Application of thermography in the diagnostic investigation of thyroid nodules.

Abstract:

:Thyroid nodules (TN) are common in the general population, and the clinical importance of diagnosing thyroid nodules is based on excluding the possibility of thyroid cancer, which occurs in 7-15% of cases. The thyroid gland, owing to its superficial location, is easily accessible via thermography, a noninvasive method of recording body temperature that measures infrared radiation emitted by the body surface. Therefore, this study aimed to evaluate the temperature differences between benign and malignant TN by using thermography. We conducted a cross-sectional study where 147 TN were divided into two groups: the first group included 120 benign nodules and the other included 27 malignant nodules. All the nodules were subjected to ultrasound, fine needle aspiration biopsy, and thermography. On analyzing the thermography results, the benign nodules had a higher temperature at the beginning of the thermography evaluation, and the malignant nodules showed a higher temperature in the middle and at the end (Ft). Using the relationships, it was observed that the temperature delta (ΔT), ΔT nodule/ΔT healthy, ΔT nodule minus ΔT healthy, and nodule Ft minus Ft of the healthy region were higher in malignant nodules. The ROC curve analysis of ΔT demonstrated a cutoff point of 2.38°C, with a sensitivity of 0.963 and specificity of 0.992. Malignant nodules have higher temperatures than benign nodules on thermographic evaluation. This finding suggests that thermography can be a useful tool in the diagnosis of thyroid nodules.

journal_name

Endocr J

journal_title

Endocrine journal

authors

Damião CP,Montero JRG,Moran MBH,de Oliveira Marçal E Silva Carvalho ME,de Farias CG,Brito IB,Saad MAN,Fontes CAP,Fainstein C,Rodrigues MFO,Palombo A,Conci A,da Cruz Filho RA,Lima GAB

doi

10.1507/endocrj.EJ20-0541

subject

Has Abstract

pub_date

2021-01-21 00:00:00

eissn

0918-8959

issn

1348-4540

pub_type

杂志文章
  • Prognosis and growth activity depend on patient age in clinical and subclinical papillary thyroid carcinoma.

    abstract::In this review, we focused on the patient age as an indicator of tumor growth and prognostic significance in both clinical papillary thyroid carcinoma (PTC) and subclinical papillary microcarcinoma (PMC: PTC ≤ 1 cm). In clinical PTC, young age (< 30 years) and old age (≥ 60 years) significantly affected the disease-fr...

    journal_title:Endocrine journal

    pub_type: 杂志文章,评审

    doi:10.1507/endocrj.ej13-0403

    authors: Ito Y,Miyauchi A,Kobayashi K,Miya A

    更新日期:2014-01-01 00:00:00

  • Pioglitazone reduces ER stress in the liver: direct monitoring of in vivo ER stress using ER stress-activated indicator transgenic mice.

    abstract::It is known that endoplasmic reticulum (ER) stress is provoked under diabetic conditions and is possibly involved in the development of insulin resistance. In this study, using ER stress-activated indicator (ERAI) transgenic mice which express green fluorescent protein under ER stress conditions, we directly evaluated...

    journal_title:Endocrine journal

    pub_type: 杂志文章

    doi:10.1507/endocrj.k09e-140

    authors: Yoshiuchi K,Kaneto H,Matsuoka TA,Kasami R,Kohno K,Iwawaki T,Nakatani Y,Yamasaki Y,Shimomura I,Matsuhisa M

    更新日期:2009-01-01 00:00:00

  • Successful management of a patient with active Cushing‍'‍s disease complicated with coronavirus disease 2019 (COVID-19) pneumonia.

    abstract::We provide the details of the successful management of a patient with active Cushing's disease complicated with coronavirus disease 2019 (COVID-19) pneumonia. The patient was a 27-year-old Japanese female healthcare worker who was scheduled to undergo pituitary surgery for Cushing's disease. She had been in close cont...

    journal_title:Endocrine journal

    pub_type: 杂志文章

    doi:10.1507/endocrj.EJ20-0613

    authors: Yuno A,Kenmotsu Y,Takahashi Y,Nomoto H,Kameda H,Cho KY,Nakamura A,Yamashita Y,Nakamura J,Nakakubo S,Kamada K,Suzuki M,Sugino H,Inoshita N,Konno S,Miyoshi H,Atsumi T,Sawamura Y,Shimatsu A

