Optical properties of human melanocytic nevi in vivo.

abstract：:The temperature dependence of the uptake phase of 5-aminolevulinic acid (ALA) and the following production phase of protoporphyrin IX (PpIX) in normal mouse skin was investigated. A cream containing 20% ALA was topically applied on the skin for 10 min. The amount of ALA-induced PpIX was evaluated by measuring the fluo...

journal_title：Photochemistry and photobiology

authors： Juzenas P,Sørensen R,Iani V,Moan J

更新日期：1999-04-01 00:00:00

abstract：:There is a need to improve the selectivity of photodynamic therapy and for better targeting of tumor cells within specific tumor compartments. Selective in vitro phototoxicity of a human bladder carcinoma cell line 647V has been achieved by targeting sulfonated aluminum phthalocyanines (AlSPc) with monoclonal antibodi...

journal_title：Photochemistry and photobiology

authors： Morgan J,Lottman H,Abbou CC,Chopin DK

更新日期：1994-11-01 00:00:00

abstract：:Skh:HR-1 hairless mice were irradiated chronically with sub-erythemal doses of UVB radiation, and a number of biochemical parameters in the skin were determined after 6, 12, 18, and 24 wk of exposure. The parameters measured were water, collagen, elastin, and glycosaminoglycan content; collagenase and elastase levels;...

journal_title：Photochemistry and photobiology

authors： Chatterjee R,Benzinger MJ,Ritter JL,Bissett DL

更新日期：1990-01-01 00:00:00

abstract：:All-trans retinoic acid (ATRA) plays essential roles in the normal biological processes and the treatment of cancer and skin diseases. Considering its photosensitive property, many studies have been focused on the photochemistry of ATRA. In this study, we investigated the transient phenomena in the laser flash photoly...

journal_title：Photochemistry and photobiology

authors： Li K,Wang M,Wang T,Sun D,Zhu R,Sun X,Wu X,Wang SL

更新日期：2013-09-01 00:00:00

abstract：:In cultured human keratinocytes, the tumor suppressor p53 acts as a control element in the protective response to UVB radiation and is affected by a variety of factors linked to cellular adhesion and differentiation. Because keratinocytes within the epidermis are not a homogeneous population but differ in their prolif...

journal_title：Photochemistry and photobiology

authors： Will K,Neben M,Schmidt-Rose T,Deppert W,Wittern KP,Bergemann J

更新日期：2000-03-01 00:00:00

abstract：:In the present work, we study the photodynamic action of cercosporin (cerco), a naturally occurring photosensitizer, on human cancer multicellular spheroids. U87 spheroids exhibit double the uptake of cerco than T47D and T98G spheroids as shown by flow cytometry on the single cell level. Moreover, cerco is efficiently...

journal_title：Photochemistry and photobiology

authors： Grigalavicius M,Mastrangelopoulou M,Arous D,Juzeniene A,Ménard M,Skarpen E,Berg K,Theodossiou TA

更新日期：2020-05-01 00:00:00

abstract：:Drug delivery systems (DDS) capable of releasing an active molecule at the appropriate site and at a rate that adjusts in response to the progression of the disease or to certain functions/biorhythms of the organism are particularly appealing. Biocompatible materials sensitive to certain physiological variables or ext...

journal_title：Photochemistry and photobiology

authors： Alvarez-Lorenzo C,Bromberg L,Concheiro A

更新日期：2009-07-01 00:00:00

abstract：:Dark-grown leaves of maize (Zea mays), wheat (Triticum aestivum), wild-type pea (Pisum sativum) and its light-independent photomorphogenesis mutant (lip1) have different proportions of protochlorophyllide (Pchlide) forms as revealed by low-temperature fluorescence emission spectra. Four discrete spectral forms of Pchl...

journal_title：Photochemistry and photobiology

authors： Myśliwa-Kurdziel B,Amirjani MR,Strzałka K,Sundqvist C

更新日期：2003-08-01 00:00:00

abstract：:As our understanding of the role of UV in causing skin cancer continues to expand, researchers and clinicians must continue to remain up to date on the various means by which UV exposure can be quantified. The purpose of this article was to review the current methods used to measure lifetime exposure to UV and to summ...

journal_title：Photochemistry and photobiology

authors： Worswick SD,Cockburn M,Peng D

更新日期：2008-11-01 00:00:00

abstract：:Excessive sun exposure can cause sunburn, suntan, skin photoaging, and even skin cancer. Skin photoaging conflicts with the human pursuit of a young and beautiful appearance. Some research data indicate that the incidence of skin cancer in the Chinese has been increasing, although it remains lower than in whites. To e...

