Naltrexone in treatment of self injurious behavior: a clinical study.

Abstract:

:It has been suggested that the parenteral opiate antagonist, naloxone, might ameliorate self-injurious behavior. However, clinical studies have had conflicting results. We have evaluated whether a potent oral opiate antagonist, naltrexone, is effective in the treatment of this condition. The study was conducted on two young, profoundly mentally retarded adults, who exhibited intractable self-injurious behavior. A double-blind, placebo-controlled, within-subject-withdrawal design was utilized. One subject was studied for 12 weeks and the other one for 18 weeks. No measurable effects on the self-injurious behavior were observed.

journal_name

Res Dev Disabil

authors

Szymanski L,Kedesdy J,Sulkes S,Cutler A,Stevens-Our P

doi

10.1016/0891-4222(87)90002-3

subject

Has Abstract

pub_date

1987-01-01 00:00:00

pages

179-90

issue

2

eissn

0891-4222

issn

1873-3379

journal_volume

8

pub_type

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