Abstract：
:Atherosclerosis is the most frequent cause of ischemic heart disease and cerebrovascular disorders. The condition is the leading cause of death in Western societies. At the core of this condition is the atherosclerotic plaque. It is within the structure of this lesion that multiple biochemical and cellular processes interact influencing its vulnerability to rupture and as a result acute ischemic events. This article will discuss the pathophysiology behind the atherosclerotic plaque, particularly those elements that lead to its instability and the medical tools currently available to counteract it.
journal_name
P R Health Sci Jjournal_title
Puerto Rico health sciences journalauthors
Mundo-Sagardía JA,Figueroa Y,Altieri PI,Banchs HL,Escobales N,Crespo MJsubject
Has Abstractpub_date
2008-09-01 00:00:00pages
241-6issue
3eissn
0738-0658issn
2373-6011journal_volume
27pub_type
杂志文章abstract：OBJECTIVE:Due to advances in the care of people living with HIV/AIDS (PLWHA), life expectancy significantly increased, putting this group vulnerable to age-related comorbidities, such as cancer. The objective of this study was to describe the knowledge of cancer screening (cervical, breast, anal, colon, prostate) and o...
journal_title：Puerto Rico health sciences journal
pub_type： 杂志文章
doi：
更新日期：2016-09-01 00:00:00
abstract：:113 rhesus monkeys, representing 4 age classes, 3 matrilines, and immigrant adult males in a 161-member Cayo Santiago-derived troop living in a 2-acre enclosure, were sampled for levels of plasma ACTH and cortisol during a period of capture and brief cage confinement for routine veterinary examination. ACTH levels sho...
journal_title：Puerto Rico health sciences journal
pub_type： 杂志文章
doi：
更新日期：1989-04-01 00:00:00
abstract：OBJECTIVE:Left ventricular (LV) function parameters have major diagnostic and prognostic importance in heart disease. Measurement of ventricular function with tomographic (SPECT) radionuclide ventriculography (MUGA) decreases camera time, improves contrast resolution, accuracy of interpretation and the overall reliabil...
journal_title：Puerto Rico health sciences journal
pub_type： 杂志文章
doi：
更新日期：2015-09-01 00:00:00
abstract：OBJECTIVE:To evaluate the utility of the substituted judgement standard in terminally ill patients by determining agreement between patients, family proxies and physicians. BACKGROUND:Several studies have addressed the utility of substituted judgement, showing conflicting data whether surrogates are accurate predictin...
journal_title：Puerto Rico health sciences journal
pub_type： 杂志文章
doi：
更新日期：1999-12-01 00:00:00
abstract：:Surveillance for emerging diseases is critically dependent on four factors: reporting methods, case definition, laboratory diagnosis, and knowledge of the disease among health-care professionals. The dengue hemorrhagic fever (DHF) surveillance system in Puerto Rico collects patient data from three sources: dengue case...
journal_title：Puerto Rico health sciences journal
pub_type： 杂志文章
doi：
更新日期：1999-12-01 00:00:00
abstract：OBJECTIVE:To determine the prevalence of hypothyroidism in an adult female population in Puerto Rico and to determine the relationship between hypothyroidism, bone mineral density and vertebral and non-vertebral fractures in this population. METHODS:Data from the 400 subjects' database of the Latin American Vertebral ...
journal_title：Puerto Rico health sciences journal
pub_type： 杂志文章
doi：
更新日期：2013-06-01 00:00:00
abstract：:This is the case of an 11-year-old girl who presented with a right adnexal mass and vague abdominal symptoms since seven months prior to her hospital admission for surgery. CT-scan and sonographic images were those of a benign lesion, probably ovarian torsion or infarction. Serum tumoral markers were normal. A right s...
journal_title：Puerto Rico health sciences journal
pub_type： 杂志文章
doi：
更新日期：2003-09-01 00:00:00
abstract：:We tested a dietary supplement formulated with a synergistic combination of vitamins, minerals, herbals in a group of 15 patients with uncontrolled diabetes type II. The supplement was given for 30 days. Fasting blood glucose was measured prior to the supplementation and at the end of the 30 days treatment period. Blo...
journal_title：Puerto Rico health sciences journal
pub_type： 杂志文章
doi：
更新日期：2004-06-01 00:00:00
abstract：:As part of the January, 1988 trapping of the Cayo Santiago rhesus colony a number of morphometric measurements and serum were collected to examine metabolic and hormonal changes associated with spontaneous obesity. Measurements included body weights, crown-rump lengths, abdominal and scapular skinfolds and circumferen...
