Abstract：
:Bypass grafting around a neuroma-in-continuity entails coapting a nerve graft above and below the injured segment using two sequential end-to-side repairs. The proximal repair is analogous to what has been classically described as an end-to-side repair; the axons from the intact nerve sprout into the end of a recipient nerve and travel distally. At the distal connection, however, axons in the graft must enter the side of the intact nerve and find their way to appropriate end organs. This process has not been well investigated. To examine this, a reverse end-to-side repair, suturing the distal end of the peroneal nerve to the side of a transected and repaired tibial nerve, was performed in 20 rats. A primary end-to-end repair of the tibial nerve was performed in 10 additional rats. Twelve weeks later, contraction forces of the gastrocnemius muscle were measured following proximal stimulation. Measurements were repeated following elimination of potential axonal pathways to identify which axons (peroneal or tibial) had achieved greater reinnervation. The results indicated that both groups of axons had achieved significant reinnervation. This study supports the idea that a reverse end-to-side repair can result in axonal invasion of an intact but regenerating nerve and achieve functional recovery.
journal_name
J Reconstr Microsurgjournal_title
Journal of reconstructive microsurgeryauthors
Isaacs JE,Cheatham S,Gagnon EB,Razavi A,McDowell CLdoi
10.1055/s-0028-1088230subject
Has Abstractpub_date
2008-10-01 00:00:00pages
489-96issue
7eissn
0743-684Xissn
1098-8947journal_volume
24pub_type
杂志文章abstract：:Twenty patients with methicillin-resistant Staphylococcus aureus (MRSA) osteomyelitis and bone infection were treated with vascularized fibular grafts. There were 16 males and four females, and the patient ages at operation ranged from 17 to 73 years. Nine of the lesions affected the femur, eight the tibia, and there ...
journal_title：Journal of reconstructive microsurgery
pub_type： 杂志文章
doi：10.1055/s-2004-818044
更新日期：2004-01-01 00:00:00
abstract：:The enhancement of blood flow in experimental skin flaps following postischemic perfusion washout was investigated in rats. Unilateral island skin flaps based on the superficial epigastric vessels were raised and subjected to 6 hr of primary ischemia. Group 1 was designated as a control and did not undergo postischemi...
journal_title：Journal of reconstructive microsurgery
pub_type： 杂志文章
doi：10.1055/s-2007-1006753
更新日期：1993-11-01 00:00:00
abstract：:The use of a free compound rib-latissimus dorsi osteomusculocutaneous flap is described, for reconstruction of the tibia and soft tissue of the leg. The entire flap depends on the thoracodorsal artery for its blood supply. Dye injection studies of the artery demonstrated continuity between it and the intercostal arter...
journal_title：Journal of reconstructive microsurgery
pub_type： 杂志文章
doi：10.1055/s-2007-1007032
更新日期：1986-10-01 00:00:00
abstract：:Perforator flaps based on either musculocutaneous or septocutaneous perforators are no longer a curiosity, but rather in the past decade have become "workhorse" soft tissue alternatives. Yet a keener understanding of their anatomy abetted by sophisticated imaging techniques has revealed other deep fascia perforators w...
journal_title：Journal of reconstructive microsurgery
pub_type： 杂志文章,评审
doi：10.1055/s-0032-1315777
更新日期：2012-10-01 00:00:00
abstract：:This study aimed to produce prefabricated nerve graft as effective as autologous nerve graft without donor site morbidity for repairing segmental nerve defects. Thirty rats were used and were separated into three groups. In the first group, vein graft excised from jugular vein was sutured to make a bridge between epin...
journal_title：Journal of reconstructive microsurgery
pub_type： 杂志文章
doi：10.1055/s-2008-1076087
更新日期：2008-02-01 00:00:00
abstract：:In a three-year-11-month-old girl, an excess big toe was transferred microsurgically to replace a congenital floating thumb. The reconstructed thumb was evaluated nine years after the transfer. It showed almost normal growth, compared with the contralateral side, and the aesthetic result was excellent. However, the pa...
journal_title：Journal of reconstructive microsurgery
pub_type： 杂志文章
doi：10.1055/s-2007-1006565
更新日期：1994-01-01 00:00:00
abstract：BACKGROUND:The authors presented their clinical experience and demonstrated surgical methods for reconstructing complex bone and soft tissue defects of the hand by using modified chimeric radial collateral artery perforator flaps. METHODS:Surgical procedures that employed 16 modified chimeric radial collateral artery ...
journal_title：Journal of reconstructive microsurgery
pub_type： 杂志文章
doi：10.1055/s-0034-1390324
更新日期：2015-03-01 00:00:00
abstract：BACKGROUND: Investigating correlations between clinical, instrumental, and genetic features of primary lymphedema (PL) with the aim to facilitate the diagnosis, the staging, and the management of this subgroup of patients. METHODS: A prospective observational study was conducted from September 2016 to May 2018, includ...
