Abstract：
:A matched case-control study was conducted of 53 leukemia deaths and of 212 controls within a previously studied cohort of 24,545 on-shore workers employed between January 1, 1952 and August 15, 1977 at the Portsmouth (New Hampshire) Naval Shipyard. The study sought to ascertain a priori whether there was an association between leukemia deaths and occupational exposure to either ionizing radiation or organic solvents. To obtain information on individual exposures, radiation dose histories and detailed work histories by job and shop were evaluated for each subject. No statistically significant associations were found either between ionizing radiation or presumed solvent exposure and myelogenous or lymphatic leukemia. However, when specific job categories and shops were examined without benefit of a priori hypotheses, two occupations, electrician and welder, were found to be associated with leukemia. For electricians, the Mantel-Haenszel odds ratio (ORMH) was significantly elevated for all leukemias (ORMH = 3.00, 95% confidence interval (CI) = 1.29-6.98), particularly for lymphatic leukemia (ORMH = 6.00, 95% CI = 1.47-24.45). For welders, the odds ratio was not significantly elevated for all leukemias (ORMH = 2.25, 95% CI = 0.92-5.53), but was significantly elevated for myeloid leukemia (ORMH = 3.83, 95% CI = 1.28-11.46). These findings persisted when potential confounders were adjusted by means of a conditional logistic regression model.
journal_name
Am J Epidemioljournal_title
American journal of epidemiologyauthors
Stern FB,Waxweiler RA,Beaumont JJ,Lee ST,Rinsky RA,Zumwalde RD,Halperin WE,Bierbaum PJ,Landrigan PJ,Murray WE Jrdoi
10.1093/oxfordjournals.aje.a114350subject
Has Abstractpub_date
1986-06-01 00:00:00pages
980-92issue
6eissn
0002-9262issn
1476-6256journal_volume
123pub_type
杂志文章abstract：:The mortality experience of 8679 members of a metal trades union--men employed in shipyards, metal fabrication shops, small boat yards, and field construction--was studied from 1950 to 1976 by the historical prospective method. Relative to rates for US men of comparable age and race, the risk of death from all causes ...
journal_title：American journal of epidemiology
pub_type： 杂志文章
doi：
更新日期：1980-12-01 00:00:00
abstract：:Evidence on dietary risk factors for ovarian cancer is inconsistent, but some studies have suggested positive associations with dietary fat, lactose, and cholesterol and negative associations with green and yellow vegetable intake. By using information from the Iowa Women's Health Study, the authors investigated the a...
journal_title：American journal of epidemiology
pub_type： 杂志文章
doi：10.1093/oxfordjournals.aje.a009723
更新日期：1999-01-01 00:00:00
abstract：:Familial resemblance in the blood pressure response to sodium restriction in normotensive persons was investigated. Forty-four families of identical twin children participated in a sodium restriction (less than or equal to 75 meq/day) protocol for a period of 12 weeks. Subjects were residents of central Indiana, and t...
journal_title：American journal of epidemiology
pub_type： 杂志文章
doi：10.1093/oxfordjournals.aje.a114719
更新日期：1987-11-01 00:00:00
abstract：:The relation of adenocarcinoma of the facial sinuses and exposure to wood dust has been recognized for 20 years. As the tracheobronchial mucosa is similar to that lining the sinuses, a link between bronchial adenocarcinoma and wood dust exposure has been postulated. To test this hypothesis, a case-control study was co...
journal_title：American journal of epidemiology
pub_type： 杂志文章
doi：10.1093/oxfordjournals.aje.a115444
更新日期：1989-12-01 00:00:00
abstract：:We determined measurement properties of the Sedentary Time and Activity Reporting Questionnaire (STAR-Q), which was designed to estimate past-month activity energy expenditure (AEE). STAR-Q validity and reliability were assessed in 102 adults in Alberta, Canada (2009-2011), who completed 14-day doubly labeled water (D...
journal_title：American journal of epidemiology
pub_type： 杂志文章
doi：10.1093/aje/kwu150
更新日期：2014-08-15 00:00:00
abstract：:The association between cigarette smoking and inflammation is well known. However, the biological mechanisms behind the association are not fully understood, particularly the role of DNA methylation, which is known to be affected by smoking. Using 2-step epigenetic Mendelian randomization, we investigated the role of ...
journal_title：American journal of epidemiology
pub_type： 杂志文章
doi：10.1093/aje/kwx181
更新日期：2017-11-15 00:00:00
abstract：:Physical size at birth (primarily birth weight) is a key predictor of infant mortality and morbidity and may serve as a predictor of risk to chronic disease in adulthood. By use of birth records, it is sometimes possible to accumulate large, even massive, data sets that can permit analyses to separate genetic and envi...
journal_title：American journal of epidemiology
pub_type： 评论,杂志文章
doi：10.1093/aje/kwk106
更新日期：2007-04-01 00:00:00
abstract：:The authors examined the relation between 50 widely used agricultural pesticides and lung cancer incidence in the Agricultural Health Study, a prospective cohort study of 57,284 pesticide applicators and 32,333 spouses of farmer applicators with no prior history of lung cancer. Self-administered questionnaires were co...
