Sensitive voltammetric determination of rutin at an in situ plated lead film electrode.

Abstract:

:A highly sensitive sensor for the determination of rutin by adsorptive stripping voltammetry was described. It consists of a lead film modified glassy carbon electrode (LF/GCE). In the proposed procedure rutin was accumulated by adsorption on the lead film electrode and then during the stripping step a lead film and the accumulated rutin were oxidised. The electrochemical behaviour of rutin at the lead film electrode was investigated by square-wave voltammetry. In the optimal conditions the anodic peak currents (measured by square-wave voltammetry) increased linearly with the concentration of rutin in the range of 5 x 10(-10) to 1 x 10(-8)mol L(-1). The detection limit for rutin following 30s of accumulation time was equal to 2.5 x 10(-10) mol L(-1). The method was successfully applied to the determination of rutin content in the tablets without previous separation.

journal_name

J Pharm Biomed Anal

authors

Tyszczuk K

doi

10.1016/j.jpba.2008.11.022

subject

Has Abstract

pub_date

2009-02-20 00:00:00

pages

558-61

issue

2

eissn

0731-7085

issn

1873-264X

pii

S0731-7085(08)00635-3

journal_volume

49

pub_type

杂志文章