Investigation of detection limits for diffuse optical tomography systems: II. Analysis of slab and cup geometry for breast imaging.

abstract：:A mammogram is the standard modality used for breast cancer screening. Computer-aided detection (CAD) approaches are helpful for improving breast cancer detection rates when applied to mammograms. However, automated analysis of a mammogram often leads to inaccurate results in the presence of the pectoral muscle. There...

journal_title：Physics in medicine and biology

authors： Feudjio CK,Klein J,Tiedeu A,Colot O

更新日期：2013-12-07 00:00:00

abstract：:The classical Sievert integral method is a valuable tool for dose rate calculations around brachytherapy sources, combining simplicity with reasonable computational times. However, its accuracy in predicting dose rate anisotropy around 192Ir brachytherapy sources has been repeatedly put into question. In this work, we...

journal_title：Physics in medicine and biology

authors： Karaiskos P,Angelopoulos A,Baras P,Rozaki-Mavrouli H,Sandilos P,Vlachos L,Sakelliou L

更新日期：2000-02-01 00:00:00

abstract：:Several applications in nuclear medicine require absolute activity quantification of single photon emission computed tomography images. Obtaining a repeatable calibration factor that converts voxel values to activity units is essential for these applications. Because source preparation and measurement of the source ac...

journal_title：Physics in medicine and biology

authors： Anizan N,Wang H,Zhou XC,Wahl RL,Frey EC

更新日期：2015-02-07 00:00:00

abstract：:A parametric model for the x-ray linear attenuation coefficient is used to describe the compositional dependence of Hounsfield numbers measured by medical CT scanners. Measurements with materials of known density and composition, that span and evenly sample the compositional range of tissues, are written as linear sim...

journal_title：Physics in medicine and biology

authors： Midgley SM

更新日期：2014-12-07 00:00:00

abstract：:Temporal regularization plays a critical role in cardiac gated dynamic SPECT reconstruction, of which the goal is to obtain an image sequence from a single acquisition which simultaneously shows both cardiac motion and tracer distribution change over the course of imaging (termed 5D). In our recent work, we explored t...

journal_title：Physics in medicine and biology

authors： Niu X,Yang Y,King MA

更新日期：2012-09-07 00:00:00

abstract：:As automation in radiation oncology becomes more common, it is important to determine which algorithms are equivalent for a given workflow. Often, algorithm comparisons are performed in isolation; however, clinical context can provide valuable insight into the importance of algorithm features and error magnification i...

journal_title：Physics in medicine and biology

authors： Weppler S,Schinkel C,Kirkby C,Smith W

更新日期：2020-09-28 00:00:00

abstract：:An inflatable endorectal balloon (ERB) is often used during stereotactic body radiation therapy (SBRT) for treatment of prostate cancer in order to reduce both intrafraction motion of the target and risk of rectal toxicity. However, the ERB can exert significant force on the prostate, and this work assessed the impact...

journal_title：Physics in medicine and biology

authors： Jones BL,Gan G,Kavanagh B,Miften M

更新日期：2013-11-21 00:00:00

abstract：:In this work, a procedure, based on Monte Carlo techniques, to analyse the effect on the tumour control probability of the time interval between surgery and postoperative radiotherapy is presented. The approach includes the tumour growth as well as the survival of tumour cells undergoing fractionated radiotherapy. Bot...

journal_title：Physics in medicine and biology

authors： Al-Dweri FM,Guirado D,Lallena AM,Pedraza V

更新日期：2004-07-07 00:00:00

abstract：:Poly(vinyl alcohol) cryogel, PVA-C, is presented as a tissue-mimicking material, suitable for application in magnetic resonance (MR) imaging and ultrasound imaging. A 10% by weight poly(vinyl alcohol) in water solution was used to form PVA-C, which is solidified through a freeze-thaw process. The number of freeze-thaw...

journal_title：Physics in medicine and biology

authors： Surry KJ,Austin HJ,Fenster A,Peters TM

更新日期：2004-12-21 00:00:00

abstract：:In this work, we propose a framework for optimizing spectral CT imaging parameters and hardware design with regard to material classification tasks. Compared with conventional CT, many more parameters must be considered when designing spectral CT systems and protocols. These choices will impact material classification...

journal_title：Physics in medicine and biology

authors： Rigie DS,La Rivière PJ

更新日期：2016-06-21 00:00:00

abstract：:The imaging performance of a high-resolution preclinical micro-positron emission tomography (micro-PET) system employing liquid xenon (LXe) as the gamma-ray detection medium was simulated. The arrangement comprises a ring of detectors consisting of trapezoidal LXe time projection ionization chambers and two arrays of ...

