Abstract:
:Zn++ in combination with hexetidine exerts a synergistic plaque inhibition. Studies in our laboratory on the mechanism of this effect suggested that Cu++ and hexetidine may have a similar combination effect. This hypothesis was tested in vivo on a human test panel in a double-blind crossover study. The amount of Cu++ retained by plaque bacteria in vitro was also evaluated. Seven volunteers rinsed with the solutions for 1 min twice daily for 5 days. The test solutions were H2O, 1.0 mM CuSO4, 2.0 mM hexetidine, and the last two in combination. During the test period no oral hygiene was allowed, and sucrose-containing chewing gum was used to enhance plaque formation. The plaque index scores after rinsing with the combination were significantly (p less than 0.05) lower than those of the other solutions. The effect of hexetidine on Cu++ retention in plaque bacteria was evaluated in plaque samples (n = 3) grown anaerobically overnight in PPLO medium. The bacteria were washed five times, digested in concentrated HNO3, and Cu++ determined by atomic absorption. The presence of hexetidine resulted in a significantly greater amount of Cu++ retained by bacteria at all CuSO4 concentrations. It is suggested that the nonpolar nature of the hexetidine molecule enables Cu++ bound to hexetidine to pass into the bacterial cell. Within the cell, Cu++ can interfere with bacterial metabolism, giving a reduction in plaque growth.
journal_name
Acta Odontol Scandjournal_title
Acta odontologica Scandinavicaauthors
Grytten J,Tollefsen T,Afseth Jdoi
10.3109/00016358709096368subject
Has Abstractpub_date
1987-12-01 00:00:00pages
429-33issue
6eissn
0001-6357issn
1502-3850journal_volume
45pub_type
临床试验,杂志文章abstract::Patients with chronic orofacial pain often undergo endodontic therapy or surgery in an attempt to eliminate or relieve their symptoms. This study examined the relationship among invasive dental treatment, pain reports, and disease conviction in a group of patients referred for pain management. Forty-eight patients ref...
journal_title:Acta odontologica Scandinavica
pub_type: 杂志文章
doi:10.3109/00016359509005943
更新日期:1995-02-01 00:00:00
abstract:OBJECTIVES:The present study addresses the effect of fluoride and sodium lauryl sulphate content of toothpaste on oral epithelial cells in vivo conditions. SUBJECTS AND METHOD:Forty volunteers were assigned into two experimental groups, each of them applying the different brand of toothpaste. Every group has been usin...
journal_title:Acta odontologica Scandinavica
pub_type: 杂志文章
doi:10.1080/00016357.2019.1577988
更新日期:2019-07-01 00:00:00
abstract::This randomized clinical trial was initiated to study the effect of two restorative procedures on the clinical quality and longevity of class-III resin restorations. The material consisted of 52 pairs of class-III restorations in the microfilled resin Silar completed with two modifications of the conventional acid-etc...
journal_title:Acta odontologica Scandinavica
pub_type: 临床试验,杂志文章,随机对照试验
doi:10.3109/00016359309040575
更新日期:1993-08-01 00:00:00
abstract:OBJECTIVES:Vinyl polysiloxane (VPS) is elastomeric dental impression material which, despite having very few reports of adverse reactions, has shown high levels of cytotoxicity that is difficult to be interpreted without referencing to the positive control material. Therefore, in this study, positive control VPS was de...
journal_title:Acta odontologica Scandinavica
pub_type: 杂志文章
doi:10.3109/00016357.2013.879996
更新日期:2014-11-01 00:00:00
abstract:OBJECTIVE:To assess the staining susceptibility of four acrylic resin (Ivostar, SR Vivodent PE, Major Dent, Integral) and a nanocomposite resin (Veracia) artificial teeth and to evaluate the stain removal efficacy of denture cleansers. MATERIALS AND METHODS:Sixty maxillary incisors of each brand (total = 300) were div...
journal_title:Acta odontologica Scandinavica
pub_type: 杂志文章
doi:10.3109/00016357.2014.913195
更新日期:2014-11-01 00:00:00
abstract:OBJECTIVE:This study was undertaken to determine the potential of dental adhesive products to induce mucosal irritation based on their ability to damage the blood vessels of the chorioallantoic membrane (CAM) in fertilized hen's egg. MATERIAL AND METHODS:Twenty-seven dental adhesive products (total 36 solutions) cover...
journal_title:Acta odontologica Scandinavica
pub_type: 杂志文章
doi:10.1080/00016350701589286
更新日期:2007-10-01 00:00:00
abstract::The efficacy of oral fluconazole versus nystatin was evaluated as a treatment modality for oral candidosis. Of the included patients (n = 60), two-thirds presented with an erythematous candidosis, and the others showed clinical signs compatible with a pseudomembranous candidosis. Predisposing factors were xerostomia (...
journal_title:Acta odontologica Scandinavica
pub_type: 临床试验,杂志文章,随机对照试验
doi:10.1080/00016359850142790
更新日期:1998-08-01 00:00:00
abstract::Changes in the distribution of caries in economically developed nations over the last 15-20 years include 1) an overall decline in prevalence and severity in child populations; 2) an increasingly skewed distribution, with most disease now found in a small number of children; and 3) concentration of caries in pit and f...