journal_title：Photochemistry and photobiology

authors： Wan M,Hu R,Li Y,Wang Y,Xie X,Yue P,Guan L,Lai W

更新日期：2016-09-01 00:00:00

abstract：:Exposure to ultraviolet radiation results in increased levels of intradermal cis-urocanic acid (cUCA) and alters cutaneous immunity by interfering with processing and presentation of antigen by Langerhans cells. Reports on effects of systemic immunotoxicity with 30 day cUCA exposure in laboratory rodents include thymi...

journal_title：Photochemistry and photobiology

authors： Prater MR,Gogal RM Jr,De Fabo EC,Longstreth J,Holladay SD

更新日期：2003-04-01 00:00:00

abstract：:The in vitro cell survival, localization and ultrastructural changes following irradiation were examined in 9L glioma cells sensitized with a new photosensitizer, lysyl chlorin p6 (LCP). In clonogenic assays, LCP was 10-100-fold more phototoxic than photofrin II on a microgram/mL basis. Lysyl chlorin p6 uptake was blo...

journal_title：Photochemistry and photobiology

authors： Leach MW,Higgins RJ,Autry SA,Boggan JE,Lee SJ,Smith KM

更新日期：1993-11-01 00:00:00

abstract：:The photoinduced covalent binding of the title compound to native and heat denatured DNA is described. The level of binding has been measured by UV (for DNA) and atomic absorption (for Rh) analysis. Quantum efficiencies of 6.4 x 10(-4) mol Rh per mol photons and 1.6 x 10(-3) mol Rh per mol photons have been determined...

journal_title：Photochemistry and photobiology

authors： Mahnken RE,Bina M,Deibel RM,Luebke K,Morrison H

更新日期：1989-04-01 00:00:00

abstract：:To determine the origin of the UV-specific CC to TT tandem mutation at the CC site, we made a duplex DNA decamer containing a uracil cis-syn cyclobutane dimer (CBD) as the deaminated model of a cytosine dimer. Two-dimensional 1H-NMR spectroscopy studies were performed on this sequence where two adenines (Ade) were opp...

journal_title：Photochemistry and photobiology

authors： Lee HM,Kim JK

更新日期：2002-10-01 00:00:00

abstract：:There are controversial reports in the literature concerning the reactivity of singlet oxygen ((1)O(2)) with the redox probe 2',7'-dichlorodihydrofluorescein (DCFH). By carefully preparing solutions in which (1)O(2) is quantitatively generated in the presence of DCFH, we were able to show that the formation rate of th...

journal_title：Photochemistry and photobiology

authors： Daghastanli NA,Itri R,Baptista MS

更新日期：2008-09-01 00:00:00

abstract：:In this paper, we propose a new physical method in combination with mixed solution of thiazone and polyethylene glycol 400 (thiazone PEG 400 solution) penetration into tissue to assess the skin optical clearing. Four treatments were performed: (1) control group (C); (2) polyethylene glycol 400 (PEG400); (3) 0.25% thia...

journal_title：Photochemistry and photobiology

authors： Zhong H,Guo Z,Wei H,Guo L,Wang C,He Y,Xiong H,Liu S

更新日期：2010-05-01 00:00:00

abstract：:Near-UV (337 nm) photoactivation of the 5-hydroxytryptophan decarboxylation reaction producing serotonin has been observed. The photoactivation effect was investigated as a function of fluence rate and fluence, and pH. Photoactivation of decarboxylase activity was found to occur at nearly neutral pH values (low activi...

journal_title：Photochemistry and photobiology

authors： Fraikin GY,Strakhovskaya MG,Ivanova EV,Rubin AB

更新日期：1989-04-01 00:00:00

abstract：:The infrared spectrum of monomeric unsubstituted coumarin (C9H6O2; 2H-1-benzopyran-2-one), isolated in solid argon at 10 K is presented and assigned. The UV-induced (lambda>200 nm) unimolecular photochemistry of the matrix-isolated compound was studied experimentally. Three main photoreactions were observed: (a) decar...

journal_title：Photochemistry and photobiology

authors： Kuş N,Breda S,Reva I,Tasal E,Ogretir C,Fausto R

更新日期：2007-09-01 00:00:00

abstract：:Neutral filter elution at pH 7.2 and 9.6 was used to measure the induction of DNA lesions in human P3 teratocarcinoma cells by monochromatic 254-, 270-, 313-, 334-, 365-, and 405-nm radiation and by 60 gamma rays. In this assay DNA double-strand breaks (dsb) increase the rate of elution of DNA from cell lysates on a f...

journal_title：Photochemistry and photobiology

authors： Peak JG,Peak MJ

更新日期：1990-08-01 00:00:00

abstract：:Photochemo and photodynamic therapies are minimally invasive approaches for the treatment of cancers and powerful weapons for competing bacterial resistance to antibiotics. Synthetic and naturally occurring quinazolinones are considered privileged anticancer and antibacterial agents, with several of them to have emerg...

