Abstract:
:Several lines of evidence show that metabolic syndrome represents an important therapeutic challenge for the forthcoming years. This is because of the epidemic burden of this multifaceted disease, the adverse impact on cardiovascular risk, as well as the problems posed in its management. This paper will provide an up-to-date report on metabolic syndrome and cardiometabolic risk, focusing in particular on the epidemiological profile of the disease, the impact on risk profile and target organ damage as well as some of the main pathophysiological features of the condition. The general therapeutic recommendations, provided by the 2007 European Society of Hypertension/European Society of Cardiology Guidelines, will be briefly discussed.
journal_name
Blood Pressjournal_title
Blood pressureauthors
Grassi G,Seravalle G,Quarti-Trevano F,Dell'Oro R,Bombelli M,Mancia Gdoi
10.1080/08037050802677695subject
Has Abstractpub_date
2009-01-01 00:00:00pages
7-16issue
1-2eissn
0803-7051issn
1651-1999pii
907861421journal_volume
18pub_type
杂志文章,评审相关文献
BLOOD PRESSURE文献大全abstract:OBJECTIVE:To determine the clinical profile and blood pressure (BP) control rates of anticoagulated patients with hypertension and atrial fibrillation (AF). METHODS:The PAULA study was a multicenter cross-sectional/retrospective observational study conducted throughout Spain. The study included patients with nonvalvul...
journal_title:Blood pressure
pub_type: 杂志文章,多中心研究
doi:10.1080/08037051.2017.1313094
更新日期:2017-10-01 00:00:00
abstract:OBJECTIVE:To investigate if young normotensive subjects with a familial history of essential hypertension (FHH) or young borderline-hypertensive (BHT) subjects have a defect endothelial function. METHODS:Fifteen young (26 +/- 4 years) healthy normotensive (115 +/- 8/71 +/- 6 mmHg) subjects with a FHH, 31 matched healt...
journal_title:Blood pressure
pub_type: 杂志文章
doi:10.1080/080370502320779485
更新日期:2002-01-01 00:00:00
abstract:AIMS:The purpose of the study was to assess the effect of percutaneous transluminal coronary angioplasty (PTCA) on plasma N-terminal pro-brain natriuretic peptide (NT-proBNP) level in hypertensive and normotensive subjects with and without systolic left ventricular dysfunction. METHODS AND RESULTS:Forty patients affec...
journal_title:Blood pressure
pub_type: 杂志文章
doi:10.1080/08037050600804814
更新日期:2006-01-01 00:00:00
abstract:OBJECTIVE:To compare the effects of amlodipine and candesartan on oxidized low-density lipoprotein (OxLDL), conjugated dienes (CD) and baseline diene conjugation in circulating low-density lipoproteins (LDL-BDC) level during antihypertensive treatment. METHODS:Forty-nine patients with untreated mild to moderate essent...
journal_title:Blood pressure
pub_type: 杂志文章,随机对照试验
doi:10.1080/08037050601037844
更新日期:2006-01-01 00:00:00
abstract::Low compliance to therapeutic regimens can have serious impact on patient health. A variety of technologies such as tablet dispensers and reminders has been developed to improve compliance. The aim of this study was to assess the acceptance of patients and physicians with regard to the functions and usefulness of a re...
journal_title:Blood pressure
pub_type: 杂志文章
doi:10.3109/08037050903289598
更新日期:2009-01-01 00:00:00
abstract:INTRODUCTION:Detection and treatment of left ventricular hypertrophy (LVH) in hypertension is important in order to reduce cardiovascular risk. The product of QRS voltage and duration (e.g. Cornell voltage-duration product; CorP), is a good marker of LVH and the current study was designed to determine the prevalence of...
journal_title:Blood pressure
pub_type: 杂志文章,多中心研究
doi:10.1080/08037050802059092
更新日期:2008-01-01 00:00:00
abstract::Medullipin I (Med I) is a vasodepressor prohormone which is continuously elaborated into the renal venous effluent (RVE) of isolated rat kidneys perfused under high pressure. We have improved the yield of Med I by substituting saline for the albumin perfusate previously reported; and considerably improved refinement b...
journal_title:Blood pressure
pub_type: 杂志文章
doi:10.3109/08037059409102295
更新日期:1994-11-01 00:00:00
abstract::Hypertensive patients who are at high risk of developing cardiovascular (CV) complications have become the focus of modern treatment guidelines. The choice of antihypertensive therapies in these patients should be evidence-based: in particular, there should be evidence of a beneficial impact on CV events in addition t...
journal_title:Blood pressure
pub_type: 杂志文章,评审
doi:10.1080/08037050211264
更新日期:2002-01-01 00:00:00
abstract:AIMS:To assess safety and efficacy of valsartan/amlodipine combination in hypertensive Taiwanese patients. METHODS:This 12-week, multi-center, prospective, observational, post-marketing study enrolled 1029 patients to receive valsartan/amlodipine combination alone or as add-on to other antihypertensives. Efficacy was ...
