Abstract:
BACKGROUND:Lifetime cost estimates are a useful tool in measuring the economic burden of HIV in the United States. Previous estimation methods need to be updated, given improving antiretroviral therapy regimens and updated costs. METHODS:We used an updated version of the agent-based model Progression and Transmission of HIV (PATH) 3.0 to reflect current regimens and costs. We simulated a cohort of those infected in 2015 until the last person had died to track the lifetime costs for treatment of HIV, including HIV health care utilization costs (inpatient, outpatient, opportunistic infection (OI) prophylaxis, non-HIV medication, and emergency department), OI treatment costs, and testing costs. We assumed a median per-person diagnosis delay of 3 years and a 3% base monthly probability of dropout from care for a base-case scenario. Additionally, we modeled a most-favorable scenario (median diagnosis delay of 1 year and 1% base dropout rate) and a least-favorable scenario (median diagnosis delay of 5 years and 5% base dropout rate). RESULTS:We estimated an average lifetime HIV-related medical cost for a person with HIV of $420,285 (2019 US$) discounted (3%) and $1,079,999 undiscounted for a median 3-year diagnosis delay and 3% base dropout rate. Our discounted cost estimate was $490,045 in our most-favorable scenario and $326,411 in our least-favorable scenario. CONCLUSIONS:Lifetime per-person HIV-related medical costs depend on the time from infection to diagnosis and the likelihood of dropping out of care. Our results, which are similar to previous studies, reflect updated ART regimens and costs for HIV treatment.
journal_name
Sex Transm Disjournal_title
Sexually transmitted diseasesauthors
Bingham A,Shrestha RK,Khurana N,Jacobson E,Farnham PGdoi
10.1097/OLQ.0000000000001366subject
Has Abstractpub_date
2021-01-23 00:00:00eissn
0148-5717issn
1537-4521pii
00007435-900000000-97769pub_type
杂志文章abstract:BACKGROUND:Chlamydia trachomatis infection is one of the most common sexually transmitted reported bacterial infections worldwide. The well-known sequelae of chlamydial infection include pelvic inflammatory disease and tubal factor infertility, but the evidence linking C. trachomatis infection and adverse pregnancy out...
journal_title:Sexually transmitted diseases
pub_type: 杂志文章
doi:10.1097/OLQ.0000000000000432
更新日期:2016-06-01 00:00:00
abstract::A solid-phase hemadsorption (SPHA) technique for the rapid detection of Treponema pallidum-specific IgM antibodies is described. The demonstration of these immunoglobulins permits differentiation between a recent and a long-lasting infection and facilitates the decision as to whether or not a patient should receive th...
journal_title:Sexually transmitted diseases
pub_type: 杂志文章
doi:
更新日期:1980-04-01 00:00:00
abstract:BACKGROUND:Lymphogranuloma venereum (LGV) has reestablished itself as an endemic sexually transmitted infection in the United Kingdom and elsewhere in Europe and North America over the last decade. Current guidelines suggest treatment with 21 days of doxycycline; however, the evidence base for LGV treatment including i...
journal_title:Sexually transmitted diseases
pub_type: 杂志文章
doi:10.1097/OLQ.0000000000000772
更新日期:2018-06-01 00:00:00
abstract:OBJECTIVES:To evaluate opportunities for earlier human immunodeficiency virus (HIV) diagnosis within a comprehensive public health care system. STUDY DESIGN:Retrospective review of newly diagnosed HIV-infected patients between September 2001 and December 2003. RESULTS:One hundred twenty of 348 (34%) newly diagnosed H...
journal_title:Sexually transmitted diseases
pub_type: 杂志文章
doi:10.1097/01.olq.0000194617.91454.3f
更新日期:2006-05-01 00:00:00
abstract:BACKGROUND:Black race is a risk marker for Chlamydia trachomatis infection. Because chlamydial serovar and race could both influence the transmission dynamics of chlamydia, studies characterizing serovars in a predominantly black population are of interest, yet remain sparse. STUDY DESIGN AND GOALS: C. trachomatis isol...
