Abstract:
:A highly sensitive sensor for the determination of rutin by adsorptive stripping voltammetry was described. It consists of a lead film modified glassy carbon electrode (LF/GCE). In the proposed procedure rutin was accumulated by adsorption on the lead film electrode and then during the stripping step a lead film and the accumulated rutin were oxidised. The electrochemical behaviour of rutin at the lead film electrode was investigated by square-wave voltammetry. In the optimal conditions the anodic peak currents (measured by square-wave voltammetry) increased linearly with the concentration of rutin in the range of 5 x 10(-10) to 1 x 10(-8)mol L(-1). The detection limit for rutin following 30s of accumulation time was equal to 2.5 x 10(-10) mol L(-1). The method was successfully applied to the determination of rutin content in the tablets without previous separation.
journal_name
J Pharm Biomed Analjournal_title
Journal of pharmaceutical and biomedical analysisauthors
Tyszczuk Kdoi
10.1016/j.jpba.2008.11.022subject
Has Abstractpub_date
2009-02-20 00:00:00pages
558-61issue
2eissn
0731-7085issn
1873-264Xpii
S0731-7085(08)00635-3journal_volume
49pub_type
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journal_title:Journal of pharmaceutical and biomedical analysis
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journal_title:Journal of pharmaceutical and biomedical analysis
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