journal_title：American journal of epidemiology
pub_type： 杂志文章
doi：10.1093/aje/kwh290
更新日期：2004-11-01 00:00:00
abstract：:The evolving concept of gender-based violence (GBV) is a multifaceted issue of public health significance. Until recently, most studies examining GBV have been conducted in North America. In this issue of the Journal, Palermo et al. (Am J Epidemiol. 2014;179(5):602-612) report their secondary analyses involving approx...
journal_title：American journal of epidemiology
pub_type： 评论,杂志文章
doi：10.1093/aje/kwt296
更新日期：2014-03-01 00:00:00
abstract：:Seventh-Day Adventists in Tromsø showed a coronary risk factor pattern similar to Seventh-Day Adventists in other parts of the world. Compared with non-Seventh-Day Adventists, serum cholesterol was 1.35 mmol/liter (1974) and 0.83 mmol/liter (1979-1980) lower in males and 0.64 mmol/liter (1979-1980) lower in females. B...
journal_title：American journal of epidemiology
pub_type： 杂志文章
doi：10.1093/oxfordjournals.aje.a114162
更新日期：1985-11-01 00:00:00
abstract：:There is an association between stress and dementia. However, less is known about dementia among persons with varied stress responses and sex differences in these associations. We used this population-based cohort study to examine dementia among persons with a range of clinician-diagnosed stress disorders, as well as ...
journal_title：American journal of epidemiology
pub_type： 杂志文章
doi：10.1093/aje/kwy269
更新日期：2019-03-01 00:00:00
abstract：:In this issue of the Journal, Van Ewijk et al. (Am J Epidemiol. 2013;177(8):729-736) report intriguing associations between prenatal exposure to the religious month of Ramadan and body anthropometry among adult Muslims in Indonesia. They categorized prenatal exposure according to the relative timing of Ramadan and the...
journal_title：American journal of epidemiology
pub_type： 评论,杂志文章
doi：10.1093/aje/kwt024
更新日期：2013-04-15 00:00:00
abstract：:The authors present results from a novel approach to understanding recent secular trends in overweight in terms of changes in underlying component distributions. On the basis of an examination of two large overlapping samples of Danish young men (ns = 16,557 and 21,747) spanning birth cohorts 1939-1958, the authors fo...
journal_title：American journal of epidemiology
pub_type： 杂志文章
doi：10.1093/oxfordjournals.aje.a115917
更新日期：1991-03-01 00:00:00
abstract：:In the Nepal Blindness Survey, 39,887 people in 105 sites were examined by 10 ophthalmologists from Nepal and four other countries during 1981. Ophthalmic protocols were pretested on approximately 3000 subjects; however, interobserver variability was inevitable. To quantify the amount of variability and assess the rel...
journal_title：American journal of epidemiology
pub_type： 杂志文章
doi：10.1093/oxfordjournals.aje.a113633
更新日期：1983-08-01 00:00:00
abstract：:In this paper, the authors present an objective system to evaluate interviewer performance for use in epidemiologic studies. With this quality control system, all study interviews are audio-taped, and a random sample of interviews are coded according to interviewer behaviors, such as whether the interviewer asked the ...
journal_title：American journal of epidemiology
pub_type： 杂志文章
doi：10.1093/oxfordjournals.aje.a117192
更新日期：1994-12-01 00:00:00
abstract：:High-fiber diets are associated with improved lipid profiles. However, pre- and postmenopausal women respond differently to fiber intake, suggesting that endogenous estradiol mediates the effect. The authors' objective was to determine the direct effect of fiber intake on lipoprotein cholesterol levels independent of ...
journal_title：American journal of epidemiology
pub_type： 杂志文章
doi：10.1093/aje/kwq388
更新日期：2011-01-15 00:00:00
abstract：:The present report evaluates a method for the determination of the maximal velocity of the outward sodium, potassium, chlorine (Na-K-Cl) cotransport in erythrocytes. The loading procedure was carried out using the ionophore nystatin. The technical error for this assay, based on concurrent analysis of randomized blind ...
journal_title：American journal of epidemiology
pub_type： 临床试验,杂志文章,随机对照试验
doi：10.1093/oxfordjournals.aje.a114602
更新日期：1987-05-01 00:00:00
abstract：:Eighty-eight cases with newly diagnosed carcinoma of the endometrium and 177 age-matched neighborhood controls were interviewed to test the hypothesis that exogenous estrogens lead to an increased risk of endometrial cancer. Forth-five per cent of the cases and 22% of the controls reported a history of estrogen use wh...
journal_title：American journal of epidemiology
pub_type： 杂志文章
doi：10.1093/oxfordjournals.aje.a113215
更新日期：1981-10-01 00:00:00
abstract：:The occurrence of cancer of the corpus uteri in Denmark is examined by the use of data from the Danish Cancer Registry. The study population consists of 14,149 cases diagnosed with cancer of the corpus uteri between 1943 and 1980. Since 1943, the incidence has been steadily increasing. The trend in the incidence rates...