    更新日期:2020-12-24 00:00:00

  • Pancreas volume reduction and metabolic effects in Japanese patients with severe obesity following laparoscopic sleeve gastrectomy.

    abstract::This study aimed to assess the relationship between the metabolic effect after laparoscopic sleeve gastrectomy (LSG) in morbidly obese Japanese patients, with or without type 2 diabetes mellitus (T2DM), and improved pancreatic steatosis (PS). The study enrolled 27 morbidly obese Japanese patients who were undergoing L...

    journal_title:Endocrine journal

    pub_type: 杂志文章

    doi:10.1507/endocrj.EJ16-0321

    authors: Umemura A,Sasaki A,Nitta H,Baba S,Ando T,Kajiwara T,Ishigaki Y

    更新日期:2017-05-30 00:00:00

  • Association of osteoporosis susceptibility genes with bone mineral density and bone metabolism related markers in Koreans: the Chungju Metabolic Disease Cohort (CMC) study.

    abstract::In this study, we evaluated the association between bone mineral density (BMD) and 10 single-nucleotide polymorphisms (SNPs) within eight osteoporosis susceptibility genes that were previously identified in genome-wide association studies (GWASs). A total of 494 men and 493 postmenopausal women participating in the Ch...

    journal_title:Endocrine journal

    pub_type: 杂志文章

    doi:10.1507/endocrj.ej14-0119

    authors: Park SE,Oh KW,Lee WY,Baek KH,Yoon KH,Son HY,Lee WC,Kang MI

    更新日期:2014-01-01 00:00:00

  • Immunoglobulin G can cross-react with glucagon antisera and cause a spuriously high plasma immunoreactive glucagon level.

    abstract::We had a patient with asymptomatic hyper-immunoreactive glucagonemia and with no evidence of pancreatic tumor detected by radiological examinations. The glucagon level was not decreased by the administration of glucose or somatosatin analogue (SMS 201-995). Gel filtration studies revealed that most glucagon immunoreac...

    journal_title:Endocrine journal

    pub_type: 杂志文章

    doi:10.1507/endocrj.42.455

    authors: Hattori N,Saiki Y,Kajikawa M,Ishihara T,Moridera K,Hino M,Ikekubo K,Kurahachi H

    更新日期:1995-08-01 00:00:00

  • Tyrosine-kinase inhibitors to treat radioiodine-refracted, metastatic, or recurred and progressive differentiated thyroid carcinoma [Review].

    abstract::Differentiated thyroid carcinoma (DTC) is generally indolent in nature and, even though it metastasizes to distant organs, the prognosis is normally excellent. In contrast, the overall survival (OS) of patients with radioactive iodine (RAI)-refractory and progressive metastases is dire, because no effective therapies ...

    journal_title:Endocrine journal

    pub_type: 杂志文章,评审

    doi:10.1507/endocrj.EJ16-0064

    authors: Ito Y,Suzuki S,Ito K,Imai T,Okamoto T,Kitano H,Sugitani I,Sugino K,Tsutsui H,Hara H,Yoshida A,Shimizu K

    更新日期:2016-07-30 00:00:00

  • The role of small proliferative adipocytes in the development of obesity: comparison between Otsuka Long-Evans Tokushima Fatty (OLETF) rats and non-obese Long-Evans Tokushima Otsuka (LETO) rats.

    abstract::Obesity consists of hypertrophy and hyperplasia of adipocytes. Although the number of adipocytes is influenced by anatomical location, nutritional environment, hormone and genetic variation, it has been thought to be determined by the proliferation of precursor cells and subsequent differentiation. However, our recent...

    journal_title:Endocrine journal

    pub_type: 杂志文章

    doi:10.1507/endocrj.ej13-0053

    authors: Hanamoto T,Kajita K,Mori I,Ikeda T,Fujioka K,Yamauchi M,Okada H,Usui T,Takahashi N,Kitada Y,Taguchi K,Kajita T,Uno Y,Morita H,Ishizuka T

