Adrenomedullary and glycemic alterations following diverse stress in soft-shelled turtles Lissemys punctata punctata Bonnoterre.

abstract：:The secretory activity of the adrenal gland is mainly regulated by peptidergic hormones (ACTH, angiotensin II) and ions. However, there is now increasing evidence that local factors, including neuropeptides and neurotransmitters, can also participate in the control of adrenocortical cells. In particular, serotonin (5-...

journal_title：Endocrine research

authors： Delarue C,Contesse V,Lefebvre H,Lenglet S,Grumolato L,Kuhn JM,Vaudry H

更新日期：1998-08-01 00:00:00

abstract：:The mechanisms by which SF-1 (Steroidogenic Factor-1) and Dax-1 (Dosage-sensitive sex reversal-Adrenal hypoplasia congenita critical region on the X chromosome) dictate adrenal-specific transcriptional programs are the focus of this laboratory. SF-1-mediated transcription is upregulated by phosphorylation of serine 20...

journal_title：Endocrine research

authors： Babu PS,Bavers DL,Shah S,Hammer GD

更新日期：2000-11-01 00:00:00

abstract：:Basal serum concentrations of prolactin (PRL) and the elevation of serum PRL concentrations induced by the serotonergic agents, quipazine and 5-hydroxytryptophan (5-HTP) were suppressed in rats treated acutely with dexamethasone. Acute dexamethasone treatment did not alter the stimulation of PRL release produced by th...

journal_title：Endocrine research

authors： Passaro EA,Meltzer HY,Gudelsky GA

更新日期：1987-01-01 00:00:00

abstract：:X-linked adrenoleukodystrophy (X-ALD) is the most common peroxisomal disorder characterized by abnormal accumulation of saturated very long chain fatty acids in tissues and body fluids with predominance in brain white matter and adrenal cortex. The clinical phenotype is highly variable ranging from the severe childhoo...

journal_title：Endocrine research

authors： Gärtner J,Dehmel T,Klusmann A,Roerig P

更新日期：2002-11-01 00:00:00

abstract：OBJECTIVES:The aim of this study was to investigate the effect of pioglitazone on serum uric acid (UA) levels and several diabetic parameters in drug-naïve subjects with type 2 diabetes mellitus (T2DM). PATIENTS AND METHODS:The patients (n = 68) received 7.5-30 mg/day pioglitazone monotherapy. They were divided into t...

journal_title：Endocrine research

authors： Kutoh E,Hori T

更新日期：2013-08-01 00:00:00

abstract：:The adrenal cortex is a dynamic organ in which the cells of the outer cortex continually divide. It is well known that this cellular proliferation is dependent on constant stimulation from peptides derived from the ACTH precursor proopiomelanocortin (POMC) since disruption of pituitary corticotroph function results in...

journal_title：Endocrine research

authors： Bicknell AB

更新日期：2002-11-01 00:00:00

abstract：:A method is described for the preparation of high yields of viable, dissociated cells from porcine theca interna and corpus luteum and from human and bovine endometrium. The tissues were dissociated by incubation at 37 degrees C in a mixture of 0.5% collagenase, 0.1% hyaluronidase and 0.1% pronase in balanced salt sol...

journal_title：Endocrine research

authors： Marcus GJ,Connor L,Domingo MT,Tsang BK,Downey BR,Ainsworth L

更新日期：1984-01-01 00:00:00

abstract：:Immunohistochemistry using a StAR peptide antiserum had previously revealed strong staining in rat and bovine adrenal medulla, suggesting the presence of a protein immunogenically related to StAR. Western blots of bovine medulla tissue homogenates showed the principal adrenal medullary immuno-reactive species to have ...

journal_title：Endocrine research

authors： Lo YC,MacKenzie SM,Howie AF,Apps DK,Mason JI,Williams BC,Morley SD

更新日期：2000-11-01 00:00:00

abstract：:The question of whether ethanol's (ETOH's) known suppressive effect on serum luteinizing hormone (LH) could be mediated directly at the anterior pituitary level was addressed by examining the effects of ETOH in vitro on release of LH from cultured male rat pituitary cells. The impact of added ethanol concentrations ra...

journal_title：Endocrine research

authors： Emanuele MA,Tentler J,Emanuele NV,Reda D,Kirsteins L,Lawrence AM

更新日期：1989-01-01 00:00:00

abstract：:The recent cloning of a family of melanocortin receptors (MC-R) has identified five distinct G protein- and adenylate cyclase-coupled receptors. The MC2-receptor (MC2-R) preferentially binds ACTH. It is expressed in the adrenal cortex and is hence considered to be the ACTH receptor. The MC5-receptor (MC5-R) binds ACTH...