journal_title：American journal of epidemiology
pub_type： 杂志文章
doi：10.1093/oxfordjournals.aje.a113793
更新日期：1984-05-01 00:00:00
abstract：:Studies have provided evidence of an inverse association between atopic allergic conditions (AACs) and invasive colorectal cancer (CRC) incidence and mortality in predominantly white populations. We examined the association between AACs (asthma, hay fever, or allergy) and CRC among white, African-American, Native Hawa...
journal_title：American journal of epidemiology
pub_type： 杂志文章
doi：10.1093/aje/kwu361
更新日期：2015-06-01 00:00:00
abstract：:Few studies have examined the role of endogenous sex hormones in breast cancer, and to the authors' knowledge, only two have done so prospectively. The authors report here the results of a prospective study based on an available bank of previously analyzed plasma collected in 1972-1974 from 442 women aged 50-79 years ...
journal_title：American journal of epidemiology
pub_type： 杂志文章
doi：10.1093/oxfordjournals.aje.a116228
更新日期：1992-06-01 00:00:00
abstract：:Several investigators have documented the effect of temperature on mortality, although fewer have studied its impact on morbidity. In addition, little is known about the effectiveness of mitigation strategies such as use of air conditioners (ACs). The authors investigated the association between temperature and hospit...
journal_title：American journal of epidemiology
pub_type： 杂志文章
doi：10.1093/aje/kwq231
更新日期：2010-11-01 00:00:00
abstract：:The association of asthma with occupational exposures was studied in 14,151 adults, aged 25-59 years, from the general population of the 1975 French Pollution Atmospherique et Affections Respiratoires Chroniques (PAARC) Survey. Associations of asthma with specific jobs, such as personal care workers, waiters, and stoc...
journal_title：American journal of epidemiology
pub_type： 杂志文章
doi：10.1093/aje/kwh316
更新日期：2004-12-01 00:00:00
abstract：:The human immunodeficiency virus (HIV) epidemic among adolescent girls and young women (AGYW) in sub-Saharan Africa is a critical public health problem. We assessed whether depressive symptoms in AGYW were longitudinally associated with incident HIV, and identified potential social and behavioral mediators. Data came ...
journal_title：American journal of epidemiology
pub_type： 杂志文章,随机对照试验
doi：10.1093/aje/kwz238
更新日期：2020-05-05 00:00:00
abstract：:Administration of pain relievers has been associated with both lower and higher risks of adverse reproductive outcomes in animals. In the sole investigation of male pain-reliever use and human fertility carried out to date, Smarr et al. (Hum Reprod. 2016;31(9):2119-2127) found a 35% reduction in fecundability among ma...
journal_title：American journal of epidemiology
pub_type： 杂志文章
doi：10.1093/aje/kwaa096
更新日期：2020-11-02 00:00:00
abstract：:Hearing impairment (HI) is prevalent, is modifiable, and has been associated with cognitive decline. We tested the hypothesis that audiometric HI measured in 2013 is associated with poorer cognitive function in 253 men and women from Washington County, Maryland (mean age = 76.9 years) in a pilot study carried out with...
journal_title：American journal of epidemiology
pub_type： 杂志文章
doi：10.1093/aje/kwu333
更新日期：2015-05-01 00:00:00
abstract：:The Baltimore-Washington Infant Study is a regional epidemiologic study of congenital heart disease. Among Infants born in the study area in 1981 and 1982, 664 had a diagnosis of congenital heart disease confirmed in the first year of life by echocardiography, cardiac catheterization, cardiac surgery, or autopsy. The ...
journal_title：American journal of epidemiology
pub_type： 杂志文章
doi：10.1093/oxfordjournals.aje.a113979
更新日期：1985-01-01 00:00:00
abstract：:The methods used for selecting subjects yield three types of case-control studies: 1) incident cases are compared to non-cases chosen to be representative of the exposure distribution among the person-years which produced the cases. In this type of study the exposure-odds ratio equals the incidence density ratio; 2) i...
journal_title：American journal of epidemiology
pub_type： 杂志文章
doi：10.1093/oxfordjournals.aje.a112614
更新日期：1978-09-01 00:00:00
abstract：:The authors conducted a simulation study to examine whether the race of a patient with end-stage renal disease (ESRD) influences the diagnosis of underlying kidney disease made by the nephrologist. The hypothesis was that ESRD may be more readily ascribed to hypertension in blacks than in whites. Nephrologists practic...
journal_title：American journal of epidemiology
pub_type： 临床试验,杂志文章,随机对照试验
doi：10.1093/oxfordjournals.aje.a117338
更新日期：1995-01-01 00:00:00
abstract：:Rabies virus was isolated by cell culture from the brains of 104 confirmed rabies cases diagnosed by the fluorescent-antibody staining technique in the United States during 1974-1984. Eighty-seven isolates were obtained from wild-life species, 10 from humans, and seven from domestic animals. These isolates were tested...
journal_title：American journal of epidemiology
pub_type： 杂志文章
doi：10.1093/aje/126.2.298
更新日期：1987-08-01 00:00:00