journal_title:Acta odontologica Scandinavica
pub_type: 杂志文章
doi:10.1080/000163598422956
更新日期:1998-06-01 00:00:00
abstract:OBJECTIVE:To investigate the failure of 15 dental implants (Paragon/Zimmer) in relation to their surface quality. MATERIALS AND METHODS:The study comprised of 15 dental implants (7 mm D Advent Implant, 3.9 mm D apex design implant), which were followed from surgery to completion of prosthetic restorations. The implant...
journal_title:Acta odontologica Scandinavica
pub_type: 杂志文章
doi:10.3109/00016357.2011.569507
更新日期:2011-11-01 00:00:00
abstract::Sucking habits and their connection with family background was investigated in 3-year-old Finnish children. The association between sucking habits and malocclusion was also studied. The study was based on a survey with stratified randomized cluster sampling, confidential questionnaires, and clinical dental examination...
journal_title:Acta odontologica Scandinavica
pub_type: 杂志文章
doi:10.3109/00016359309041144
更新日期:1993-02-01 00:00:00
abstract:OBJECTIVE:The aim of the current study was to investigate the presence of sulphate-reducing bacteria (SRB) in human saliva and correlate with oral and systemic conditions. METHODS:Saliva samples were collected from 118 patients and inoculated in 2 ml of modified Postgate's E medium culture. After 28 days of incubation...
journal_title:Acta odontologica Scandinavica
pub_type: 杂志文章
doi:10.3109/00016357.2013.770163
更新日期:2013-11-01 00:00:00
abstract::Fifty-one patients (mean age, 47.3 years) with moderate to severe periodontal disease and 40 patients (mean age, 48.9 years) with symptoms related to bruxism (occlusal parafunctions such as grinding and/or clenching of the teeth) were compared with regard to periodontal conditions and signs and symptoms of mandibular ...
journal_title:Acta odontologica Scandinavica
pub_type: 杂志文章
doi:10.3109/00016358709097536
更新日期:1987-08-01 00:00:00
abstract::The aim of this study was to elucidate whether a premaxilla with a supernumerary tooth has additional dental abnormalities. The study does not include premaxillas with a mesiodens, only premaxillas with parasagittally located supernumerary teeth. Radiographs from eight children, followed from 1 year and 5 months to 11...
journal_title:Acta odontologica Scandinavica
pub_type: 杂志文章
doi:10.1080/00016350310008634
更新日期:2004-02-01 00:00:00
abstract:OBJECTIVE:The aim of this review was to summarize our present knowledge about calcium phosphate (CaP) coatings on implants with respect to their topographical appearance at micrometer as well as nanometer level and also the reported influence on bone healing. MATERIAL AND METHODS:The PubMed database was used with the ...
journal_title:Acta odontologica Scandinavica
pub_type: 杂志文章,评审
doi:10.1080/00016350903188325
更新日期:2009-01-01 00:00:00
abstract:OBJECTIVE:We aimed to determine the clinical effects of titanium-prepared, platelet-rich fibrin (T-PRF) on human palatal mucosal wound healing (PMWH) and to identify its effect on time-dependent changes in palatal soft-tissue thickness (PSTT) in terms of histoconduction, which is a new concept. MATERIALS AND METHODS:F...
journal_title:Acta odontologica Scandinavica
pub_type: 杂志文章,随机对照试验
doi:10.1080/00016357.2016.1219045
更新日期:2016-10-01 00:00:00
abstract::The aim of this study was to obtain data on local fluoride supply, dental attendance, and dental care habits in two sociologically similar municipalities with optimal, 1.0 ppm, and low, 0.3 ppm, water fluoride concentrations, respectively. The participants in the study were 30- to 40-year-old lifetime residents in the...
journal_title:Acta odontologica Scandinavica
pub_type: 杂志文章
doi:10.3109/00016359109005901
更新日期:1991-06-01 00:00:00
abstract::Three groups of extracted human teeth were sectioned longitudinally into experimental and control halves. The enamel surfaces of the three groups of teeth were pretreated with 37% H3PO4 for 1 min, 0.5 M NaClO3 for 2 h, or water rinsing for 10 min. The experimental halves of the three groups received an application of ...
journal_title:Acta odontologica Scandinavica
pub_type: 杂志文章
doi:10.3109/00016359609003538
更新日期:1996-10-01 00:00:00
abstract::Occlusar carious lesions from human molars, preserved in continuous humidity after extraction, were removed using conventional clinical techniques. Bacteriological samples were taken after rinsing the cavity with water only, after experimentally infecting the cavity and after treating uninfected cavities either with a...
journal_title:Acta odontologica Scandinavica
pub_type: 杂志文章
doi:10.3109/00016357709064125
更新日期:1977-01-01 00:00:00
abstract::Ceramic inlays offer a good alternative to posterior composites, which still show a high polymerization shrinkage. The thin cement layer will reduce the total amount of shrinkage and probably result in a better marginal adaptation and decreased marginal leakage. Fired feldspathic ceramic inlays cemented with either a ...