journal_title：Journal of reconstructive microsurgery
pub_type： 杂志文章
doi：10.1055/s-0039-1698748
更新日期：2020-03-01 00:00:00
abstract：:Twenty-eight vascularized toe-joint transfers performed on 25 patients were reviewed. A number of different techniques were used: proximal interphalangeal joint or metacarpophalangeal joint reconstruction, one-stage double joint transfer, and interphalangeal thumb or trapezometacarpal joint replacement. Using these ty...
journal_title：Journal of reconstructive microsurgery
pub_type： 杂志文章
doi：10.1055/s-2007-1006819
更新日期：1990-07-01 00:00:00
abstract：:A practical use of personal digital cameras for taking digital photographs in the microsurgical field through an operating microscope is described. This inexpensive and practical method for acquiring microscopic images at the desired magnification combines the advantages of the digital camera and the operating microsc...
journal_title：Journal of reconstructive microsurgery
pub_type： 杂志文章
doi：10.1055/s-2003-42500
更新日期：2003-07-01 00:00:00
abstract：:The feasibility of composite tissue allografts (CTAs) has been demonstrated by the successful transplantation of the hand, abdomen, and face. However, the survival of these transplants depends on immunosuppression. Our laboratory is interested in achieving tolerance to decrease the risks associated with the use of chr...
journal_title：Journal of reconstructive microsurgery
pub_type： 杂志文章
doi：10.1055/s-0030-1247717
更新日期：2010-04-01 00:00:00
abstract：BACKGROUND: The volume of the profunda femoris artery perforator (PAP) flap limits its indications to small- and medium-sized breast reconstructions after modified radical mastectomy for cancer. We report a modified PAP flap design, including not only a vertical extension that increases its volume but also the skin sur...
journal_title：Journal of reconstructive microsurgery
pub_type： 杂志文章
doi：10.1055/s-0038-1649508
更新日期：2019-01-01 00:00:00
abstract：BACKGROUND:The purpose of this study is to identify whether intraoperative use of vasoactive medications increases the risk of free flap failure or complications through a systematic review and meta-analysis. MATERIALS AND METHODS:PubMed/MEDLINE, EMBASE, and Scopus databases were searched for studies published through...
journal_title：Journal of reconstructive microsurgery
pub_type： 杂志文章,meta分析,评审
doi：10.1055/s-0035-1563381
更新日期：2016-02-01 00:00:00
abstract：BACKGROUND:We present the clinical application of the sixth internal mammary artery perforator (IMAP) and superior epigastric artery perforator (SEAP) flaps for the treatment of defects resulting from the excision of large lower sternal and upper abdominal keloids. Perforator selection and flap design were based solely...
journal_title：Journal of reconstructive microsurgery
pub_type： 杂志文章
doi：10.1055/s-0035-1556078
更新日期：2015-11-01 00:00:00
abstract：:To evaluate the root neurotization properties of extraplexal donor nerves, an avulsion injury model of brachial plexus was created and repaired by C 3,4 nerve-root transfers in the rabbit. Eighteen rabbits were divided into three groups. In Group 1 (n = 6), the right C 5,6 nerve roots were avulsed and bridged by a ner...
journal_title：Journal of reconstructive microsurgery
pub_type： 杂志文章
doi：10.1055/s-2003-40583
更新日期：2003-05-01 00:00:00
abstract：:The authors present two cases in which the venous drainage of transferred flaps was compromised and the flaps were salvaged by vein grafts. Traditionally, once transferred free flaps had become congestive, surgeons would re-anastomose the thrombosed veins, and administer anticoagulants or carry out peripheral vessel d...
journal_title：Journal of reconstructive microsurgery
pub_type： 杂志文章
doi：10.1055/s-2004-815639
更新日期：2003-11-01 00:00:00
abstract：BACKGROUND:Locally advanced breast cancer (LABC) and chest wall osteoradionecrosis (ORN) often require extensive and composite tissue resection, including muscles, ribs, pleura, and lung parenchyma. As such, these cases necessitate complex reconstructive procedures for skeletal chest wall reconstruction and soft tissue...
journal_title：Journal of reconstructive microsurgery
pub_type： 杂志文章
doi：10.1055/s-0035-1563395
更新日期：2016-02-01 00:00:00
abstract：BACKGROUND: The distally based sural flap (DBSF) is one of the armamentarium in the lower limb reconstruction. However, the flap has not gained popularity due to concerns about its reliability and donor site morbidity. Based on the anatomy characterization, we combined and developed five modifications to improve the va...
journal_title：Journal of reconstructive microsurgery
pub_type： 杂志文章
doi：10.1055/s-0040-1716744
更新日期：2020-09-17 00:00:00
abstract：:There is increased clinical use of computer-assisted design (CAD) and computer-assisted modeling (CAM) for osseous flap reconstruction, particularly in the head and neck region. Limited information exists about methods to optimize the application of this new technology and for cases in which it may be advantageous ove...
