Double-blind evaluation of a lignocaine-prilocaine cream (EMLA) in children. Effect on the pain associated with venous cannulation.

abstract：BACKGROUND:Entrustable professional activities (EPAs) are commonly developed by senior clinicians and education experts. However, if postgraduate training is conceptualised as an educational alliance, the perspective of trainees should be included. This raises the question as to whether the views of trainees and superv...

journal_title：British journal of anaesthesia

authors： Marty AP,Schmelzer S,Thomasin RA,Braun J,Zalunardo MP,Spahn DR,Breckwoldt J

更新日期：2020-07-01 00:00:00

abstract：:We have investigated the effects of 9.5% and 14.1% MAC concentrations of isoflurane on some psychometric measurements. Both concentrations depressed peak saccadic velocity (P < 0.01), choice reaction time (P < 0.05) and visual analogue scores for sedation (P < 0.05), but not the critical flicker fusion threshold. The ...

journal_title：British journal of anaesthesia

authors： Yoshizumi J,Marshall RW,Sanders LD,Vickers MD

更新日期：1993-12-01 00:00:00

abstract：:Methodology for assessment of depth of anaesthesia based on analysis of the electroencephalogram (EEG) is controversial. Techniques range from display of single measures, for example median value of the frequency spectrum, to dedicated pattern recognition systems based on measures of several EEG features. We have comp...

journal_title：British journal of anaesthesia

authors： Thomsen CE,Prior PF

更新日期：1996-08-01 00:00:00

abstract：BACKGROUND:Dexmedetomidine has been proposed as a perineural local anaesthetic (LA) adjunct to prolong peripheral nerve block duration; however, results from our previous meta-analysis in the setting of brachial plexus block (BPB) did not support its use. Many additional randomized trials have since been published. We ...

journal_title：British journal of anaesthesia

authors： Vorobeichik L,Brull R,Abdallah FW

更新日期：2017-02-01 00:00:00

abstract：BACKGROUND:Supraglottic airways (SGAs) have an established role in airway management of difficult airways in both adults and children. However, there are limited data regarding the use of SGAs for primary airway management in children. The aim of this study is to assess the success rates and adverse events related to t...

journal_title：British journal of anaesthesia

authors： Jagannathan N,Sequera-Ramos L,Sohn L,Wallis B,Shertzer A,Schaldenbrand K

更新日期：2014-04-01 00:00:00

abstract：BACKGROUND:Hip fracture is a condition with high mortality and morbidity in elderly frail patients. Intraoperative fluid optimization may be associated with benefit in this population. We investigated whether intraoperative fluid management using pulse-contour analysis cardiac monitoring, compared with standard care in...

journal_title：British journal of anaesthesia

authors： Moppett IK,Rowlands M,Mannings A,Moran CG,Wiles MD,NOTTS Investigators.

更新日期：2015-03-01 00:00:00

abstract：:Riluzole modulates several transmitter systems which may be involved in nociception. Antinociceptive effects have been shown in animal studies, but there are no human data. Therefore, we have examined the acute analgesic effect of riluzole in a human model of inflammatory pain induced by a thermal injury on the distal...

journal_title：British journal of anaesthesia

authors： Hammer NA,Lillesø J,Pedersen JL,Kehlet H

更新日期：1999-05-01 00:00:00

abstract：BACKGROUND:Fluid administration to increase stroke volume index (SVi) is a cornerstone of haemodynamic resuscitation. We assessed the accuracy of SVi variation during a calibrated abdominal compression manoeuvre (ΔSVi-CAC) to predict fluid responsiveness in children. METHODS:Patients younger than 8 yr with acute circu...

journal_title：British journal of anaesthesia

authors： Jacquet-Lagrèze M,Tiberghien N,Evain JN,Hanna N,Courtil-Teyssedre S,Lilot M,Baudin F,Chardonnal L,Bompard D,Koffel C,Portefaix A,Javouhey E,Fellahi JL

更新日期：2018-12-01 00:00:00

abstract：:We report the successful preoperative control and anaesthetic management of severe hypertension in a 7-month-old baby with nephroblastoma and increased renin activity. The strategy for selection of appropriate antihypertensive pharmacological agents and the anaesthetic implications and management of the condition are ...

journal_title：British journal of anaesthesia

authors： Charlton GA,Sedgwick J,Sutton DN

更新日期：1992-08-01 00:00:00

abstract：:A retrospective study of serious non-fatal complications of extradural block in obstetric practice was carried out using a postal questionnaire. Two hundred and three obstetric units in the United Kingdom (responsible for 2,580,000 deliveries from 1982 to 1986 inclusive) responded. A total of 505,000 extradural blocks...

