[The principles of the treatment of pancreatic diabetes].

Abstract:

:In pancreatic diabetes the whole of the Langerhans islets are damaged, which means that both the beta-cells and the alpha-cells are damaged. Unpredictable oscillations of blood glucose level are common due to malabsorption and maldigestion and one may count with explicit proneness to hypoglycaemia. The defence against hypoglycaemia also diminishes due to the damage of glucagon secretion, which is often aggravated by alcohol consumption. If normoglycaemia in pancreas diabetes cannot be achieved with appropriate diet, insulin treatment is necessary. Oral antidiabetic agents are not expedient. The best metabolic state can be achieved at the expense of the least amount of hypoglycaemia by giving the necessary minimum portions of insulin in an intensive, conservative insulin therapy. There is not enough experience with insulin analogs in pancreatic diabetes, but it seems expedient to use long-acting insulin analogs. The treatment of pancreas diabetes is a teamwork in which everybody has a decisive role, the gastroenterologist, the diabetologist, the dietitian and the diabetes nurse as well.

journal_name

Orv Hetil

journal_title

Orvosi hetilap

authors

Iván G

doi

10.1556/OH.2009.28486

subject

Has Abstract

pub_date

2009-02-08 00:00:00

pages

273-6

issue

6

eissn

0030-6002

issn

1788-6120

pii

66M70238H0606383

journal_volume

150

pub_type

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