journal_title：Journal of reconstructive microsurgery
pub_type： 杂志文章
doi：10.1055/s-0033-1358789
更新日期：2014-06-01 00:00:00
abstract：:The authors treated 14 patients (13 men and one woman), using a sensate radial forearm flap. Their ages at operation ranged from 27 to 67 years (mean: 52 years). Preoperative conditions were amputations in 10 cases, degloving injury in three, and crush injury in one. Reconstructive sites involved the thumb in nine cas...
journal_title：Journal of reconstructive microsurgery
pub_type： 杂志文章
doi：10.1055/s-2000-9375
更新日期：2000-11-01 00:00:00
abstract：:The authors' experiences with 34 free lower TRAM flap transfers, in which 19 primary reconstructions and 15 secondary reconstructions were successfully achieved, are reviewed. The free TRAM flap yielded better results than the pedicled TRAM flap in cases where reconstruction of the infraclavicular and anterior axillar...
journal_title：Journal of reconstructive microsurgery
pub_type： 杂志文章
doi：10.1055/s-2007-1006676
更新日期：1992-01-01 00:00:00
abstract：:An expanded latissimus dorsi flap (expanded LD flap) was transferred in two patients with severe post-burn neck contracture. Free flaps created using standard techniques are of limited size and sometimes cannot cover the defect after excision of scar tissue, particularly when a severe burn scar extends to the facial r...
journal_title：Journal of reconstructive microsurgery
pub_type： 杂志文章
doi：10.1055/s-2002-33018
更新日期：2002-07-01 00:00:00
abstract：:A retrospective evaluation of the functional results after reconstructive treatment with levator scapulae transfer and scapulo-spinal fasciodesis by fascia lata slings for complete chronic trapezius palsy is presented. Five patients (ages 6 to 40 years) were operated on between 1988 and 1991 because of incapacitating ...
journal_title：Journal of reconstructive microsurgery
pub_type： 杂志文章
doi：10.1055/s-2007-1006544
更新日期：1995-07-01 00:00:00
abstract：:The effects of piracetam on flap survival, ischemia-reperfusion (I/R) injury, and vascular endothelial growth factor (VEGF) expression were evaluated in this study. Unipedicled epigastric flap model was used in 36 rats and was evaluated within 4 groups. The flap was elevated and untreated in Group 1. Postoperative pir...
journal_title：Journal of reconstructive microsurgery
pub_type： 杂志文章
doi：10.1055/s-0031-1281523
更新日期：2011-09-01 00:00:00
abstract：:The goal of craniofacial reconstruction is not only life-saving but also facial aesthetics. From this viewpoint the authors evaluated the facial symmetry of patients after craniofacial reconstruction. The subjects were seven patients reconstructed after craniofacial resections. Their CT or MR images were evaluated jus...
journal_title：Journal of reconstructive microsurgery
pub_type： 杂志文章
doi：10.1055/s-2006-951313
更新日期：2006-10-01 00:00:00
abstract：:Achilles-tendon repair wounds are prone to breakdowns and secondary infections, compromising the integrity of the repair and the ultimate function of the repaired tendon. Unlike defects resulting from tumor excision, burns, or trauma, Achilles-tendon repair wounds have their own special considerations. The dissection ...
journal_title：Journal of reconstructive microsurgery
pub_type： 杂志文章
doi：10.1055/s-2000-8389
更新日期：2000-10-01 00:00:00
abstract：:Twenty patients with intractable diseases in the upper extremity were treated using free vascularized fibula grafts. There were 13 men and seven women. Three patients had traumatic bone defects, five had post-traumatic nonunions, two had congenital pseudoarthroses, seven had defects after tumor resection, and three ha...
journal_title：Journal of reconstructive microsurgery
pub_type： 杂志文章
doi：10.1055/s-2007-1000131
更新日期：1999-10-01 00:00:00
abstract：:Systematic scanning electron microscopic observations of the healing mechanism in the endothelium of rat carotid arteries were carried out at the site of anastomosis. The site of needle holes and stitches are the main locations for thrombocyte adhesion and aggregation in normal vascular anastomosis. The repair process...
journal_title：Journal of reconstructive microsurgery
pub_type： 杂志文章
doi：
更新日期：1989-10-01 00:00:00
abstract：BACKGROUND: Subfascial anterolateral thigh (ALT) flap thickness can be problematic with regards to bulk, oral competence, shoe-fit, or as a potential source of recurrent wound breakdown. We have utilized distinct upper thigh fascial planes to fashion thin (suprafascial) or super-thin (periscarpal) ALT flaps to improve ...
journal_title：Journal of reconstructive microsurgery
pub_type： 杂志文章
doi：10.1055/s-0037-1607426
更新日期：2018-03-01 00:00:00
abstract：:The use of nerve conduits has evolved from a previous experimental idea to a clinical reality over the last ten years. An overview of the literature on the clinical use of nerve conduits in peripheral-nerve repair is presented. ...
journal_title：Journal of reconstructive microsurgery
pub_type： 杂志文章,评审
doi：10.1055/s-2002-19889
更新日期：2002-02-01 00:00:00