journal_title：British journal of anaesthesia

authors： Scott DB,Hibbard BM

更新日期：1990-05-01 00:00:00

abstract：:Muscle fasciculations and pain following the administration of suxamethonium were assessed in a group of patients who performed a series of stretch exercises approximately 1 h before operation. Comparison was made with a group who received suxamethonium but no pretreatment. Fasciculations were significantly reduced in...

journal_title：British journal of anaesthesia

authors： Magee DA,Robinson RJ

更新日期：1987-05-01 00:00:00

abstract：:In theory, setting an infrared multi-gas analyser to measure a volatile anaesthetic different from that in the sampled gas mixture may cause interference with carbon dioxide and nitrous oxide readings. The theory was investigated during evaluation of the Dräger Cicero EM anaesthetic workstation for the Medical Devices...

journal_title：British journal of anaesthesia

authors： Wilkes AR,Mapleson WW

更新日期：1996-05-01 00:00:00

abstract：:We have investigated the value of lower oesophageal contractility (LOC) in detecting awareness during anaesthesia in 20 human volunteer patients. LOC was measured either with subjects awake or after induction with propofol, during induction with propofol, and then as consciousness returned. Statistically significant c...

journal_title：British journal of anaesthesia

authors： Isaac PA,Rosen M

更新日期：1990-09-01 00:00:00

abstract：:A case of an infant receiving orthotopic heart transplantation with over-sized donor heart was reported. Left lower pulmonary venous obstruction after sternotomy closure was detected by transoesophageal echocardiography (TOE) and the decision to delay sternal closure was made and the clinical outcome was very satisfac...

journal_title：British journal of anaesthesia

authors： Lin CP,Chan KC,Chou YM,Wang MJ,Tsai SK

更新日期：2002-04-01 00:00:00

abstract：BACKGROUND:We describe a practical method of training anaesthetists in the technique of awake fibreoptic intubation. This is performed on a training course using the delegates as subjects. METHODS:The first 15 subjects underwent cardiovascular monitoring during airway fibreoptic endoscopy performed by other course mem...

journal_title：British journal of anaesthesia

authors： Patil V,Barker GL,Harwood RJ,Woodall NM

更新日期：2002-10-01 00:00:00

abstract：:The water soluble benzodiazepine midazolam was compared with diazepam, in doses of 0.07 mg kg-1 and 0.15 mg kg-1 respectively, administered i.v. to 100 patients undergoing gastroscopy. The degree of sedation, ease of endoscopy and recovery were comparable in the two groups. The effects of both drugs on arterial pressu...

journal_title：British journal of anaesthesia

authors： Whitwam JG,Al-Khudhairi D,McCloy RF

更新日期：1983-08-01 00:00:00

abstract：:The identification of a serum marker to assist in the diagnosis of cerebral injury after cardiac surgery is potentially useful. S100 protein is an early marker of cerebral damage. It is released after cardiac surgery performed under cardiopulmonary bypass (CPB). Its level is correlated with the duration of CPB, deep c...

journal_title：British journal of anaesthesia

authors： Ali MS,Harmer M,Vaughan R

更新日期：2000-08-01 00:00:00

abstract：:We describe a six-compartment physiological model of the kinetics and dynamics of induction of anaesthesia with propofol in sheep. It includes a faithful description of initial bolus kinetics caused by accurate representations of the inter-relationships between initial vascular mixing, lung kinetics and cardiac output...

journal_title：British journal of anaesthesia

authors： Upton RN,Ludbrook GL

更新日期：1997-10-01 00:00:00

abstract：:Percutaneous tracheostomy is being used increasingly in the intensive care unit and endoscopic control of this procedure affords an improved level of safety. Training in such new minimal access techniques can be a significant risk factor in patient outcome. Surgical simulation provides training which minimizes this ri...

journal_title：British journal of anaesthesia

authors： Gardiner Q,White PS,Carson D,Shearer A,Frizelle F,Dunkley P

更新日期：1998-09-01 00:00:00

abstract：BACKGROUND:Pressure recording analytical method (PRAM) is a novel, arterial pulse contour-based method for measuring cardiac output (CO). Validation studies of PRAM in children are few, and have not assessed both absolute accuracy and ability to track changes in CO across a broad case mix. We aimed to compare CO as mea...