    更新日期:2013-01-01 00:00:00

  • Role of copper ion in the pathogenesis of type 2 diabetes.

    abstract::Reactive oxygen species (ROS) are induced under diabetic conditions and are likely associated with the development of type 2 diabetes. It is also known that ROS production is facilitated in the presence of copper ion through the Fenton reaction. The aim of this study was to examine the involvement of copper ion in the...

    journal_title:Endocrine journal

    pub_type: 杂志文章

    doi:10.1507/endocrj.k09e-051

    authors: Tanaka A,Kaneto H,Miyatsuka T,Yamamoto K,Yoshiuchi K,Yamasaki Y,Shimomura I,Matsuoka TA,Matsuhisa M

    更新日期:2009-01-01 00:00:00

  • Growth of an aggressive tumor during pregnancy in an acromegalic patient.

    abstract::Pregnancy in acromegalic patients is a rare event, but is usually uneventful, with stable GH and IGF-I levels and no tumor enlargement. Medical treatment can usually be withdrawn without problems and although no major adverse event has been reported, the suspension of drug treatments is generally recommended. No cas...

    journal_title:Endocrine journal

    pub_type: 杂志文章

    doi:10.1507/endocrj.ej11-0306

    authors: Kasuki L,Neto LV,Takiya CM,Gadelha MR

    更新日期:2012-01-01 00:00:00

  • Identification of chromosome 15q26 terminal deletion with telomere sequences and its bearing on genotype-phenotype analysis.

    abstract::We report a de novo heterozygous 5,013,940 bp terminal deletion of chromosome 15q26 in a 13 9/12 -year-old Japanese girl with short stature (-3.9 SD), mild mental retardation, and ventricular septal defect (VSD). This terminal deletion involved IGF1R but not NR2F2, and was associated with an addition of telomere repea...

    journal_title:Endocrine journal

    pub_type: 杂志文章

    doi:10.1507/endocrj.k10e-251

    authors: Dateki S,Fukami M,Tanaka Y,Sasaki G,Moriuchi H,Ogata T

    更新日期:2011-01-01 00:00:00

  • Follicular thyroid carcinoma: From diagnosis to treatment.

    abstract::Unusual presentations with bone, lung or soft tissue metastases in initial diagnosis of follicular thyroid carcinoma have been reported occasionally. This implies how difficult it is to diagnosis this type of cancer at the pre-operative or intra-operative stage of treatment. Fine needle aspiration cytology has been sh...

    journal_title:Endocrine journal

    pub_type: 杂志文章,评审

    doi:10.1507/endocrj.kr-77

    authors: Lin JD,Chao TC

    更新日期:2006-08-01 00:00:00

  • A case of nonfunctioning pituitary adenoma resembling so-called silent corticotroph adenoma.

    abstract::It has been indicated that some subsets of clinically nonfunctioning pituitary adenoma exhibit immunohistochemical and ultrastructural features of somatotroph or corticotroph cells, which are described as silent somatotroph and corticotroph adenomas, respectively. We here describe a 70-year-old woman with nonfunctioni...

    journal_title:Endocrine journal

    pub_type: 杂志文章

    doi:10.1507/endocrj.44.329

    authors: Sakaguchi H,Koshiyama H,Sano T,Inoue D,Hashimoto N,Aoki N,Nakao K

    更新日期:1997-04-01 00:00:00

  • A somatotropin-producing pituitary adenoma with an isolated adrenocorticotropin-producing pituitary adenoma in a female patient with acromegaly, subclinical Cushing's disease and a left adrenal tumor.

    abstract::A 67-year-old female with hypertension and impaired glucose tolerance was admitted to our hospital because of a typical acromegalic appearance, including large, thickened bulky hands and feet, and a large prominent forehead and tongue. She did not have a Cushingoid appearance, such as a moon-face, buffalo hump, purple...

    journal_title:Endocrine journal

    pub_type: 杂志文章

    doi:10.1507/endocrj.ej14-0093

    authors: Kobayashi Y,Takei M,Ohkubo Y,Kakizawa Y,Matoba H,Kumagai M,Takeda T,Suzuki S,Komatsu M

