Abstract:
AIM:To clarify the factors affecting the success rate of endoscopic subureteral injection (ESI) treatment of vesicoureteral reflux (VUR). METHOD:All patients who had ESI treatment for VUR at our unit between 1999 and 2002 were retrospectively reviewed with regard to age, gender, causes of VUR, reflux grade, type of injected materials, number of injections, results of cystourethrograms (VCUG), and outcome. The injected implants were gluteraldehyde cross-linked bovine collagen (GclBC), dextranomers in sodium hyaluronan (DiSH) and calcium hydroxylapatite (CH). A successful result was defined as absence of VUR confirmed by VCUG performed 3 months after the ESI procedure. Basic descriptive statistics were performed along with the chi(2) test (p < 0.05 was significant). RESULTS:50 children (81 ureters) consisting of 27 girls (43 ureters) and 23 boys (38 ureters) with a mean age of 7.4 +/- 4.6 years constituted the study group. Grade III VUR was the most prominent grade (42%, 34 ureters) noted in all age groups. There was no significant difference between boys and girls with regard to the number of each grade of VUR. The success rate of first ESI procedure was 55.6% and was similar in each grade of VUR varying from 50 to 66%. Repeated injections have resulted in an overall success rate of 84%. No significant difference was noted between the age groups with regard to the success rate of ESI. Repeated ESI procedures were found to be unsuccessful in grade V VUR when compared to other grades (p < 0.05).There was a significant difference between primary reflux (76.5%, 62 ureters) and exstrophic (21%, 17 ureters) patients with regard to the grade of VUR and success rate of ESI. Exstrophic patients presented with a higher incidence of grade V VUR (41%) and with a lower success rate of ESI (64.7%). DiSH was the most commonly used agent (47 ureters) followed by CH (22 ureters) and GclBC (12 ureters). The success rates of the ESI procedure by each material were 91.5, 81.8, and 58.3%, respectively. No significant difference was noted between DiSH and CH. Low success rates by GclBCwere attributed to less usage of the material. 82% of the ESI procedures were done by surgeon A (49 ureters) and B (18 ureters) with a success rate of 96 and 72%, respectively. No significant difference was noted between A and B with regard to the success rate and type of injected material and the success rate in each grade of VUR (p > 0.05). No untoward effects were noted in short- and long-term follow-up (mean 4 +/- 1.2 years) of any patient. CONCLUSION:The ESI procedure provides a high success rate for the treatment of VUR which decreases in grade V VUR and presence of exstrophia vesica. Single injection of various materials has been found to be successful in most of the patients with grade II VUR, whereas grade IV and III patients have required repeated injections which have resulted in 100 and 94% success rates, respectively. Grade I VUR can be managed by close follow-up and appropriate antibiotic therapy without any surgical and/or endoscopic intervention. Patients presenting with grade V VUR should undergo open surgery if the first trial of ESI procedure results in failure as repeated injections have proved to be unsuccessful in this grade. The success rate of the ESI procedure does not seem to be affected by the type of injected material and different surgeons performing the procedure after achieving the learning curve.
journal_name
Urol Intjournal_title
Urologia internationalisauthors
Alkan M,Ciftci AO,Senocak ME,Tanyel FC,Buyukpamukcu Ndoi
10.1159/000137639subject
Has Abstractpub_date
2008-01-01 00:00:00pages
41-6issue
1eissn
0042-1138issn
1423-0399pii
000137639journal_volume
81pub_type
杂志文章abstract::Non-clear cell renal cell carcinoma accounts for about 20% of all kidney cancers. Tubulocystic carcinoma of the kidney (TCK) is a newly described entity with distinct molecular, genetic and clinical features. In 2013, it was one of five new renal tumors to be recognized by the International Society of Urological Patho...
journal_title:Urologia internationalis
pub_type: 杂志文章
doi:10.1159/000366287
更新日期:2015-01-01 00:00:00
abstract:OBJECTIVES:To introduce our modified retroperitoneoscopic living-donor nephrectomy (RPLDN) techniques and estimate the learning curve. METHODS:We retrospectively evaluated 121 consecutive donors who underwent modified RPLDN performed by a single surgeon. While the surgeon controlled the renal vessels, one hand was ins...