journal_title：British journal of anaesthesia

authors： Saxena R,Durward A,Puppala NK,Murdoch IA,Tibby SM

更新日期：2013-03-01 00:00:00

abstract：:We have studied 16 healthy volunteers whose lungs were preoxygenated six times each in order to assess the amount of room air entrained during tidal volume preoxygenation if a good seal is not maintained between the face mask and the face. With a fresh gas flow of 10 litre min-1, we found that using gravity alone to h...

journal_title：British journal of anaesthesia

authors： McGowan P,Skinner A

更新日期：1995-12-01 00:00:00

abstract：:The physical and pharmacological properties of the structural isomers isoflurane and enflurane differ from each other and from those of other potent inhaled anaesthetics. The minimum alveolar concentration (MAC) for isoflurane (1.15%) is one-and-one-half times that for halothane (0.75%) and two-thirds that for enflura...

journal_title：British journal of anaesthesia

authors： Eger EI 2nd

更新日期：1984-01-01 00:00:00

abstract：:Clevidipine is a new vascular-selective, calcium channel antagonist of the dihydropyridine type with an ester side chain susceptible to esterase metabolism. In healthy volunteers, it has high clearance (0.069 litres min-1 kg-1) with a small volume of distribution at steady state (0.19 litres kg-1). The half-lives of t...

journal_title：British journal of anaesthesia

authors： Vuylsteke A,Milner Q,Ericsson H,Mur D,Dunning J,Jolin-Mellgård A,Nordlander M,Latimer R

更新日期：2000-11-01 00:00:00

abstract：:Integrated electromyographic studies in burned patients, and in normal controls, during the administration of small doses of suxamethonium (0.1 or 0.2 mg kg-1) have shown that the level of paralysis and the duration of paralysis are significantly increased in burn patients and that the effect is greater with larger bu...

journal_title：British journal of anaesthesia

authors： Brown TC,Bell B

更新日期：1987-08-01 00:00:00

abstract：:Five-year survival following cardiac transplantation approaches 50% and such patients occasionally present for non-cardiac surgery. The application of a simple general anaesthetic technique is described in a patient undergoing minor surgery, and the problems involved in managing heart transplant recipients are discuss...

journal_title：British journal of anaesthesia

authors： Bricker SR,Sugden JC

更新日期：1985-06-01 00:00:00

abstract：:To determine if improved postoperative recovery in surgical inpatients receiving intraoperative therapeutic suggestions are applicable in an outpatient population, 70 consenting, unpremedicated adults undergoing elective outpatient hernia repair under general anaesthesia were allocated randomly to either a therapeutic...

journal_title：British journal of anaesthesia

authors： Lebovits AH,Twersky R,McEwan B

更新日期：1999-06-01 00:00:00

abstract：:Six male patients were studied on the morning following upper abdominal surgery for highly selective vagotomy. Nalbuphine hydrochloride was infused i.v. at different rates that increased progressively in each hour over a 4-h period. In the last 15 min of each hour, the plasma nalbuphine concentrations were almost stea...

journal_title：British journal of anaesthesia

authors： Pugh GC,Drummond GB

更新日期：1987-11-01 00:00:00

abstract：:The effects of bolus doses of phenoperidine 1-2 mg i.v. either alone, or combined with pancuronium 2-4 mg, were investigated in seven patients in traumatic coma. Phenoperidine alone significantly reduced mean arterial pressure (MAP) by a mean (+/- SEM) of 13.2 (+/- 2.8) mm Hg. Overall there was no significant change i...

journal_title：British journal of anaesthesia

authors： Bingham RM,Hinds CJ

更新日期：1987-05-01 00:00:00

abstract：:Studies with an emulsion formulation of ICI 35 868 (2,6- diisopropylphenol ) indicate that this new formulation has anaesthetic properties in rats and mice, and haemodynamic effects in the mini-pig which are similar to those of the previously available Cremophor formulation. Administration of the emulsion formulation ...

journal_title：British journal of anaesthesia

authors： Glen JB,Hunter SC

更新日期：1984-06-01 00:00:00

abstract：OBJECTIVES:To evaluate the effects of phosphodiesterase type III and V (PDEIII and PDEV) inhibition on pulmonary and systemic haemodynamics in a porcine model of acute pulmonary hypertension. METHODS:Twenty-four adult swine were anaesthetized with 1 MAC isoflurane and mechanically ventilated with an FI(O(2)) of 100%. ...

journal_title：British journal of anaesthesia

authors： Lobato EB,Beaver T,Muehlschlegel J,Kirby DS,Klodell C,Sidi A

更新日期：2006-03-01 00:00:00