journal_title：Puerto Rico health sciences journal
pub_type： 杂志文章
doi：
更新日期：1989-04-01 00:00:00
abstract：OBJECTIVE:To compare the effectiveness of intravenous immunoglobulin (IVIG) alone, high dose methylprednisolone (HDMP) alone and the combination of IVIG and HDMP in the treatment of childhood immune thrombocytopenic purpura (ITP). BACKGROUND:Acute ITP in children is a self-limited disease with a benign course and low ...
journal_title：Puerto Rico health sciences journal
pub_type： 杂志文章
doi：
更新日期：2000-03-01 00:00:00
abstract：:Folate deficiency is one of today's most common vitamin deficiencies in women. Women who consume a low level of folate during pregnancy are at risk for poor pregnancy outcomes including neural tube defects (NTD). However, other factors such as heredity, social class, maternal age, birth order, maternal diet, length of...
journal_title：Puerto Rico health sciences journal
pub_type： 杂志文章,评审
doi：
更新日期：1997-12-01 00:00:00
abstract：:Human physiology depends on countless biochemical reactions, numerous of which are co-dependent and interrelated. The speed and level of completion of reactions usually depend on the availability of precursors and enzymes. The enzymatic activity depends on the bioavailability of micronutrient cofactors such as vitamin...
journal_title：Puerto Rico health sciences journal
pub_type： 杂志文章
doi：
更新日期：2015-03-01 00:00:00
abstract：:Atrial fibrillation (AF) is the most common sustained arrhythmia in adults. It is a significant public health problem in the United States where it affects 2.2 million Americans and almost 10% of the population older than 80 years. It should be emphasized that the prevalence of AF increases with advancing age and with...
journal_title：Puerto Rico health sciences journal
pub_type： 杂志文章,评审
doi：
更新日期：2004-12-01 00:00:00
abstract：:The therapy of chronic myeloid leukemia (CML), characterized by the presence of the Philadelphia chromosome in the clonal hematopoietic stem cells, has changed dramatically in the last year with the development of a specific inhibitor of the BCR-ABL tyrosine kinase. This medication, STI571 or imatinib, was recently ap...
journal_title：Puerto Rico health sciences journal
pub_type： 杂志文章,评审
doi：
更新日期：2002-09-01 00:00:00
abstract：:Exposure to lead in children living on a former landfill in Vega Baja-Puerto Rico, a United States Environmental Protection Agency (USEPA) designated Superfund Site, is a major health concern. Direct contact with lead-contaminated soil is considered a major exposure source. However, there is a lack of information rega...
journal_title：Puerto Rico health sciences journal
pub_type： 杂志文章
doi：
更新日期：2003-06-01 00:00:00
abstract：:Patterns of stress-responsiveness were studied in 19 adolescent male rhesus monkeys (Macaca mulatta) who are part of the free-ranging colony on Cayo Santiago, PR. Morphometric and blood samples were obtained as each male was captured and after holding overnight. Subject heart rate was recorded on Day 2, using surface ...
journal_title：Puerto Rico health sciences journal
pub_type： 杂志文章
doi：
更新日期：1989-04-01 00:00:00
abstract：:Diabetes mellitus (DM) is a chronic disorder of metabolism, which is commonly found in the Puerto Rican population. In this article the current concepts in diagnosis, classification and correct coding of DM are discussed. Since the cutoff point for diagnosing DM was lowered to 126 mg/dl in a fasting plasma glucose lev...
journal_title：Puerto Rico health sciences journal
pub_type： 杂志文章
doi：
更新日期：2001-06-01 00:00:00
abstract：:Rat gene 33 (g33) mRNA has a widespread tissue distribution. Insulin and various agents such as glucocorticoids, phorbol esters and plant lectins regulate G33 expression in rat hepatoma cells. The regulation of g33 by insulin and a phorbol ester was examined in two Chinese Hamster ovary (CHO) cell lines, CHO-T cells (...
journal_title：Puerto Rico health sciences journal
pub_type： 杂志文章
doi：
更新日期：1999-09-01 00:00:00
abstract：OBJECTIVE:Fungal spores are ubiquitous in the atmosphere worldwide, but their distribution is not homogeneous at different locations. Most studies have compared airborne fungal spores ecology in temperate zones, but less is known about the tropics. METHODS:This study compared, through statistical analysis of archived ...
journal_title：Puerto Rico health sciences journal
pub_type： 杂志文章
doi：
更新日期：2020-09-01 00:00:00
abstract：:We have studied the spontaneous interaction with small, inedible objects by group-living Saimiri. Twenty-one animals living in a large outdoor enclosure were presented with a set of 10 novel objects of diverse materials, colors, sizes, and shapes. We have used a sampling technique to record the number of monkeys inter...