journal_title:Blood pressure
pub_type: 临床试验,杂志文章,多中心研究
doi:10.3109/08037051.2012.697629
更新日期:2012-07-01 00:00:00
abstract::One-thousand-four-hundred-and-fifty-three patients admitted to a teaching hospital, haemodynamically stable and not severely ill nor in significant pain, were interviewed within 48 h of admission and demographic data and a detailed drinking history were obtained. Supine blood pressures (BP) were recorded on the day fo...
journal_title:Blood pressure
pub_type: 杂志文章
doi:10.3109/08037059709061808
更新日期:1997-03-01 00:00:00
abstract::The aim of this study was to assess the associations between single nucleotide polymorphisms (SNPs) of the apelin and APJ (apelin receptor) genes and the risk of hypertension in people living in the south-east coastal area of China. A cross-sectional study involving 1031 participants was performed. Genotypes of the ap...
journal_title:Blood pressure
pub_type: 杂志文章
doi:10.3109/08037051.2016.1156905
更新日期:2016-08-01 00:00:00
abstract::In order to study the role of opioid receptors in two models of experimental hypertension the binding of 3H-naloxone to membranes prepared from discrete brain regions and spinal cord was determined. Renal hypertensive rats (RHR) were found to have a greater density of 3H-naloxone binding sites in the hippocampus and h...
journal_title:Blood pressure
pub_type: 杂志文章
doi:10.3109/08037059409102254
更新日期:1994-05-01 00:00:00
abstract::We wanted to investigate whether time to steady state was reached within 2 h of insulin infusion during isoglycemic hyperinsulinemic clamp, comparing the glucose uptake index (M/IG) with Bergman's insulin sensitivity index (Sip). We performed a 2-h oral glucose tolerance test and a 3-h isoglycemic hyperinsulinemic cla...
journal_title:Blood pressure
pub_type: 临床试验,杂志文章
doi:10.1080/080370599439580
更新日期:1999-01-01 00:00:00
abstract::In order to study the contribution of the nitric oxide (NO)-pathway to cholinergic vasodilatation in the resistance vessels of the human forearm, we infused acetylcholine (ACh; 0.1 1000 ng/kg/min) or methacholine (MCh; 0.1 A 100 ng/kg/min) in the presence of saline, the NO-scavenger and guanylate cyclase inhibitor met...
journal_title:Blood pressure
pub_type: 杂志文章
doi:10.3109/08037059609078071
更新日期:1996-11-01 00:00:00
abstract:AIM:Our aim was to study different levels of high blood pressure and normal blood pressure (reference) to calculate the hazard ratios (HRs) for cardiovascular and total mortality in men and women with adjustments for many covariates. METHODS:A health-screening program was offered to a population-based sample in Stockh...
journal_title:Blood pressure
pub_type: 杂志文章
doi:10.1080/08037050903013881
更新日期:2009-01-01 00:00:00
abstract:OBJECTIVE:To compare unattended blood pressure (BP) with two attended BP, with 24-h ambulatory (ABPM) and central BP measurements in hypertensive patients with (DMs) and without diabetes (HTs). METHODS:In the same hypertension clinic we evaluate 129 consecutive HTs (56% female, 59 + 16 yrs) and 91 DMs (62% female, 64 ...
journal_title:Blood pressure
pub_type: 杂志文章
doi:10.1080/08037051.2019.1568184
更新日期:2019-04-01 00:00:00
abstract:AIM:The purpose of this study was to evaluate the prevalence of home blood pressure (BP) measurement, the type of devices and accuracy in a large sample of hypertensive patients referred to hospital outpatient hypertension clinics. METHODS:Eight hundred and fifty-five consecutive treated hypertensive patients who atte...
journal_title:Blood pressure
pub_type: 杂志文章
doi:10.1080/08037050500210765
更新日期:2005-01-01 00:00:00
abstract::Candesartan is a new angiotensin II type 1 (AT 1 ) receptor blocker that produces more effective 24-h blood pressure lowering than losartan in hypertensive patients. In in vitro tissue preparations, candesartan displays insurmountable antagonism of the responses to angiotensin II. Both irbesartan and EXP-3174, the act...
journal_title:Blood pressure
pub_type: 杂志文章
doi:10.1080/080370500439245
更新日期:2000-01-01 00:00:00
abstract::BACKGROUND AND AIM. The ratio of deceleration time to early mitral wave velocity (mitral deceleration index, MDI) has been recently shown to predict cardiovascular events more precisely than deceleration time alone in human hypertension. Data, however, about the relationship of this parameter with cardiac structure ar...