journal_title：Photochemistry and photobiology

authors： Panagopoulos A,Balalas T,Mitrakas A,Vrazas V,Katsani KR,Koumbis AE,Koukourakis MI,Litinas KE,Fylaktakidou KC

更新日期：2021-01-01 00:00:00

abstract：:Exploration of environmental dynamics using intrinsic biological probe tryptophan is very important; however, it suffers from various difficulties. An alternative probe, kynurenine (KN), has been found to be an efficient probe for the ultrafast dynamics in the biological environment (Goswami et al., [2010] J. Phys. Ch...

journal_title：Photochemistry and photobiology

authors： Rakshit S,Goswami N,Pal SK

更新日期：2012-01-01 00:00:00

abstract：:Activation of expression of the heme oxygenase (HO) gene appears to be involved in a cellular defense system in mammalian cells. We now demonstrate that while HO-1 mRNA levels are strongly inducible in dermal fibroblasts they are barely inducible in human epidermal keratinocytes following oxidative stress (UVA radiati...

journal_title：Photochemistry and photobiology

authors： Applegate LA,Noël A,Vile G,Frenk E,Tyrrell RM

更新日期：1995-03-01 00:00:00

abstract：:Blue visible light damage to retinal pigment epithelial cells occurs through a photooxidative mechanism and the resultant damage is hypothesized to induce or exacerbate age-related macular degeneration. The purpose of the present study was to identify changes in the cell growth and the expression of hepatocyte growth ...

journal_title：Photochemistry and photobiology

authors： Chu R,Zheng X,Chen D,Hu DN

更新日期：2006-09-01 00:00:00

abstract：:A spectral resolution procedure was used to resolve the absorption, excitation and emission spectra of the fluorescein monoanion in a number of solvent-water mixtures. This permitted an analysis of the effect of the solvent environment on the spectral properties of the monoanion and on the lactone/monoanion/dianion tr...

journal_title：Photochemistry and photobiology

authors： Klonis N,Sawyer WH

更新日期：2000-08-01 00:00:00

abstract：:We compared mutagenesis and sister chromatid exchange (SCE) induction by 193 nm and 308 nm pulsed excimer laser radiation with 254 nm low intensity continuous wave UV light in Chinese hamster ovary (CHO) cells in culture. The 254 nm radiation was most mutagenic of the radiations, in accordance with expectation, and al...

journal_title：Photochemistry and photobiology

authors： Rasmussen RE,Hammer-Wilson M,Berns MW

更新日期：1989-04-01 00:00:00

abstract：:In the vertebrate retina, rods mediate twilight vision and cones mediate daylight vision. Their photoresponse characteristics are different. The light-sensitivity of a cone is 10(2)-10(3) times lower than that of a rod. In addition, the photoresponse time course is much faster in cones. The mechanism characterizing co...

journal_title：Photochemistry and photobiology

authors： Tachibanaki S,Shimauchi-Matsukawa Y,Arinobu D,Kawamura S

更新日期：2007-01-01 00:00:00

abstract：:Tetracycline molecules offer several sites for peroxidative metabolism of the type known to lead to oxygen consumption and electronic excitation. Accordingly, when tetracycline and chlortetracycline were exposed to horseradish peroxidase in the presence of hydrogen peroxide, oxygen was taken up and light emission was ...

journal_title：Photochemistry and photobiology

authors： Gilio VE,Cilento G

更新日期：1993-09-01 00:00:00

abstract：:Photoisomerization of a protein-bound chromophore is the basis of light sensing and signaling in many photoreceptors. Phytochrome photoreceptors can be photoconverted reversibly between the Pr and Pfr states through photoisomerization of the methine bridge between rings C and D. Ground-state heterogeneity of the chrom...

journal_title：Photochemistry and photobiology

authors： Stensitzki T,Yang Y,Wölke AL,Knapp EW,Hughes J,Mroginski MA,Heyne K

更新日期：2017-05-01 00:00:00

abstract：:The thermodynamic parameters for the formation of the free radicals upon electron transfer quenching of the flavin triplet state (3FMN) by tryptophan and tyrosine, Delta(FR)H and Delta(FR)V, were obtained in aqueous solution by the application of laser-induced optoacoustic spectroscopy at various temperatures. The Del...

journal_title：Photochemistry and photobiology

authors： Crovetto L,Martínez-Junza V,Braslavsky SE

更新日期：2006-01-01 00:00:00

abstract：:Albino hairless mice (Skh: HR-1) exposed chronically to sub-erythemal doses of UV radiation display physical, visible and histological alterations. Using narrow bandwidth radiation covering the UV radiation spectrum from 280-380 nm, the wavelength dependence of these alterations was determined. The wavelength dependen...

journal_title：Photochemistry and photobiology

authors： Bissett DL,Hannon DP,Orr TV

更新日期：1989-12-01 00:00:00