    更新日期:2014-01-01 00:00:00

  • Anti-alpha-enolase antibodies in pituitary disease.

    abstract::A previous study reported a high prevalence of autoantibodies to alpha-enolase in lymphocytic hypophysitis and these antibodies efficiently distinguished lymphocytic hypophysitis from pituitary tumors. To confirm this, we examined autoantibodies to alpha-enolase in patients with lymphocytic hypophysitis (n = 17), pitu...

    journal_title:Endocrine journal

    pub_type: 杂志文章

    doi:10.1507/endocrj.50.697

    authors: Tanaka S,Tatsumi KI,Takano T,Murakami Y,Takao T,Yamakita N,Tahara S,Teramoto A,Hashimoto K,Kato Y,Amino N

    更新日期:2003-12-01 00:00:00

  • Tumor necrosis factor-alpha (TNF-alpha) inhibits insulin-like growth factor-I (IGF-I) activities in human trophoblast cell cultures through IGF-I/insulin hybrid receptors.

    abstract::Tumor necrosis factor-alpha (TNF-alpha) in placenta is believed to be involved in pathogenesis of intrauterine growth restriction. In contrast, insulin-like growth factors (IGFs) are believed to be important for stimulation of fetal and placental growth. IGF-I stimulates metabolic and growth-promoting actions directly...

    journal_title:Endocrine journal

    pub_type: 杂志文章

    doi:10.1507/endocrj.k09e-189

    authors: Hashimoto R,Sakai K,Matsumoto H,Iwashita M

    更新日期:2010-01-01 00:00:00

  • Cavernous sinus invasion and tumor proliferative potential of growth hormone-producing pituitary tumors.

    abstract:PURPOSE:Surgical removal of growth hormone-producing pituitary adenomas (GHomas) becomes difficult when they invade the cavernous sinus (CS). We investigated the relation among tumor proliferative potential, tumor volume and invasion of GHomas to CS. MATERIALS & METHODS:15 patients with GHoma aged 20-59 years were enr...

    journal_title:Endocrine journal

    pub_type: 杂志文章

    doi:10.1507/endocrj.47.supplmarch_s77

    authors: Iuchi S,Saeki N,Uchino Y,Higuchi Y,Tatsuno I,Nakamura S,Yasuda T,Yamaura A

    更新日期:2000-03-01 00:00:00

  • Hypertension in acromegaly: hereditary hypertensive factor produces hypertension by enhancing IGF-I production.

    abstract::Sixty-four patients with acromegaly were retrospectively analyzed to study the incidence and cause of hypertension in acromegaly. WHO criteria indicate that 37.5% patients with acromegaly have hypertension. The blood pressure was positively correlated with age, the insulin-like growth factor I (IGF-I) and serum sodium...

    journal_title:Endocrine journal

    pub_type: 历史文章,杂志文章

    doi:10.1507/endocrj.42.781

    authors: Ohtsuka H,Komiya I,Aizawa T,Yamada T

    更新日期:1995-12-01 00:00:00

  • Adult-onset hypogonadotropic hypogonadism caused by aberrant expression of aromatase in an adrenocortical adenocarcinoma.

    abstract::Estrogen-secreting adrenal cancers are extremely rare, with feminizing symptoms attributed to aromatase expression in the adrenal tumor. We describe a case of hypogonadotropic hypogonadism as a consequence of aberrant aromatase expression in a patient with adrenocortical adenocarcinoma. A 54 year-old man presented wit...

    journal_title:Endocrine journal

    pub_type: 杂志文章

    doi:10.1507/endocrj.k10e-046

    authors: Advani A,Johnson SJ,Nicol MR,Papacleovoulou G,Evans DB,Vaikkakara S,Mason JI,Quinton R

    更新日期:2010-01-01 00:00:00

  • The evolution of non-diabetic hyperglycemia: a longitudinal study.

    abstract::The risk factors for impaired fasting glucose (IFG) and impaired glucose tolerance (IGT) have yet to be established. Our aim was to elucidate the predisposing factors for IFG and IGT in Japanese subjects with normal glucose tolerance (NGT). Using a 75 g oral glucose tolerance test (OGTT), we analyzed 604 adults with t...