journal_title:Urologia internationalis
pub_type: 杂志文章
doi:10.1159/000493765
更新日期:2018-01-01 00:00:00
abstract::Lipoma of the adrenal gland is an extremely uncommon tumor detected incidentally at postmortem or during life when the patient undergoes investigations for other reasons. All tumors reported in the literature were very small in size. We report a case of lipoma of the adrenal gland in a 45-year-old male patient who was...
journal_title:Urologia internationalis
pub_type: 杂志文章
doi:10.1159/000030265
更新日期:1998-08-01 00:00:00
abstract:OBJECTIVES:To describe a case of cystic dysplasia of the testis (CDT), an uncommon cause of scrotal swelling in the pediatric patient. Clinic, therapy, fertility, and radiographic and pathologic findings are discussed and the 30 previously reported cases are reviewed. METHODS:A 9-year-old boy presented with asymptomat...
journal_title:Urologia internationalis
pub_type: 杂志文章,评审
doi:10.1159/000064351
更新日期:2002-01-01 00:00:00
abstract:OBJECTIVE:To report continence and urodynamic findings after radical cystectomy and urinary diversion with modified S-ileal neobladder between January 1993 and January 2013. PATIENTS AND METHODS:181 patients were enrolled. Continence status, reservoir sensation, compliance, capacity and activity were assessed. RESULT...
journal_title:Urologia internationalis
pub_type: 杂志文章
doi:10.1159/000356283
更新日期:2014-01-01 00:00:00
abstract::Twenty-five patients with transitional cell carcinoma of the bladder have been treated with combined therapy consisting of microwave regional coagulation and intracavitary irradiation. A remote-controlled after-loading system was utilized for the radiation therapy. The follow-up period ranged from 6 to 19 months with ...
journal_title:Urologia internationalis
pub_type: 杂志文章
doi:10.1159/000281330
更新日期:1988-01-01 00:00:00
abstract:BACKGROUND/AIMS:Periurethral cysts are a rare entity that may be confused with urethral diverticula. The protocol for diagnosis and management of these lesions is still unclear. We present our experience with six patients presenting with periurethral cysts. METHODS:From 2001 to 2005 we evaluated six patients with a pa...
journal_title:Urologia internationalis
pub_type: 杂志文章
doi:10.1159/000098068
更新日期:2007-01-01 00:00:00
abstract:BACKGROUND:Phytate as sodium salt has been used at high doses to treat stone-former patients with idiopathic hypercalciuria. The experimental and clinical hypocalciuric effects of dietary fiber have also been assigned to the presence of phytate as calcium-magnesium salt (phytin). As a consequence of the additional inte...
journal_title:Urologia internationalis
pub_type: 杂志文章
doi:10.1159/000077123
更新日期:2004-01-01 00:00:00
abstract::Calcium oxalate kidney stone formers are invariably advised to increase their fluid intake. In addition, magnesium therapy is often administered. Recently, a prospective study showed that a high dietary intake of calcium reduces the risk of symptomatic kidney stones. The present study was performed to test whether sim...
journal_title:Urologia internationalis
pub_type: 临床试验,杂志文章
doi:10.1159/000282958
更新日期:1997-01-01 00:00:00
abstract::A new device for the simultaneous in vivo measurement of pressure and developed force in the ureter is introduced. The 5-French catheter was cystoscopically inserted into the ureters of 12 dogs under anesthesia. The forms of the peristaltic waves for pressure and force show considerable differences. A basal force anal...
journal_title:Urologia internationalis
pub_type: 杂志文章
doi:10.1159/000282119
更新日期:1991-01-01 00:00:00
abstract::Aneurysmectomy and renal angioplasty were performed on a 14-year-old Japanese male and the blood pressure was within normal values 3 years after this surgery. Measurement of renal blood flow was facilitated by using 133Xe washout technique. This incidence is the eighth such case to be reported from Japan. ...
