Short-term memory, exploration and locomotor activity in aged rats.

Abstract:

:Behavioral profiles of young (3-6 months) and aged (24-27 months) rats were compared in three respects: (1) short-term memory, (2) exploration and (3) locomotor activity. Compared to young rats, aged rats were impaired in the 8-arm radial maze acquisition, but not in the delayed reinforced alternation acquisition. They had lower scores of spontaneous alternation, of exploration of a novel object and of a novel environment. Their exploratory activity was lower in a simple environment but similar in a complex environment. Their spontaneous locomotor activity was lower during the dark part of the cycle (8 p.m.-8 a.m.) but not different during the light part of the cycle (8 a.m.-8 p.m.). These results suggest that with respect to short-term memory and exploration, differences between aged and young rats may be influenced by a "complexity" factor and may be secondary to differences in motivation and reactions to novelty.

journal_name

Neurobiol Aging

journal_title

Neurobiology of aging

authors

Willig F,Palacios A,Monmaur P,M'Harzi M,Laurent J,Delacour J

doi

10.1016/0197-4580(87)90033-9

subject

Has Abstract

pub_date

1987-09-01 00:00:00

pages

393-402

issue

5

eissn

0197-4580

issn

1558-1497

pii

0197-4580(87)90033-9

journal_volume

8

pub_type

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