    journal_title:Endocrine journal

    pub_type: 杂志文章

    doi:10.1507/endocrj.ej13-0359

    authors: Oka R,Yagi K,Hayashi K,Kawashiri MA,Yamagishi M,Yamada M,Fumisawa Y,Yamauchi K,Aizawa T

    更新日期:2014-01-01 00:00:00

  • Association between serum ferritin and circulating oxidized low-density lipoprotein levels in patients with type 2 diabetes.

    abstract::The oxidative modification of low-density lipoproteins (LDL) plays a central role in the initiation and acceleration of atherosclerosis. Iron plays a part in the formation of highly toxic free radicals such as hydroxide and superoxide anions, which can induce lipid peroxidation. We investigated whether serum iron stat...

    journal_title:Endocrine journal

    pub_type: 杂志文章

    doi:10.1507/endocrj.k06-010

    authors: Ikeda Y,Suehiro T,Yamanaka S,Kumon Y,Takata H,Inada S,Ogami N,Osaki F,Inoue M,Arii K,Hashimoto K

    更新日期:2006-10-01 00:00:00

  • A novel frameshift mutation in NR3C2 leads to decreased expression of mineralocorticoid receptor: a family with renal pseudohypoaldosteronism type 1.

    abstract::Pseudohypoaldosteronism type 1 (PHA1) is a rare genetic disease characterized by resistance to aldosterone, and the renal form of PHA1 is associated with heterozygous inactivating mutations in NR3C2, which encodes mineralocorticoid receptor (MR). Here we report a case of renal PHA1 due to a novel frameshift mutation i...

    journal_title:Endocrine journal

    pub_type: 杂志文章

    doi:10.1507/endocrj.EJ16-0280

    authors: Kawashima Sonoyama Y,Tajima T,Fujimoto M,Hasegawa A,Miyahara N,Nishimura R,Hashida Y,Hayashi A,Hanaki K,Kanzaki S

    更新日期:2017-01-30 00:00:00

  • An acromegalic patient with pulsatile secretion of growth hormone (GH) coincident with the slow-wave sleep.

    abstract::A 43-year-old woman was admitted to our hospital for further treatment of acromegaly with high plasma GH and IGF-I levels after transsphenoidal adenomectomy and subsequent treatment with bromocriptine. Physical examination and magnetic resonance imaging (MRI) showed an active acromegalic appearance with residual pitui...

    journal_title:Endocrine journal

    pub_type: 杂志文章

    doi:10.1507/endocrj.45.687

    authors: Matsuno M,Sohmiya M,Yamamoto H,Kato Y

    更新日期:1998-10-01 00:00:00

  • Concentration of the n-octanoylated active form of ghrelin in fetal and neonatal circulation.

    abstract::The octanoylation of Ser3 is essential for the biological function of ghrelin. We examined the concentrations of the n-octanoylated active-form ghrelin in cord and neonatal blood using an RIA system that specifically recognized n-octanoylated ghrelin, as well as a system that measured the total ghrelin concentration. ...

    journal_title:Endocrine journal

    pub_type: 杂志文章

    doi:10.1507/endocrj.52.271

    authors: Yokota I,Kitamura S,Hosoda H,Kotani Y,Kangawa K

    更新日期:2005-04-01 00:00:00

  • Plasma angiotensin II, renin activity and serum angiotensin-converting enzyme activity in non-insulin dependent diabetes mellitus patients with diabetic nephropathy.

    abstract::The renin-angiotensin system (RAS) has been unequivocally implicated as a mediator of diabetic complications. The present study was designed to evaluate the RAS in non-insulin dependent diabetic patients with diabetic nephropathy. Plasma renin activity, plasma angiotensin II and serum angiotensin-converting enzyme (AC...

    journal_title:Endocrine journal

    pub_type: 杂志文章

    doi:10.1507/endocrj.48.25

    authors: Nicola W,Sidhom G,El Khyat Z,Ibrahim S,Salah A,El Sayed A

    更新日期:2001-02-01 00:00:00

  • Distribution of serum immunoglobulin G4 levels in Hashimoto's thyroiditis and clinical features of Hashimoto's thyroiditis with elevated serum immunoglobulin G4 levels.