journal_title:Urologia internationalis
pub_type: 杂志文章
doi:10.1159/000280073
更新日期:1976-01-01 00:00:00
abstract::Vesicovaginal fistula (VVF) is a quite rare complication of gynecological surgery. The first attempt to repair the fistulous tract offers the best opportunity for cure. We report the successful repair of VVF in 2 patients using a combined anterior vaginal approach and porcine dermal collagen grafting as interposition ...
journal_title:Urologia internationalis
pub_type: 杂志文章
doi:10.1159/000176038
更新日期:2009-01-01 00:00:00
abstract:INTRODUCTION:Adherence to international guidelines is viewed as a prerequisite for optimal medical care delivery. Previously reported surveys for non-muscle-invasive bladder cancer (NMIBC) employed mailed questionnaires to urologists or patients resulting in conflicting degrees of agreement with existing guidelines. In...
journal_title:Urologia internationalis
pub_type: 杂志文章
doi:10.1159/000321926
更新日期:2011-01-01 00:00:00
abstract::Inflammatory myofibroblastic tumors are commonly seen in young adults and adolescents and commonly present with painless hematuria. We report a case of a 38-year-old woman who presented to us with urinary retention due to a prolapsing tumor mass from the urethra, which was discovered to be an inflammatory myofibroblas...
journal_title:Urologia internationalis
pub_type: 杂志文章
doi:10.1159/000350516
更新日期:2014-01-01 00:00:00
abstract:BACKGROUND:The last decade has seen the emergence of a variety of supine positions for carrying out percutaneous nephrolithotomy (PCNL). These positions all differ with regard to ease of puncture under image guidance, operative field availability, ability to make and dilate multiple tracts and ease of combining retrogr...
journal_title:Urologia internationalis
pub_type: 杂志文章
doi:10.1159/000341430
更新日期:2012-01-01 00:00:00
abstract::Twenty males underwent transrectal ultrasonography before and after ejaculation to examine possible alterations that could influence interpretation of seminal vesicle ultrasonography. The preejaculation length of 35 mm was significantly (p < 0.05) decreased to 30 mm after ejaculation. The mean width of the seminal ves...
journal_title:Urologia internationalis
pub_type: 杂志文章
doi:10.1159/000282404
更新日期:1992-01-01 00:00:00
abstract::We report a rare case of Budd-Chiari syndrome (BCS) as a postoperative complication after bilateral nephrectomy in a kidney transplant recipient with polycystic liver and kidneys. Contrast-enhanced computed tomography of the abdomen showed a narrowed inferior vena cava, compressed by the polycystic liver that moved do...
journal_title:Urologia internationalis
pub_type: 杂志文章
doi:10.1159/000504514
更新日期:2020-01-01 00:00:00
abstract::Adenosine triphosphate (ATP) and adenosine diphosphate (ADP) have been correlated with traditional semen parameters such as forward motility and sperm count. ATP and ADP were determined by a bioluminescence assay using the luciferin-luciferase reaction. Short boiling of the ejaculate was performed to inactivate phosph...
journal_title:Urologia internationalis
pub_type: 杂志文章
doi:10.1159/000282361
更新日期:1992-01-01 00:00:00
abstract:PURPOSE:To assess MRI/Transrectal Ultrasound (TRUS) fusion three-dimensional model-guided targeted biopsy (3D-Tb) versus TRUS-guided systematic biopsy (Sb) in detecting overall and high-Gleason-score (≥7) prostate cancer (PCa). METHODS:Pubmed and Web of science were searched. Studies with men having a suspicious lesio...
journal_title:Urologia internationalis
pub_type: 杂志文章,meta分析,评审
doi:10.1159/000484144
更新日期:2018-01-01 00:00:00
abstract:OBJECTIVES:To review the incidence of healthcare-associated infections/urinary tract infection (UTI), risk factors, microorganisms isolated and antibiotic resistances in patients who underwent lower urinary tract endoscopic surgery (LUTES) in a tertiary care hospital. METHODS:A prospective observational study was carr...
journal_title:Urologia internationalis
pub_type: 杂志文章
doi:10.1159/000488251
更新日期:2018-01-01 00:00:00
abstract:INTRODUCTION:β-HCG has been the only tumor marker evaluated in testicular vein (VT) blood until now. OBJECTIVE:To evaluate the correlation between the tumor markers β-HCG, AFP, PLAP, and LDH from the VT and peripheral blood as well as their significance in predicting tumor recurrence and tumor stage. METHODS:Patients...