journal_title:Blood pressure
pub_type: 杂志文章
doi:10.3109/08037051.2011.553926
更新日期:2011-08-01 00:00:00
abstract::Abstract Background. The relationship between the C-344T polymorphism of CYP11b2 gene and blood pressure (BP) is controversial. The present study aimed to investigate whether it was affected by environmental determinants in Chinese Mongolian population. Methods. A cross-sectional study was conducted between 2003 and 2...
journal_title:Blood pressure
pub_type: 杂志文章
doi:10.3109/08037051.2010.495859
更新日期:2010-12-01 00:00:00
abstract::The familial aggregation of hypertension is well documented. However, many studies on the familial predisposition have suffered from insufficient knowledge of parental blood pressure (BP). In the present study, the family history is defined according to parental data from two BP surveys conducted almost 30 years apart...
journal_title:Blood pressure
pub_type: 杂志文章
doi:10.3109/08037059209077668
更新日期:1992-12-01 00:00:00
abstract::Standardization of blood pressure (BP) measurement is important for both clinical and epidemiological purposes. The aim of the present study was to investigate early vs late morning measurements of BP and heart rate in healthy subjects. During the years 1972-75, healthy men aged 40-59 years (n = 2014) participated in ...
journal_title:Blood pressure
pub_type: 临床试验,杂志文章
doi:10.1080/080370502321095339
更新日期:2002-01-01 00:00:00
abstract::Ascending aortic blood pressure-derived indices were shown to be related to coronary atherosclerosis. However, no study so far has analyzed the relation between ascending aortic pulsatility and the extent of coronary atherosclerosis in normotensives. Therefore, the aim of the present analysis was to assess the relatio...
journal_title:Blood pressure
pub_type: 杂志文章
doi:10.1080/08037050701428125
更新日期:2007-01-01 00:00:00
abstract:OBJECTIVE:The aim of the present study was to determine if there is an association of different gene polymorphisms of renin-angiotensin system and left ventricular hypertrophy (LVH) in patients with essential hypertension (EH) in St Petersburg population. PATIENTS AND METHODS:We examined 156 patients (the mean age 49+...
journal_title:Blood pressure
pub_type: 杂志文章
doi:10.1080/080370501753182343
更新日期:2001-01-01 00:00:00
abstract::Plasma level of adrenaline has been reported to be elevated in borderline hypertension. However, its role in developing and maintaining hypertension is still not completely understood. This study aimed to estimate the role of plasma adrenaline in developing hypertension. Ten patients with borderline hypertension (BHT)...
journal_title:Blood pressure
pub_type: 杂志文章
doi:10.3109/08037059509077578
更新日期:1995-03-01 00:00:00
abstract::It has previously been documented that patients with obstructive sleep apnoea (OSA) have an abnormal blood pressure (pressor) response to acute hypoxia when awake. The relationship between hypoxic chemosensitivity and 24 h blood pressure in OSA is not known. Twenty-four hour ambulatory BP (ABP) was measured at 15 min ...
journal_title:Blood pressure
pub_type: 杂志文章
doi:10.3109/08037059409101521
更新日期:1994-03-01 00:00:00
abstract::We have previously shown that the angiotensin receptor blocker valsartan is associated with a lower incidence of new-onset type 2 diabetes than that with the calcium-channel antagonist amlodipine in the treatment of hypertensive patients at high cardiovascular risk. We have now investigated the benefits of valsartan v...
journal_title:Blood pressure
pub_type: 杂志文章,随机对照试验
doi:10.1080/08037050802169644
更新日期:2008-01-01 00:00:00
abstract::The effects of spirapril and isradipine on blood pressure, urinary albumin excretion and sodium-volume homeostasis in hypertensive insulin-dependent diabetic patients with nephropathy were assessed. Fifteen Type 1 diabetic patients aged 28-53 years with a diabetes duration of 19-37 years were studied. All had hyperten...
journal_title:Blood pressure
pub_type: 临床试验,杂志文章,随机对照试验
doi:10.3109/08037059309077172
更新日期:1993-12-01 00:00:00
abstract::Since there appear to be important interactions between mechanisms of salt-sensitive and carbohydrate-sensitive hypertension, the goal of this study was to evaluate the effects of greatly reducing dietary salt intake and removal of one kidney (to increase salt sensitivity) on the hemodynamic and metabolic responses to...
journal_title:Blood pressure
pub_type: 杂志文章
doi:10.3109/08037059509077589
更新日期:1995-05-01 00:00:00
abstract:BACKGROUND:Orthostatic hypotension (OH) is common amongst the older population and is associated with morbidity and mortality. We sought to investigate predictors of OH to assist the clinician in identifying patients at risk. METHODS AND RESULTS:Database of 2696 patients attending a transient ischaemic attack (TIA) cl...
journal_title:Blood pressure
pub_type: 杂志文章
doi:10.3109/08037051.2012.732780
更新日期:2013-04-01 00:00:00