    abstract::Immunoglobulin G4-related disease (IgG4-RD) is characterized by elevated serum IgG4 levels, IgG4-positive plasmacytes, and lymphocyte infiltration into multiple organs. IgG4 thyroiditis is a subset of patients with Hashimoto's thyroiditis (HT) who exhibited histopathological features of IgG4-RD; its source of serum Ig...

    journal_title:Endocrine journal

    pub_type: 杂志文章

    doi:10.1507/endocrj.EJ15-0157

    authors: Takeshima K,Ariyasu H,Inaba H,Inagaki Y,Yamaoka H,Furukawa Y,Doi A,Furuta H,Nishi M,Akamizu T

    更新日期:2015-01-01 00:00:00

  • Inhibitory effects of trichostatin A on adrenocorticotropic hormone production and proliferation of corticotroph tumor AtT-20 cells.

    abstract::Cushing's disease is primarily caused by adrenocorticotropic hormone (ACTH)-producing pituitary adenomas. Pituitary tumor-transforming gene 1 (PTTG1) expression, a hallmark of pituitary tumors, stimulates pituitary cell proliferation. Histone deacetylases (HDACs) play an important role in regulating gene transcription...

    journal_title:Endocrine journal

    pub_type: 杂志文章

    doi:10.1507/endocrj.EJ15-0369

    authors: Nakada Y,Kageyama K,Sugiyama A,Desaki R,Takayasu S,Niioka K,Murasawa S,Ishigame N,Asari Y,Iwasaki Y,Daimon M

    更新日期:2015-01-01 00:00:00

  • Antidiabetic effects of an oral administration of Lactobacillus casei in a non-insulin-dependent diabetes mellitus (NIDDM) model using KK-Ay mice.

    abstract::The antidiabetic effects of Lactobacillus casei (LC) on a non-insulin-dependent diabetes mellitus (NIDDM) model, KK-Ay mice, were investigated. The oral administration of LC to male 4-week-old KK-Ay mice, or raising the mice on a 0.05% LC-containing diet significantly decreased the plasma glucose at 8 to 10 weeks of a...

    journal_title:Endocrine journal

    pub_type: 杂志文章

    doi:10.1507/endocrj.44.357

    authors: Matsuzaki T,Yamazaki R,Hashimoto S,Yokokura T

    更新日期:1997-06-01 00:00:00

  • Analysis of the KAL1 gene in 19 Japanese patients with Kallmann syndrome.

    abstract::Kallmann syndrome is defined by the association of hypogonadotropic hypogonadism and anosmia. The KAL1 gene is responsible for the X-linked form of Kallmann syndrome. We analyzed the KAL1 gene in 19 Japanese patients with Kallmann syndrome, including 3 patients reported previously, using PCR-direct sequencing method. ...

    journal_title:Endocrine journal

    pub_type: 杂志文章

    doi:10.1507/endocrj.48.143

    authors: Izumi Y,Tatsumi K,Okamoto S,Ogawa T,Hosokawa A,Matsuo T,Kato Y,Fukui H,Amino N

    更新日期:2001-04-01 00:00:00

  • Diagnosis of central diabetes insipidus using a vasopressin radioimmunoassay during hypertonic saline infusion.

    abstract::Central diabetes insipidus (CDI) is characterized by polyuria and polydipsia caused by impairment of arginine vasopressin (AVP) secretion. In this study, we evaluated plasma AVP concentrations during a hypertonic saline infusion test using a new AVP radioimmunoassay (RIA) which is now available in Japan. Thirteen cont...

    journal_title:Endocrine journal

    pub_type: 杂志文章

    doi:10.1507/endocrj.EJ19-0224

    authors: Takagi H,Hagiwara D,Handa T,Sugiyama M,Onoue T,Tsunekawa T,Ito Y,Iwama S,Goto M,Suga H,Banno R,Takahashi K,Matsui S,Arima H

    更新日期:2020-03-28 00:00:00