journal_title：Endocrine research

authors： Liakos P,Chambaz EM,Feige JJ,Defaye G

更新日期：1998-08-01 00:00:00

abstract：:Y1 adrenocortical tumor cells possess amplified and overexpressed c-Ki-ras proto-oncogene, displaying chronic high levels of the c-Ki-Ras-GTP protein. Despite this oncogenic lesion, we previously reported that Y1 cells retain tight regulatory mechanisms of cell cycle control typified by the mitogenic response triggere...

journal_title：Endocrine research

authors： Costa ET,Forti FL,Rocha KM,Moraes MS,Armelin HA

更新日期：2004-11-01 00:00:00

abstract：:Purpose: Transthyretin (TTR) is a protein with a growing number of biological functions in addition to its well-established binding and circulatory transport of thyroxine, and indirect retinoid transport through interaction with retinol-binding protein. Misfolded and aggregated wild-type and mutant TTRs are involved i...

journal_title：Endocrine research

authors： Fong VH,Wong S,Jintaridhi P,Vieira A

更新日期：2020-01-01 00:00:00

abstract：PURPOSE:Macrophage migration inhibitory factor (MIF) is a multifunctional cytokine that plays a role in metabolic and inflammatory processes. Increasing evidence suggests that there is a link between MIF and ovulation. We aimed to evaluate plasma MIF levels in women with polycystic ovary syndrome (PCOS) and to determin...

journal_title：Endocrine research

authors： Calan M,Kume T,Yilmaz O,Arkan T,Kocabas GU,Dokuzlar O,Aygün K,Oktan MA,Danıs N,Temur M

更新日期：2016-08-01 00:00:00

abstract：:Plasminogen activator inhibitor-1 (PAI-1) levels were found to be associated with obesity, indicating that adipocytes might influence PAI-1 plasma levels. In addition, the 4G/5G promoter polymorphism of the PAI-1 gene possibly modulates PAI-1 gene transcription and, as a consequence, PAI-1 plasma levels. Metabolic par...

journal_title：Endocrine research

authors： Zietz B,Buechler C,Drobnik W,Herfarth H,Schölmerich J,Schäffler A

更新日期：2004-08-01 00:00:00

abstract：:A 30-residue peptide corresponding to the amino acid sequence of steroidogenesis activator peptide (SAP) from rat Leydig tumor cells has been synthesized by the solid-phase method using Boc protection. SAP is the putative cycloheximide-sensitive, cAMP-regulated mediator of ACTH-stimulated conversion of cholesterol to ...

journal_title：Endocrine research

authors： Glass DB,Robertson DG,Xu TS,Bowman EP,Lambeth JD

更新日期：1991-01-01 00:00:00

abstract：:T3 receptors are ligand-dependent transcriptional activators that can stimulate gene expression resulting in growth and development. In this study T3 binding sites on isolated liver nuclei are demonstrated in the teleost Anabas testudineus. The effect of hypothyroidism and feeding of polyunsaturated fatty acids (PUFA)...

journal_title：Endocrine research

authors： Shameena B,Renuka TR,Varghese S,Paulose CS,Oommen OV

更新日期：2001-08-01 00:00:00

abstract：:Activation of calcium-activated, phospholipid-dependent protein kinase C by phorbol esters such as 12-O-tetradecanoyl-phorbol-13-acetate (TPA) has been shown to mediate release of hormones in many systems. To investigate the role of protein kinase C in the mechanism of pituitary ACTH release, we studied the effect of ...

journal_title：Endocrine research

authors： Sobel DO

更新日期：1988-01-01 00:00:00

abstract：:Atrial natriuretic peptide (ANP) is released from the atria and acts to regulate blood volume and pressure. The release of ANP appears to be stimulated by atrial distension, initiated by stretch on the cardiocytes. The purpose of the present study was to develop an assay that would allow for the detection of ANP relea...

journal_title：Endocrine research

authors： Miller HA 3rd,Southerland CM

更新日期：1990-01-01 00:00:00

abstract：:Dehydroepiandrosterone sulphate (DHEAS) is a steroid product of the adrenal gland, which circulates in high concentrations, but whose functions are largely unknown. There is evidence for antiproliferative effects of DHEAS in neoplastic tissue. The present study was designed to investigate the effects of DHEAS on vascu...

journal_title：Endocrine research

authors： Hinson JP,Khan M

更新日期：2004-11-01 00:00:00

abstract：:In the guinea pig adrenal the cells of the outer zone secrete high levels of steroid and respond to ACTH with increased synthesis of cholesterol and steroid. The outer zone consists of two cell types: zona fasciculata (ZF) and zona glomerulosa (ZG). To determine the relative contribution of ZF and ZG to the outer zone...