journal_title:Sexually transmitted diseases
pub_type: 杂志文章
doi:10.1097/01.olq.0000216027.71144.74
更新日期:2006-10-01 00:00:00
abstract:OBJECTIVE:The objective of this study was to determine levels of experience and knowledge concerning anal dysplasia, anal Pap smear tests, and human papillomavirus (HPV) among gay and other homosexually active men. STUDY DESIGN:Three hundred eighty-four men attending a large gay community event in Melbourne completed ...
journal_title:Sexually transmitted diseases
pub_type: 杂志文章
doi:10.1097/01.olq.0000230436.83029.ce
更新日期:2007-03-01 00:00:00
abstract:OBJECTIVE:This study aimed to provide a population-based estimate of human papillomavirus (HPV) seropositivity for women in a rural African context and to evaluate the impact of HPV serostatus on subsequent acquisition of HIV outside a clinical setting. DESIGN:A random sample of women participating in a longitudinal, ...
journal_title:Sexually transmitted diseases
pub_type: 杂志文章
doi:10.1097/OLQ.0b013e3182918578
更新日期:2013-07-01 00:00:00
abstract:BACKGROUND:Obstetric and gynecologic complications associated with bacterial vaginosis and trichomoniasis have heightened awareness of these conditions, and thus metronidazole's role in obstetric and gynecologic practice continues to increase. GOAL OF THIS STUDY:To review the clinical indications for metronidazole in ...
journal_title:Sexually transmitted diseases
pub_type: 杂志文章,评审
doi:
更新日期:1995-11-01 00:00:00
abstract:BACKGROUND:Studies of sexual behavior and of interventions designed to reduce human immunodeficiency virus risk usually depend on self-report. Validation of self-reported condom use measures has not been previously reported in an urban population at high risk for sexually transmitted diseases and human immunodeficiency...
journal_title:Sexually transmitted diseases
pub_type: 杂志文章
doi:10.1097/00007435-199501000-00003
更新日期:1995-01-01 00:00:00
abstract:BACKGROUND:High rates of sexually transmitted diseases (STDs) present an ongoing costly public health challenge. One approach to reduce STD transmission is to increase the number of clinicians adopting the Centers for Disease Control and Prevention's STD Treatment Guidelines. This evaluation assesses the effectiveness ...
journal_title:Sexually transmitted diseases
pub_type: 杂志文章
doi:10.1097/OLQ.0b013e3182045306
更新日期:2011-06-01 00:00:00
abstract::In light of the racial-ethnic and poverty composition of the United States population and the distribution of syphilis morbidity across population subgroups, it is important to determine how race-ethnicity and poverty jointly and independently affect transmission dynamics of syphilis and other sexually transmitted dis...
journal_title:Sexually transmitted diseases
pub_type: 杂志文章
doi:10.1097/00007435-199601000-00005
更新日期:1996-01-01 00:00:00
abstract:BACKGROUND:Studies of alcohol use and sexual behavior in African populations have primarily been cross-sectional, used nonvalidated measures of alcohol use, or relied on self-reported sexual risk endpoints. Few have focused on human immunodeficiency virus (HIV)-positive women. METHODS:Longitudinal data were collected ...
journal_title:Sexually transmitted diseases
pub_type: 杂志文章
doi:10.1097/OLQ.0000000000000502
更新日期:2016-10-01 00:00:00
abstract:BACKGROUND:A dye-based method for determining applicator usage in microbicide trials has been developed to assess whether applicators have been exposed to vaginal fluid. Our objective was to evaluate this method on polypropylene HTI applicators that are being widely used in several effectiveness trials of microbicides....
journal_title:Sexually transmitted diseases
pub_type: 杂志文章,多中心研究
doi:10.1097/OLQ.0b013e3181972397
更新日期:2009-06-01 00:00:00
abstract:BACKGROUND:Juvenile detention facilities house adolescents at high risk for sexually transmitted diseases. Collaboration between health departments and juvenile detention authorities can provide routine, cost-efficient chlamydia screening and treatment to females with limited access to care. We describe trends in scree...