journal_title:Urologia internationalis
pub_type: 杂志文章
doi:10.1159/000511649
更新日期:2020-12-17 00:00:00
abstract::Negotiating a tortuous or obstructed ureter with a wire can be time-consuming and sometimes tiring. The principle of using a slippery floppy wire and then replacing it with a stiff wire through a 5-french open-ended ureteral catheter yields a high success rate. The ureteral catheter can be used for a radiocontrast stu...
journal_title:Urologia internationalis
pub_type: 杂志文章
doi:10.1159/000282713
更新日期:1995-01-01 00:00:00
abstract:PURPOSE:To assess clinical outcomes and reimbursement costs of open and robotic-assisted radical prostatectomies in Germany. METHODS:Perioperative data of 499 open (2003-2006) and 932 (2008-2010) robotic-assisted radical prostatectomies as well as longitudinal reimbursement costs of an anonymized health insurance rese...
journal_title:Urologia internationalis
pub_type: 杂志文章
doi:10.1159/000431104
更新日期:2016-01-01 00:00:00
abstract::The pathophysiological considerations for regaining continence are discussed first. Our operation method for postprostatectomy incontinence is described and the results enumerated. The success rate is approximatively 80%. ...
journal_title:Urologia internationalis
pub_type: 杂志文章
doi:10.1159/000281155
更新日期:1986-01-01 00:00:00
abstract::The alpha-adrenergic innervation of the functional urethra is a well-known fact, while beta-adrenergic influence is rather unknown until now. We studied the influence of beta-stimulating and beta-blocking agents on the human urethra by the urethral pressure profile (UPP). A decrease of the UPP under orciprenaline sulf...
journal_title:Urologia internationalis
pub_type: 杂志文章
doi:10.1159/000280224
更新日期:1978-01-01 00:00:00
abstract:INTRODUCTION:The goal of the study was to define treatment rules for the uncommon, rarely (10%) malignant and chemorefractory Leydig cell tumors (LCT) of the testis. METHODS:The main clinical data of patients treated in centers affiliated to the GUONE (North-Eastern Uro-Oncological Group, Italy) were reviewed. We cons...
journal_title:Urologia internationalis
pub_type: 杂志文章,多中心研究
doi:10.1159/000200790
更新日期:2009-01-01 00:00:00
abstract::Presuming that complications associated with ureteral stenting vary in type and occurrence depending on the material and cross-section of the stent, six types of stents immersed in 48 different preparations of artificial urine for 1 month to observe surface changes with a scanning electron microscope. As a result, the...
journal_title:Urologia internationalis
pub_type: 杂志文章
doi:10.1159/000282206
更新日期:1991-01-01 00:00:00
abstract:OBJECTIVE:To assess the feasibility, problems and results of Nd-YAG laser core through urethrotomy in the management of failed urethroplasty for posttraumatic bulbomembranous urethral strictures. MATERIAL AND METHODS:61 patients with obliterative posttraumatic urethral strictures were treated by Nd-YAG laser core thro...
journal_title:Urologia internationalis
pub_type: 杂志文章
doi:10.1159/000058448
更新日期:2002-01-01 00:00:00
abstract::The prevalence of Chlamydia trachomatis and other microbes was studied in 94 semen samples from asymptomatic infertile males. Simultaneously, we sought evidence for inflammation of the genital tract by determining the polymorphonuclear granulocyte (PMN)-elastase concentration in the seminal plasma. The C. trachomatis ...
journal_title:Urologia internationalis
pub_type: 杂志文章
doi:10.1159/000282675
更新日期:1994-01-01 00:00:00
abstract:OBJECTIVE:In spite of readily available evidence-based guidelines on urolithiasis treatment, practical applications of treatments vary from country to country, or even within countries. The choice of treatment depends not only on the evidence, but often on general non-medical decision factors such as infrastructure, ex...
journal_title:Urologia internationalis
pub_type: 杂志文章
doi:10.1159/000441041
更新日期:2016-01-01 00:00:00