journal_title：Endocrine research

authors： Brody RI,Black VH

更新日期：1991-01-01 00:00:00

abstract：:Two CYP21 genes, the active CYP21 and the pseudogene, CYP21P, also pairs of duplicated genes including the XA, XB, XB-S; YA, YB; and ZA, ZB are arranged in tandem next to the serum complement C4 genes (C4A and C4B). In this report, we have analyzed the influence of some DNA sequences within the C4A/CYP21P region on th...

journal_title：Endocrine research

authors： Chang SF,Cheng CL

更新日期：1998-08-01 00:00:00

abstract：:Recent evidence supports the hypothesis that sympathetic neurons play a significant role in the regulation of adrenocortical cell proliferation and steroidogenesis. Co-cultures of rat adrenocortical and sympathetic ganglion cells have been established to study sympatho-adrenal interactions. In these studies we have co...

journal_title：Endocrine research

authors： Wu CH,Holzwarth MA

更新日期：1996-11-01 00:00:00

abstract：:Tumor-promoting phorbol esters are believed to affect cell functions by activating a Ca+2-and lipid-dependent protein kinase (protein kinase C). 12-0-Tetradecanoyl phorbol-13-acetate (TPA) inhibits LH stimulation of progesterone (P) accumulation in rat granulosa cells. To determine the mechanisms by which TPA inhibits...

journal_title：Endocrine research

authors： Kawai Y,Clark MR

更新日期：1986-01-01 00:00:00

abstract：:We have recently reported on the activities of glucose-6-phosphate dehydrogenase (G6PD), hexokinase (HK) and carbonic anhydrase I (CA-I) and II (CA-II) isoenzymes obtained from erythrocytes of healthy subjects and untreated patients with hyperthyroid diseases. Also, erythrocyte zinc concentrations were measured. Red b...

journal_title：Endocrine research

authors： Odçikin E,Ozdemir H,Ciftçi M,Capoğlu I

更新日期：2002-02-01 00:00:00

abstract：:Background: Evidence has shown that low thyroid hormone levels may lead to worse prognosis including a higher mortality rate in patients with heart failure (HF). Thyroid replacement increases cardiac output and exercise performance without causing significant adverse events. The purpose of this study is to compare lev...

journal_title：Endocrine research

authors： Yang T,Ruegger M,Colavecchia AC,Sadhu A,Patham B,Tatara A

更新日期：2020-02-01 00:00:00

abstract：:The MA-10 mouse Leydig tumor cell line produces large amounts of steroids only in response to hormonal stimulation while the R2C rat Leydig tumor cell line is constitutively steroidogenic in nature. In an effort to uncover the potential reasons for constitutive steroidogenesis in R2C cells, we have recently shown that...

journal_title：Endocrine research

authors： Rao RM,Jo Y,Babb-Tarbox M,Syapin PJ,Stocco DM

更新日期：2002-11-01 00:00:00

abstract：:Hashimoto's thyroiditis (HT) is one of the most common organ-specific autoimmune diseases. Increasing evidence indicates that HT may be characterized by an imbalance in the helper T cell subsets Th1 and Th2. Traditional Chinese Medicine (TCM) considers HT as a chronic exhaustion disease, leading to deficiency of qi. I...

journal_title：Endocrine research

authors： Chen J,Feng X,Huang Q

更新日期：2016-01-01 00:00:00

abstract：PURPOSE:Adiponectin and chemerin have been reported their associations with insulin resistance and chronic inflammation. However, the relationship between adiponectin and chemerin themselves has not been fully elucidated. Therefore, we investigated the effects of changes in adiponectin and chemerin levels after a weigh...

journal_title：Endocrine research

authors： Shin HY,Park S,Lee JW

更新日期：2017-11-01 00:00:00

abstract：:This study was performed on 18 postmenopausal female volunteers in order to examine changes in sex hormone binding globulin (SHBG), high density lipoprotein cholesterol (HDLC), total cholesterol (TC) and serum triglyceride (TG) levels in a period of four months of moderate physical exercise. While SHBG decreased signi...

journal_title：Endocrine research

authors： Caballero MJ,Maynar M

更新日期：1992-01-01 00:00:00

abstract：:In order to investigate the regulation of connexin distribution in rapidly growing cells, we evaluated the effects of dibutyryl cyclic adenosine monophosphate (DbcAMP) treatment on the cellular location of endogenous connexin 43 (Cx43) in an adrenal tumor cell population. Polyclonal antibodies to Cx43 and a Cx43 green...

journal_title：Endocrine research

authors： Wynn J,Shah U,Murray SA

更新日期：2002-11-01 00:00:00