journal_title：Physics in medicine and biology

authors： Miceli A,Glister J,Andreyev A,Bryman D,Kurchaninov L,Lu P,Muennich A,Retiere F,Sossi V

更新日期：2012-03-21 00:00:00

abstract：:Monte Carlo simulation with PENELOPE (version 2003) is applied to calculate Leksell Gamma Knife dose distributions for heterogeneous phantoms. The usual spherical water phantom is modified with a spherical bone shell simulating the skull and an air-filled cube simulating the frontal or maxillary sinuses. Different sim...

journal_title：Physics in medicine and biology

authors： Al-Dweri FM,Rojas EL,Lallena AM

更新日期：2005-12-07 00:00:00

abstract：:Accurate scatter correction is required to produce high-quality reconstructions of x-ray cone-beam computed tomography (CBCT) scans. This paper describes new scatter kernel superposition (SKS) algorithms for deconvolving scatter from projection data. The algorithms are designed to improve upon the conventional approac...

journal_title：Physics in medicine and biology

authors： Sun M,Star-Lack JM

更新日期：2010-11-21 00:00:00

abstract：:Monte Carlo simulations are used to investigate skin dose resulting from chest wall radiotherapy with bolus. A simple model of a female thorax is developed, which includes a 2 mm-thick skin layer. Two representative 6 MV source models are considered: a tangents source model consisting of a parallel opposed pair of med...

journal_title：Physics in medicine and biology

authors： Oliver PAK,Monajemi TT

更新日期：2020-08-11 00:00:00

abstract：:We developed an anatomy-guided 4D closed-form algorithm to directly reconstruct parametric images from projection data for (nearly) irreversible tracers. Conventional methods consist of individually reconstructing 2D/3D PET data, followed by graphical analysis on the sequence of reconstructed image frames. The propose...

journal_title：Physics in medicine and biology

authors： Tang J,Kuwabara H,Wong DF,Rahmim A

更新日期：2010-08-07 00:00:00

abstract：:Polymer gel dosimetry aims to provide three-dimensional images of radiation therapy dose distributions in irradiated aqueous gels. The first gels required manufacture in an oxygen-free environment, but later the MAGIC formulation was introduced, which could be made in normal atmospheric conditions. Here we report our ...

journal_title：Physics in medicine and biology

authors： Luci JJ,Whitney HM,Gore JC

更新日期：2007-05-21 00:00:00

abstract：:The biological mechanisms of platelet destruction must be correctly identified before platelet survival curves can be interpreted. This report develops a theory of platelet destruction which is compared with experiments performed on platelets labelled with the radioactive isotope 51Cr. Platelet destruction rate is a c...

journal_title：Physics in medicine and biology

authors： Trowbridge EA,Martin JF

更新日期：1983-12-01 00:00:00

abstract：:The purpose of this study is to investigate whether quality assurance (QA) for cone-beam computed tomography (CBCT) image rotation is necessary in order to ensure the accuracy of CBCT based image-guided radiation therapy (IGRT) and adaptive radiotherapy (ART). Misregistration of angular coordinates during CBCT acquisi...

journal_title：Physics in medicine and biology

authors： Ayan AS,Lin H,Yeager C,Deville C,McDonough J,Zhu TC,Anderson N,Bar Ad V,Lu HM,Both S

更新日期：2013-02-21 00:00:00

abstract：:To address the quality assurance (QA) of a MR-linac which is an MRI combined with a linear accelerator (linac), the traditional linac QA-tests need to be redesigned, since the presence of the static magnetic field in the MR-linac alters the electron trajectory. The latter causes the asymmetry in the dose kernel which ...

journal_title：Physics in medicine and biology

authors： van Zijp HM,van Asselen B,Wolthaus JW,Kok JM,de Vries JH,Ishakoglu K,Beld E,Lagendijk JJ,Raaymakers BW

更新日期：2016-02-07 00:00:00

abstract：:Contemporary imaging modalities can now provide the surgeon with high quality three- and four-dimensional images depicting not only normal anatomy and pathology, but also vascularity and function. A key component of image-guided surgery (IGS) is the ability to register multi-modal pre-operative images to each other an...

journal_title：Physics in medicine and biology

authors： Peters TM

更新日期：2006-07-21 00:00:00

abstract：:Although field area and object thickness are important parameters in comparisons of techniques for optimal reduction of scattered radiation to the image, they are in practice seldom varied. For this reason, we suggest that contrast degradation (CDF) and contrast improvement (CIF) factors be more frequently used and ap...