journal_title:Sexually transmitted diseases
pub_type: 杂志文章
doi:10.1097/OLQ.0000000000000382
更新日期:2016-01-01 00:00:00
abstract:BACKGROUND AND OBJECTIVES:This study describes self-reported histories of sexually transmitted diseases (STD) with respect to gender and ethnicity and examines the factors that influence the use of condoms among heterosexual users of injection drugs and/or crack cocaine. STUDY DESIGN:A cross-sectional design was used ...
journal_title:Sexually transmitted diseases
pub_type: 杂志文章,多中心研究
doi:10.1097/00007435-199607000-00006
更新日期:1996-07-01 00:00:00
abstract:OBJECTIVE:To determine the prevalence of sexually transmitted diseases (STDs) and characterize behavioral correlates among pregnant women attending inner city public STD clinics. STUDY DESIGN:A retrospective study of 2303 pregnant women frequency matched by clinic and year of visit to 2303 nonpregnant women seeking se...
journal_title:Sexually transmitted diseases
pub_type: 杂志文章
doi:10.1097/olq.0b013e31812e6b9a
更新日期:2007-12-01 00:00:00
abstract:OBJECTIVES:We conducted formative research to evaluate the acceptability and feasibility of continuous diaphragm use among low-income women highly exposed to sexually transmitted infections (STIs) in Madagascar. GOAL:To identify potential obstacles to researching the effectiveness of diaphragm use for STI prevention i...
journal_title:Sexually transmitted diseases
pub_type: 杂志文章
doi:10.1097/OLQ.0b013e31815abaa2
更新日期:2008-03-01 00:00:00
abstract:BACKGROUND:Douching may interfere with determination of microbicide safety and effectiveness. This practice has not been adequately studied among women at risk of HIV infection. GOAL:This study assessed douching practices among women at risk of HIV infection in the United States. STUDY DESIGN:Data were collected on d...
journal_title:Sexually transmitted diseases
pub_type: 杂志文章
doi:10.1097/00007435-200207000-00008
更新日期:2002-07-01 00:00:00
abstract::Strains of Neisseria gonorrhoeae requiring arginine, hypoxanthine, and uracil (AHU) may cause disseminated gonococcal infection (DGI). A significant epidemiologic association was noted between the incidence of disseminated gonococcal infection and the presence of gonococci of the AHU auxotype in the community over a n...
journal_title:Sexually transmitted diseases
pub_type: 杂志文章
doi:10.1097/00007435-198404000-00003
更新日期:1984-04-01 00:00:00
abstract:BACKGROUND AND OBJECTIVES:To obtain patients' perspectives on why only some partners are notified in partner-notification programs, the cornerstone of sexually transmitted disease (STD) control, although low proportions of partners are located and evaluated. GOALS:To describe patterns of partner notification reported ...
journal_title:Sexually transmitted diseases
pub_type: 杂志文章
doi:10.1097/00007435-200004000-00003
更新日期:2000-04-01 00:00:00
abstract::The concentration of the protein CA-125 in serum was determined in women with a normal pelvis visualized at laparoscopy (control group, n = 15) and compared with serum levels of this protein in women with pelvic inflammatory disease (PID) (n = 14). Mean serum concentrations of CA-125 were similar in the two groups: 17...
journal_title:Sexually transmitted diseases
pub_type: 杂志文章
doi:10.1097/00007435-198807000-00005
更新日期:1988-07-01 00:00:00
abstract:BACKGROUND:Since the early 1980s, the Bahamas has experienced sequential epidemics of freebase/crack cocaine use, genital ulcer-inguinal adenopathy disease (GUD), and heterosexual HIV infection. GOAL:To prospectively define the etiology of GUD in patients at the Princess Margaret Hospital during outbreaks of crack coc...
