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Differences between early and late-onset Alzheimer's disease.

Abstract：

:Alzheimer's disease of early onset versus that of late onset represent different syndromes, with distinct neuropathologies. Patients with early onset disease exhibit a more severe and more widespread loss of neurons from cortical and sub-cortical regions and the neurochemical changes involve not only the cholinergic system, but also neurons containing GABA, somatostatin and norepinephrine.

journal_name

Neurobiol Aging

journal_title

Neurobiology of aging

authors

Iversen LL

doi

10.1016/0197-4580(87)90132-1

subject

Has Abstract

pub_date

1987-11-01 00:00:00

pages

554-5

issue

6

eissn

0197-4580

issn

1558-1497

pii

0197-4580(87)90132-1

journal_volume

8

pub_type

杂志文章

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