journal_title:Acta odontologica Scandinavica
pub_type: 杂志文章
doi:10.3109/00016359409027588
更新日期:1994-06-01 00:00:00
abstract::Our aim was to determine whether masseter muscle (M) and plasma (P) levels of prostaglandin E2 (PGE2) or leukotriene B4 (LTB4) are influenced by local glucocorticoid administration and whether such changes would be associated with corresponding changes in local pain or hyperalgesia. Eighteen patients with fibromyalgia...
journal_title:Acta odontologica Scandinavica
pub_type: 杂志文章
doi:10.1080/000163502753471970
更新日期:2002-01-01 00:00:00
abstract:OBJECTIVE:Polypharmacy is a common cause of xerostomia. This study aimed to investigate whether xerostomia could be an adverse drug event of mouthwashes, when they are used for longer than 2 weeks by patients taking polypharmacy. MATERIALS AND METHODS:This cross-sectional observational study included 120 hospitalized ...
journal_title:Acta odontologica Scandinavica
pub_type: 杂志文章
doi:10.3109/00016357.2014.923108
更新日期:2015-05-01 00:00:00
abstract::The effect of a vegetarian diet on oral health status could be manifold, but reports have so far mainly appeared from within Western populations. This study reports the oral health status of southeast Indian vegetarians, obtained by means of a questionnaire, clinical examination, and study cast evaluations. The materi...
journal_title:Acta odontologica Scandinavica
pub_type: 杂志文章
doi:10.3109/00016359609003508
更新日期:1996-02-01 00:00:00
abstract::The influence of different clinical variables on the marginal degradation of amalgam restorations was studied in a clinical trial of class-II amalgam restorations. Seven Scandinavian dentists using 5 different alloys placed 468 restorations in 210 patients. The marginal degradation was scored on impressions of the res...
journal_title:Acta odontologica Scandinavica
pub_type: 临床试验,杂志文章
doi:10.3109/00016359009029069
更新日期:1990-12-01 00:00:00
abstract:OBJECTIVE:The purpose of this study was to examine the effects of a dentifrice containing 5% calcium sodium phosphosilicate (CSP) on the remineralization of the enamel using optical coherence tomography (OCT). MATERIALS AND METHODS:Bovine incisors were sliced and shaped in a rectangular form. One group of five specime...
journal_title:Acta odontologica Scandinavica
pub_type: 杂志文章
doi:10.1080/00016357.2016.1277588
更新日期:2017-04-01 00:00:00
abstract:OBJECTIVE:To evaluate the effectiveness of the color change of hybrid light-emitting diode (LED) and low-intensity infrared diode laser devices for activating dental bleaching and to verify the occurrence of a color regression with time. MATERIAL AND METHODS:A total of 180 specimens obtained from human premolars were ...
journal_title:Acta odontologica Scandinavica
pub_type: 杂志文章
doi:10.3109/00016357.2010.549503
更新日期:2011-05-01 00:00:00
abstract:OBJECTIVE:The aim was to investigate the relationship between soft drink consumption, oral health and some lifestyle factors in Swedish adolescents. MATERIALS AND METHODS:A clinical dental examination and a questionnaire concerning lifestyle factors, including drinking habits, oral hygiene, dietary consumption, physic...
journal_title:Acta odontologica Scandinavica
pub_type: 杂志文章
doi:10.3109/00016357.2014.946964
更新日期:2014-11-01 00:00:00
abstract::The purpose of this study was to obtain data on the oral hygiene practices, oral hygiene status, and periodontal health among primary school children in Nairobi. The study group consisted of 513 children, 262 aged 6-8 years and 251 aged 13-15 years. The children were from 6 schools randomly selected among the 154 publ...
journal_title:Acta odontologica Scandinavica
pub_type: 杂志文章
doi:10.3109/00016359109005923
更新日期:1991-10-01 00:00:00
abstract::Three different methods were used to determine working and setting times of periodontal dressings. The Gillmore needle and the rheometer employed were not suitable for recording setting reactions. A penetration test was found applicable for determination of working and setting times for all three dressings although th...
journal_title:Acta odontologica Scandinavica
pub_type: 杂志文章
doi:10.3109/00016357909004701
更新日期:1979-01-01 00:00:00
abstract:OBJECTIVE:The aim of this study was to evaluate the influence of coffee and red wine staining on tooth color during and after bleaching. MATERIALS AND METHODS:Blocks obtained from human molars were divided into 11 groups (n = 5) in accordance with the bleaching treatment-peroxide carbamide 10%, 15% or 20%-and in accor...
journal_title:Acta odontologica Scandinavica
pub_type: 杂志文章
doi:10.3109/00016357.2013.771404
更新日期:2013-11-01 00:00:00
abstract::Errors in questionnaire surveys are usually of one of two sources: non-responses or incorrect answers. The aim was to investigate the validity of a questionnaire survey and to estimate the respective bias of these answers. Of 9,283 subjects selected to receive a questionnaire by post, 3,949 (43%) responded, and, of th...
journal_title:Acta odontologica Scandinavica
pub_type: 杂志文章
doi:10.1080/000163599428643
更新日期:1999-10-01 00:00:00