Abstract：
:Recent anatomic studies indicate that the nucleus paragigantocellularis (PGi), located in the rostral ventrolateral medulla, strongly innervates the locus coeruleus (LC) while no such input derives from the more caudally located lateral reticular nucleus (LRN). In the present study, focal electrical stimulation of the LC was used to antidromically activate neurons in the ventrolateral medulla. A substantial number of PGi neurons were antidromically driven from the ipsilateral LC, while antidromic activation was virtually absent in LRN. Furthermore, several physiologic properties of antidromically driven cells in PGi define two populations within this group of neurons afferent to LC. These findings provide physiologic confirmation of an anatomically identified input to LC.
journal_name
Brain Resjournal_title
Brain researchauthors
Ennis M,Aston-Jones Gdoi
10.1016/0006-8993(87)90510-5subject
Has Abstractpub_date
1987-11-10 00:00:00pages
275-82issue
2eissn
0006-8993issn
1872-6240pii
0006-8993(87)90510-5journal_volume
425pub_type
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