journal_title：Puerto Rico health sciences journal
pub_type： 杂志文章
doi：
更新日期：1985-12-01 00:00:00
abstract：:Thymidine kinase is a key enzyme responsible for the activation of several anticancer and antiviral drugs. As the first enzyme in the salvage pathway of thymidine, it is regulated by the feedback inhibition exerted by the end-product of the pathway, namely thymidine 5'-triphosphate. 5'-Aminothymidine is a non-toxic an...
journal_title：Puerto Rico health sciences journal
pub_type： 杂志文章,评审
doi：
更新日期：1994-03-01 00:00:00
abstract：:Cayo Santiago has provided the opportunity to study primate biology in a free-ranging neutral environment free of provocative human influences. Rarely, if ever, does such a situation occur in natural rhesus habitats in Asia. This Cayo Santiago advantage has permitted fine-scale analyses of the details of behavior, eco...
journal_title：Puerto Rico health sciences journal
pub_type： 历史文章,杂志文章
doi：
更新日期：1989-04-01 00:00:00
abstract：OBJECTIVES:The recent boom in patient education on chronic hepatitis C has resulted in a worldwide increase in the diagnosis of this condition. Available treatment is expensive and associated with significant side effects; therefore, many patients seek for alternative medicine. Silybum marianum is a natural herb known ...
journal_title：Puerto Rico health sciences journal
pub_type： 杂志文章,随机对照试验
doi：
更新日期：2004-06-01 00:00:00
abstract：:The physical parameters of nuclear size and granularity, and the biological parameters of nuclear protein and DNA content were simultaneously measured by the flow cytometric analysis of mitogen-activated Rhesus monkey lymphocytes. These experiments were performed with the purpose of establishing baseline values for mi...
journal_title：Puerto Rico health sciences journal
pub_type： 杂志文章
doi：
更新日期：1991-08-01 00:00:00
abstract：:Small island exigencies and a legacy of colonial jurisprudence set the stage for this three-year study in 2001-2003 of abortion practice on several islands of the northeast Caribbean: St. Martin, St. Maarten, Anguilla, Antigua and St Kitts. Based on in-depth interviews with 26 physicians, 16 of whom were performing ab...
journal_title：Puerto Rico health sciences journal
pub_type： 杂志文章
doi：
更新日期：2008-03-01 00:00:00
abstract：:Endothelial cell proliferation and differentiation into blood capillaries (i.e., angiogenesis) are essential for growth and development, wound healing, osetogenesis, etc. But abnormal angiogenesis during tumor progression could lead to serious consequences. Angiogenesis is a complex biochemical process, and is often d...
journal_title：Puerto Rico health sciences journal
pub_type： 杂志文章
doi：
更新日期：1998-12-01 00:00:00
abstract：:The identification of Streptococcus mutans from dental plaque samples with rapid systems, such as the RapID STR System, has not been recommended by the manufacturers. In this study, we evaluated the use of the above method for the identification of 34 human dental plaque Streptococcus mutans strains which had been ide...
journal_title：Puerto Rico health sciences journal
pub_type： 杂志文章
doi：
更新日期：1993-12-01 00:00:00
abstract：:Seventy two partial subperiosteal implants were inserted in 52 patients. Thirty six of these implants had a classical design in which the submerged structure had thick primary and secondary connectors. Thirty six implants had a newly designed submerged structure consisting of long and thin primary connectors with groo...
journal_title：Puerto Rico health sciences journal
pub_type： 临床试验,杂志文章
doi：
更新日期：1994-09-01 00:00:00
abstract：BACKGROUND:The etiology of Inflammatory Bowel Diseases, Crohn's disease (CD) and ulcerative colitis (UC), is unknown. These diseases have a higher incidence in industrialized countries and their pathogenesis involves an over-reaction of the immune system. A genetic factor is believed to predispose to the development of...
journal_title：Puerto Rico health sciences journal
pub_type： 杂志文章
doi：
更新日期：2001-09-01 00:00:00
abstract：:DNA microarray is a technology that simultaneously evaluates quantitative measurements for the expression of thousands of genes. DNA microarrays have been used to assess gene expression between groups of cells of different organs or different populations. In order to understand the role and function of the genes, one ...
journal_title：Puerto Rico health sciences journal
pub_type： 杂志文章,评审
doi：
更新日期：2009-06-01 00:00:00