journal_title:Sexually transmitted diseases
pub_type: 杂志文章
doi:10.1097/00007435-200205000-00001
更新日期:2002-05-01 00:00:00
abstract:BACKGROUND:The ability to seek help or medical care for sexually transmitted infections (STIs) is vital for sexually active youth; yet, their needs are often unmet. METHODS:We conducted a qualitative systematic review of studies to assess youth and provider views about the behaviors of young people in help seeking and...
journal_title:Sexually transmitted diseases
pub_type: 杂志文章,meta分析,评审
doi:10.1097/OLQ.0000000000000607
更新日期:2017-06-01 00:00:00
abstract:BACKGROUND:To study the incidence, persistence, and determinants of human papillomavirus (HPV) infection in a population of Inuit women from Nunavik, Quebec, by overall HPV infection, Alphapapillomavirus (α) species, and oncogenic risk grouping. METHODS:We recruited a cohort of Inuit women living in communities in Nun...
journal_title:Sexually transmitted diseases
pub_type: 杂志文章
doi:10.1097/OLQ.0000000000000272
更新日期:2015-05-01 00:00:00
abstract:OBJECTIVES:Two of the major diagnostic methods for Trichomonas vaginalis, wet mount and culture, rely on the continued viability of the organism. Methods to increase the viability of T. vaginalis in urine are needed. GOAL:The goal of this study was to develop a method that increases the time of viability of T. vaginal...
journal_title:Sexually transmitted diseases
pub_type: 杂志文章
doi:10.1097/01.olq.0000249724.72816.a0
更新日期:2007-07-01 00:00:00
abstract:BACKGROUND:Male circumcision (MC) decreases the risk of human immunodeficiency virus (HIV) acquisition in men. We explored associations between MC of the primary sex partner and women's risk of acquisition of chlamydial (Ct), gonococcal (GC), or trichomonal (Tv) infections. METHODS:We analyzed data from a prospective ...
journal_title:Sexually transmitted diseases
pub_type: 杂志文章
doi:10.1097/OLQ.0b013e31816b1fcc
更新日期:2008-07-01 00:00:00
abstract:BACKGROUND AND OBJECTIVES:The basic reproductive rate of and STD is an important parameter from which the success of intervention strategies can be predicted. GOAL OF THE STUDY:To evaluate different methods to estimate the basic reproductive rate. RESULTS:Two different methods of estimating the basic reproductive rat...
journal_title:Sexually transmitted diseases
pub_type: 杂志文章
doi:10.1097/00007435-199411000-00010
更新日期:1994-11-01 00:00:00
abstract::60 women with bacterial vaginosis were entered into a double blind, placebo-controlled treatment trial with lyophilized Lactobacillus acidophilus. The lactobacilli used were producing H2O2. Immediately after completion of treatment, 16 out of 28 women who were treated with lactobacilli had normal vaginal wet smear res...
journal_title:Sexually transmitted diseases
pub_type: 临床试验,杂志文章,随机对照试验
doi:10.1097/00007435-199205000-00007
更新日期:1992-05-01 00:00:00
abstract:BACKGROUND:Only a few studies have investigated the etiology of acute pelvic inflammatory disease (PID) in laparoscopy-proven cases using pelvic samples for culture. Most of these studies were conducted in North America and Scandinavia. GOAL OF THE STUDY:To study the microbial etiology of laparoscopy-proven acute pelv...
journal_title:Sexually transmitted diseases
pub_type: 杂志文章
doi:10.1097/00007435-199305000-00008
更新日期:1993-05-01 00:00:00
abstract:GOAL:To determine prevalence and incidence of Neisseria gonorrhoeae (GC) and Chlamydia trachomatis (CT) infection and assess risk factors predictive for such infections in a middle school-based clinic sample. STUDY DESIGN:170 female students and 43 male students making 256 and 47 visits, respectively, > or = 30 days a...
journal_title:Sexually transmitted diseases
pub_type: 杂志文章
doi:10.1097/00007435-199809000-00001
更新日期:1998-09-01 00:00:00