journal_title：Physics in medicine and biology

authors： Carlsson GA,Carlsson CA,Nielsen B,Persliden J

更新日期：1986-07-01 00:00:00

abstract：:Heating induced near deep brain stimulation (DBS) lead electrodes during magnetic resonance imaging with a 3 T transceive head coil was measured, modeled, and imaged in three cadaveric porcine heads (mean body weight = 85.47 ± 3.19 kg, mean head weight = 5.78 ± 0.32 kg). The effect of the placement of the extra-crania...

journal_title：Physics in medicine and biology

authors： Shrivastava D,Abosch A,Hughes J,Goerke U,DelaBarre L,Visaria R,Harel N,Vaughan JT

更新日期：2012-09-07 00:00:00

abstract：:The aim of this study was to develop a model exploiting artificial neural networks (ANNs) to correlate dosimetric and clinical variables with late rectal bleeding in prostate cancer patients undergoing radical radiotherapy and to compare the ANN results with those of a standard logistic regression (LR) analysis. 718 m...

journal_title：Physics in medicine and biology

authors： Tomatis S,Rancati T,Fiorino C,Vavassori V,Fellin G,Cagna E,Mauro FA,Girelli G,Monti A,Baccolini M,Naldi G,Bianchi C,Menegotti L,Pasquino M,Stasi M,Valdagni R

更新日期：2012-03-07 00:00:00

abstract：:The aim of the present work was to investigate how the native signal observed in the electron paramagnetic resonance (EPR) spectrum of tooth enamel and dentin is associated with the organic content of the two tissues. This was achieved by comparing the EPR native signal and the optical bands (Raman and infrared, IR) a...

journal_title：Physics in medicine and biology

authors： Fattibene P,Carosi A,De Coste V,Sacchetti A,Nucara A,Postorino P,Dore P

更新日期：2005-03-21 00:00:00

abstract：:Breast MRI is frequently performed prior to breast conserving surgery in order to assess the location and extent of the lesion. Ideally, the surgeon should also be able to use the image information during surgery to guide the excision and this requires that the MR image is co-registered to conform to the patient's pos...

journal_title：Physics in medicine and biology

authors： Ebrahimi M,Siegler P,Modhafar A,Holloway CM,Plewes DB,Martel AL

更新日期：2014-04-07 00:00:00

abstract：:Remission spectroscopy in living tissues can only be performed because scattering processes induce a pronounced amount of backscattered light. New types of scattering chambers were constructed in order to investigate the angular distribution of light intensities caused by scattering events typical for living tissues. ...

journal_title：Physics in medicine and biology

authors： Frank KH,Kessler M,Appelbaum K,Albrecht HP,Mauch ED

更新日期：1989-12-01 00:00:00

abstract：:Uncemented prosthetic joint implants used in orthopaedic surgery are usually coated with a porous surface to encourage bone ingrowth. Better contact between the endosteal bone and the porous surface improves ingrowth, and such contact may be increased if the joint further subsides into position in the first weeks foll...

journal_title：Physics in medicine and biology

authors： Berry E,Langkamer VG,Jackson PC,Snow M,Goddard PR,Wells PN

更新日期：1993-02-01 00:00:00

abstract：:A quantitative comparison of two full three-dimensional (3D) gel dosimetry techniques was assessed in a clinical setting: radiochromic gel dosimetry with an in-house developed optical laser CT scanner and polymer gel dosimetry with magnetic resonance imaging (MRI). To benchmark both gel dosimeters, they were exposed t...

journal_title：Physics in medicine and biology

authors： Vandecasteele J,De Deene Y

更新日期：2013-09-21 00:00:00

abstract：:Large blood vessels can produce steep temperature gradients in heated tissues leading to inadequate tissue temperatures during hyperthermia. This paper utilizes a finite difference scheme to solve the basic equations of heat transfer and fluid flow to model blood vessel cooling. Unlike previous formulations, heat tran...

journal_title：Physics in medicine and biology

authors： Kolios MC,Sherar MD,Hunt JW

更新日期：1995-04-01 00:00:00

abstract：:The trend towards conformal, intensity modulated radiotherapy treatments has established the need for a true integrating dosimeter. In traditional radiotherapy, radiographic film dosimetry is commonly used. The accuracy and reproducibility of film optical density as an indicator of dose is influenced by several variab...

journal_title：Physics in medicine and biology

authors： Suchowerska N,Hoban P,Butson M,Davison A,Metcalfe P

更新日期：2001-05-01 00:00:00