Abstract：
:The effect of arsenic (As) exposure on genome-wide expression was examined in rice (Oryza sativa L., ssp. Indica). A group of defense and stress-responsive genes, transporters, heat-shock proteins, metallothioneins, sulfate-metabolizing proteins, and regulatory genes showed differential expression in rice seedlings challenged with arsenate (AsV) and arsenite (AsIII). AsV stress led to upregulation or downregulation of an additional set of genes in comparison to AsIII. Differential expression of several genes that showed the highest contrast in a microarray analysis was validated by following the quantitative changes in the levels of individual transcripts following challenge with AsV, AsIII, Cd, Cr, and Pb. Most of the selected genes responded to challenge by heavy metals such as arsenic. However, expression of one of the cytochrome P450 genes (Os01g43740) in rice root was induced by AsV but not by other heavy metals. Similarly, one glutaredoxin (Os01g26912) is expressed specifically in the AsIII-treated shoot.
journal_name
Chemospherejournal_title
Chemosphereauthors
Chakrabarty D,Trivedi PK,Misra P,Tiwari M,Shri M,Shukla D,Kumar S,Rai A,Pandey A,Nigam D,Tripathi RD,Tuli Rdoi
10.1016/j.chemosphere.2008.09.082subject
Has Abstractpub_date
2009-02-01 00:00:00pages
688-702issue
5eissn
0045-6535issn
1879-1298pii
S0045-6535(08)01236-8journal_volume
74pub_type
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