflection of dietary variations. A cohort study is being conducted in the Quebec City, Canada, area to assess the relation between diet, physical activit...
journal_title:American journal of epidemiology
pub_type: 杂志文章
doi:10.1093/oxfordjournals.aje.a115738
更新日期:1990-11-01 00:00:00
abstract::The authors evaluated the effect of air pollution on the occurrence of birth defects ascertained by the California Birth Defects Monitoring Program in neonates and fetuses delivered in southern California in 1987-1993. By using measurements from ambient monitoring stations of carbon monoxide (CO), nitrogen dioxide, oz...
journal_title:American journal of epidemiology
pub_type: 杂志文章
doi:10.1093/aje/155.1.17
更新日期:2002-01-01 00:00:00
abstract::The authors assessed the influence of age, period, and cohort effects on rates of preterm delivery in the United States. Rates of preterm delivery for singleton births (<37 weeks) in seven age groups (15-19, 20-24,., 45-49 years), five periods (1975, 1980, 1985, 1990, 1995), and 11 maternal birth cohorts (1926-1930, 1...
journal_title:American journal of epidemiology
pub_type: 杂志文章
doi:10.1093/aje/154.7.657
更新日期:2001-10-01 00:00:00
abstract::Whether risk compensation could offset the preventive effect of early initiation of antiretroviral therapy (ART) on human immunodeficiency virus (HIV) transmission remains unknown. Using virological and behavioral data collected 12 months after inclusion in the TEMPRANO randomized trial of early ART (Abidjan, Côte d'I...
journal_title:American journal of epidemiology
pub_type: 杂志文章
doi:10.1093/aje/kww127
更新日期:2016-11-15 00:00:00
abstract::The authors examined the association between the use of diethylstilbestrol during pregnancy and the risk of subsequent fatal breast cancer in a large prospective study of US adults. After 9 years of follow-up, 1,574 cases of fatal breast cancer were observed among 501,536 gravid women who reported no prior history of ...
journal_title:American journal of epidemiology
pub_type: 杂志文章
doi:10.1093/oxfordjournals.aje.a008976
更新日期:1996-10-01 00:00:00
abstract::During 1979, an outbreak of mixed enterovirus infections occurred in Kansas City and adjacent communities. Sixty-six enteroviruses and 7 adenoviruses were recovered from 73 persons in a survey hospital population. Twenty-eight persons yielded echovirus type 11, 22, echovirus type 6, and 16 either echovirus type 9 or C...
journal_title:American journal of epidemiology
pub_type: 杂志文章
doi:10.1093/oxfordjournals.aje.a113204
更新日期:1981-09-01 00:00:00
abstract::Cardiovascular morbidity has been associated with particulate matter (PM) air pollution, although the relation between pollutants and sudden death from cardiac arrest has not been established. This study examined associations between out-of-hospital cardiac arrests and fine PM (of aerodynamic diameter ≤2.5 μm, or PM(2...
journal_title:American journal of epidemiology
pub_type: 杂志文章
doi:10.1093/aje/kwq217
更新日期:2010-10-15 00:00:00
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journal_title:American journal of epidemiology
pub_type: 杂志文章
doi:10.1093/oxfordjournals.aje.a115404
更新日期:1989-11-01 00:00:00
abstract::The relation between self-reported physical activity and depressive symptoms was analyzed for 1,900 healthy subjects aged 25-77 years in the Epidemiologic Follow-up Study (1982-1984) to the first National Health and Nutrition Examination Survey (NHANES I). Depressive symptomatology as measured by the Center for Epidem...
journal_title:American journal of epidemiology
pub_type: 杂志文章
doi:10.1093/oxfordjournals.aje.a115087
更新日期:1988-12-01 00:00:00
abstract::While studies show that ultrafine and fine particles can be translocated from the lungs to the central nervous system, the possible neurodegenerative effect of air pollution remains largely unexplored. The authors examined the relation between black carbon, a marker for traffic particles, and cognition among 202 Bosto...
journal_title:American journal of epidemiology
pub_type: 杂志文章
doi:10.1093/aje/kwm308
更新日期:2008-02-01 00:00:00
abstract::To investigate whether greater intakes of calcium, vitamin D, or milk products may protect against ischemic heart disease mortality, the authors analyzed data from a prospective cohort study of 34,486 postmenopausal Iowa women 55-69 years old and without a history of ischemic heart disease who completed a dietary ques...
journal_title:American journal of epidemiology
pub_type: 杂志文章
doi:10.1093/oxfordjournals.aje.a009781
更新日期:1999-01-15 00:00:00
abstract::The occurrence of cancer of the corpus uteri in Denmark is examined by the use of data from the Danish Cancer Registry. The study population consists of 14,149 cases diagnosed with cancer of the corpus uteri between 1943 and 1980. Since 1943, the incidence has been steadily increasing. The trend in the incidence rates...
journal_title:American journal of epidemiology
pub_type: 杂志文章
doi:10.1093/oxfordjournals.aje.a113793
更新日期:1984-05-01 00:00:00
abstract::The relationship of cigarette-smoking and nonfatal myocardial infarction (AMI) was evaluated using the case-control approach. Overall, the association was present for smokers of one and two packs per day, the standardized rate-ratio estimates being 1.5 and 1.7, respectively. The association was strongest in those who ...
journal_title:American journal of epidemiology
pub_type: 杂志文章
doi:10.1093/oxfordjournals.aje.a112202
更新日期:1976-01-01 00:00:00
abstract::The authors studied the intake of vegetables, fruits, beta-carotene, and vitamins C and E in relation to the incidence of lung cancer. For 561 men from the town of Zutphen, the Netherlands, dietary history information was obtained in 1960, 1965, and 1970. During 1971-1990, 54 new cases of lung cancer were identified. ...
journal_title:American journal of epidemiology
pub_type: 杂志文章
doi:10.1093/oxfordjournals.aje.a009113
更新日期:1997-02-15 00:00:00
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journal_title:American journal of epidemiology
pub_type: 杂志文章
doi:10.1093/oxfordjournals.aje.a009303
更新日期:1997-09-15 00:00:00
abstract::This longitudinal study examined the mortality and cancer experience of workers at the Gulf Oil refinery located in Port Arthur, Texas. The cohort was studied over a period of 41 years, from 1937 to 1978, and consisted of 16,880 employees, with an accumulation of 406,198 person-years; 4361 deaths were observed. Emphas...
journal_title:American journal of epidemiology
pub_type: 杂志文章
doi:10.1093/oxfordjournals.aje.a113658
更新日期:1983-10-01 00:00:00